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Advances in understanding of bile acid diarrhea

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Jun-Jie Hou, Xin Wang, Yu-Ming Wang & Bang-Mao Wang. (2022) Interplay between gut microbiota and bile acids in diarrhoea-predominant irritable bowel syndrome: a review. Critical Reviews in Microbiology 48:6, pages 696-713.
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Claudia Cirillo Sanchez, Wladzia Czuber-Dochan, Selena Cox, Trevor Murrells, Norton Christine & Muls Ann. (2021) Dietary Habits of Women with Gynecological Cancer before, during and after Treatment: A Long-Term Prospective Cohort Study. Nutrition and Cancer 73:11-12, pages 2643-2653.
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Lina Wang, Yan Zhou, Xiaohu Wang, Guangwen Zhang, Bin Guo, Xiaoming Hou, Juntao Ran, Qiuning Zhang, Chengcheng Li, Xueshan Zhao, Yichao Geng & Shuangwu Feng. (2020) Mechanism of Asbt (Slc10a2)-related bile acid malabsorption in diarrhea after pelvic radiation. International Journal of Radiation Biology 96:4, pages 510-519.
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Victor Chedid, Priya Vijayvargiya & Michael Camilleri. (2018) Elobixibat for the treatment of constipation. Expert Review of Gastroenterology & Hepatology 12:10, pages 951-960.
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Pamela J Hornby. (2015) Drug discovery approaches to irritable bowel syndrome. Expert Opinion on Drug Discovery 10:8, pages 809-824.
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Nelson Valentin, Andres Acosta & Michael Camilleri. (2015) Early investigational therapeutics for gastrointestinal motility disorders: from animal studies to Phase II trials. Expert Opinion on Investigational Drugs 24:6, pages 769-779.
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Articles from other publishers (65)

Hongmei Yin, Xia Gao, Hao Yang, Zhongkun Xu, Xuening Wang, Xuesong Wang, Yunjia Gao, Ziyi Shi, Xialin Chen, Liang Cao, Chenfeng Zhang, Zhenzhong Wang, Hanfei Hu & Wei Xiao. (2024) Total alditols from Cistanche deserticola attenuate functional constipation by regulating bile acid metabolism. Journal of Ethnopharmacology 320, pages 117420.
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Monika Lewinska, Martin Lund Kårhus, Anne-Marie Gade Ellegaard, Manuel Romero-Gómez, Rocio I R Macias, Jesper B Andersen & Filip Krag Knop. (2023) Serum lipidome unravels a diagnostic potential in bile acid diarrhoea. Gut 72:9, pages 1698-1708.
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Yosuke Saito & Toyoaki Sagae. (2023) Defecation status, intestinal microbiota, and habitual diet are associated with the fecal bile acid composition: a cross-sectional study in community-dwelling young participants. European Journal of Nutrition 62:5, pages 2015-2026.
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Liqing Du, Zhaozhou Zhang, Lixiang Zhai, Shujun Xu, Wei Yang, Chunhua Huang, Chengyuan Lin, Linda L. D. Zhong, Zhaoxiang Bian & Ling Zhao. (2023) Altered gut microbiota–host bile acid metabolism in IBS-D patients with liver depression and spleen deficiency pattern. Chinese Medicine 18:1.
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Kelly A. Fogelson, Pieter C. Dorrestein, Amir Zarrinpar & Rob Knight. (2023) The Gut Microbial Bile Acid Modulation and Its Relevance to Digestive Health and Diseases. Gastroenterology 164:7, pages 1069-1085.
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Shun-Mei Liu, Bruno Ifebi, Fred Johnson, Alison Xu, Jacquelin Ho, Yunlei Yang, Gary Schwartz, Young Hwan Jo & Streamson ChuaJr.Jr.. (2023) The gut signals to AGRP-expressing cells of the pituitary to control glucose homeostasis. Journal of Clinical Investigation 133:7.
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Tianxu Liu, Muyuan Ma, Kelei Li, Wei Tan, Han Yu & Ling Wang. (2023) Biomarkers for Bile Acid Malabsorption in Diarrhea-predominant Irritable Bowel Syndrome. Journal of Clinical Gastroenterology 57:5, pages 451-458.
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Zejing Zhao, Shumin Xu, Wangyang Zhang, Danjun Wu & Gensheng Yang. (2022) Probiotic Escherichia coli NISSLE 1917 for inflammatory bowel disease applications . Food & Function 13:11, pages 5914-5924.
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Yulia Shulpekova, Maria Zharkova, Pyotr Tkachenko, Igor Tikhonov, Alexander Stepanov, Alexandra Synitsyna, Alexander Izotov, Tatyana Butkova, Nadezhda Shulpekova, Natalia Lapina, Vladimir Nechaev, Svetlana Kardasheva, Alexey Okhlobystin & Vladimir Ivashkin. (2022) The Role of Bile Acids in the Human Body and in the Development of Diseases. Molecules 27:11, pages 3401.
