732
Views
113
CrossRef citations to date
0
Altmetric
Review

MF59 adjuvant: the best insurance against influenza strain diversity

, , , &
Pages 447-462 | Published online: 09 Jan 2014

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (18)

Laura Sánchez-de Prada, Iván Sanz-Muñoz, Raúl Ortiz de Lejarazu, José María Eiros, Adolfo García-Sastre & Teresa Aydillo. (2022) Immunodominance hierarchy after seasonal influenza vaccination. Emerging Microbes & Infections 11:1, pages 2670-2679.
Read now
Ilaria Loperto, Andrea Simonetti, Antonio Nardone & Maria Triassi. (2019) Use of adjuvanted trivalent influenza vaccine in older-age adults: a systematic review of economic evidence. Human Vaccines & Immunotherapeutics 15:5, pages 1035-1047.
Read now
Eun-Ju Ko & Sang-Moo Kang. (2018) Immunology and efficacy of MF59-adjuvanted vaccines. Human Vaccines & Immunotherapeutics 14:12, pages 3041-3045.
Read now
Michael Bröker, Francesco Berti & Paolo Costantino. (2016) Factors contributing to the immunogenicity of meningococcal conjugate vaccines. Human Vaccines & Immunotherapeutics 12:7, pages 1808-1824.
Read now
Timo Vesikari, Aino Forstén, Ashwani Arora, Theodore Tsai & Ralf Clemens. (2015) Influenza vaccination in children primed with MF59®-adjuvanted or non-adjuvanted seasonal influenza vaccine. Human Vaccines & Immunotherapeutics 11:8, pages 2102-2112.
Read now
Paul Loubet, Solen Kerneis, Olivia Anselem, Vassilis Tsatsaris, Francois Goffinet & Odile Launay. (2014) Should expectant mothers be vaccinated against flu? A safety review. Expert Opinion on Drug Safety 13:12, pages 1709-1720.
Read now
Giovanni Della Cioppa, Uwe Nicolay, Kelly Lindert, Geert Leroux-Roels, Frédéric Clement, Flora Castellino, Cristina Galli, Nicola Groth, Yotam Levin & Giuseppe Del Giudice. (2014) A dose-ranging study in older adults to compare the safety and immunogenicity profiles of MF59®-adjuvanted and non-adjuvanted seasonal influenza vaccines following intradermal and intramuscular administration. Human Vaccines & Immunotherapeutics 10:6, pages 1701-1710.
Read now
Ethan C Settembre, Philip R Dormitzer & Rino Rappuoli. (2014) Bringing influenza vaccines into the 21st century. Human Vaccines & Immunotherapeutics 10:3, pages 600-604.
Read now
Orli Even-Or, Sarit Samira, Ronald Ellis, Eli Kedar & Yechezkel Barenholz. (2013) Adjuvanted influenza vaccines. Expert Review of Vaccines 12:9, pages 1095-1108.
Read now
Derek T O'Hagan, Tedodore F Tsai & Luis A Brito. (2013) Emulsion based vaccine adjuvants. Human Vaccines & Immunotherapeutics 9:8, pages 1698-1700.
Read now
Christopher B Fox & Jean Haensler. (2013) An update on safety and immunogenicity of vaccines containing emulsion-based adjuvants. Expert Review of Vaccines 12:7, pages 747-758.
Read now
Jessica C. Dong & Gary P. Kobinger. (2013) Hypothesis driven development of new adjuvants. Human Vaccines & Immunotherapeutics 9:4, pages 808-811.
Read now
Derek T O’Hagan, Gary S Ott, Gary Van Nest, Rino Rappuoli & Giuseppe Del Giudice. (2013) The history of MF59® adjuvant: a phoenix that arose from the ashes. Expert Review of Vaccines 12:1, pages 13-30.
Read now
Giovanni Della Cioppa, Uwe Nicolay, Kelly Lindert, Geert Leroux-Roels, Frederic Clement, Flora Castellino, Grazia Galli, Nicola Groth & Giuseppe Del Giudice. (2012) Superior immunogenicity of seasonal influenza vaccines containing full dose of MF59® adjuvant. Human Vaccines & Immunotherapeutics 8:2, pages 216-227.
Read now
Joseph U Igietseme, Francis O Eko & Carolyn M Black. (2011) Chlamydia vaccines: recent developments and the role of adjuvants in future formulations. Expert Review of Vaccines 10:11, pages 1585-1596.
