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Expert Review of Clinical Pharmacology Volume 4, 2011 - Issue 2
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Review

Regulation of appetite to treat obesity

Gilbert W Kim Department of Pharmacology and Experimental Therapeutics, Thomas Jefferson University, 132 S. 10th Street, 1170 Main, Philadelphia, PA 19107, USA; Department of Pharmacology and Experimental Therapeutics, Thomas Jefferson University, 132 S. 10th Street, 1170 Main, Philadelphia, PA 19107, USA
,
Jieru E Lin Department of Pharmacology and Experimental Therapeutics, Thomas Jefferson University, 132 S. 10th Street, 1170 Main, Philadelphia, PA 19107, USA; Department of Pharmacology and Experimental Therapeutics, Thomas Jefferson University, 132 S. 10th Street, 1170 Main, Philadelphia, PA 19107, USA
,
Michael A Valentino Department of Pharmacology and Experimental Therapeutics, Thomas Jefferson University, 132 S. 10th Street, 1170 Main, Philadelphia, PA 19107, USA; Department of Pharmacology and Experimental Therapeutics, Thomas Jefferson University, 132 S. 10th Street, 1170 Main, Philadelphia, PA 19107, USA
,
Francheska Colon-Gonzalez Department of Pharmacology and Experimental Therapeutics, Thomas Jefferson University, 132 S. 10th Street, 1170 Main, Philadelphia, PA 19107, USA; Department of Pharmacology and Experimental Therapeutics, Thomas Jefferson University, 132 S. 10th Street, 1170 Main, Philadelphia, PA 19107, USA
&
Scott A Waldman Department of Pharmacology and Experimental Therapeutics, Thomas Jefferson University, 132 S. 10th Street, 1170 Main, Philadelphia, PA 19107, USA;[email protected]
Pages 243-259 | Published online: 10 Jan 2014

