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Review

Emerging biologics for the treatment of chronic rhinosinusitis

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Read on this site (4)

Jing Song, Ming Wang, Chengshuo Wang & Luo Zhang. (2023) Olfactory dysfunction in chronic rhinosinusitis: insights into the underlying mechanisms and treatments. Expert Review of Clinical Immunology 19:8, pages 993-1004.
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Maria De Filippo, Martina Votto, Amelia Licari, Fabio Pagella, Marco Benazzo, Giorgio Ciprandi & Gian Luigi Marseglia. (2021) Novel therapeutic approaches targeting endotypes of severe airway disease. Expert Review of Respiratory Medicine 15:10, pages 1303-1316.
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Quinn Thibodeaux, Mary Patricia Smith, Karen Ly, Kristen Beck, Wilson Liao & Tina Bhutani. (2019) A review of dupilumab in the treatment of atopic diseases. Human Vaccines & Immunotherapeutics 15:9, pages 2129-2139.
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Nsangou Ghogomu & Robert Kern. (2017) Chronic rhinosinusitis: the rationale for current treatments. Expert Review of Clinical Immunology 13:3, pages 259-270.
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Articles from other publishers (36)

Yasir Mehmood & Hira Shahid. (2023) Efficacy of intranasal fluticasone propionate nano nasal spray in management of chronic rhinitis: a randomized clinical trial. Italian Journal of Medicine.
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Na Cui, Xuewei Zhu, Chen Zhao, Cuida Meng, Jichao Sha & Dongdong Zhu. (2023) A Decade of Pathogenesis Advances in Non-Type 2 Inflammatory Endotypes in Chronic Rhinosinusitis: 2012–2022. International Archives of Allergy and Immunology 184:12, pages 1237-1253.
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Yasir Mehmood, Hira Shahid, Md Abdur Rashid, Yahya Alhamhoom & Mohsin Kazi. (2022) Developing of SiO2 Nanoshells Loaded with Fluticasone Propionate for Potential Nasal Drug Delivery: Determination of Pro-Inflammatory Cytokines through mRNA Expression. Journal of Functional Biomaterials 13:4, pages 229.
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Ramón Moreno-Luna, Ainhoa García-Lliberós de Miguel, Serafín Sánchez-Gómez & Alfonso del Cuvillo Bernal. 2022. Atlas of Frontal Sinus Surgery. Atlas of Frontal Sinus Surgery 317 327 .
Su-Jong Kim, Jee Won Moon & Heung-Man Lee. (2021) Update on Biologics in Treatment of Chronic Rhinosinusitis With Nasal Polyposis. Korean Journal of Otorhinolaryngology-Head and Neck Surgery 64:10, pages 693-702.
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Tim Delemarre, Bruce S. Bochner, Hans-Uwe Simon & Claus Bachert. (2021) Rethinking neutrophils and eosinophils in chronic rhinosinusitis. Journal of Allergy and Clinical Immunology 148:2, pages 327-335.
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Klimek L, Hagemann J, Casper I, Huppertz T, Bedbrook A & Bousquet J. (2021) Immunological background for treatments with biologicals in CRSwNP. Archives of Asthma, Allergy and Immunology 5:1, pages 022-029.
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Yun-Chu Chen, Sheryhan F. Gad, Dhawal Chobisa, Yongzhe Li & Yoon Yeo. (2021) Local drug delivery systems for inflammatory diseases: Status quo, challenges, and opportunities. Journal of Controlled Release 330, pages 438-460.
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Pauline Azzano, Élise Dufresne, Thomas Poder & Philippe Bégin. (2020) Economic considerations on the usage of biologics in the allergy clinic. Allergy 76:1, pages 191-209.
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Tim Delemarre, Gabriele Holtappels, Natalie De Ruyck, Nan Zhang, Hans Nauwynck, Claus Bachert & Elien Gevaert. (2021) A substantial neutrophilic inflammation as regular part of severe type 2 chronic rhinosinusitis with nasal polyps. Journal of Allergy and Clinical Immunology 147:1, pages 179-188.e2.