Read now
Weiping Cao, Jin Hyang Kim, Tatiana Chirkova, Adrian J Reber, Renata Biber, David K Shay & Suryaprakash Sambhara. (2011) Improving immunogenicity and effectiveness of influenza vaccine in older adults. Expert Review of Vaccines 10:11, pages 1529-1537.
Read now
Zoltan Vajo. (2011) The seasonal influenza vaccine Agriflu®. Expert Review of Vaccines 10:11, pages 1513-1517.
Read now

Articles from other publishers (95)

Francesco Lapi, Alexander Domnich, Ettore Marconi, Alessandro Rossi, Ignazio Grattagliano & Claudio Cricelli. (2023) Examining the effectiveness and duration of adjuvanted vs . non‐adjuvanted influenza vaccines in protecting older adults against symptomatic SARS‐CoV‐2 infection . British Journal of Clinical Pharmacology.
Crossref
P. Sangeetha Vijayan, Joseph Xavier & Mohanan Parayanthala Valappil. (2023) A review of immune modulators and immunotherapy in infectious diseases. Molecular and Cellular Biochemistry.
Crossref
Aref SepasiMehri GhafourianMorteza TaghizadehMehdi Mahdavi. (2023) Formulation of Recombinant H1N1 Hemagglutinin in MF59 and Alum Adjuvants: A Comparison of the Vaccines Potency and Efficacy in BALB/C Mice. Viral Immunology 36:6, pages 401-408.
Crossref
Javier Castrodeza-Sanz, Iván Sanz-Muñoz & Jose M. Eiros. (2023) Adjuvants for COVID-19 Vaccines. Vaccines 11:5, pages 902.
Crossref
Irina V. Ustyugova, Svetlana Pougatcheva, Timothy Farrell, Tod Strugnell, Vardhini Ganesh, Konstantin B. Zeldovich, Sudha Chivukula, Ana P. Goncalvez & Mario Barro. (2023) AF03 adjuvant improves anti-hemagglutinin and anti-neuraminidase immune responses induced by licensed seasonal quadrivalent influenza vaccines in mice. Vaccine 41:12, pages 2022-2034.
Crossref
Donatella Panatto, Alexander Domnich, Maria Chironna, Daniela Loconsole, Christian Napoli, Alessandra Torsello, Ilaria Manini, Emanuele Montomoli, Elena Pariani, Silvana Castaldi, Andrea Orsi & Giancarlo Icardi. (2022) Surveillance of Severe Acute Respiratory Infection and Influenza Vaccine Effectiveness among Hospitalized Italian Adults, 2021/22 Season. Vaccines 11:1, pages 83.
Crossref
Cheng Chang, Nedzad Music, Michael Cheung, Evan Rossignol, Sukhmani Bedi, Harsh Patel, Mohammad Safari, Changkeun Lee, Gillis R. Otten, Ethan C. Settembre, Giuseppe Palladino & Yingxia Wen. (2022) Self-amplifying mRNA bicistronic influenza vaccines raise cross-reactive immune responses in mice and prevent infection in ferrets. Molecular Therapy - Methods & Clinical Development 27, pages 195-205.
Crossref
Zhengjun Chen, Xinyan Hao, Hairui Wang, Xiaofang Zhong, Xiaoyan Chen, Yuanhao Zhao, Yuandong Zhang, Guangsheng Du & Xun Sun. (2022) Smart combination of aluminum hydroxide and MF59 to induce strong cellular immune responses. Journal of Controlled Release 349, pages 699-711.
Crossref
Min Joo Choi, Jae-Won Yun, Joon Young Song, Karam Ko, Joaquin F. Mould & Hee Jin Cheong. (2022) A Comparative Analysis of Influenza-Associated Disease Burden with Different Influenza Vaccination Strategies for the Elderly Population in South Korea. Vaccines 10:9, pages 1387.
Crossref
Maochen Li, Han Wang, Lili Tian, Zehan Pang, Qingkun Yang, Tianqi Huang, Junfen Fan, Lihua Song, Yigang Tong & Huahao Fan. (2022) COVID-19 vaccine development: milestones, lessons and prospects. Signal Transduction and Targeted Therapy 7:1.
Crossref
B.C. Gärtner, T. Weinke, K. Wahle, A. Kwetkat, D. Beier, K.J. Schmidt & T.F. Schwarz. (2022) Importance and value of adjuvanted influenza vaccine in the care of older adults from a European perspective – A systematic review of recently published literature on real-world data. Vaccine 40:22, pages 2999-3008.