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Amparo L. De la Fuente-Reynoso, Eliana Barrios De Tomasi & Jorge Juárez. (2022) Differential effects of citalopram on the intake of high fat or high carbohydrates diets in female and male rats. Nutritional Neuroscience 25:7, pages 1477-1487.
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Katelyn J. Carey & Wendy Vitek. (2020) Weight Cycling in Women: Adaptation or Risk?. Seminars in Reproductive Medicine 40:05/06, pages 277-282.
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Marina Rodriguez Sanchez, Yong Wang, Tiffany S. Cho, Wesley I. Schnapp, Matthew B. Schmit, Caohui Fang & Haijiang Cai. (2022) Dissecting a disynaptic central amygdala-parasubthalamic nucleus neural circuit that mediates cholecystokinin-induced eating suppression. Molecular Metabolism 58, pages 101443.
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Huiya Zhang & Shiyu Chen. (2022) Cyclic peptide drugs approved in the last two decades (2001–2021). RSC Chemical Biology 3:1, pages 18-31.
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Meetal Mehta, Nawfal W. Istfan & Caroline M. Apovian. (2021) Obesity: Overview of Weight Management. Endocrine Practice 27:6, pages 626-635.
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Li Wang, Chao-Chao Yu, Jia Li, Qing Tian & Yan-Jun Du. (2021) Mechanism of Action of Acupuncture in Obesity: A Perspective From the Hypothalamus. Frontiers in Endocrinology 12.
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Shiying Li, Yeram Kim, Jiande D. Z. Chen & Mohammad F. Madhoun. (2021) Intestinal Electrical Stimulation Alters Hypothalamic Expression of Oxytocin and Orexin and Ameliorates Diet-Induced Obesity in Rats. Obesity Surgery 31:4, pages 1664-1672.
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Laura E. Wild, Tanya L. Alderete, Noopur C. Naik, William B. Patterson, Paige K. Berger, Roshonda B. Jones, Jasmine F. Plows & Michael I. Goran. (2021) Specific amino acids but not total protein attenuate postpartum weight gain among Hispanic women from Southern California. Food Science & Nutrition 9:4, pages 1842-1850.
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Shiv Govind Rawat, Rajan Kumar Tiwari, Pratishtha Sonker, Rajendra Prakash Maurya, Naveen Kumar Vishvakarma & Ajay Kumar. 2021. Obesity and Cancer. Obesity and Cancer 209 233 .
Isabel Espinosa-Salinas, Rodrigo San-Cristobal, Gonzalo Colmenarejo, Viviana Loria-Kohen, Susana Molina, Guillermo Reglero, Ana Ramirez de Molina & J. Alfredo Martinez. (2020) Polymorphic Appetite Effects on Waist Circumference Depend on rs3749474 CLOCK Gene Variant. Nutrients 12:6, pages 1846.
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Azania T. Panicker, Priyanshi Desai, Sanika Karnik & Maushmi S. Kumar. 2020. Obesity and Diabetes. Obesity and Diabetes 921 934 .
Bethany A. Falls & Yan Zhang. (2018) Insights into the Allosteric Mechanism of Setmelanotide (RM-493) as a Potent and First-in-Class Melanocortin-4 Receptor (MC4R) Agonist To Treat Rare Genetic Disorders of Obesity through an in Silico Approach . ACS Chemical Neuroscience 10:3, pages 1055-1065.
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Yang Yu, Sung Jin Park & Michael J. Beyak. (2018) Inducible nitric oxide synthase‐derived nitric oxide reduces vagal satiety signalling in obese mice. The Journal of Physiology 597:6, pages 1487-1502.
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Elena Minakova, Jordan Lang, Jesus-Servando Medel-Matus, Georgianna G. Gould, Ashley Reynolds, Don Shin, Andrey Mazarati & Raman Sankar. (2019) Melanotan-II reverses autistic features in a maternal immune activation mouse model of autism. PLOS ONE 14:1, pages e0210389.
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Edward S. Bliss & Eliza Whiteside. (2018) The Gut-Brain Axis, the Human Gut Microbiota and Their Integration in the Development of Obesity. Frontiers in Physiology 9.
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Andrew J. Krentz & Gerardo Rodriguez-Araujo. (2017) Cardiovascular Outcome Trials of Diabetes and Obesity Drugs: Implications for Conditional Approval and Early Phase Clinical Development. Pharmaceutical Medicine 31:6, pages 399-421.
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Georgios ValsamakisPanagiota KonstantakouGeorge Mastorakos. (2017) New Targets for Drug Treatment of Obesity. Annual Review of Pharmacology and Toxicology 57:1, pages 585-605.
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A. J. Krentz, K. Fujioka & M. Hompesch. (2016) Evolution of pharmacological obesity treatments: focus on adverse side-effect profiles. Diabetes, Obesity and Metabolism 18:6, pages 558-570.
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Songbo Wang, Nana Xiang, Liusong Yang, Canjun Zhu, Xiaotong Zhu, Lina Wang, Ping Gao, Qianyun Xi, Yongliang Zhang, Gang Shu & Qingyan Jiang. (2016) Linoleic acid and stearic acid elicit opposite effects on AgRP expression and secretion via TLR4-dependent signaling pathways in immortalized hypothalamic N38 cells. Biochemical and Biophysical Research Communications 471:4, pages 566-571.
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Helena Buhmann, Carel W. le Roux & Marco Bueter. (2014) The gut–brain axis in obesity. Best Practice & Research Clinical Gastroenterology 28:4, pages 559-571.
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G. Valsamakis, K. Lois, S. Kumar & G. Mastorakos. (2014) New molecular targets in the pathophysiology of obesity and available treatment options under investigation. Clinical Obesity, pages n/a-n/a.
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Andrea Mastinu, Marilena Pira, Gérard Aimè Pinna, Carla Pisu, Maria Antonietta Casu, Roberta Reali, Stefania Marcello, Gabriele Murineddu & Paolo Lazzari. (2013) NESS06SM reduces body weight with an improved profile relative to SR141716A. Pharmacological Research 74, pages 94-108.
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Gilbert W. Kim, Jieru E. Lin & Scott A. Waldman. (2013) GUCY2C: at the intersection of obesity and cancer. Trends in Endocrinology & Metabolism 24:4, pages 165-173.
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Artur Bossowski, Barbara Czarnocka, Jerzy Harasymczuk, Anna Moniuszko, Krzysztof Bardadin, Anna Łyczkowska, Karolina Hanusek & Anna Bossowska. (2013) Identification of GPR39 Receptor and Ghrelin Receptor in Thyroid Tissues in Paediatric Patients with Immune and Non-Immune Thyroid Diseases. Hormone Research in Paediatrics 79:3, pages 130-136.
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Álvarez V. Verónica. (2012) Tratamiento farmacológico de la obesidad. Revista Médica Clínica Las Condes 23:2, pages 173-179.
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