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Alan D. Workman & Benjamin S. Bleier. (2020) Biologic therapies versus surgical management for aspirin‐exacerbated respiratory disease: A review of preliminary data, efficacy, and cost. World Journal of Otorhinolaryngology - Head and Neck Surgery 6:4, pages 230-234.
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Tim Delemarre, Gabriele Holtappels, Natalie De Ruyck, Nan Zhang, Hans Nauwynck, Claus Bachert & Elien Gevaert. (2020) Type 2 inflammation in chronic rhinosinusitis without nasal polyps: Another relevant endotype. Journal of Allergy and Clinical Immunology 146:2, pages 337-343.e6.
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Melina S. Nasta, Vasileios A. Chatzinakis & Christos C. Georgalas. (2020) Updates on current evidence for biologics in chronic rhinosinusitis. Current Opinion in Otolaryngology & Head & Neck Surgery 28:1, pages 18-24.
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Abigail Walker, Carl Philpott & Claire Hopkins. (2019) What is the most appropriate treatment for chronic rhinosinusitis?. Postgraduate Medical Journal 95:1127, pages 493-496.
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Chengshuo Wang & Luo Zhang. (2019) Use of biologics in chronic sinusitis with nasal polyps. Current Opinion in Allergy & Clinical Immunology 19:4, pages 365-372.
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Karin Jonstam, Brian N. Swanson, Leda P. Mannent, Lars‐Olaf Cardell, Nian Tian, Ying Wang, Donghui Zhang, Chunpeng Fan, Gabriele Holtappels, Jennifer D. Hamilton, Annette Grabher, Neil M. H. Graham, Gianluca Pirozzi & Claus Bachert. (2019) Dupilumab reduces local type 2 pro‐inflammatory biomarkers in chronic rhinosinusitis with nasal polyposis. Allergy 74:4, pages 743-752.
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Kazuya Takeda, Shuhei Sakakibara, Kazuo Yamashita, Daisuke Motooka, Shota Nakamura, Marwa Ali El Hussien, Jun Katayama, Yohei Maeda, Masanobu Nakata, Shigeyuki Hamada, Daron M. Standley, Masaki Hayama, Takashi Shikina, Hidenori Inohara & Hitoshi Kikutani. (2019) Allergic conversion of protective mucosal immunity against nasal bacteria in patients with chronic rhinosinusitis with nasal polyposis. Journal of Allergy and Clinical Immunology 143:3, pages 1163-1175.e15.
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L. Klimek, M. Koennecke, J. Hagemann, B. Wollenberg & S. Becker. (2018) Immunologie der Polyposis nasi als Grundlage für eine Therapie mit BiologicalsImmunology of chronic rhinosinusitis with nasal polyps as a basis for treatment with biologicals. HNO 67:1, pages 15-26.
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Kristine A. Smith, Abigail Pulsipher, David A. Gabrielsen & Jeremiah A. Alt. (2018) Biologics in Chronic Rhinosinusitis: An Update and Thoughts for Future Directions. American Journal of Rhinology & Allergy 32:5, pages 412-423.
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Marlene M. Speth, Lloyd P. Hoehle, Katie M. Phillips, David S. Caradonna, Stacey T. Gray & Ahmad R. Sedaghat. (2018) Changes in chronic rhinosinusitis symptoms differentially associate with improvement in general health-related quality of life. Annals of Allergy, Asthma & Immunology 121:2, pages 195-199.
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Stephen Ball & Sean Carrie. (2018) What is the Current Place of Endonasal Frontal Sinus Surgery?. International Journal of Head and Neck Surgery 9:1, pages 21-25.
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Yao Yao, Shumin Xie, Chunguang Yang, Jianhui Zhang, Xuewen Wu & Hong Sun. (2017) Biomarkers in the evaluation and management of chronic rhinosinusitis with nasal polyposis. European Archives of Oto-Rhino-Laryngology 274:10, pages 3559-3566.