Crossref
Parismita Kalita & Timir Tripathi. (2022) Methodological advances in the design of peptide-based vaccines. Drug Discovery Today 27:5, pages 1367-1380.
Crossref
Zachary R. SiaXuedan HeAli ZhangJann C. AngShuai Shao, Amal SeffouhWei-Chiao HuangMichael R. D’AgostinoAmir Teimouri Dereshgi, Sambhara Suryaprakash, Joaquin OrtegaHanne Andersen, Matthew S. Miller, Bruce A. Davidson & Jonathan F. Lovell. (2021) A liposome-displayed hemagglutinin vaccine platform protects mice and ferrets from heterologous influenza virus challenge. Proceedings of the National Academy of Sciences 118:22.
Crossref
Maryam Behzadi, Bahareh Vakili, Alireza Ebrahiminezhad & Navid Nezafat. (2021) Iron nanoparticles as novel vaccine adjuvants. European Journal of Pharmaceutical Sciences 159, pages 105718.
Crossref
Kaito A. Nagashima & Jarrod J. Mousa. (2021) Next-Generation Influenza HA Immunogens and Adjuvants in Pursuit of a Broadly Protective Vaccine. Viruses 13:4, pages 546.
Crossref
Jeroen Pollet, Wen-Hsiang Chen & Ulrich Strych. (2021) Recombinant protein vaccines, a proven approach against coronavirus pandemics. Advanced Drug Delivery Reviews 170, pages 71-82.
Crossref
Jennifer Connors, Matthew R. Bell, Jennifer Marcy, Michele Kutzler & Elias K. Haddad. (2021) The impact of immuno-aging on SARS-CoV-2 vaccine development. GeroScience 43:1, pages 31-51.
Crossref
Daisuke Tokuhara & Norikatsu Hikita. (2021) Cord Blood-Based Approach to Assess Candidate Vaccine Adjuvants Designed for Neonates and Infants. Vaccines 9:2, pages 95.
Crossref
Sharon Vijayanand, Keegan Braz Gomes, Rikhav P. Gala, Mohammad N. Uddin & Martin J. D’Souza. (2020) Exploring the Potential of T-Cells for a Universal Influenza Vaccine. Vaccines 8:4, pages 598.
Crossref
Tania Gupta & Shishir K Gupta. (2020) Potential adjuvants for the development of a SARS-CoV-2 vaccine based on experimental results from similar coronaviruses. International Immunopharmacology 86, pages 106717.
Crossref
Yongjuan Zou, Nan Wu, Chunyu Miao, Hua Yue, Jie Wu & Guanghui Ma. (2020) A novel multiple emulsion enhanced immunity via its biomimetic delivery approach . Journal of Materials Chemistry B 8:33, pages 7365-7374.
Crossref
Donatella Panatto, Mendel Haag, Piero Luigi Lai, Sylvie Tomczyk, Daniela Amicizia & Maria Maddalena Lino. (2019) Enhanced Passive Safety Surveillance (EPSS) confirms an optimal safety profile of the use of MF59 ® ‐adjuvanted influenza vaccine in older adults: Results from three consecutive seasons . Influenza and Other Respiratory Viruses 14:1, pages 61-66.
Crossref
Manish M. Patel, William Davis, Lauren Beacham, Sarah Spencer, Angela P. Campbell, Kathryn Lafond, Melissa Rolfes, Min Z. Levine, Eduardo Azziz-Baumgartner, Mark G. Thompson & Alicia M. Fry. (2020) Priming with MF59 adjuvanted versus nonadjuvanted seasonal influenza vaccines in children – A systematic review and a meta-analysis. Vaccine 38:3, pages 608-619.
Crossref
Carolyn M. Boudreau, Wen-Han Yu, Todd J. Suscovich, H. Keipp Talbot, Kathryn M. Edwards & Galit Alter. (2019) Selective induction of antibody effector functional responses using MF59-adjuvanted vaccination. Journal of Clinical Investigation 130:2, pages 662-672.
Crossref
Million A. Tegenge, Linda S. Von Tungeln, Steven A. Anderson, Robert J. Mitkus, Michelle M. Vanlandingham, Richard A. Forshee & Frederick A. Beland. (2019) Comparative pharmacokinetic and biodistribution study of two distinct squalene-containing oil-in-water emulsion adjuvants in H5N1 influenza vaccines. Regulatory Toxicology and Pharmacology 108, pages 104436.
Crossref
Bin Zhao, Jun Lian, Danyang Wang, Quanxiao Li, Shuangshuang Feng, Jinyao Li & Ailian Zhang. (2019) Evaluation of aqueous extracts of Cistanche deserticola as a polysaccharide adjuvant for seasonal influenza vaccine in young adult mice. Immunology Letters 213, pages 1-8.
