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Genome sequencing in myelodysplastic syndromes: can molecular mutations predict benefit from hypomethylating agent therapy?

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Russell Lewis, Jan Philipp Bewersdorf & Amer M Zeidan. (2021) Clinical Management of Anemia in Patients with Myelodysplastic Syndromes: An Update on Emerging Therapeutic Options. Cancer Management and Research 13, pages 645-657.
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Nora Chokr, Alexander B. Pine, Jan Philipp Bewersdorf, Rory M. Shallis, Maximilian Stahl & Amer M. Zeidan. (2019) Getting personal with myelodysplastic syndromes: is now the right time?. Expert Review of Hematology 12:4, pages 215-224.
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Amer M. Zeidan, Maximilian Stahl & Rami Komrokji. (2016) Emerging biological therapies for the treatment of myelodysplastic syndromes. Expert Opinion on Emerging Drugs 21:3, pages 283-300.
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Abdallah Abou Zahr, Ehab Saad Aldin, Lisa Barbarotta, Nikolai Podoltsev & Amer M Zeidan. (2015) The clinical use of DNA methyltransferase inhibitors in myelodysplastic syndromes. Expert Review of Anticancer Therapy 15:9, pages 1019-1036.
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Articles from other publishers (12)

Yu-Hung Wang, Chien-Chin Lin, Kristian Gurashi, Bettina Wingelhofer, Fabio M. R. Amaral, Chi-Yuan Yao, Hsin Ting Hsieh, Ming Chih Liu, Hsin-An Hou, Wen-Chien Chou, Kiran Batta, Daniel H. Wiseman & Hwei-Fang Tien. (2023) Higher MDMX expression was associated with hypomethylating agent resistance and inferior survival in MDS patients, inferring it a potential therapeutic target. Leukemia 37:12, pages 2507-2511.
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Susann Winter, Saeed Shoaie, Shahram Kordasti & Uwe Platzbecker. (2020) Integrating the “Immunome” in the Stratification of Myelodysplastic Syndromes and Future Clinical Trial Design. Journal of Clinical Oncology 38:15, pages 1723-1735.
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Anne Calleja, Seongseok Yun, Chimène Moreilhon, Jean Michel Karsenti, Lauris Gastaud, Lionel Mannone, Rami Komrokji, Najla Ali, Bérangère Dadone‐montaudie, Guillaume Robert, Patrick Auberger, Sophie Raynaud, David A. Sallman & Thomas Cluzeau. (2020) Clonal selection in therapy‐related myelodysplastic syndromes and acute myeloid leukemia under azacitidine treatment. European Journal of Haematology 104:5, pages 488-498.
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Guillermo F. Sanz, Mariam Ibañez & Esperanza Such. (2019) Do next-generation sequencing results drive diagnostic and therapeutic decisions in MDS?. Blood Advances 3:21, pages 3454-3460.
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Lucas H. Rifkin & Eric Y. Loo. (2019) Molecular Genetics in Myelodysplasia Outcomes Prognostication. Advances in Molecular Pathology 2:1, pages 35-43.
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Amer M. Zeidan, Rory M. Shallis, Rong Wang, Amy Davidoff & Xiaomei Ma. (2019) Epidemiology of myelodysplastic syndromes: Why characterizing the beast is a prerequisite to taming it. Blood Reviews 34, pages 1-15.
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Jiayu Huang, Huihui Zhao, Ming Hong, Han Zhu, Yu Zhu, Yun Lian, Shan Li, Jianyong Li & Sixuan Qian. (2018) Early recovery of the platelet count after decitabine-based induction chemotherapy is a prognostic marker of superior response in elderly patients with newly diagnosed acute myeloid leukaemia. BMC Cancer 18:1.
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Amer M. Zeidan, Maximilian Stahl, Mikkael A. Sekeres, David P. Steensma, Rami S. Komrokji & Steven D. Gore. (2017) A call for action: Increasing enrollment of untreated patients with higher-risk myelodysplastic syndromes in first-line clinical trials. Cancer 123:19, pages 3662-3672.
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James A. KennedyBenjamin L. Ebert. (2017) Clinical Implications of Genetic Mutations in Myelodysplastic Syndrome. Journal of Clinical Oncology 35:9, pages 968-974.
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A M Zeidan, M A Sekeres, G Garcia-Manero, D P Steensma, K Zell, J Barnard, N A Ali, C Zimmerman, G Roboz, A DeZern, A Nazha, E Jabbour, H Kantarjian, S D Gore, J P Maciejewski, A List & R Komrokji. (2015) Comparison of risk stratification tools in predicting outcomes of patients with higher-risk myelodysplastic syndromes treated with azanucleosides. Leukemia 30:3, pages 649-657.
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Amer M. Zeidan, Mikkael A. Sekeres, Xiao‐Feng Wang, Najla Al Ali, Guillermo Garcia‐Manero, David P. Steensma, Gail Roboz, John Barnard, Eric Padron, Amy DeZern, Jaroslaw P. Maciejewski, Alan F. List & Rami S. Komrokji. (2015) Comparing the prognostic value of risk stratifying models for patients with lower‐risk myelodysplastic syndromes: Is one model better?. American Journal of Hematology 90:11, pages 1036-1040.
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Aziz NazhaMikkael A. SekeresSteven D. Gore & Amer M. Zeidan. (2015) Molecular Testing in Myelodysplastic Syndromes for the Practicing Oncologist: Will the Progress Fulfill the Promise?. The Oncologist 20:9, pages 1069-1076.
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