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Perspective

The case for PfEMP1-based vaccines to protect pregnant women against Plasmodium falciparum malaria

Pages 1405-1414 | Published online: 09 Jan 2014

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Lars Hviid, Thomas Lavstsen & Anja TR Jensen. (2018) A vaccine targeted specifically to prevent cerebral malaria – is there hope?. Expert Review of Vaccines 17:7, pages 565-567.
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Nicaise Tuikue-Ndam & Phillipe Deloron. (2015) Developing vaccines to prevent malaria in pregnant women. Expert Opinion on Biological Therapy 15:8, pages 1173-1182.
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Articles from other publishers (26)

Lars Hviid, Mary Lopez-Perez, Mads Delbo Larsen & Gestur Vidarsson. (2022) No sweet deal: the antibody-mediated immune response to malaria. Trends in Parasitology 38:6, pages 428-434.
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Lars Hviid. (2020) Precipitated Malaria: It Never Rains but It Pours. Trends in Parasitology 36:9, pages 721-723.
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Anja Ramstedt Jensen, Yvonne Adams & Lars Hviid. (2019) Cerebral Plasmodium falciparum malaria: The role of PfEMP1 in its pathogenesis and immunity, and PfEMP1‐based vaccines to prevent it . Immunological Reviews 293:1, pages 230-252.
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Yvon Mbouamboua, Félix Koukouikila-Koussounda, Francine Ntoumi, Selorme Adukpo, Michael Kombo, Christevy Vouvoungui, Jacques van Helden & Simon Charles Kobawila. (2019) Sub-microscopic Plasmodium falciparum infections in matched peripheral, placental and umbilical cord blood samples from asymptomatic Congolese women at delivery. Acta Tropica 193, pages 142-147.
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Mary Lopez-Perez, Mads Delbo Larsen, Rafael Bayarri-Olmos, Paulina Ampomah, Liz Stevenson, Myriam Arévalo-Herrera, Sócrates Herrera & Lars Hviid. (2018) IgG Responses to the Plasmodium falciparum Antigen VAR2CSA in Colombia Are Restricted to Pregnancy and Are Not Induced by Exposure to Plasmodium vivax. Infection and Immunity 86:8.
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Sarah J. Pitt. 2017. Clinical Microbiology for Diagnostic Laboratory Scientists. Clinical Microbiology for Diagnostic Laboratory Scientists 149 192 .
Jaymin C. Patel, Nicholas J. Hathaway, Christian M. Parobek, Kyaw L. Thwai, Mwayiwawo Madanitsa, Carole Khairallah, Linda Kalilani-Phiri, Victor Mwapasa, Achille Massougbodji, Nadine Fievet, Jeffery A. Bailey, Feiko O. ter Kuile, Philippe Deloron, Stephanie M. Engel, Steve M. Taylor, Jonathan J. Juliano, Nicaise Tuikue Ndam & Steven R. Meshnick. (2017) Increased risk of low birth weight in women with placental malaria associated with P. falciparum VAR2CSA clade. Scientific Reports 7:1.
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Jan D. Warncke, Ioannis Vakonakis & Hans-Peter Beck. (2016) Plasmodium Helical Interspersed Subtelomeric (PHIST) Proteins, at the Center of Host Cell Remodeling. Microbiology and Molecular Biology Reviews 80:4, pages 905-927.
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Anine Jeppesen, Sisse Bolm Ditlev, Vladyslav Soroka, Liz Stevenson, Louise Turner, Ron Dzikowski, Lars Hviid & Lea Barfod. (2015) Multiple Plasmodium falciparum Erythrocyte Membrane Protein 1 Variants per Genome Can Bind IgM via Its Fc Fragment Fcμ. Infection and Immunity 83:10, pages 3972-3981.
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Justin Doritchamou, Audrey Sabbagh, Jakob S. Jespersen, Emmanuelle Renard, Ali Salanti, Morten A. Nielsen, Philippe Deloron & Nicaise Tuikue Ndam. (2015) Identification of a Major Dimorphic Region in the Functionally Critical N-Terminal ID1 Domain of VAR2CSA. PLOS ONE 10:9, pages e0137695.
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Lars Hviid, Lea Barfod & Freya J.I. Fowkes. (2015) Trying to remember: immunological B cell memory to malaria. Trends in Parasitology 31:3, pages 89-94.
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Lars Hviid & Anja T.R. Jensen. 2015. 51 84 .
Alfredo Mayor, Samad A. Ibitokou & Philippe Deloron. 2014. Encyclopedia of Malaria. Encyclopedia of Malaria 1 14 .
