344
Views
20
CrossRef citations to date
0
Altmetric
Review

DNA methylation testing and marker validation using PCR: diagnostic applications

, , , &
Pages 75-92 | Published online: 09 Jan 2014

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (1)

Søren Kristiansen, Dorte Nielsen & György Sölétormos. (2014) Methylated DNA for monitoring tumor growth and regression: How do we get there?. Critical Reviews in Clinical Laboratory Sciences 51:3, pages 149-159.
Read now

Articles from other publishers (19)

Irina V. Botezatu, Valentina N. Kondratova, Anna M. Stroganova, Svetlana L. Dranko & Anatoly V. Lichtenstein. (2023) Aberrant methylation scanning by quantitative DNA melting analysis with hybridization probes as exemplified by liquid biopsy of SEPT9 and HIST1H4F in colorectal cancer. Clinica Chimica Acta 551, pages 117591.
Crossref
Butuo Li, Chao Jiang, Yiyue Xu, Xinyu Fan, Linlin Yang, Bing Zou, Bingjie Fan & Linlin Wang. (2022) Genome-wide DNA methylation signature predict clinical benefit of bevacizumab in non-small cell lung cancer. BMC Cancer 22:1.
Crossref
Gayatri R. Iyer, Prashant Utage, Radha Rama Devi, Kiran Kumar Vattam & Qurratulain Hasan. (2021) Expanding the clinico‐molecular spectrum of Angelman syndrome phenotype with the GABRG3 gene: Evidence from methylation and sequencing studies . Annals of Human Genetics 86:2, pages 71-79.
Crossref
Bing Li, Pei Hu, Lin-Bao Zhu, Ling-Ling You, Hui-Hua Cao, Jie Wang, Shang-Zhi Zhang, Ming-Hui Liu, Shahzad Toufeeq, Shou-Jun Huang & Jia-Ping Xu. (2020) DNA Methylation Is Correlated with Gene Expression during Diapause Termination of Early Embryonic Development in the Silkworm (Bombyx mori). International Journal of Molecular Sciences 21:2, pages 671.
Crossref
Hongding Zhang, Kun Zhang, Yuanyuan Yao, Yujie Liu, Ji Ji, Xuedong Huang, Jianwei Liu & Baohong Liu. (2019) Single-Molecule Fluorescence Imaging for Ultrasensitive DNA Methyltransferase Activity Measurement and Inhibitor Screening. Analytical Chemistry 91:15, pages 9500-9507.
Crossref
Gabriel Beikircher, Walter Pulverer, Manuela Hofner, Christa Noehammer & Andreas Weinhaeusel. 2018. DNA Methylation Protocols. DNA Methylation Protocols 407 424 .
Christina M. Burden & Jonathan E. Bobek. 2017. Handbook of Neurobehavioral Genetics and Phenotyping. Handbook of Neurobehavioral Genetics and Phenotyping 417 442 .
Marlene Remely, Heidrun Karlic, Irene Rebhan, Martina Greunz & Alexander G. Haslberger. 2017. Epigenetics and Gene Expression in Cancer, Inflammatory and Immune Diseases. Epigenetics and Gene Expression in Cancer, Inflammatory and Immune Diseases 115 134 .
Ram Vinay Pandey, Walter Pulverer, Rainer Kallmeyer, Gabriel Beikircher, Stephan Pabinger, Albert Kriegner & Andreas Weinhäusel. (2016) MSRE-HTPrimer: a high-throughput and genome-wide primer design pipeline optimized for epigenetic research. Clinical Epigenetics 8:1.
Crossref
Matthias Wielscher, Klemens Vierlinger, Ulrike Kegler, Rolf Ziesche, Andrea Gsur & Andreas Weinhäusel. (2015) Diagnostic Performance of Plasma DNA Methylation Profiles in Lung Cancer, Pulmonary Fibrosis and COPD. EBioMedicine 2:8, pages 929-936.
Crossref
Yunfei Ma, Honglian Zhang, Fangming Liu, Zhenhua Wu, Shaohua Lu, Qinghui Jin, Jianlong Zhao, Xinhua Zhong & Hongju Mao. (2015) Highly sensitive detection of DNA methylation levels by using a quantum dot-based FRET method. Nanoscale 7:41, pages 17547-17555.
Crossref
Daniel Burke, Shuang Fu, Michael Forbes-Smith, Somanath Bhat, Lina Partis, Thosaporn Coldham, Robert Frenkel & Kerry R Emslie. (2014) DNA methylation ratio variability may impede clinical application of cancer diagnostic markers. Analytical and Bioanalytical Chemistry 406:26, pages 6529-6537.
Crossref
George J. Besseris. (2014) A Fast-and-Robust Profiler for Improving Polymerase Chain Reaction Diagnostics. PLoS ONE 9:9, pages e108973.
Crossref
F. Zhang, Y.-C. Fan, N.-N Mu, J. Zhao, F.-K. Sun, Z.-H. Zhao, S. Gao & K. Wang. (2014) Exportin 4 gene expression and DNA promoter methylation status in chronic hepatitis B virus infection. Journal of Viral Hepatitis 21:4, pages 241-250.
Crossref
Ryan W Serra, Minggang Fang, Sung Mi Park, Lloyd Hutchinson & Michael R Green. (2014) A KRAS-directed transcriptional silencing pathway that mediates the CpG island methylator phenotype. eLife 3.
Crossref
Maria Chimonidou, Galatea Kallergi, Vassilis Georgoulias, Danny R. Welch & Evi S. Lianidou. (2013) Breast Cancer Metastasis Suppressor-1 Promoter Methylation in Primary Breast Tumors and Corresponding Circulating Tumor Cells. Molecular Cancer Research 11:10, pages 1248-1257.
Crossref
Johana A. Luna Coronell, Parvez Syed, Khulan Sergelen, István Gyurján & Andreas Weinhäusel. (2012) The current status of cancer biomarker research using tumour-associated antigens for minimal invasive and early cancer diagnostics. Journal of Proteomics 76, pages 102-115.
Crossref
Melanie R. Hassler & Gerda Egger. (2012) Epigenomics of cancer – emerging new concepts. Biochimie 94:11, pages 2219-2230.
Crossref
Lien Van De Voorde, Reinhart Speeckaert, Dirk Van Gestel, Marc Bracke, Wilfried De Neve, Joris Delanghe & Marijn Speeckaert. (2012) DNA methylation-based biomarkers in serum of patients with breast cancer. Mutation Research/Reviews in Mutation Research 751:2, pages 304-325.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.