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Expert Review of Clinical Pharmacology Volume 5, 2012 - Issue 3
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Review

Criteria for acetylcysteine treatment and clinical outcomes after paracetamol poisoning

W Stephen Waring Acute Medical Unit, York Hospital, Wigginton Road, York, YO31 8HE, UK. [email protected]
Pages 311-318 | Published online: 10 Jan 2014

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James W Dear & Daniel J Antoine. (2014) Stratification of paracetamol overdose patients using new toxicity biomarkers: current candidates and future challenges. Expert Review of Clinical Pharmacology 7:2, pages 181-189.
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Articles from other publishers (13)

Sonia Eligini, Benedetta Porro, Giancarlo Aldini, Susanna Colli & Cristina Banfi. (2022) N-Acetylcysteine Inhibits Platelet Function through the Regeneration of the Non-Oxidative Form of Albumin. Antioxidants 11:3, pages 445.
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Samuel James Offor, Cecilia Nwadiuto Amadi, Ifeyinwa Chijioke-Nwauche, Jose E. Manautou & Orish E. Orisakwe. (2022) Potential deleterious effects of paracetamol dose regime used in Nigeria versus that of the United States of America. Toxicology Reports 9, pages 1035-1044.
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Katy Saide, Victoria Sherwood & Grant N. Wheeler. (2019) Paracetamol-induced liver injury modelled in Xenopus laevis embryos. Toxicology Letters 302, pages 83-91.
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Gamal A. Salem, Ahmed Shaban, Hussain A. Diab, Wesam A. Elsaghayer, Manal D. Mjedib, Aomassad M. Hnesh & Ravi P. Sahu. (2018) Phoenix dactylifera protects against oxidative stress and hepatic injury induced by paracetamol intoxication in rats. Biomedicine & Pharmacotherapy 104, pages 366-374.
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A. D. Bastiaan Vliegenthart, Daniel J. Antoine & James W. Dear. (2015) Target biomarker profile for the clinical management of paracetamol overdose. British Journal of Clinical Pharmacology 80:3, pages 351-362.
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D. Nicholas Bateman. (2015) Changing the Management of Paracetamol Poisoning. Clinical Therapeutics 37:9, pages 2135-2141.
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Sean M. Frey, Timothy J. Wiegand, Jody L. Green, Kennon J. Heard, Diana G. Wilkins, Rachel M. Gorodetsky & Richard C. Dart. (2015) Confirming the Causative Role of Acetaminophen in Indeterminate Acute Liver Failure Using Acetaminophen-Cysteine Adducts. Journal of Medical Toxicology 11:2, pages 218-222.
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Kentaro Igami, Yosuke Shimojo, Hisatomi Ito, Toshitsugu Miyazaki & Yoshiki Kashiwada. (2015) Hepatoprotective effect of fermented ginseng and its major constituent compound K in a rat model of paracetamol (acetaminophen)-induced liver injury. Journal of Pharmacy and Pharmacology 67:4, pages 565-572.
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Manar Hamed Arafa, Dalia AbdElmoain Mohamed & Hebatallah Husseini Atteia. (2015) Ameliorative effect of N-acetyl cysteine on alpha-cypermethrin-induced pulmonary toxicity in male rats. Environmental Toxicology 30:1, pages 26-43.
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A. Karalija, L.N. Novikova, P.J. Kingham, M. Wiberg & L.N. Novikov. (2014) The effects of N-acetyl-cysteine and acetyl-l-carnitine on neural survival, neuroinflammation and regeneration following spinal cord injury. Neuroscience 269, pages 143-151.
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Gordon F. Rushworth & Ian L. Megson. (2014) Existing and potential therapeutic uses for N-acetylcysteine: The need for conversion to intracellular glutathione for antioxidant benefits. Pharmacology & Therapeutics 141:2, pages 150-159.
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G. Thompson, S. B. Fatima, N. Shah, G. Kitching & W. S. Waring. (2013) Impact of Amending the Acetylcysteine Marketing Authorisation on Treatment of Paracetamol Overdose. ISRN Toxicology 2013, pages 1-5.
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W. Stephen Waring. (2012) Novel acetylcysteine regimens for treatment of paracetamol overdose. Therapeutic Advances in Drug Safety 3:6, pages 305-315.
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