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Review

Long-acting muscarinic antagonists

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Read on this site (5)

Radivoj Arezina, Tao Chen & Duolao Wang. (2023) Conventional, Complementary and Alternative Medicines: Mechanistic Insights into Therapeutic Landscape of Chronic Obstructive Pulmonary Disease. International Journal of Chronic Obstructive Pulmonary Disease 18, pages 447-457.
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James F Donohue, Donald A Mahler & Sanjay Sethi. (2019) Revefenacin: A Once-Daily, Long-Acting Bronchodilator For Nebulized Treatment Of COPD. International Journal of Chronic Obstructive Pulmonary Disease 14, pages 2947-2958.
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Mario Malerba, Alessandro Radaeli, Giuseppe Santini, Jaymin Morjaria, Nadia Mores, Chiara Mondino, Giuseppe Macis & Paolo Montuschi. (2018) The discovery and development of aclidinium bromide for the treatment of chronic obstructive pulmonary disease. Expert Opinion on Drug Discovery 13:6, pages 563-577.
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Andrea S. Melani & Piersante Sestini. (2016) Safety of long acting muscarinic antagonists: are all these drugs always and equally safe?. Current Medical Research and Opinion 32:5, pages 975-977.
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Articles from other publishers (33)

Chengqian Zhang, Davide D'Angelo, Francesca Buttini & Mingshi Yang. (2023) Long-acting inhaled medicines: Present and future. Advanced Drug Delivery Reviews, pages 115146.
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Clarissa GobettiSanjeeva Dissanayake, Jag ShurWilliam GanleyLucas SilvaIsam SalemOmaima NajibUsama Harb. (2023) Bioequivalence of Two Tiotropium Dry Powder Inhalers and the Utility of Realistic Impactor Testing. Journal of Aerosol Medicine and Pulmonary Drug Delivery 36:5, pages 257-267.
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Khizar S Khan, Sanyah Jawaid, Unaib Ahmed Memon, Tharindu Perera, Usman Khan, Umm E Farwa, Urmi Jindal, Muhammad Sohaib Afzal, Waleed Razzaq, Zain U Abdin & Uzzam Ahmed Khawaja. (2023) Management of Chronic Obstructive Pulmonary Disease (COPD) Exacerbations in Hospitalized Patients From Admission to Discharge: A Comprehensive Review of Therapeutic Interventions. Cureus.
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Zsolt Cselényi, Aurelija Jucaite, Pär Ewing, Per Stenkrona, Cecilia Kristensson, Peter Johnström, Magnus Schou, Martin Bolin, Christer Halldin, Bengt Larsson, Ken Grime, Ulf G Eriksson & Lars Farde. (2023) Proof of lung muscarinic receptor occupancy by tiotropium: Translational Positron Emission Tomography studies in non-human primates and humans. Frontiers in Nuclear Medicine 2.
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Bryan J. Mathis, Misa Kusumoto, Alexander Zaboronok & Yuji Hiramatsu. (2021) Packaging and Delivery of Asthma Therapeutics. Pharmaceutics 14:1, pages 92.
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Chuchu Zhang, Meng Zhang, Yalei Wang, Huaiyu Xiong, Qiangru Huang, Tiankui Shuai & Jian Liu. (2023) Efficacy and Cardiovascular Safety of LAMA in Patients with COPD: A Systematic Review and Meta-Analysis. Journal of Investigative Medicine 69:8, pages 1391-1398.
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Jiaxing Zhang, Yihong Xie, Joey Sum-wing Kwong, Long Ge, Rui He, Wenyi Zheng, Jing Han, Rui Zhang, Huaye Zhao, Yuru He & Xiaosi Li. (2021) The Efficacy and Safety of Revefenacin for the Treatment of Chronic Obstructive Pulmonary Disease: A Systematic Review. Frontiers in Pharmacology 12.
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Lveli Wang, Chuang Xiao, Yaping Liang, Zhiying Weng & Weimin Yang. (2021) Research Advances in COPD Drugs and Novel Targets. Nano LIFE 11:03, pages 2140008.
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Zhu Luo, Chao Hu, Yuanyuan Pan, Jia Miao, Ying Wang, Li Ding & Maozhi Liang. (2021) Safety, Tolerability and Pharmacokinetics of Bencycloquidium Bromide, a Novel Inhaled Anticholinergic Bronchodilator, in Healthy Subjects: Results from Phase I Studies. European Journal of Pharmaceutical Sciences 157, pages 105646.
