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Expert Review of Clinical Immunology Volume 10, 2014 - Issue 12
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Intravenous immunoglobulin as treatment for myasthenia gravis: current evidence and outcomes

Majed AlabdaliDivision of Neurology, Department of Medicine, Toronto General Hospital, University Health Network, University of Toronto, 200 Elizabeth St, Toronto, Ontario, M5A 4H9, Canada
,
Carolina BarnettDivision of Neurology, Department of Medicine, Toronto General Hospital, University Health Network, University of Toronto, 200 Elizabeth St, Toronto, Ontario, M5A 4H9, Canada
,
Hans KatzbergDivision of Neurology, Department of Medicine, Toronto General Hospital, University Health Network, University of Toronto, 200 Elizabeth St, Toronto, Ontario, M5A 4H9, Canada
,
Ari BreinerDivision of Neurology, Department of Medicine, Toronto General Hospital, University Health Network, University of Toronto, 200 Elizabeth St, Toronto, Ontario, M5A 4H9, Canada
&
Vera BrilCorrespondence[email protected]
Pages 1659-1665 | Published online: 20 Oct 2014

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Shuhui Wang, Iva Breskovska, Shreya Gandhy, Anna Rostedt Punga, Jeffery T. Guptill & Henry J. Kaminski. (2018) Advances in autoimmune myasthenia gravis management. Expert Review of Neurotherapeutics 18:7, pages 573-588.
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Articles from other publishers (26)

