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Review

Drug interactions involving the new second- and third-generation antiepileptic drugs

&
Pages 119-140 | Published online: 09 Jan 2014

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (27)

Gianluca D’Onofrio, Antonella Riva, Elisabetta Amadori, Simona Lattanzi, Klaus Rose, Alberto Verrotti & Pasquale Striano. (2022) Pharmacokinetic considerations surrounding the use of levetiracetam for seizure prophylaxis in neurocritical care – an overview. Expert Opinion on Drug Metabolism & Toxicology 18:9, pages 575-585.
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Rima Nabbout, N Chemaly, C Chiron & M. Kuchenbuch. (2021) Safety considerations selecting antiseizure medications for the treatment of individuals with Dravet syndrome. Expert Opinion on Drug Safety 20:5, pages 561-576.
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Diego Zapelini do Nascimento, Gabriela Moreno Marques & Fabiana Schuelter-Trevisol. (2021) Potential Psychotropic Drug Interactions among Drug-dependent People. Journal of Psychoactive Drugs 53:2, pages 168-176.
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Roberta Roberti, Caterina Palleria, Valentina Nesci, Martina Tallarico, Carlo Di Bonaventura, Emanuele Cerulli Irelli, Alessandra Morano, Giovambattista De Sarro, Emilio Russo & Rita Citraro. (2020) Pharmacokinetic considerations about antiseizure medications in the elderly. Expert Opinion on Drug Metabolism & Toxicology 16:10, pages 983-995.
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Cecilie Johannessen Landmark, Svein I. Johannessen & Philip N. Patsalos. (2020) Therapeutic drug monitoring of antiepileptic drugs: current status and future prospects. Expert Opinion on Drug Metabolism & Toxicology 16:3, pages 227-238.
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Alberto Verrotti, Renato Tambucci, Ludovica Di Francesco, Piero Pavone, Giulia Iapadre, Emma Altobelli, Sara Matricardi, Giovanni Farello & Vincenzo Belcastro. (2020) The role of polytherapy in the management of epilepsy: suggestions for rational antiepileptic drug selection. Expert Review of Neurotherapeutics 20:2, pages 167-173.
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Catherine Chiron. (2019) Stiripentol for the treatment of seizures associated with Dravet syndrome. Expert Review of Neurotherapeutics 19:4, pages 301-310.
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Alberto Verrotti, Giulia Iapadre, Giulia Di Donato, Ludovica Di Francesco, Luca Zagaroli, Sara Matricardi, Vincenzo Belcastro & Maria Laura Iezzi. (2019) Pharmacokinetic considerations for anti-epileptic drugs in children. Expert Opinion on Drug Metabolism & Toxicology 15:3, pages 199-211.
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Yvette Low, Sajita Setia & Graca Lima. (2018) Drug–drug interactions involving antidepressants: focus on desvenlafaxine. Neuropsychiatric Disease and Treatment 14, pages 567-580.
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Laurent M. Willems, Johann Philipp Zöllner, Esther Paule, Susanne Schubert-Bast, Felix Rosenow & Adam Strzelczyk. (2018) Eslicarbazepine acetate in epilepsies with focal and secondary generalised seizures: systematic review of current evidence. Expert Review of Clinical Pharmacology 11:3, pages 309-324.
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Srđan Stefanović, Slobodan M. Janković, Milan Novaković, Marko Milosavljević & Marko Folić. (2018) Pharmacodynamics and common drug-drug interactions of the third-generation antiepileptic drugs. Expert Opinion on Drug Metabolism & Toxicology 14:2, pages 153-159.
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Gabriel C Quintero. (2017) Review about gabapentin misuse, interactions, contraindications and side effects. Journal of Experimental Pharmacology 9, pages 13-21.
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Venkata Ramesh Yasam, Satya Lavanya Jakki, V. Senthil, M. Eswaramoorthy, S. Shanmuganathan, K. Arjunan & MJ Nanjan. (2016) A pharmacological overview of lamotrigine for the treatment of epilepsy. Expert Review of Clinical Pharmacology 9:12, pages 1533-1546.