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Parthasarathi Bhattacharyya, Dipanjan Saha, Sayoni Sengupta & Debkanya De. (2021) Feasibility of testing bronchodilator responsiveness with glycopyrronium in obstructive airway diseases: the initial appraisal of the pilot experience. The Journal of Association of Chest Physicians 9:1, pages 16.
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Maher Khdour, Hussein Hallak & Hani Abdeen. 2021. Handbook of Healthcare in the Arab World. Handbook of Healthcare in the Arab World 2807 2826 .
Akira Koarai, Hisatoshi Sugiura, Mitsuhiro Yamada, Tomohiro Ichikawa, Naoya Fujino, Tomotaka Kawayama & Masakazu Ichinose. (2020) Treatment with LABA versus LAMA for stable COPD: a systematic review and meta-analysis. BMC Pulmonary Medicine 20:1.
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Yoshiaki Minakata & Seigo Sasaki. (2020) Data Reproducibility and Effectiveness of Bronchodilators for Improving Physical Activity in COPD Patients. Journal of Clinical Medicine 9:11, pages 3497.
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David Moore. (2020) Management of COPD exacerbations: pharmacotherapeutics of medications. Journal of Prescribing Practice 2:8, pages 450-458.
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Anees ur Rehman, Mohamed Azmi Ahmad Hassali, Sameen Abbas, Irfhan Ali Bin Hyder Ali, Sabariah Noor Harun, Jaya Muneswarao & Rabia Hussain. (2019) Pharmacological and non-pharmacological management of COPD; limitations and future prospects: a review of current literature. Journal of Public Health 28:4, pages 357-366.
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David Moore. (2020) Management of COPD exacerbations: pharmacotherapeutics of medications. British Journal of Nursing 29:13, pages 738-743.
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Kaiser Jehan Peerzada. 2020. Chronic Lung Diseases. Chronic Lung Diseases 157 180 .
Yong Suk Jo & Yong Bum Park. (2019) Pharmacotherapy for chronic obstructive pulmonary disease. Journal of the Korean Medical Association 62:5, pages 277.
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Maher Khdour, Hussein Hallak & Hani Abdeen. 2019. Handbook of Healthcare in the Arab World. Handbook of Healthcare in the Arab World 1 21 .
Jennifer Padden Elliott, Nicole Sossong, Deborah Gentile, Kacie M. Kidd, David P. Skoner, Christina E. Conte & Jonathan D. Skoner. 2019. Allergy and Asthma. Allergy and Asthma 873 907 .
Han-Rong Feng, Chao Zhang & Song-Min Ying. (2018) Classical and Emerging Therapies against Chronic Obstructive Pulmonary Disease. Chinese Medical Journal 131:16, pages 1894-1897.
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Yuanzhi Wang, Ping Cui, Jingjing Liu, Hongxia Wu & Jun Ma. (2018) Aclidinium bromide inhibits the growth and metastasis of gastric cancer MKN‑28 cells via the PI3K signaling pathway. Molecular Medicine Reports.
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Sharath S. Hegde, M. Teresa Pulido-Rios, Mark A. Luttmann, James J. Foley, Gerald E. Hunsberger, Tod Steinfeld, TaeWeon Lee, Yuhua Ji, Mathai M. Mammen & Jeffrey R. Jasper. (2018) Pharmacological properties of revefenacin (TD-4208), a novel, nebulized long-acting, and lung selective muscarinic antagonist, at human recombinant muscarinic receptors and in rat, guinea pig, and human isolated airway tissues. Pharmacology Research & Perspectives 6:3, pages e00400.
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Dean Quinn, Christopher N. Barnes, Wayne Yates, David L. Bourdet, Edmund J. Moran, Peter Potgieter, Andrew Nicholls, Brett Haumann & Dave Singh. (2018) Pharmacodynamics, pharmacokinetics and safety of revefenacin (TD-4208), a long-acting muscarinic antagonist, in patients with chronic obstructive pulmonary disease (COPD): Results of two randomized, double-blind, phase 2 studies. Pulmonary Pharmacology & Therapeutics 48, pages 71-79.
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Jennifer Padden Elliott, Nicole Sossong, Deborah Gentile, Kacie M. Kidd, Christina E. Conte, Jonathan D. Skoner & David P. Skoner. 2018. Allergy and Asthma. Allergy and Asthma 1 35 .
Salvatore Corrao, Giuseppe Brunori, Umberto Lupo & Francesco Perticone. (2017) Effectiveness and safety of concurrent beta-blockers and inhaled bronchodilators in COPD with cardiovascular comorbidities. European Respiratory Review 26:145, pages 160123.