Crossref
Thomas Trimaille, Céline Lacroix & Bernard Verrier. (2019) Self-assembled amphiphilic copolymers as dual delivery system for immunotherapy. European Journal of Pharmaceutics and Biopharmaceutics 142, pages 232-239.
Crossref
Zhijun Liu, Jiaxi Ru, Shiqi Sun, Zhidong Teng, Hu Dong, Pin Song, Yunshang Yang & Huichen Guo. (2019) Uniform dendrimer-like mesoporous silica nanoparticles as a nano-adjuvant for foot-and-mouth disease virus-like particle vaccine. Journal of Materials Chemistry B 7:21, pages 3446-3454.
Crossref
Carolyn M. Boudreau & Galit Alter. (2019) Extra-Neutralizing FcR-Mediated Antibody Functions for a Universal Influenza Vaccine. Frontiers in Immunology 10.
Crossref
R. Hoare, S.-J. Jung, T.P.H. Ngo, K. Bartie, J. Bailey, K.D. Thompson & A. Adams. (2019) Efficacy and safety of a non-mineral oil adjuvanted injectable vaccine for the protection of Atlantic salmon (Salmo salar L.) against Flavobacterium psychrophilum. Fish & Shellfish Immunology 85, pages 44-51.
Crossref
Fiona Ecarnot, Stefania Maggi & Jean-Pierre Michel. 2019. Reference Module in Biomedical Sciences. Reference Module in Biomedical Sciences.
Jaspreet Singh Kochhar, Justin J. Y. Tan, Yee Chin Kwang & Lifeng KangJaspreet Singh Kochhar, Justin J. Y. Tan, Yee Chin Kwang & Lifeng Kang. 2019. Microneedles for Transdermal Drug Delivery. Microneedles for Transdermal Drug Delivery 95 144 .
Shaohui Song, Ze Liu, Jian Zhou, Wei Cai, Huijuan Yang, Lei Ma, Jingxia Gao, Weidong Li & Guoyang Liao. (2018) An adjuvant compound that enhances immunogenicity at fractional doses of the Sabin‐inactivated poliovirus vaccine (sIPV) with a long duration of protection in a rat model. Journal of Medical Virology 91:1, pages 14-21.
Crossref
Nikunj M. Shukla, Kei-Ichiro Arimoto, Shiyin Yao, Jun-Bao Fan, Yue Zhang, Fumi Sato-Kaneko, Fitzgerald S. Lao, Tadashi Hosoya, Karen Messer, Minya Pu, Howard B. Cottam, Dennis A. Carson, Tomoko Hayashi, Dong-Er Zhang & Maripat Corr. (2018) Identification of Compounds That Prolong Type I Interferon Signaling as Potential Vaccine Adjuvants. SLAS Discovery 23:9, pages 960-973.
Crossref
William Schaffner, Paul van Buynder, Shelly McNeil & Albert D. M. E. Osterhaus. (2018) Seasonal influenza immunisation: Strategies for older adults. International Journal of Clinical Practice 72:10, pages e13249.
Crossref
William Schaffner, Wilbur H. Chen, Robert H. Hopkins & Kathleen Neuzil. (2018) Effective Immunization of Older Adults Against Seasonal Influenza. The American Journal of Medicine 131:8, pages 865-873.
Crossref
Jiong Wang, Shannon P. Hilchey, Marta DeDiego, Sheldon Perry, Ollivier Hyrien, Aitor Nogales, Jessica Garigen, Fatima Amanat, Nelson Huertas, Florian Krammer, Luis Martinez-Sobrido, David J. Topham, John J. Treanor, Mark Y. Sangster & Martin S. Zand. (2018) Broad cross-reactive IgG responses elicited by adjuvanted vaccination with recombinant influenza hemagglutinin (rHA) in ferrets and mice. PLOS ONE 13:4, pages e0193680.
Crossref
Alfred Harding & Nicholas Heaton. (2018) Efforts to Improve the Seasonal Influenza Vaccine. Vaccines 6:2, pages 19.
Crossref
E. Clemens, Carolien van de Sandt, Sook Wong, Linda Wakim & Sophie Valkenburg. (2018) Harnessing the Power of T Cells: The Promising Hope for a Universal Influenza Vaccine. Vaccines 6:2, pages 18.