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Muhammad Shahidul Islam, Anjiya Sharif, Nathania Kwan & Kam C. Tam. (2022) Bile Acid Sequestrants for Hypercholesterolemia Treatment Using Sustainable Biopolymers: Recent Advances and Future Perspectives. Molecular Pharmaceutics 19:5, pages 1248-1272.
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Kristine H. Allin, Manasi Agrawal, Aske T. Iversen, Jacob Antonsen, Marie Villumsen & Tine Jess. (2022) The Risk of Type 2 Diabetes in Patients With Inflammatory Bowel Disease After Bowel Resections: A Nationwide Cohort Study. Gastro Hep Advances 1:5, pages 777-784.
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Róisín Ní Dhonnabháín, Qiao Xiao & Dervla O’Malley. (2021) Aberrant Gut-To-Brain Signaling in Irritable Bowel Syndrome - The Role of Bile Acids. Frontiers in Endocrinology 12.
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Prapaporn Boonma, Jordan M. Shapiro, Emily B. Hollister, Shyam Badu, Qinglong Wu, Erica M. Weidler, Bincy P. Abraham, Sridevi Devaraj, Ruth Ann Luna, James Versalovic, Margaret M. Heitkemper, Tor C. Savidge & Robert J. Shulman. (2021) Probiotic VSL#3 Treatment Reduces Colonic Permeability and Abdominal Pain Symptoms in Patients With Irritable Bowel Syndrome. Frontiers in Pain Research 2.
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Raquel Rocha, Geisa de J Santos & Genoile Santana. (2021) Influence of nutritional status in the postoperative period of patients with inflammatory bowel disease. World Journal of Gastrointestinal Pharmacology and Therapeutics 12:5, pages 90-99.
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Jiayu Ye, Lauren A. E. Erland, Sandeep K. Gill, Stephanie L. Bishop, Andrea Verdugo-Meza, Susan J. Murch & Deanna L. Gibson. (2021) Metabolomics-Guided Hypothesis Generation for Mechanisms of Intestinal Protection by Live Biotherapeutic Products. Biomolecules 11:5, pages 738.
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L. Кh. Indeykina, Е. А. Sabelnikova, G. G. Varvanina, S. U. Silvestrova, А. V. Smirnova, L. М. Krums, A. A. Viaznikova & А. I. Parfenov. (2021) The role of fibroblast growth factor 19 in pathogenesis of bile acid diarrhea of the patients who underwent cholecystectomy. Terapevticheskii arkhiv 93:2, pages 174-178.
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Christine Wu, Maria‐Elisabeth Smet, Susan Heath, Jennifer Curnow, Ming‐Wei Lin, Jacob George & Thushari I. Alahakoon. (2020) Pregnancy complicated by refractory severe hypercholanaemia from sodium taurocholate co‐transporting polypeptide deficiency. Journal of Obstetrics and Gynaecology Research 47:2, pages 822-826.
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Lauren E Hughes, Clare Ford, Matthew J Brookes & Rousseau Gama. (2020) Bile acid diarrhoea: Current and potential methods of diagnosis. Annals of Clinical Biochemistry: International Journal of Laboratory Medicine 58:1, pages 22-28.
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Lehar Khanna & Michael Camilleri. (2020) Review article: Elobixibat: a novel treatment for chronic constipation. Alimentary Pharmacology & Therapeutics 53:2, pages 234-242.
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Eamonn M.M. Quigley. (2021) The patient with irritable bowel syndrome-type symptoms: when to investigate and how?. Current Opinion in Gastroenterology 37:1, pages 39-43.
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Eamonn M. M. Quigley & Vineet Gudsoorkar. 2021. Geriatric Gastroenterology. Geriatric Gastroenterology 1645 1654 .
Taiki Aoyama, Akira Fukumoto, Kenjiro Shigita, Naoki Asayama, Shinichi Mukai & Shinji Nagata. (2020) Bile pigment in small-bowel water content may reflect bowel habits: a retrospective analysis of a capsule endoscopy imaging series. BMC Gastroenterology 20:1.
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Olga Kiss, Jekaterina Maizik, Kadri Tamme, Aivar Orav, Marcel C.G. van de Poll & Annika Reintam Blaser. (2020) Diarrhea and elevation of plasma markers of cholestasis are common and often occur concomitantly in critically ill patients. Journal of Critical Care 60, pages 120-126.
