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Expert Review of Proteomics Volume 7, 2010 - Issue 1
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Review

Functional genomics and networks: new approaches in the extraction of complex gene modules

Pablo Minguez Department of Bioinformatics and Genomics, Centro de Investigación Príncipe Felipe (CIPF), Valencia, Spain and European Molecular Biology Laboratory, Meyerhofstrasse 1, 69117 Heidelberg, Germany
&
Joaquin Dopazo Department of Bioinformatics and Genomics, Centro de Investigación Príncipe Felipe (CIPF), Valencia, Spain and CIBER de Enfermedades Raras (CIBERER), Valencia, Spain and Functional Genomics Node, (INB) at CIPF, Valencia, Spain. [email protected]
Pages 55-63 | Published online: 09 Jan 2014

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ShaguftaH. Khan, Faizan Ahmad, Nihal Ahmad, DanielC. Flynn & Raj Kumar. (2011) Protein-Protein Interactions: Principles, Techniques, and their Potential Role in New Drug Development. Journal of Biomolecular Structure and Dynamics 28:6, pages 929-938.
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Weng Howe Chan, Mohd Saberi Mohamad, Safaai Deris, Nazar Zaki, Shahreen Kasim, Sigeru Omatu, Juan Manuel Corchado & Hany Al Ashwal. (2016) Identification of informative genes and pathways using an improved penalized support vector machine with a weighting scheme. Computers in Biology and Medicine 77, pages 102-115.
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S Mas, P Gassó, D Boloc, N Rodriguez, F Mármol, J Sánchez, M Bernardo & A Lafuente. (2015) Network analysis of gene expression in mice provides new evidence of involvement of the mTOR pathway in antipsychotic-induced extrapyramidal symptoms. The Pharmacogenomics Journal 16:3, pages 293-300.
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Sergi Mas, Patricia Gassó & Amelia Lafuente. (2015) Applicability of gene expression and systems biology to develop pharmacogenetic predictors; antipsychotic-induced extrapyramidal symptoms as an example. Pharmacogenomics 16:17, pages 1975-1988.
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S Mas, P Gassó, E Parellada, M Bernardo & A Lafuente. (2015) Network analysis of gene expression in peripheral blood identifies mTOR and NF-κB pathways involved in antipsychotic-induced extrapyramidal symptoms. The Pharmacogenomics Journal 15:5, pages 452-460.
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Lv Jin, Xiao-Yu Zuo, Wei-Yang Su, Xiao-Lei Zhao, Man-Qiong Yuan, Li-Zhen Han, Xiang Zhao, Ye-Da Chen & Shao-Qi Rao. (2014) Pathway-based Analysis Tools for Complex Diseases: A Review. Genomics, Proteomics & Bioinformatics 12:5, pages 210-220.
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María González‐del Pozo, Cristina Méndez‐Vidal, Javier Santoyo‐Lopez, Alicia Vela‐Boza, Nereida Bravo‐Gil, Antonio Rueda, Luz García‐Alonso, Carmen Vázquez‐Marouschek, Joaquín Dopazo, Salud Borrego & Guillermo Antiñolo. (2013) Deciphering intrafamilial phenotypic variability by exome sequencing in a Bardet–Biedl family. Molecular Genetics & Genomic Medicine 2:2, pages 124-133.
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Luz García-Alonso, Roberto Alonso, Enrique Vidal, Alicia Amadoz, Alejandro de María, Pablo Minguez, Ignacio Medina & Joaquín Dopazo. (2012) Discovering the hidden sub-network component in a ranked list of genes or proteins derived from genomic experiments. Nucleic Acids Research 40:20, pages e158-e158.
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Takeshi Nishiyama, Kunihiko Takahashi, Toshiro Tango, Dalila Pinto, Stephen W Scherer, Satoshi Takami & Hirohisa Kishino. (2011) A scan statistic to extract causal gene clusters from case-control genome-wide rare CNV data. BMC Bioinformatics 12:1.
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Gregor Warsow, Boris Greber, Steffi SI Falk, Clemens Harder, Marcin Siatkowski, Sandra Schordan, Anup Som, Nicole Endlich, Hans Schöler, Dirk Repsilber, Karlhans Endlich & Georg Fuellen. (2010) ExprEssence - Revealing the essence of differential experimental data in the context of an interaction/regulation net-work. BMC Systems Biology 4:1.
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