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The emerging role of carfilzomib combination therapy in the management of multiple myeloma

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Katelyn G. Ponder, Shannon M. Matulis, Sadae Hitosugi, Vikas A. Gupta, Cathy Sharp, Francis Burrows, Ajay K. Nooka, Jonathan L. Kaufman, Sagar Lonial & Lawrence H. Boise. (2016) Dual inhibition of Mcl-1 by the combination of carfilzomib and TG02 in multiple myeloma. Cancer Biology & Therapy 17:7, pages 769-777.
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Salvatore Pacifico, Valeria Ferretti, Valentina Albanese, Anna Fantinati, Eleonora Gallerani, Francesco Nicoli, Riccardo Gavioli, Francesco Zamberlan, Delia Preti & Mauro Marastoni. (2019) Synthesis and Biological Activity of Peptide α-Ketoamide Derivatives as Proteasome Inhibitors. ACS Medicinal Chemistry Letters 10:7, pages 1086-1092.
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Muhammad Arba, Andry Nur-Hidayat, Slamet Ibrahim Surantaadmaja & Daryono H. Tjahjono. (2018) Pharmacophore-based virtual screening for identifying β5 subunit inhibitor of 20S proteasome. Computational Biology and Chemistry 77, pages 64-71.
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Muhammad Arba, Andry Nur-Hidayat, Ruslin, Muhammad Yusuf, Sumarlin, Rukman Hertadi, Setyanto Tri Wahyudi, Slamet Ibrahim Surantaadmaja & Daryono H. Tjahjono. (2018) Molecular modeling on porphyrin derivatives as β5 subunit inhibitor of 20S proteasome. Computational Biology and Chemistry 74, pages 230-238.
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Emily E. Robinson & Regan J. Thomson. (2018) A Strategy for the Convergent and Stereoselective Assembly of Polycyclic Molecules. Journal of the American Chemical Society 140:5, pages 1956-1965.
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Carlos Roberto Koscky Paier, Sarah Sant'Anna Maranhão, Teiliane Rodrigues Carneiro, Lídia Moreira Lima, Danilo Damasceno Rocha, Renan da Silva Santos, Kaio Moraes de Farias, Manoel Odorico de Moraes-Filho & Claudia Pessoa. (2018) Natural products as new antimitotic compounds for anticancer drug development. Clinics 73, pages e813s.
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Philipp M. Cromm & Craig M. Crews. (2017) The Proteasome in Modern Drug Discovery: Second Life of a Highly Valuable Drug Target. ACS Central Science 3:8, pages 830-838.
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J. Ciavarri & S. Langston. 2017. Comprehensive Medicinal Chemistry III. Comprehensive Medicinal Chemistry III 95 112 .
Jonghoon Park, Eok Park, Cheol-Kyu Jung, Seung-Wan Kang, Byung Gyu Kim, Youngjoo Jung, Tae Hun Kim, Ji-Young Lim, Sung-Eun Lee, Chang-Ki Min & Kwang-Ai Won. (2016) Oral proteasome inhibitor with strong preclinical efficacy in myeloma models. BMC Cancer 16:1.
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A Keith Stewart. (2015) Carfilzomib for the treatment of patients with relapsed and/or refractory multiple myeloma. Future Oncology 11:15, pages 2121-2136.
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Beverly A. Teicher & Joseph E. Tomaszewski. (2015) Proteasome inhibitors. Biochemical Pharmacology 96:1, pages 1-9.
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Paul G Richardson, Philippe Moreau, Jacob P Laubach, Neeraj Gupta, Ai-Min Hui, Kenneth C Anderson, Jesús F San Miguel & Shaji Kumar. (2015) The investigational proteasome inhibitor ixazomib for the treatment of multiple myeloma. Future Oncology 11:8, pages 1153-1168.
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Lu Gao, Minjie Gao, Guang Yang, Yi Tao, Yuanyuan Kong, Ruixue Yang, Xiuqin Meng, Gongwen Ai, Rong Wei, Huiqun Wu, Xiaosong Wu & Jumei Shi. (2015) Synergistic Activity of Carfilzomib and Panobinostat in Multiple Myeloma Cells via Modulation of ROS Generation and ERK1/2. BioMed Research International 2015, pages 1-9.
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Philippe Moreau. (2014) Oral therapy for multiple myeloma: ixazomib arriving soon. Blood 124:7, pages 986-987.
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E.K. Mai & H. Goldschmidt. (2014) Klinik und Therapie des multiplen MyelomsClincal features and treatment of multiple myeloma. Der Radiologe 54:6, pages 538-544.
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Jeffrey A. Zonder. 2014. Resistance to Proteasome Inhibitors in Cancer. Resistance to Proteasome Inhibitors in Cancer 99 115 .

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