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Amanda B. Blake, Annalis Cigarroa, Hannah L. Klein, Mohammad R. Khattab, Theresa Keating, Patti Van De Coevering, Jonathan A. Lidbury, Jörg M. Steiner & Jan S. Suchodolski. (2020) Developmental stages in microbiota, bile acids, and clostridial species in healthy puppies. Journal of Veterinary Internal Medicine 34:6, pages 2345-2356.
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Ann Muls, Alexandra Taylor, Susan Lalondrelle, Mohammed Kabir, Christine Norton, Ailsa Hart & H. Jervoise Andreyev. (2020) A proposed tailored investigational algorithm for women treated for gynaecological cancer with long-term gastrointestinal consequences. Supportive Care in Cancer 28:10, pages 4881-4889.
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Michael Camilleri, Sara Linker Nord, Duane Burton, Ibironke Oduyebo, Yiming Zhang, Jin Chen, Koeun Im, Prafulla Bhad, Michael K. Badman, David S. Sanders & Julian R. F. Walters. (2020) Randomised clinical trial: significant biochemical and colonic transit effects of the farnesoid X receptor agonist tropifexor in patients with primary bile acid diarrhoea. Alimentary Pharmacology & Therapeutics 52:5, pages 808-820.
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Ruben A.T. Mars, Yi Yang, Tonya Ward, Mo Houtti, Sambhawa Priya, Heather R. Lekatz, Xiaojia Tang, Zhifu Sun, Krishna R. Kalari, Tal Korem, Yogesh Bhattarai, Tenghao Zheng, Noam Bar, Gary Frost, Abigail J. Johnson, Will van Treuren, Shuo Han, Tamas Ordog, Madhusudan Grover, Justin Sonnenburg, Mauro D’Amato, Michael Camilleri, Eran Elinav, Eran Segal, Ran Blekhman, Gianrico Farrugia, Jonathan R. Swann, Dan Knights & Purna C. Kashyap. (2020) Longitudinal Multi-omics Reveals Subset-Specific Mechanisms Underlying Irritable Bowel Syndrome. Cell 182:6, pages 1460-1473.e17.
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A. S. Sarsenbaevа & L. B. Lazebnik. (2020) Diarrhea in adults. Clinical guidelines. Project. Experimental and Clinical Gastroenterology:6, pages 4-41.
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Frederik Dethloff, Fernando Vargas, Emmanuel Elijah, Robert Quinn, Dong Ik Park, David P. Herzog, Marianne B. Müller, Emily C. Gentry, Rob Knight, Antonio Gonzalez, Pieter C. Dorrestein & Christoph W. Turck. (2020) Paroxetine Administration Affects Microbiota and Bile Acid Levels in Mice. Frontiers in Psychiatry 11.
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M. Masudur Rahman & Uday C. Ghoshal. 2020. Clinical and Basic Neurogastroenterology and Motility. Clinical and Basic Neurogastroenterology and Motility 477 491 .
Eamonn M. M. Quigley & Vineet Gudsoorkar. 2019. Geriatric Gastroenterology. Geriatric Gastroenterology 1 10 .
Ling Zhao, Wei Yang, Yang Chen, Fengjie Huang, Lin Lu, Chengyuan Lin, Tao Huang, Ziwan Ning, Lixiang Zhai, Linda L.D. Zhong, Waiching Lam, Zhen Yang, Xuan Zhang, Chungwah Cheng, Lijuan Han, Qinwei Qiu, Xiaoxiao Shang, Runyue Huang, Haitao Xiao, Zhenxing Ren, Dongfeng Chen, Silong Sun, Hani El-Nezami, Zongwei Cai, Aiping Lu, Xiaodong Fang, Wei Jia & Zhaoxiang Bian. (2019) A Clostridia-rich microbiota enhances bile acid excretion in diarrhea-predominant irritable bowel syndrome. Journal of Clinical Investigation 130:1, pages 438-450.
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Tianying Duan, Onur Cil, C. Ming Tse, Rafiquel Sarker, Ruxian Lin, Mark Donowitz & Alan S. Verkman. (2019) Inhibition of CFTR‐mediated intestinal chloride secretion as potential therapy for bile acid diarrhea. The FASEB Journal 33:10, pages 10924-10934.
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A. Baena García, F. Partida Palma, S. García Martínez, M. de Bonilla Candau & M. Pajares Vinardell. (2019) 75Se-Homocholic acid taurine scintigraphy (75SeHCAT®), a standard benchmark test in bile acid malabsorption?. Revista Española de Medicina Nuclear e Imagen Molecular (English Edition) 38:5, pages 305-311.
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A. Baena García, F. Partida Palma, S. García Martínez, M. de Bonilla Candau & M. Pajares Vinardell. (2019) Gammagrafía con 75Se-ácido tauroselcólico (75SeHCAT®), ¿prueba de referencia en la malabsorción de ácidos biliares?. Revista Española de Medicina Nuclear e Imagen Molecular 38:5, pages 305-311.