David S. Younger. 2023. Motor System Disorders, Part I: Normal Physiology and Function and Neuromuscular Disorders. Motor System Disorders, Part I: Normal Physiology and Function and Neuromuscular Disorders 707 777 .
David S. Younger. 2023. Motor System Disorders, Part I: Normal Physiology and Function and Neuromuscular Disorders. Motor System Disorders, Part I: Normal Physiology and Function and Neuromuscular Disorders 315 358 .
Cristina Segú-Vergés, Silvia Caño, Elisabeth Calderón-Gómez, Helena Bartra, Teresa Sardon, Srini Kaveri & José Terencio. (2022) Systems biology and artificial intelligence analysis highlights the pleiotropic effect of IVIg therapy in autoimmune diseases with a predominant role on B cells and complement system. Frontiers in Immunology 13.
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Marina Mané-Damas, Peter C. Molenaar, Peter Ulrichts, Florit Marcuse, Marc H. De Baets, Pilar Martinez-Martinez & Mario Losen. (2022) Novel treatment strategies for acetylcholine receptor antibody-positive myasthenia gravis and related disorders. Autoimmunity Reviews 21:7, pages 103104.
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Seung Ah Kang, Megan Sweeney & Raghav Govindarajan. (2022) Academic and Employment Status in Patients With Generalized Myasthenia Gravis Treated With Eculizumab: A Case Series. Journal of Clinical Neuromuscular Disease 23:4, pages 210-218.
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Eric M. Tichy, Barbara Prosser & Drew Doyle. (2020) Expanding the Role of the Pharmacist: Immunoglobulin Therapy and Disease Management in Neuromuscular Disorders. Journal of Pharmacy Practice 35:1, pages 106-119.
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Shin J. Oh. 2022. Neuromuscular Disorders. Neuromuscular Disorders 446 491 .
Swathi Beladakere Ramaswamy, Shivangi Singh, Sara Hooshmand, Cho Junsang, Megan Sweeney & Raghav Govindarajan. (2021) Current and Upcoming Treatment Modalities in Myasthenia Gravis. Journal of Clinical Neuromuscular Disease 23:2, pages 75-99.
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Jie Lin, Binbin Xue, Ruofan Zhu, Juyuan Pan, Jia Li, Yan Lin, Xiang Li & Junhui Xia. (2021) Intravenous immunoglobulin as the rescue treatment in NMOSD patients. Neurological Sciences 42:9, pages 3857-3863.
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Shengyao Su, Qing Liu, Xueping Zhang, Xinmei Wen, Lin Lei, Faxiu Shen, Zhirong Fan, Jianying Duo, Yan Lu, Li Di, Min Wang, Hai Chen, Wenjia Zhu, Min Xu, Suobin Wang & Yuwei Da. (2021) VNTR2/VNTR3 genotype in the FCGRT gene is associated with reduced effectiveness of intravenous immunoglobulin in patients with myasthenia gravis . Therapeutic Advances in Neurological Disorders 14, pages 175628642098674.
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Peter Manu, Liliana M. Rogozea & Corina Roman-Filip. (2021) Pharmacological Management of Myasthenia Gravis: A Century of Expert Opinions in Cecil Textbook of Medicine. American Journal of Therapeutics 28:6, pages e631-e637.
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Gabriela Riemekasten, Frank Petersen & Harald Heidecke. (2020) What Makes Antibodies Against G Protein-Coupled Receptors so Special? A Novel Concept to Understand Chronic Diseases. Frontiers in Immunology 11.
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Ali Aamer Habib, Ghazaleh Ahmadi Jazi & Tahseen Mozaffar. (2020) Update on immune‐mediated therapies for myasthenia gravis. Muscle & Nerve 62:5, pages 579-592.
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Laura Díez-Porras, Christian Homedes, Maria Antonia Alberti, Valentina Vélez-Santamaría & Carlos Casasnovas. (2020) Intravenous immunoglobulins may prevent prednisone-exacerbation in myasthenia gravis. Scientific Reports 10:1.
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Deepak Menon, Carolina Barnett & Vera Bril. (2020) Novel Treatments in Myasthenia Gravis. Frontiers in Neurology 11.
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Wenhua Xu, Mingshan Ren, Swagata Ghosh, Kai Qian, Zhaofeng Luo, Aimei Zhang, Cuiping Zhang & Jiajun Cui. (2020) Defects of CTLA-4 Are Associated with Regulatory T Cells in Myasthenia Gravis Implicated by Intravenous Immunoglobulin Therapy. Mediators of Inflammation 2020, pages 1-13.
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Bonnie J. B. Lewis, Jade Ville, Megan Blacquiere, Selena Cen, Rolf Spirig, Adrian W. Zuercher, Fabian Käsermann & Donald R. Branch. (2019) Using the K/BxN mouse model of endogenous, chronic, rheumatoid arthritis for the evaluation of potential immunoglobulin-based therapeutic agents, including IVIg and Fc-μTP-L309C, a recombinant IgG1 Fc hexamer. BMC Immunology 20:1.
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Waqar Waheed, Gretchen A. Ayer, Cindy L. Jadoo, Gary J. Badger, Marwa Aboukhatwa, Thomas H. BrannaganIIIIII & Rup Tandan. (2019) Safety of intravenous immune globulin in an outpatient setting for patients with neuromuscular disease. Muscle & Nerve 60:5, pages 528-537.
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Jonnathan Patiño, Diana Garzón, Tatiana Pacheco & Aldair Chaar. (2019) Recaída de miastenia gravis: ¿inmunoglobulina intravenosa como estrategia inicial en pacientes refractarios al tratamiento convencional?. Acta Colombiana de Cuidado Intensivo 19:2, pages 106-111.
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Adrian W. Zuercher, Mel Berger, Reinhard Bolli, Cédric Vonarburg, Martin Spycher, Amgad Shebl, Rolf Spirig, Christoph Kempf, Fabian Käsermann & Sylvia Miescher. 2019. Nijkamp and Parnham's Principles of Immunopharmacology. Nijkamp and Parnham's Principles of Immunopharmacology 327 368 .
Asaf Shemer, Shaye Kivity & Yehuda Shoenfeld. (2017) Clinical indications for intravenous immunoglobulin utilization in a tertiary medical center: a 9‐year retrospective study. Transfusion 58:2, pages 430-438.
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Paul Imbach. 2018. Antibody Therapy. Antibody Therapy 35 60 .
Aidan A. Levine, Todd D. Levine, Kathie Clarke & David Saperstein. (2017) Renal and hematologic side effects of long-term intravenous immunoglobulin therapy in patients with neurologic disorders. Muscle & Nerve 56:6, pages 1173-1176.
Crossref
P. R. Bourque, C. E. Pringle, W. Cameron, J. Cowan & J. Warman Chardon. (2016) Subcutaneous Immunoglobulin Therapy in the Chronic Management of Myasthenia Gravis: A Retrospective Cohort Study. PLOS ONE 11:8, pages e0159993.
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Jiří Piťha. (2016) Cardiac function in hypertensive patients with metabolic syndrome and microalbuminuria. Neurologie pro praxi 17:3, pages 95-99.
Crossref
Inga Koneczny, Pilar Martinez Martinez & Marc De Baets. 2016. Encyclopedia of Immunobiology. Encyclopedia of Immunobiology 168 179 .

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