A. Teo, W. Hasang, L. M. Randall, G. Feng, L. Bell, H. Unger, C. Langer, J. G. Beeson, P. M. Siba, I. Mueller, M. E. Molyneux, G. V. Brown & S. J. Rogerson. (2014) Decreasing Malaria Prevalence and Its Potential Consequences for Immunity in Pregnant Women. Journal of Infectious Diseases 210:9, pages 1444-1455.
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Arnaud Chêne, Valérie Briand, Samad Ibitokou, Sébastien Dechavanne, Achille Massougbodji, Philippe Deloron, Adrian J. F. Luty, Benoît Gamain & Nadine Fievet. (2014) Placental Cytokine and Chemokine Profiles Reflect Pregnancy Outcomes in Women Exposed to Plasmodium falciparum Infection. Infection and Immunity 82:9, pages 3783-3789.
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Paulina Ampomah, Liz Stevenson, Michael F. Ofori, Lea Barfod & Lars Hviid. (2014) Kinetics of B Cell Responses to Plasmodium falciparum Erythrocyte Membrane Protein 1 in Ghanaian Women Naturally Exposed to Malaria Parasites . The Journal of Immunology 192:11, pages 5236-5244.
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Paulina Ampomah, Liz Stevenson, Michael F. Ofori, Lea Barfod & Lars Hviid. (2014) B-Cell Responses to Pregnancy-Restricted and -Unrestricted Plasmodium falciparum Erythrocyte Membrane Protein 1 Antigens in Ghanaian Women Naturally Exposed to Malaria Parasites. Infection and Immunity 82:5, pages 1860-1871.
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Ricardo Ataíde, Alfredo Mayor & Stephen J. Rogerson. (2014) Malaria, primigravidae, and antibodies: knowledge gained and future perspectives. Trends in Parasitology 30:2, pages 85-94.
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Sophie Borgella, Nadine Fievet, Bich-Tram Huynh, Samad Ibitokou, Gbetognon Hounguevou, Jacqueline Affedjou, Jean-Claude Sagbo, Parfait Houngbegnon, Blaise Guezo-Mévo, Achille Massougbodji, Adrian J. F. Luty, Michel Cot & Philippe Deloron. (2013) Impact of Pregnancy-Associated Malaria on Infant Malaria Infection in Southern Benin. PLoS ONE 8:11, pages e80624.
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Justin Doritchamou, Pascal Bigey, Morten Agertoug Nielsen, S?dami Gnidehou, Sem Ezinmegnon, Aurore Burgain, Achille Massougbodji, Philippe Deloron, Ali Salanti & Nicaise Tuikue Ndam. (2013) Differential adhesion-inhibitory patterns of antibodies raised against two major variants of the NTS-DBL2X region of VAR2CSA. Vaccine 31:41, pages 4516-4522.
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Sanne S. Berger, Louise Turner, Christian W. Wang, Jens E. V. Petersen, Maria Kraft, John P. A. Lusingu, Bruno Mmbando, Andrea M. Marquard, Dominique B. A. C. Bengtsson, Lars Hviid, Morten A. Nielsen, Thor G. Theander & Thomas Lavstsen. (2013) Plasmodium falciparum Expressing Domain Cassette 5 Type PfEMP1 (DC5-PfEMP1) Bind PECAM1. PLoS ONE 8:7, pages e69117.
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Justin Doritchamou, Gwladys Bertin, Azizath Moussiliou, Pascal Bigey, Firmine Viwami, Sem Ezinmegnon, Nadine Fievet, Achille Massougbodji, Philippe Deloron & Nicaise Tuikue Ndam. (2012) First-Trimester Plasmodium falciparum Infections Display a Typical ?Placental? Phenotype. The Journal of Infectious Diseases 206:12, pages 1911-1919.
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Freya JI. Fowkes, Rose McGready, Nadia J. Cross, Mirja Hommel, Julie A. Simpson, Salenna R. Elliott, Jack S. Richards, Kurt Lackovic, Jacher Viladpai-Nguen, David Narum, Takafumi Tsuboi, Robin F. Anders, Fran?ois Nosten & James G. Beeson. (2012) New Insights into Acquisition, Boosting, and Longevity of Immunity to Malaria in Pregnant Women. The Journal of Infectious Diseases 206:10, pages 1612-1621.
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Hermann AM Mucke. (2012) Patent Highlights. Pharmaceutical Patent Analyst 1:2, pages 137-143.
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Bita Bordbar, Nicaise Tuikue-Ndam, Pascal Bigey, Justin Doritchamou, Daniel Scherman & Philippe Deloron. (2012) Identification of Id1-DBL2X of VAR2CSA as a key domain inducing highly inhibitory and cross-reactive antibodies. Vaccine 30:7, pages 1343-1348.
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