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Benjamin I. Brown. (2019) Does Irritable Bowel Syndrome Exist? Identifiable and Treatable Causes of Associated Symptoms Suggest It May Not. Gastrointestinal Disorders 1:3, pages 314-340.
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Ivo P. van de Peppel, Frank A.J.A. Bodewes, Henkjan J. Verkade & Johan W. Jonker. (2019) Bile acid homeostasis in gastrointestinal and metabolic complications of cystic fibrosis. Journal of Cystic Fibrosis 18:3, pages 313-320.
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Thomas Skouras, Susanna Dodd, Yash Prasad, Joseph Rassam, Nazreen Morley & Sreedhar Subramanian. (2018) Brief report: length of ileal resection correlates with severity of bile acid malabsorption in Crohn’s disease. International Journal of Colorectal Disease 34:1, pages 185-188.
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Yuji Kumagai, Hideki Amano, Yoshinobu Sasaki, Chie Nakagawa, Mika Maeda, Ichiro Oikawa & Hidetoshi Furuie. (2018) Effect of single and multiple doses of elobixibat, an ileal bile acid transporter inhibitor, on chronic constipation: A randomized controlled trial. British Journal of Clinical Pharmacology 84:10, pages 2393-2404.
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Ramesh P Arasaradnam, Steven Brown, Alastair Forbes, Mark R Fox, Pali Hungin, Lawrence Kelman, Giles Major, Michelle O’Connor, Dave S Sanders, Rakesh Sinha, Stephen Charles Smith, Paul Thomas & Julian R F Walters. (2018) Guidelines for the investigation of chronic diarrhoea in adults: British Society of Gastroenterology, 3rd edition. Gut 67:8, pages 1380-1399.
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Luisa M.� Mena Bares, José M. Benítez Cantero, Eva Iglesias Flores, Beatriz Gros Alcalde, Estefanía Moreno Ortega, Francisco R. Maza Muret, Elvira Carmona Asenjo, M.� Valle García Sánchez & Juan A. Vallejo Casas. (2018) Bile acid malabsorption in patients with chronic diarrhea and Crohn�s disease. Revista Española de Enfermedades Digestivas 111.
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Zhenyang Ge, Zhijun Duan, Hang Yang, Shengai Zhang, Shuang Zhang, Lixia Wang, Dong Yang, Xiaoyu Sun, Zhifeng Zhang, Liping Su, Hong Zhu, Dongdong Zhou, Bojia Liu, Honggang Shi, Jun Yu, Hui Yang, Qingyong Chang, Nina Zhang, Dongsheng Wu & Jiande D. Z. Chen. (2018) Home-Based Transcutaneous Neuromodulation Improved Constipation via Modulating Gastrointestinal Hormones and Bile Acids. Evidence-Based Complementary and Alternative Medicine 2018, pages 1-12.
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C. Borup, S. Wildt, J. J. Rumessen, P. N. Bouchelouche, J. Graff, M. Damgaard, C. McQuitty, D. Rainteau & L. K. Munck. (2017) Chenodeoxycholic acid stimulated fibroblast growth factor 19 response – a potential biochemical test for bile acid diarrhoea.. Alimentary Pharmacology & Therapeutics 45:11, pages 1433-1442.
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Lawrence R. Schiller. (2017) Antidiarrheal Drug Therapy. Current Gastroenterology Reports 19:5.
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L.M. Mena Bares, E. Carmona Asenjo, M.V. García Sánchez, E. Moreno Ortega, F.R. Maza Muret, M.V. Guiote Moreno, A.M. Santos Bueno, E. Iglesias Flores, J.M. Benítez Cantero & J.A. Vallejo Casas. (2017) 75SeHCAT scan in bile acid malabsorption in chronic diarrhea. Revista Española de Medicina Nuclear e Imagen Molecular (English Edition) 36:1, pages 37-47.
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L.M. Mena Bares, E. Carmona Asenjo, M.V. García Sánchez, E. Moreno Ortega, F.R. Maza Muret, M.V. Guiote Moreno, A.M. Santos Bueno, E. Iglesias Flores, J.M. Benítez Cantero & J.A. Vallejo Casas. (2017) Gammagrafía con 75SeHCAT en la diarrea crónica por malabsorción de ácidos biliares. Revista Española de Medicina Nuclear e Imagen Molecular 36:1, pages 37-47.
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Michael Camilleri & Gregory J. Gores. (2015) Therapeutic targeting of bile acids. American Journal of Physiology-Gastrointestinal and Liver Physiology 309:4, pages G209-G215.
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