Crossref
Cheng Zhao, YongKyoung Kim, Yining Zeng, Man Li, Xin Wang, Cheng Hu, Connor Gorman, Susie Y. Dai, Shi-You Ding & Joshua S. Yuan. (2018) Co-Compartmentation of Terpene Biosynthesis and Storage via Synthetic Droplet . ACS Synthetic Biology 7:3, pages 774-781.
Crossref
Liu-yang Yang, Heng Zhou, Yun Yang, Ya-nan Tong, Liu-sheng Peng, Bao-hang Zhu, Wei-bo Diao, Hao Zeng, Hong-wu Sun & Quan-ming Zou. (2018) Protective effects of a nanoemulsion adjuvant vaccine (2C-Staph/NE) administered intranasally against invasive Staphylococcus aureus pneumonia . RSC Advances 8:18, pages 9996-10008.
Crossref
Peter H. Goff, Tomoko Hayashi, Wenqian He, Shiyin Yao, Howard B. Cottam, Gene S. Tan, Brian Crain, Florian Krammer, Karen Messer, Minya Pu, Dennis A. Carson, Peter Palese & Maripat Corr. (2017) Synthetic Toll-Like Receptor 4 (TLR4) and TLR7 Ligands Work Additively via MyD88 To Induce Protective Antiviral Immunity in Mice. Journal of Virology 91:19.
Crossref
Michael Chan, Alast Ahmadi, Shiyin Yao, Fumi Sato-Kaneko, Karen Messer, Minya Pu, Brandon Nguyen, Tomoko Hayashi, Maripat Corr, Dennis A. Carson, Howard B. Cottam & Nikunj M. Shukla. (2017) Identification of Biologically Active Pyrimido[5,4- b ]indoles That Prolong NF-κB Activation without Intrinsic Activity . ACS Combinatorial Science 19:8, pages 533-543.
Crossref
Y Natori, A Humar, J Lipton, D D Kim, P Ashton, K Hoschler & D Kumar. (2017) A pilot randomized trial of adjuvanted influenza vaccine in adult allogeneic hematopoietic stem cell transplant recipients. Bone Marrow Transplantation 52:7, pages 1016-1021.
Crossref
Sang-Mu Shim, Eun-Jung Song, Daesub Song, Tae-Young Lee, Doo-Jin Kim, Jeong-Hyun Nam, Dae Gwin Jeong, Chong-Kil Lee, Sang-Hyun Kim & Jeong-Ki Kim. (2017) Nontoxic outer membrane vesicles efficiently increase the efficacy of an influenza vaccine in mice and ferrets. Vaccine 35:30, pages 3741-3748.
Crossref
Michael Schotsaert & Adolfo García-Sastre. (2017) Inactivated influenza virus vaccines: the future of TIV and QIV. Current Opinion in Virology 23, pages 102-106.
Crossref
Tae-Young Lee, Chang-Ung Kim, Eun-Hye Bae, Sang-Hwan Seo, Dae Gwin Jeong, Sun-Woo Yoon, Kyu-Tae Chang, Young Sang Kim, Sang-Hyun Kim & Doo-Jin Kim. (2017) Outer membrane vesicles harboring modified lipid A moiety augment the efficacy of an influenza vaccine exhibiting reduced endotoxicity in a mouse model. Vaccine 35:4, pages 586-595.
Crossref
T. Barclay & N. Petrovsky. 2017. Micro and Nanotechnology in Vaccine Development. Micro and Nanotechnology in Vaccine Development 127 147 .
K.L. Wilson, S.D. Xiang & M. Plebanski. 2017. Micro and Nanotechnology in Vaccine Development. Micro and Nanotechnology in Vaccine Development 99 125 .
Birgit Weinberger. 2017. The Ageing Immune System and Health. The Ageing Immune System and Health 69 86 .
Ruchi R. Shah, Kimberly J. Hassett & Luis A. Brito. 2017. Vaccine Adjuvants. Vaccine Adjuvants 1 13 .
Yotam Levin, Efrat Kochba, Georgi Shukarev, Sarah Rusch, Guillermo Herrera-Taracena & Pierre van Damme. (2016) A phase 1, open-label, randomized study to compare the immunogenicity and safety of different administration routes and doses of virosomal influenza vaccine in elderly. Vaccine 34:44, pages 5262-5272.
Crossref
Elise K. Pasoreck, Jin Su, Ian M. Silverman, Sager J. Gosai, Brian D. Gregory, Joshua S. Yuan & Henry Daniell. (2016) Terpene metabolic engineering via nuclear or chloroplast genomes profoundly and globally impacts off‐target pathways through metabolite signalling . Plant Biotechnology Journal 14:9, pages 1862-1875.