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Claus F. Vogelmeier, Gerard J. Criner, Fernando J. Martinez, Antonio Anzueto, Peter J. Barnes, Jean Bourbeau, Bartolome R. Celli, Rongchang Chen, Marc Decramer, Leonardo M. Fabbri, Peter Frith, David M.G. Halpin, M. Victorina López Varela, Masaharu Nishimura, Nicolas Roche, Roberto Rodriguez‐Roisin, Don D. Sin, Dave Singh, Robert Stockley, Jørgen Vestbo, Jadwiga A. Wedzicha & Alvar Agusti. (2017) Global Strategy for the Diagnosis, Management and Prevention of Chronic Obstructive Lung Disease 2017 Report. Respirology 22:3, pages 575-601.
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Claus F. Vogelmeier, Gerard J. Criner, Fernando J. Martinez, Antonio Anzueto, Peter J. Barnes, Jean Bourbeau, Bartolome R. Celli, Rongchang Chen, Marc Decramer, Leonardo M. Fabbri, Peter Frith, David M.G. Halpin, M. Victorina López Varela, Masaharu Nishimura, Nicolas Roche, Roberto Rodriguez-Roisin, Don D. Sin, Dave Singh, Robert Stockley, Jørgen Vestbo, Jadwiga A. Wedzicha & Alvar Agusti. (2017) Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Lung Disease 2017 Report: GOLD Executive Summary. European Respiratory Journal 49:3, pages 1700214.
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Claus F. Vogelmeier, Gerard J. Criner, Fernando J. Martinez, Antonio Anzueto, Peter J. Barnes, Jean Bourbeau, Bartolome R. Celli, Rongchang Chen, Marc Decramer, Leonardo M. Fabbri, Peter Frith, David M. G. Halpin, M. Victorina López Varela, Masaharu Nishimura, Nicolas Roche, Roberto Rodriguez-Roisin, Don D. Sin, Dave Singh, Robert Stockley, Jørgen Vestbo, Jadwiga A. Wedzicha & Alvar Agustí. (2017) Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Lung Disease 2017 Report. GOLD Executive Summary. American Journal of Respiratory and Critical Care Medicine 195:5, pages 557-582.
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Claus F. Vogelmeier, Gerard J. Criner, Fernando J. Martínez, Antonio Anzueto, Peter J. Barnes, Jean Bourbeau, Bartolome R. Celli, Rongchang Chen, Marc Decramer, Leonardo M. Fabbri, Peter Frith, David M.G. Halpin, M. Victorina López Varela, Masaharu Nishimura, Nicolás Roche, Roberto Rodríguez-Roisin, Don D. Sin, Dave Singh, Robert Stockley, Jørgen Vestbo, Jadwiga A. Wedzicha & Alvar Agustí. (2017) Informe 2017 de la Iniciativa Global para el Diagnóstico, Tratamiento y Prevención de la Enfermedad Pulmonar Obstructiva Crónica: Resumen Ejecutivo de GOLD. Archivos de Bronconeumología 53:3, pages 128-149.
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Claus F. Vogelmeier, Gerard J. Criner, Fernando J. Martinez, Antonio Anzueto, Peter J. Barnes, Jean Bourbeau, Bartolome R. Celli, Rongchang Chen, Marc Decramer, Leonardo M. Fabbri, Peter Frith, David M.G. Halpin, M. Victorina López Varela, Masaharu Nishimura, Nicolas Roche, Roberto Rodriguez-Roisin, Don D. Sin, Dave Singh, Robert Stockley, Jørgen Vestbo, Jadwiga A. Wedzicha & Alvar Agusti. (2017) Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Lung Disease 2017 Report: GOLD Executive Summary. Archivos de Bronconeumología (English Edition) 53:3, pages 128-149.
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Daniela Castiglia, Salvatore Battaglia, Alida Benfante, Claudio Sorino & Nicola Scichilone. (2016) Pharmacological Management of Elderly Patients with Asthma–Chronic Obstructive Pulmonary Disease Overlap Syndrome: Room for Speculation?. Drugs & Aging 33:6, pages 375-385.
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Siraj Ahmad, Farida Ahmad, Jameel Ahmad & Zuber Ahmad. (2022) Safety and Efficacy of Formoterol/Tiotropium Bromide and Formoterol/Glycopyrronium in Patients of Grade-2 COPD. SSRN Electronic Journal.
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