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Review

IL-17 in human asthma

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Pages 173-186 | Published online: 09 Jan 2014

Keep up to date with the latest research on this topic with citation updates for this article.

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Ling Chen, Wanting Xu, Song Mao, Ruochen Zhu & Jianhua Zhang. (2022) Autoantibody of interleukin-17A induced by recombinant Mycobacterium smegmatis attenuates airway inflammation in mice with neutrophilic asthma. Journal of Asthma 59:10, pages 2117-2126.
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Marjorie M Walker, Nicholas Powell & Nicholas J Talley. (2014) Atopy and the gastrointestinal tract – a review of a common association in unexplained gastrointestinal disease. Expert Review of Gastroenterology & Hepatology 8:3, pages 289-299.
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Ji Young Kang, Sook Young Lee, Chin Kook Rhee, Seung Joon Kim, Soon Seog Kwon & Young Kyoon Kim. (2013) Effect of aging on airway remodeling and muscarinic receptors in a murine acute asthma model. Clinical Interventions in Aging 8, pages 1393-1403.
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Gaetano Caramori, Paolo Casolari & Ian Adcock. (2013) Role of Transcription Factors in the Pathogenesis of Asthma and COPD. Cell Communication & Adhesion 20:1-2, pages 21-40.
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Xiao-Lu Jie, Zi-Rui Luo, Jin Yu, Zhe-Ren Tong, Qiao-Qiao Li, Jia-Hui Wu, Yi Tao, Pei-Shi Feng, Ji-Ping Lan & Ping Wang. (2023) Pi-Pa-Run-Fei-Tang alleviates lung injury by modulating IL-6/JAK2/STAT3/IL-17 and PI3K/AKT/NF-κB signaling pathway and balancing Th17 and Treg in murine model of OVA-induced asthma. Journal of Ethnopharmacology 317, pages 116719.
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Deyang Sun, Xiaolu Cai, Fenglin Shen, Liming Fan, Huan Yang, Suqun Zheng, Linshui Zhou, Ke Chen & Zhen Wang. (2022) Transcriptome-Wide m6A Methylome and m6A-Modified Gene Analysis in Asthma. Frontiers in Cell and Developmental Biology 10.
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Tomasz Herjan, Jianxin XiaoMonika Dziendziel Kolanek. (2022) RNA-Binding Protein HuR Promotes Airway Inflammation in a House Dust Mite-Induced Allergic Asthma Model. Journal of Interferon & Cytokine Research 42:1, pages 29-38.
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A.K. Saikumar Jayalatha, L. Hesse, M.E. Ketelaar, G.H. Koppelman & M.C. Nawijn. (2021) The central role of IL-33/IL-1RL1 pathway in asthma: From pathogenesis to intervention. Pharmacology & Therapeutics 225, pages 107847.
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Yun Zhang, Xing Wang, He Zhang, Hongmei Tang, Hang Hu, Songping Wang, Vincent Kam Wai Wong, Yuying Li & Jun Deng. (2021) Autophagy Modulators From Chinese Herbal Medicines: Mechanisms and Therapeutic Potentials for Asthma. Frontiers in Pharmacology 12.
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Caihong Wang, Dan Wang, Huichao Zhao, Jing Wang, Nannan Liu, Hao Shi, Jiayu Tian, Xin Wang & Zhihong Zhang. (2021) Traffic-related PM2.5 and diverse constituents disturb the balance of Th17/Treg cells by STAT3/RORγt-STAT5/Foxp3 signaling pathway in a rat model of asthma. International Immunopharmacology 96, pages 107788.
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Hao Zhu, Yuhuan Shi, Shanshan Jiang, Xiuxiu Jiao, Hui Zhu, Rong Wang & Yongfang Yuan. (2021) Investigation of the Mechanisms of Chuankezhi Injection in the Treatment of Asthma Based on the Network Pharmacology Approach. Evidence-Based Complementary and Alternative Medicine 2021, pages 1-9.
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Rashmi Pandey, Ved Parkash, Surya Kant, AjayK Verma, SN Sankhwar, Avinash Agrawal, Devendra Parmar, Sheetal Verma & MdKaleem Ahmad. (2021) An update on the diagnostic biomarkers for asthma. Journal of Family Medicine and Primary Care 10:3, pages 1139.
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Jee Hye Wee, Woo Jin Bang, Min Woo Park, Soo-Hwan Byun & Hyo Geun Choi. (2021) Analysis of the relationship between asthma and benign prostatic hyperplasia. Medicine 100:11, pages e25214.
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Licheng Sun, Jinrong Fu, Sheng-Hao Lin, Jin-Lyu Sun, Li Xia, Ching-Hsiung Lin, Lijuan Liu, Caiyan Zhang, Lan Yang, Ping Xue, Xiang Wang, Saihua Huang, Xiao Han, Hua-Ling Chen, Ming-Shyan Huang, Xiaobo Zhang, Shau-Ku Huang & Yufeng Zhou. (2020) Particulate matter of 2.5 μm or less in diameter disturbs the balance of TH17/regulatory T cells by targeting glutamate oxaloacetate transaminase 1 and hypoxia-inducible factor 1α in an asthma model. Journal of Allergy and Clinical Immunology 145:1, pages 402-414.
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Arjun Mohan, Jon Grace, Anne Mainardi, Geoffrey Chupp & Njira Lugogo. 2020. Difficult To Treat Asthma. Difficult To Treat Asthma 123 153 .