Crossref
Niels Peter H. Knudsen, Anja Olsen, Cecilia Buonsanti, Frank Follmann, Yuan Zhang, Rhea N. Coler, Christopher B. Fox, Andreas Meinke, Ugo D´Oro, Daniele Casini, Alessandra Bonci, Rolf Billeskov, Ennio De Gregorio, Rino Rappuoli, Ali M. Harandi, Peter Andersen & Else Marie Agger. (2016) Different human vaccine adjuvants promote distinct antigen-independent immunological signatures tailored to different pathogens. Scientific Reports 6:1.
Crossref
Derek T O'Hagan. 2005. Encyclopedia of Life Sciences. Encyclopedia of Life Sciences 1 7 .
Derek T. O’Hagan & Christopher B. Fox. (2015) New generation adjuvants – From empiricism to rational design. Vaccine 33, pages B14-B20.
Crossref
Steven Black. (2015) Safety and effectiveness of MF-59 adjuvanted influenza vaccines in children and adults. Vaccine 33, pages B3-B5.
Crossref
Million A. Tegenge & Robert J. Mitkus. (2015) A first-generation physiologically based pharmacokinetic (PBPK) model of alpha-tocopherol in human influenza vaccine adjuvant. Regulatory Toxicology and Pharmacology 71:3, pages 353-364.
Crossref
Byeong-Jae Lee, Hyeok-il Kwon, Eun-Ha Kim, Su-Jin Park, Sang-Ho Lee, Young Ki Choi & Sang-Hyun Kim. (2014) Assessment of mOMV adjuvant efficacy in the pathogenic H1N1 influenza virus vaccine. Clinical and Experimental Vaccine Research 3:2, pages 194.
Crossref
Roberto Adamo, Qi-Ying Hu, Antonella Torosantucci, Stefano Crotti, Giulia Brogioni, Martin Allan, Paola Chiani, Carla Bromuro, Douglas Quinn, Marta Tontini & Francesco Berti. (2014) Deciphering the structure–immunogenicity relationship of anti- Candida glycoconjugate vaccines . Chem. Sci. 5:11, pages 4302-4311.
Crossref
Rajesh K. Gupta. 2010. Pharmaceutical Sciences Encyclopedia. Pharmaceutical Sciences Encyclopedia 1 32 .
. (2013) Statement on Seasonal Influenza Vaccine for 2013–2014. Canada Communicable Disease Report 39:ACS-4, pages 1-37.
Crossref
Byeong-Jae Lee, Sang-Ho Lee, Min-Suk Song, Philippe Noriel Q. Pascua, Hyeok-il Kwon, Su-Jin Park, Eun-Ha Kim, Arun Decano, Se Mi Kim, Gyo Jin Lim, Doo-Jin Kim, Kyu-Tae Chang, Sang-Hyun Kim & Young Ki Choi. (2013) Adjuvant efficacy of mOMV against avian influenza virus infection in mice. Journal of Microbiology 51:5, pages 682-688.
Crossref
Million A. Tegenge & Robert J. Mitkus. (2013) A physiologically-based pharmacokinetic (PBPK) model of squalene-containing adjuvant in human vaccines. Journal of Pharmacokinetics and Pharmacodynamics 40:5, pages 545-556.
Crossref
Rosanna Leuzzi, Janice Spencer, Anthony Buckley, Cecilia Brettoni, Manuele Martinelli, Lorenza Tulli, Sara Marchi, Enrico Luzzi, June Irvine, Denise Candlish, Daniele Veggi, Werner Pansegrau, Luigi Fiaschi, Silvana Savino, Erwin Swennen, Osman Cakici, Ernesto Oviedo-Orta, Monica Giraldi, Barbara Baudner, Nunzia D'Urzo, Domenico Maione, Marco Soriani, Rino Rappuoli, Mariagrazia Pizza, Gillian R. Douce & Maria Scarselli. (2013) Protective Efficacy Induced by Recombinant Clostridium difficile Toxin Fragments. Infection and Immunity 81:8, pages 2851-2860.
Crossref
C. Colonna, R. Dorati, B. Conti, P. Caliceti & I. Genta. (2013) Sub-unit vaccine against S. aureus-mediated infections: Set-up of nano-sized polymeric adjuvant. International Journal of Pharmaceutics 452:1-2, pages 390-401.
