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Glutamatergic agents for schizophrenia: current evidence and perspectives

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Sheng-Min Wang, Changsu Han, Soo-Jung Lee, Tae-Youn Jun, Ashwin A. Patkar, Prakash S. Masand & Chi-Un Pae. (2017) Investigational dopamine antagonists for the treatment of schizophrenia. Expert Opinion on Investigational Drugs 26:6, pages 687-698.
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Naista Zhand, David G. Attwood & Philip D. Harvey. (2019) Glutamate modulators for treatment of schizophrenia. Personalized Medicine in Psychiatry 15-16, pages 1-12.
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Mitul A. Mehta, Anne Schmechtig, Vasileia Kotoula, Juliet McColm, Kimberley Jackson, Claire Brittain, Sitra Tauscher-Wisniewski, Bruce J. Kinon, Paul D. Morrison, Thomas Pollak, Timothy Mant, Steven C. R. Williams & Adam J. Schwarz. (2018) Group II metabotropic glutamate receptor agonist prodrugs LY2979165 and LY2140023 attenuate the functional imaging response to ketamine in healthy subjects. Psychopharmacology 235:7, pages 1875-1886.
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Eva Drazanova, Jana Ruda-Kucerova, Lucie Kratka, Katerina Horska, Regina Demlova, Zenon StarcukJr.Jr. & Tomas Kasparek. (2018) Poly(I:C) model of schizophrenia in rats induces sex-dependent functional brain changes detected by MRI that are not reversed by aripiprazole treatment. Brain Research Bulletin 137, pages 146-155.
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Zhemeng Wu, Zhigang Yang, Mengjiao Zhang, Xiaohan Bao, Fang Han & Liang Li. (2018) The role of N-methyl-d-aspartate receptors and metabotropic glutamate receptor 5 in the prepulse inhibition paradigms for studying schizophrenia: pharmacology, neurodevelopment, and genetics. Behavioural Pharmacology 29:1, pages 13-27.
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Marco Solmi, Nicola Veronese, Nita Thapa, Silvia Facchini, Brendon Stubbs, Michele Fornaro, André F. Carvalho & Christoph U. Correll. (2017) Systematic review and meta-analysis of the efficacy and safety of minocycline in schizophrenia. CNS Spectrums 22:5, pages 415-426.
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Amir A. Sepehry, Michael Sarai & Ging-Yuek R. Hsiung. (2017) Pharmacological Therapy for Apathy in Alzheimer’s Disease: A Systematic Review and Meta-Analysis. Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 44:3, pages 267-275.
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Minela Hadzic, Alexander Jack & Petra Wahle. (2017) Ionotropic glutamate receptors: Which ones, when, and where in the mammalian neocortex. Journal of Comparative Neurology 525:4, pages 976-1033.
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Gary Remington, George Foussias, Gagan Fervaha, Ofer Agid, Hiroyoshi Takeuchi, Jimmy Lee & Margaret Hahn. (2016) Treating Negative Symptoms in Schizophrenia: an Update. Current Treatment Options in Psychiatry 3:2, pages 133-150.
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Savita G. Bhakta, Hsun-Hua Chou, Brinda Rana, Jo A. Talledo, Bryan Balvaneda, Laura Gaddis, Gregory A. Light & Neal R. Swerdlow. (2016) Effects of acute memantine administration on MATRICS Consensus Cognitive Battery performance in psychosis: Testing an experimental medicine strategy. Psychopharmacology 233:12, pages 2399-2410.
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Byung Dae Lee, Je Min Park, Young Min Lee, Eunsoo Moon, Hee Jeong Jeong, Young In Chung & Young Mi Yi. (2016) Heritability and Familiality of Temperament and Character Dimensions in Korean Families with Schizophrenic Linkage Disequilibrium. Clinical Psychopharmacology and Neuroscience 14:2, pages 203-209.
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Annette B. Brühl & Barbara J. Sahakian. (2016) Drugs, games, and devices for enhancing cognition: implications for work and society. Annals of the New York Academy of Sciences 1369:1, pages 195-217.
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Mathias Zink & Susanne Englisch. (2016) Schizophrenia treatment: an obstacle course. The Lancet Psychiatry 3:4, pages 310-312.
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Scott O. LilienfeldMichael T. Treadway. (2016) Clashing Diagnostic Approaches: DSM-ICD Versus RDoC. Annual Review of Clinical Psychology 12:1, pages 435-463.
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Joseph Gonzalez-Heydrich, Michelle Bosquet Enlow, Eugene D’Angelo, Larry J. Seidman, Sarah Gumlak, April Kim, Kristen A. Woodberry, Ashley Rober, Sahil Tembulkar, Kyle O’Donnell, Hesham M. Hamoda, Kara Kimball, Alexander Rotenberg, Lindsay M. Oberman, Alvaro Pascual-Leone, Matcheri S. Keshavan & Frank H. Duffy. (2016) N100 Repetition Suppression Indexes Neuroplastic Defects in Clinical High Risk and Psychotic Youth. Neural Plasticity 2016, pages 1-11.
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Chieh-Hsin Lin, Pei-Pei Lin, Chun-Yuan Lin, Ching-Hua Lin, Chiung-Hsien Huang, Yu-Jhen Huang & Hsien-Yuan Lane. (2016) Decreased mRNA expression for the two subunits of system xc−, SLC3A2 and SLC7A11, in WBC in patients with schizophrenia: Evidence in support of the hypo-glutamatergic hypothesis of schizophrenia. Journal of Psychiatric Research 72, pages 58-63.
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Matteo Cella, Clare Reeder & Til Wykes. (2015) Cognitive remediation in schizophrenia—now it is really getting personal. Current Opinion in Behavioral Sciences 4, pages 147-151.
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