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Drug Profile

Microbiological profile of a new topical antibacterial: retapamulin ointment 1%

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Pages 269-279 | Published online: 10 Jan 2014

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Yunpeng Yi, Jiaming Zhang, Jiakun Zuo, Maolu Zhang, Shifa Yang, Zhongli Huang, Guiyu Li, Ruofeng Shang & Shuqian Lin. (2023) Novel pyridinium cationic pleuromutilin analogues overcoming bacterial multidrug resistance. European Journal of Medicinal Chemistry 251, pages 115269.
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Yunxing Fu, Chunqing Leng, Yuan Fan, Xia Ma, Xianghui Li, Xuefei Wang, Zhenghuan Guo, Xiujun Wang & Ruofeng Shang. (2021) In Vitro and In Vivo Activity of 14-O-[(4,6-Diamino-pyrimidine-2-yl) thioacetyl] Mutilin against Methicillin-Resistant Staphylococcus aureus. Molecules 26:11, pages 3277.
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Yun-Ge Li, Ju-Xian Wang, Guo-Ning Zhang, Mei Zhu, Xue-Fu You, Yu-Cheng Wang & Fan Zhang. (2020) Design, synthesis, and biological activity evaluation of a series of pleuromutilin derivatives with novel C14 side chains. Bioorganic & Medicinal Chemistry Letters 30:7, pages 126969.
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Yunxing Fu, Yu Liu, Yunpeng Yi, Jianping Liang, Qingfeng Wu & Ruofeng Shang. (2019) A Validated HPLC-MS/MS Assay for 14-O-[(4,6-Diaminopyrimidine-2-yl)thioacetyl] Mutilin in Biological Samples and Its Pharmacokinetic, Distribution and Excretion via Urine and Feces in Rats. Molecules 24:4, pages 790.
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Yunxing Fu, Lijun Ma, Yunpeng Yi, Yuan Fan, Jianping Liang & Ruofeng Shang. (2019) A new pleuromutilin candidate with potent antibacterial activity against Pasteurella multocida. Microbial Pathogenesis 127, pages 202-207.
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Ruofeng Shang, Yunpeng Yi, Chao Zhang, Yunxing Fu, Jianping Liang & Wanxia Pu. (2018) Antibacterial activity and pharmacokinetic profile of a promising antibacterial agent: 14- O -[(4-Amino-6-hydroxy-pyrimidine-2-yl)thioacetyl] mutilin. Pharmacological Research 129, pages 424-431.
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Woosung HongYil-Seob LeeChun-Wook ParkMoon-Soo YoonYoung Suck Ro. (2018) An Open Label, Multi-Center, Non-Interventional Post-Marketing Surveillance to Monitor the Safety and Efficacy of ALTARGO® (Retapamulin) Administered in Korean Patients According to the Prescribing Information. Annals of Dermatology 30:4, pages 441.
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Guirong Wang & Fengwu Zhao. (2017) Crystal structure of 5-hydroxy-4,6,9,10-tetramethyl-1-oxo-6-vinyldecahydro-3a,9-propanocyclopenta[8]annulen-8-yl 2-((2-methyl-1-(3-methylbenzamido)propan-2-yl)thio)acetate, C 34 H 49 NO 5 S . Zeitschrift für Kristallographie - New Crystal Structures 232:2, pages 173-176.
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Elena Galli, Iria Neri, Giampaolo Ricci, Ermanno Baldo, Maurizio Barone, Anna Belloni Fortina, Roberto Bernardini, Irene Berti, Carlo Caffarelli, Elisabetta Calamelli, Lucetta Capra, Rossella Carello, Francesca Cipriani, Pasquale Comberiati, Andrea Diociaiuti, Maya El Hachem, Elena Fontana, Michaela Gruber, Ellen Haddock, Nunzia Maiello, Paolo Meglio, Annalisa Patrizi, Diego Peroni, Dorella Scarponi, Ingrid Wielander & Lawrence F. Eichenfield. (2016) Consensus Conference on Clinical Management of pediatric Atopic Dermatitis. Italian Journal of Pediatrics 42:1.
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Tonny Tanus, Nicole E. Scangarella-Oman, Marybeth Dalessandro, Gang Li, John J. Breton & John F. Tomayko. (2014) A Randomized, Double-blind, Comparative Study to Assess the Safety and Efficacy of Topical Retapamulin Ointment 1% Versus Oral Linezolid in the Treatment of Secondarily Infected Traumatic Lesions and Impetigo Due to Methicillin-Resistant Staphylococcus aureus. Advances in Skin & Wound Care 27:12, pages 548-559.
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Ruofeng Shang, Xiuying Pu, Ximing Xu, Zhijun Xin, Chao Zhang, Wenzhu Guo, Yu Liu & Jianping Liang. (2014) Synthesis and Biological Activities of Novel Pleuromutilin Derivatives with a Substituted Thiadiazole Moiety as Potent Drug-Resistant Bacteria Inhibitors. Journal of Medicinal Chemistry 57:13, pages 5664-5678.
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