Katarzyna Bulek, Xing Chen, Vandy Parron, Aparna Sundaram, Tomasz Herjan, Suidong Ouyang, Caini Liu, Alana Majors, Jarod Zepp, Ji Gao, Ashok Dongre, Malgorzata Bodaszewska-Lubas, Arnaud Echard, Mark Aronica, Julie Carman, Stavros Garantziotis, Dean Sheppard & Xiaoxia Li. (2019) IL-17A Recruits Rab35 to IL-17R to Mediate PKCα-Dependent Stress Fiber Formation and Airway Smooth Muscle Contractility. The Journal of Immunology 202:5, pages 1540-1548.
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Walker Julliard, John H. Fechner, Leah Owens, Chelsea A. O'Driscoll, Ling Zhou, Jeremy A. Sullivan, Lynn Frydrych, Amanda Mueller & Joshua D. Mezrich. (2017) Modeling the Effect of the Aryl Hydrocarbon Receptor on Transplant Immunity. Transplantation Direct 3:5, pages e157.
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Caini Liu, Liang Zhu, Koichi FukudaSuidong Ouyang, Xing Chen, Chenhui WangCun-jin ZhangBradley MartinChunfang GuLuke Qin, Suguna RachakondaMark AronicaJun QinXiaoxia Li. (2017) The flavonoid cyanidin blocks binding of the cytokine interleukin-17A to the IL-17RA subunit to alleviate inflammation in vivo. Science Signaling 10:467.
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Jian-Hui Chen, Ling Qin, Ying-Ying Shi, Jun-Tao Feng, Yu-Long Zheng, Yu-Feng Wan, Chuan-Qin Xu, Xiao-Mei Yang & Cheng-Ping Hu. (2016) IL-17 protein levels in both induced sputum and plasma are increased in stable but not acute asthma individuals with obesity. Respiratory Medicine 121, pages 48-58.
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Guiying Ruan, Baohong Tao, Dongguo Wang, Yong Li, Jingyi Wu & Genquan Yin. (2016) Chinese herbal medicine formula Gu-Ben-Fang-Xiao-Tang attenuates airway inflammation by modulating Th17/Treg balance in an ovalbumin-induced murine asthma model. Experimental and Therapeutic Medicine 12:3, pages 1428-1434.
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Ying Lei, Vamsi Boinapally, Anna Zoltowska, Mikael Adner, Lars Hellman & Gunnar Nilsson. (2015) Vaccination against IL-33 Inhibits Airway Hyperresponsiveness and Inflammation in a House Dust Mite Model of Asthma. PLOS ONE 10:7, pages e0133774.
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Emily P. Brigham, Meredith C. McCormack, Clifford M. Takemoto & Elizabeth C. Matsui. (2015) Iron Status is Associated with Asthma and Lung Function in US Women. PLOS ONE 10:2, pages e0117545.
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Rabih Halwani, Roua Al-Kufaidy, Alejandro Vazquez-Tello, Mary Angeline Pureza, Ahmed S. BaHammam, Hamdan Al-Jahdali, Sami A. Alnassar, Qutayba Hamid & Saleh Al-Muhsen. (2014) IL-17 Enhances Chemotaxis of Primary Human B Cells during Asthma. PLoS ONE 9:12, pages e114604.
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Agnes Hamzaoui, Anissa Berraïes, Besma Hamdi, Wajih Kaabachi, Jamel Ammar & Kamel Hamzaoui. (2014) Vitamin D reduces the differentiation and expansion of Th17 cells in young asthmatic children. Immunobiology 219:11, pages 873-879.
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J. L. Trevor & J. S. Deshane. (2014) Refractory asthma: mechanisms, targets, and therapy. Allergy 69:7, pages 817-827.
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Maximilian Schieck, Sven Michel, Kathrin Suttner, Thomas Illig, Sonja Zeilinger, Andre Franke, Christian Vogelberg, Andrea von Berg, Albrecht Bufe, Andrea Heinzmann, Otto Laub, Ernst Rietschel, Burkhard Simma, Thomas Frischer, Jon Genuneit, Sebastian Kerzel & Michael Kabesch. (2014) Genetic variation in TH17 pathway genes, childhood asthma, and total serum IgE levels. Journal of Allergy and Clinical Immunology 133:3, pages 888-891.
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Kian Fan Chung & Ian M. Adcock. (2013) How Variability in Clinical Phenotypes Should Guide Research into Disease Mechanisms in Asthma. Annals of the American Thoracic Society 10:Supplement, pages S109-S117.
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Yuuki Nagashio, Yumi Matsuura, Junki Miyamoto, Takashi Kometani, Takuya Suzuki & Soichi Tanabe. (2013) Hesperidin inhibits development of atopic dermatitis-like skin lesions in NC/Nga mice by suppressing Th17 activity. Journal of Functional Foods 5:4, pages 1633-1641.
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Maria Troitskaya, Anton Baysa, Jarle Vaage, Kristin Sand, Azzam Maghazachi & Guro Valen. (2012) Interleukin-17 (IL-17) Expression Is Reduced during Acute Myocardial Infarction: Role on Chemokine Receptor Expression in Monocytes and Their in Vitro Chemotaxis towards Chemokines. Toxins 4:12, pages 1427-1439.
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A. A. Maghazachi. (2012) Role of Natural Killer Cells in Multiple Sclerosis. ISRN Immunology 2012, pages 1-14.
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