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Expert Review of Gastroenterology & Hepatology Volume 1, 2007 - Issue 1
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Review

Familial pancreatic cancer: from genes to improved patient care

Ralph H Hruban Departments of Pathology and Oncology, The Sol Goldman Pancreatic Cancer Research Center, The Johns Hopkins Hospital, Weinberg Building 2242, 401 North Broadway, Baltimore, MD 21231,USA. [email protected]
,
Alison P Klein Departments of Pathology and Oncology, The Sol Goldman Pancreatic Cancer Research Center, 1550 Orleans Street, Room 303, Baltimore, MD 21231, USA. [email protected]
,
James R Eshleman Departments of Pathology and Oncology, The Sol Goldman Pancreatic Cancer Research Center, 1550 Orleans Street, Room 344, Baltimore, MD 21231, USA. [email protected]
,
Jennifer E Axilbund Research Associate, Department of Oncology, 600 North Wolfe Street, 550 Building, Suite 410, Baltimore, MD 21287, USA. [email protected]
&
Michael Goggins Departments of Pathology, Oncology and Medicine, The Sol Goldman Pancreatic Cancer Research Center, 1550 Orleans Street, Room 342, Baltimore, MD 21231, USA. [email protected]
Pages 81-88 | Published online: 10 Jan 2014

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Georg Feldmann, Collins Karikari, Marco dal Molin, Stephanie Duringer, Petra Volkmann, Detlef K. Bartsch, Savita Bisht, Jan-Bart Koorstra, Peter Brossart, Anirban Maitra & Volker Fendrich. (2011) Inactivation of Brca2 cooperates with Trp53R172H to induce invasive pancreatic ductal adenocarcinomas in mice. Cancer Biology & Therapy 11:11, pages 959-968.
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Nan Zhang, Xiao-juan Miao, Yan-rong Shuai, Hao Yao, Fang-Yi Fan & Yi-lan Liu. (2023) Family Aggregation of Hematological Malignancies Discovered from an Acute Myeloid Leukemia Patient with STK11 and THBD Gene Mutation. Case Reports in Oncology, pages 734-738.
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Mohamed Badheeb, Adham Abdelrahim, Abdullah Esmail, Godsfavour Umoru, Karen Abboud, Ebtesam Al-Najjar, Ghaith Rasheed, Mohammed Alkhulaifawi, Ala Abudayyeh & Maen Abdelrahim. (2022) Pancreatic Tumorigenesis: Precursors, Genetic Risk Factors and Screening. Current Oncology 29:11, pages 8693-8719.
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Manuel Gentiluomo, Federico Canzian, Andrea Nicolini, Federica Gemignani, Stefano Landi & Daniele Campa. (2022) Germline genetic variability in pancreatic cancer risk and prognosis. Seminars in Cancer Biology 79, pages 105-131.
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Kendra Flores, Kate Dinh, Erin Rouleau, Giles Whalen, Wahid Wassef & Jennifer LaFemina. (2015) Identification of genetic risk for pancreatic adenocarcinoma. Cancer Genetics 208:11, pages 559-563.
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Aikaterini Mastoraki, Victoria Chatzimavridou-Grigoriadou, Varvara Chatzipetrou, Sotiria Mastoraki, Ioannis S. Papanikolaou, Nikolaos Danias, Vasilios Smyrniotis & Nikolaos Arkadopoulos. (2014) Familial Pancreatic Cancer: Challenging Diagnostic Approach and Therapeutic Management. Journal of Gastrointestinal Cancer 45:3, pages 256-261.
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Wei Zou, Jianwen She & Vladimir Tolstikov. (2013) A Comprehensive Workflow of Mass Spectrometry-Based Untargeted Metabolomics in Cancer Metabolic Biomarker Discovery Using Human Plasma and Urine. Metabolites 3:3, pages 787-819.
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Yael Laitman, Liron Herskovitz, Talia Golan, Bella Kaufman, Shani Shimon Paluch & Eitan Friedman. (2012) The founder Ashkenazi Jewish mutations in the MSH2 and MSH6 genes in Israeli patients with gastric and pancreatic cancer. Familial Cancer 11:2, pages 243-247.
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C Romagosa, S Simonetti, L López-Vicente, A Mazo, M E Lleonart, J Castellvi & S Ramon y Cajal. (2011) p16Ink4a overexpression in cancer: a tumor suppressor gene associated with senescence and high-grade tumors. Oncogene 30:18, pages 2087-2097.
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Ang Li, Noriyuki Omura, Seung-Mo Hong, Audrey Vincent, Kimberly Walter, Margaret Griffith, Michael Borges & Michael Goggins. (2010) Pancreatic Cancers Epigenetically Silence SIP1 and Hypomethylate and Overexpress miR-200a/200b in Association with Elevated Circulating miR-200a and miR-200b Levels . Cancer Research 70:13, pages 5226-5237.
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Alan D. D'Andrea. (2010) Susceptibility Pathways in Fanconi's Anemia and Breast Cancer. New England Journal of Medicine 362:20, pages 1909-1919.
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Shiro Urayama, Wei Zou, Kindra Brooks & Vladimir Tolstikov. (2010) Comprehensive mass spectrometry based metabolic profiling of blood plasma reveals potent discriminatory classifiers of pancreatic cancer. Rapid Communications in Mass Spectrometry 24:5, pages 613-620.
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Aldo Scarpa, Paola Capelli & Ivana Cataldo. 2010. New Concepts in Diagnosis and Therapy of Pancreatic Adenocarcinoma. New Concepts in Diagnosis and Therapy of Pancreatic Adenocarcinoma 11 18 .
Alison P. Klein, Michael Borges, Margaret Griffith, Kieran Brune, Seung-Mo Hong, Noriyuki Omura, Ralph H. Hruban & Michael Goggins. (2009) Absence of Deleterious Palladin Mutations in Patients with Familial Pancreatic Cancer. Cancer Epidemiology, Biomarkers & Prevention 18:4, pages 1328-1330.
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Michael Goggins. 2008. Pancreatic Cancer. Pancreatic Cancer 229 252 .

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