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Krzysztof Łukawski, Paweł Gryta, Jarogniew Łuszczki & Stanisław J. Czuczwar. (2016) Exploring the latest avenues for antiepileptic drug discovery and development. Expert Opinion on Drug Discovery 11:4, pages 369-382.
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Claudiu T. Supuran. (2016) Drug interaction considerations in the therapeutic use of carbonic anhydrase inhibitors. Expert Opinion on Drug Metabolism & Toxicology 12:4, pages 423-431.
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Domenico Italiano, Edoardo Spina & Jose de Leon. (2014) Pharmacokinetic and pharmacodynamic interactions between antiepileptics and antidepressants. Expert Opinion on Drug Metabolism & Toxicology 10:11, pages 1457-1489.
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Luigi Grassi, Rosangela Caruso, Karen Hammelef, Maria Giulia Nanni & Michelle Riba. (2014) Efficacy and safety of pharmacotherapy in cancer-related psychiatric disorders across the trajectory of cancer care: A review. International Review of Psychiatry 26:1, pages 44-62.
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Petra Malátková & Vladimír Wsól. (2014) Carbonyl reduction pathways in drug metabolism. Drug Metabolism Reviews 46:1, pages 96-123.
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Sophia Yui Kau Fong, Yin Cheong Wong & Zhong Zuo. (2014) Alterations in the CNS effects of anti-epileptic drugs by Chinese herbal medicines. Expert Opinion on Drug Metabolism & Toxicology 10:2, pages 249-267.
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Cecilie Johannessen Landmark & Philip N Patsalos. (2012) Methodologies used to identify and characterize interactions among antiepileptic drugs. Expert Review of Clinical Pharmacology 5:3, pages 281-292.
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Philip N Patsalos & David J Berry. (2012) Pharmacotherapy of the third-generation AEDs: lacosamide, retigabine and eslicarbazepine acetate. Expert Opinion on Pharmacotherapy 13:5, pages 699-715.
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Jose de Leon, Vincenza Santoro, Concetta D'Arrigo & Edoardo Spina. (2012) Interactions between antiepileptics and second-generation antipsychotics. Expert Opinion on Drug Metabolism & Toxicology 8:3, pages 311-334.
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Ettore Beghi, Massimiliano Beghi & Cesare Maria Cornaggia. (2011) The use of recently approved antiepileptic drugs: use with caution, use in refractory patients or use as first-line indications?. Expert Review of Neurotherapeutics 11:12, pages 1759-1767.
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Markus Rauchenzauner & Gerhard Luef. (2011) Eslicarbazepine acetate for partial-onset seizures. Expert Review of Neurotherapeutics 11:12, pages 1673-1681.
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Markus Rauchenzauner & Gerhard Luef. (2010) Update on treatment of partial onset epilepsy: role of eslicarbazepine. Neuropsychiatric Disease and Treatment 6, pages 723-730.
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Christopher K. Finch, James Eason & Justin B. Usery. (2010) Gabapentin Withdrawal Syndrome in a Post–Liver Transplant Patient. Journal of Pain & Palliative Care Pharmacotherapy 24:3, pages 236-238.
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Charles J Vecht & Erik B Wilms. (2010) Seizures in low- and high-grade gliomas: current management and future outlook. Expert Review of Anticancer Therapy 10:5, pages 663-669.
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Philip N. PatsalosEdgar P. Spencer & Dave J. Berry. (2018) Therapeutic Drug Monitoring of Antiepileptic Drugs in Epilepsy: A 2018 Update. Therapeutic Drug Monitoring 40:5, pages 526-548.
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V. A. Karlov, P. N. Vlasov & I. A. Zhidkova. (2018) An open-label prospective clinical study of the efficacy and tolerability of brand-name and generic levetiracetam in the monotherapy of focal epilepsy in adults. Neurology, Neuropsychiatry, Psychosomatics 10:1S, pages 12-17.
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