Crossref
S. Kommareddy, B.C. Baudner, A. Bonificio, S. Gallorini, G. Palladino, A.S. Determan, D.M. Dohmeier, K.D. Kroells, J.R. Sternjohn, M. Singh, P.R. Dormitzer, K.J. Hansen & D.T. O’Hagan. (2013) Influenza subunit vaccine coated microneedle patches elicit comparable immune responses to intramuscular injection in guinea pigs. Vaccine 31:34, pages 3435-3441.
Crossref
Diana BoraschiM. Teresa AguadoCatherine DutelJörg GoronzyJacques LouisBeatrix Grubeck-LoebensteinRino RappuoliGiuseppe Del Giudice. (2013) The Gracefully Aging Immune System. Science Translational Medicine 5:185.
Crossref
Anne Louise Bischoff, Nilofar Vahman Følsgaard, Charlotte Giwercman Carson, Jakob Stokholm, Louise Pedersen, Maria Holmberg, Amalie Bisgaard, Sune Birch, Theodore F. Tsai & Hans Bisgaard. (2013) Altered Response to A(H1N1)pnd09 Vaccination in Pregnant Women: A Single Blinded Randomized Controlled Trial. PLoS ONE 8:4, pages e56700.
Crossref
Béatris Mastelic, David J.M. Lewis, Hana Golding, Ian Gust, Rebecca Sheets & Paul-Henri Lambert. (2013) Potential use of inflammation and early immunological event biomarkers in assessing vaccine safety. Biologicals 41:2, pages 115-124.
Crossref
Martina Prelog. (2013) Differential Approaches for Vaccination from Childhood to Old Age. Gerontology 59:3, pages 230-239.
Crossref
Qi-Ying Hu, Martin Allan, Roberto Adamo, Doug Quinn, Huili Zhai, Guangxiang Wu, Kirk Clark, Jing Zhou, Sonia Ortiz, Bing Wang, Elisa Danieli, Stefano Crotti, Marta Tontini, Giulia Brogioni & Francesco Berti. (2013) Synthesis of a well-defined glycoconjugate vaccine by a tyrosine-selective conjugation strategy. Chemical Science 4:10, pages 3827.
Crossref
Kimberly J. Hassett, Pradyot Nandi & Theodore W. Randolph. 2013. Sterile Product Development. Sterile Product Development 145 164 .
Iván Bihari, Gyula Pánczél, Jozsef Kovacs, Jenny Beygo & Elena Fragapane. (2012) Assessment of Antigen-Specific and Cross-Reactive Antibody Responses to an MF59-Adjuvanted A/H5N1 Prepandemic Influenza Vaccine in Adult and Elderly Subjects. Clinical and Vaccine Immunology 19:12, pages 1943-1948.
Crossref
Christopher H. CleggRichard RoqueNeal Van HoevenLucy PerroneSusan L. BaldwinJoseph A. RiningerRichard A. Bowen & Steven G. Reed. (2012) Adjuvant solution for pandemic influenza vaccine production. Proceedings of the National Academy of Sciences 109:43, pages 17585-17590.
Crossref
Humberto Reynales, Pedro Astudillo, Serge de Vallière, Christoph Hatz, Patricia Schlagenhauf, Barbara Rath, Priscilla Velentgas, Ariel Fariña, Victor Sales-Carmona & Nicola Groth. (2012) A prospective observational safety study on MF59® adjuvanted cell culture-derived vaccine, Celtura® during the A/H1N1 (2009) influenza pandemic. Vaccine 30:45, pages 6436-6443.
Crossref
Roberto Adamo, Maria R. Romano, Francesco Berti, Rosanna Leuzzi, Marta Tontini, Elisa Danieli, Emilia Cappelletti, Osman S. Cakici, Erwin Swennen, Vittoria Pinto, Barbara Brogioni, Daniela Proietti, Cesira L. Galeotti, Luigi Lay, Mario A. Monteiro, Maria Scarselli & Paolo Costantino. (2012) Phosphorylation of the Synthetic Hexasaccharide Repeating Unit Is Essential for the Induction of Antibodies to Clostridium difficile PSII Cell Wall Polysaccharide . ACS Chemical Biology 7:8, pages 1420-1428.
Crossref
. (2012) STATEMENT ON SEASONAL INFLUENZA VACCINE FOR 2012-2013. Canada Communicable Disease Report 38:ACS-2, pages 1-36.
Crossref
Adriana Baz Morelli, Dorit Becher, Sandra Koernig, Anabel Silva, Debbie Drane & Eugene Maraskovsky. (2012) ISCOMATRIX: a novel adjuvant for use in prophylactic and therapeutic vaccines against infectious diseases. Journal of Medical Microbiology 61:7, pages 935-943.
