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Expert Review of Molecular Diagnostics Volume 10, 2010 - Issue 3
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Review

Engineered cystine-knot miniproteins for diagnostic applications

Harald Kolmar Clemens-Schöpf-Institut für Biochemie und Organische Chemie, Technische Universität Darmstadt, Petersenstraße 22, 64287 Darmstadt, Germany. [email protected]
Pages 361-368 | Published online: 09 Jan 2014

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Panchada Ch V Govindu, Athul Mohanan, Ashwini Dolle & Konkallu Hanumae Gowd. (2019) Conformations of cysteine disulfides of peptide toxins: Advantage of differentiating forward and reverse asymmetric disulfide conformers. Journal of Biomolecular Structure and Dynamics 37:8, pages 2017-2029.
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Shelley E Ackerman, Nicolas V Currier, Jamie M Bergen & Jennifer R Cochran. (2014) Cystine-knot peptides: emerging tools for cancer imaging and therapy. Expert Review of Proteomics 11:5, pages 561-572.
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Articles from other publishers (24)

Francis Alfred Attah, Bilqis Abiola Lawal, Abdulmalik Babatunde Yusuf, Oluwakorede Joshua Adedeji, Joy Temiloluwa Folahan, Kelvin Oluwafemi Akhigbe, Tithi Roy, Azeemat Adeola Lawal, Ngozi Blessing Ogah, Olufunke Esan Olorundare & Jean Christopher Chamcheu. (2022) Nutritional and Pharmaceutical Applications of Under-Explored Knottin Peptide-Rich Phytomedicines. Plants 11:23, pages 3271.
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Subhasis Mahari, Deepshikha Shahdeo, Ivneet Banga, Samraggi Choudhury & Sonu Gandhi. 2022. Peptide and Peptidomimetic Therapeutics. Peptide and Peptidomimetic Therapeutics 657 688 .
Nishant K. Mehta & Jennifer R. Cochran. 2017. Protein Therapeutics. Protein Therapeutics 161 188 .
Salvador Dueñas, Sergio A. Aguila & Genaro Pimienta. (2017) A workflow for in silico design of hIL-10 and ebvIL-10 inhibitors using well-known miniprotein scaffolds. Journal of Molecular Modeling 23:4.
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Ellen C. Gleeson, W. Roy Jackson & Andrea J. Robinson. (2016) Ring-closing metathesis in peptides. Tetrahedron Letters 57:39, pages 4325-4333.
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Miriam Góngora-Benítez, Judit Tulla-Puche & Fernando Albericio. (2013) Multifaceted Roles of Disulfide Bonds. Peptides as Therapeutics. Chemical Reviews 114:2, pages 901-926.
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Katalin E. Kövér & Gyula Batta. 2013. Amino Acids, Peptides and Proteins. Amino Acids, Peptides and Proteins 37 59 .
Frederic Zoller, Annette Markert, Philippe Barthe, Ulrike Hebling, Annette Altmann, Thomas Lindner, Walter Mier & Uwe Haberkorn. (2013) A Disulfide-Constrained Miniprotein with Striking Tumor-Binding Specificity Developed by Ribosome Display. Angewandte Chemie International Edition 52:45, pages 11760-11764.
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Frederic Zoller, Annette Markert, Philippe Barthe, Ulrike Hebling, Annette Altmann, Thomas Lindner, Walter Mier & Uwe Haberkorn. (2013) A Disulfide‐Constrained Miniprotein with Striking Tumor‐Binding Specificity Developed by Ribosome Display. Angewandte Chemie 125:45, pages 11976-11980.
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Sarah J. Moore, Cheuk Lun Leung, Heidi K. Norton & Jennifer R. Cochran. (2013) Engineering Agatoxin, a Cystine-Knot Peptide from Spider Venom, as a Molecular Probe for In Vivo Tumor Imaging. PLoS ONE 8:4, pages e60498.
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Ivan Coluzza, Peter D. J. van Oostrum, Barbara Capone, Erik Reimhult & Christoph Dellago. (2013) Sequence Controlled Self-Knotting Colloidal Patchy Polymers. Physical Review Letters 110:7.
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Han Jiang, Sarah J. Moore, Shuanglong Liu, Hongguang Liu, Zheng Miao, Frank V. Cochran, Yang Liu, Mei Tian, Jennifer R. Cochran, Hong Zhang & Zhen Cheng. (2012) A novel radiofluorinated agouti-related protein for tumor angiogenesis imaging. Amino Acids 44:2, pages 673-681.
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Bernhard Glotzbach, Stefan Schmelz, Michael Reinwarth, Andreas Christmann, Dirk W. Heinz & Harald Kolmar. (2012) Structural characterization of Spinacia oleracea trypsin inhibitor III (SOTI-III) . Acta Crystallographica Section D Biological Crystallography 69:1, pages 114-120.
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S Vink & PF Alewood. (2012) Targeting voltage-gated calcium channels: developments in peptide and small-molecule inhibitors for the treatment of neuropathic pain. British Journal of Pharmacology 167:5, pages 970-989.
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Frederic Zoller, Thimon Schwaebel, Annette Markert, Uwe Haberkorn & Walter Mier. (2012) Engineering and Functionalization of the Disulfide-Constrained Miniprotein Min-23 as a Scaffold for Diagnostic Application. ChemMedChem 7:2, pages 237-247.
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Sarah J. Moore, Cheuk Lun Leung & Jennifer R. Cochran. (2012) Knottins: disulfide-bonded therapeutic and diagnostic peptides. Drug Discovery Today: Technologies 9:1, pages e3-e11.
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Sarah J. Moore & Jennifer R. Cochran. 2012. Protein Engineering for Therapeutics, Part B. Protein Engineering for Therapeutics, Part B 223 251 .
Richard J. Clark & David J. Craik. 2012. Protein Engineering for Therapeutics, Part B. Protein Engineering for Therapeutics, Part B 57 74 .
A. Galat. (2011) Common structural traits for cystine knot domain of the TGFβ superfamily of proteins and three-fingered ectodomain of their cellular receptors. Cellular and Molecular Life Sciences 68:20, pages 3437-3451.
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Chang-Han Lee, Kyung-Jin Park, Sang Jick Kim, Ohsuk Kwon, Ki Jun Jeong, Ayeung Kim & Yong-Sung Kim. (2011) Generation of Bivalent and Bispecific Kringle Single Domains by Loop Grafting as Potent Agonists against Death Receptors 4 and 5. Journal of Molecular Biology 411:1, pages 201-219.
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Norelle L Daly & David J Craik. (2011) Bioactive cystine knot proteins. Current Opinion in Chemical Biology 15:3, pages 362-368.
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Lei Jiang, Zheng Miao, Richard H. Kimura, Hongguang Liu, Jennifer R. Cochran, Cathy S. Culter, Ande Bao, Peiyong Li & Zhen Cheng. (2010) Preliminary evaluation of 177Lu-labeled knottin peptides for integrin receptor-targeted radionuclide therapy. European Journal of Nuclear Medicine and Molecular Imaging 38:4, pages 613-622.
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Frederic Zoller, Uwe Haberkorn & Walter Mier. (2011) Miniproteins as Phage Display-Scaffolds for Clinical Applications. Molecules 16:3, pages 2467-2485.
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Richard H. Kimura, Douglas S. Jones, Lei Jiang, Zheng Miao, Zhen Cheng & Jennifer R. Cochran. (2011) Functional Mutation of Multiple Solvent-Exposed Loops in the Ecballium elaterium Trypsin Inhibitor-II Cystine Knot Miniprotein. PLoS ONE 6:2, pages e16112.
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