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Roxane Labrosse, François Graham, Anne Des Roches & Philippe Bégin. (2016) The Use of Omalizumab in Food Oral Immunotherapy. Archivum Immunologiae et Therapiae Experimentalis 65:3, pages 189-199.
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Don A. Bukstein & Allan T. Luskin. (2017) Pharmacoeconomics of Biologic Therapy. Immunology and Allergy Clinics of North America 37:2, pages 413-430.
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Javier Milara, Anselm Morell, Beatriz Ballester, Miguel Armengot, Esteban Morcillo & Julio Cortijo. (2017) MUC4 impairs the anti-inflammatory effects of corticosteroids in patients with chronic rhinosinusitis with nasal polyps. Journal of Allergy and Clinical Immunology 139:3, pages 855-862.e13.
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Y. S. Prakash, Andrew J. Halayko, Reinoud Gosens, Reynold A. PanettieriJr.Jr., Blanca Camoretti-Mercado & Raymond B. Penn. (2017) An Official American Thoracic Society Research Statement: Current Challenges Facing Research and Therapeutic Advances in Airway Remodeling. American Journal of Respiratory and Critical Care Medicine 195:2, pages e4-e19.
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Anudeep Kota, Deepak A. Deshpande, Mehra Haghi, Brian Oliver & Pawan Sharma. (2018) Autophagy and airway fibrosis: Is there a link?. F1000Research 6, pages 409.
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Anudeep Kota, Deepak A. Deshpande, Mehra Haghi, Brian Oliver & Pawan Sharma. (2017) Autophagy and airway fibrosis: Is there a link?. F1000Research 6, pages 409.
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Angela L. NoceraAna T. MeurerMarcel M. MiyakePeter M. SadowXue HanBenjamin S. Bleier. (2016) Secreted P‐glycoprotein is a noninvasive biomarker of chronic rhinosinusitis. The Laryngoscope 127:1.
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Katrin König, Christine Klemens, Mareike Haack, Marion San Nicoló, Sven Becker, Matthias F. Kramer & Moritz Gröger. (2016) Cytokine patterns in nasal secretion of non-atopic patients distinguish between chronic rhinosinusitis with or without nasal polys. Allergy, Asthma & Clinical Immunology 12:1.
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Y. S. Prakash. (2016) Emerging concepts in smooth muscle contributions to airway structure and function: implications for health and disease. American Journal of Physiology-Lung Cellular and Molecular Physiology 311:6, pages L1113-L1140.
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Diane Wang & Lisa A. Beck. (2016) Immunologic Targets in Atopic Dermatitis and Emerging Therapies: An Update. American Journal of Clinical Dermatology 17:5, pages 425-443.
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Steven K. Dennis, Kent Lam & Amber Luong. (2016) A Review of Classification Schemes for Chronic Rhinosinusitis with Nasal Polyposis Endotypes. Laryngoscope Investigative Otolaryngology 1:5, pages 130-134.
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Neha M. Dunn & Rohit K. Katial. (2016) Chronic Rhinosinusitis and Aspirin-Exacerbated Respiratory Disease. Immunology and Allergy Clinics of North America 36:3, pages 503-514.
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Christopher F. Thompson, Caroline P.E. Price, Julia He Huang, Jin-Young Min, Lydia A. Suh, Stephanie Shintani-Smith, David B. Conley, Robert P. Schleimer, Robert C. Kern & Bruce K. Tan. (2016) A pilot study of symptom profiles from a polyp vs an eosinophilic-based classification of chronic rhinosinusitis. International Forum of Allergy & Rhinology 6:5, pages 500-507.
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Rakesh K. Chandra, Matthew Clavenna, Madeleine Samuelson, S. Bobo Tanner & Justin H. Turner. (2016) Impact of omalizumab therapy on medication requirements for chronic rhinosinusitis. International Forum of Allergy & Rhinology 6:5, pages 472-477.
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