Crossref
Wolfgang W Leitner. (2012) Vaccine adjuvants: is the pipeline clogged?. Immunotherapy 4:6, pages 565-567.
Crossref
D.T. O’Hagan, G.S. Ott, E. De Gregorio & A. Seubert. (2012) The mechanism of action of MF59 – An innately attractive adjuvant formulation. Vaccine 30:29, pages 4341-4348.
Crossref
Carl R Alving, Kristina K Peachman, Mangala Rao & Steven G Reed. (2012) Adjuvants for human vaccines. Current Opinion in Immunology 24:3, pages 310-315.
Crossref
Erin M. Fisher & Jiu Jiang. (2012) Adjuvanted vaccines against influenza in the elderly. Frontiers in Biology 7:3, pages 221-226.
Crossref
Joon Young Song, Hee Jin Cheong, Yu Bin Seo, In Seon Kim, Ji Yun Noh, Jung Yeon Heo, Won Suk Choi, Jacob Lee & Woo Joo Kim. (2012) Comparison of the Long-Term Immunogenicity of Two Pandemic Influenza A/H1N1 2009 Vaccines, the MF59-Adjuvanted and Unadjuvanted Vaccines, in Adults. Clinical and Vaccine Immunology 19:5, pages 638-641.
Crossref
Mariarosaria Marinaro, Giovanni Rezza, Giuseppe Del Giudice, Valeriana Colao, Elvira Tarsitano, Michele Camero, Michele Losurdo, Canio Buonavoglia & Maria Tempesta. (2012) A Caprine Herpesvirus 1 Vaccine Adjuvanted with MF59™ Protects against Vaginal Infection and Interferes with the Establishment of Latency in Goats. PLoS ONE 7:4, pages e34913.
Crossref
Antu K. Dey, Brian Burke, Yide Sun, Karin Hartog, Jonathan L. Heeney, David Montefiori, Indresh K. Srivastava & Susan W. Barnett. (2012) Use of a polyanionic carbomer, Carbopol971P, in combination with MF59, improves antibody responses to HIV-1 envelope glycoprotein. Vaccine 30:17, pages 2749-2759.
Crossref
J. Ruiz-Aragón, J.M. Molina Linde, R. Yang, S. Márquez-Peláez, P. Moya Cordero & R. Rodríguez López. (2012) Seguridad de la vacuna antigripal con el adyuvante MF59. Revisión sistemática de la literatura. Vacunas 13:2, pages 49-56.
Crossref
Steven G Reed, Christopher B Fox & Darrick CarterJennifer WhitakerNadine RouphaelMark J Mulligan. 2012. Emulsion-based Vaccine Adjuvants. Emulsion-based Vaccine Adjuvants 6 19 .
Marcin Kwissa, Helder I. Nakaya, Herold Oluoch & Bali Pulendran. (2012) Distinct TLR adjuvants differentially stimulate systemic and local innate immune responses in nonhuman primates. Blood 119:9, pages 2044-2055.
Crossref
Samantha Sayers, Guerlain Ulysse, Zuoshuang Xiang & Yongqun He. (2012) Vaxjo: A Web-Based Vaccine Adjuvant Database and Its Application for Analysis of Vaccine Adjuvants and Their Uses in Vaccine Development. Journal of Biomedicine and Biotechnology 2012, pages 1-13.
Crossref
Anna Smed-Sörensen & Karin Loré. 2013. HIV Interactions with Dendritic Cells. HIV Interactions with Dendritic Cells 263 288 .
Theodore F. TSAI. (2011) MF59<sup>®</sup> Adjuvanted Seasonal and Pandemic Influenza Vaccines. YAKUGAKU ZASSHI 131:12, pages 1733-1741.
Crossref
Rino Rappuoli, Christian W. Mandl, Steven Black & Ennio De Gregorio. (2011) Vaccines for the twenty-first century society. Nature Reviews Immunology 11:12, pages 865-872.
Crossref
Camilla Foged. (2011) Subunit vaccines of the future: the need for safe, customized and optimized particulate delivery systems. Therapeutic Delivery 2:8, pages 1057-1077.
Crossref
Theodore F. Tsai, Poh Lian Lim, Frank von Sonnenburg & Ralf Clemens. (2011) The Potential Utility of Adjuvanted Seasonal Influenza Vaccine for Travelers. Journal of Travel Medicine 18:4, pages 231-232.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.