15,225
Views
115
CrossRef citations to date
0
Altmetric
Editorial

ISCOM technology-based Matrix M™ adjuvant: success in future vaccines relies on formulation

, &
Pages 401-403 | Published online: 09 Jan 2014

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (12)

Eddie Underwood, Lisa M. Dunkle, Shabir A. Madhi, Cynthia L. Gay, Paul T. Heath, Karen L. Kotloff, Katherine Smith, Gordon Chau, Shirley Galbiati, Alice McGarry, Wayne Woo, Iksung Cho, Katia Alves, Germán Áñez, Chijioke Bennett, Vivek Shinde, Louis Fries, Raburn M. Mallory, Gregory M. Glenn & Seth Toback. (2023) Safety, efficacy, and immunogenicity of the NVX-CoV2373 vaccine. Expert Review of Vaccines 22:1, pages 501-517.
Read now
Shiza Malik, Khalid Muhammad, Sanaa Masood Aslam & Yasir Waheed. (2023) Tracing the recent updates on vaccination approaches and significant adjuvants being developed against HIV. Expert Review of Anti-infective Therapy 21:4, pages 431-446.
Read now
Linda Stertman, Anna-Karin E. Palm, Behdad Zarnegar, Berit Carow, Carolina Lunderius Andersson, Sofia E. Magnusson, Cecilia Carnrot, Vivek Shinde, Gale Smith, Gregory Glenn, Louis Fries & Karin Lövgren Bengtsson. (2023) The Matrix-M™ adjuvant: A critical component of vaccines for the 21st century. Human Vaccines & Immunotherapeutics 19:1.
Read now
Alvaro R. Escalante-Sansores, Angel E. Absalón & Diana V. Cortés-Espinosa. (2022) Improving immunogenicity of poultry vaccines by use of molecular adjuvants. World's Poultry Science Journal 78:3, pages 705-726.
Read now
Daniel Mekonnen, Hylemariam Mihiretie Mengist & Tengchuan Jin. (2022) SARS-CoV-2 subunit vaccine adjuvants and their signaling pathways. Expert Review of Vaccines 21:1, pages 69-81.
Read now
Xinyuan Zhang, Zhigang Zhang, Ningshao Xia & Qinjian Zhao. (2021) Carbohydrate-containing nanoparticles as vaccine adjuvants. Expert Review of Vaccines 20:7, pages 797-810.
Read now
Indranil Sarkar, Ravendra Garg & Sylvia van Drunen Littel-van den Hurk. (2019) Selection of adjuvants for vaccines targeting specific pathogens. Expert Review of Vaccines 18:5, pages 505-521.
Read now
Raj Kumar Singh, Kuldeep Dhama, Yashpal Singh Malik, Muthannan Andavar Ramakrishnan, Kumaragurubaran Karthik, Rekha Khandia, Ruchi Tiwari, Ashok Munjal, Mani Saminathan, Swati Sachan, Perumal Arumugam Desingu, Jobin Jose Kattoor, Hafiz M.N. Iqbal & Sunil Kumar Joshi. (2017) Ebola virus – epidemiology, diagnosis, and control: threat to humans, lessons learnt, and preparedness plans – an update on its 40 year's journey. Veterinary Quarterly 37:1, pages 98-135.
Read now
Karen A. Martins, Peter B. Jahrling, Sina Bavari & Jens H. Kuhn. (2016) Ebola virus disease candidate vaccines under evaluation in clinical trials. Expert Review of Vaccines 15:9, pages 1101-1112.
Read now
Karin Lövgren Bengtsson, Karin H Karlsson, Sofia E Magnusson, Jenny M Reimer & Linda Stertman. (2013) Matrix-M™ adjuvant: enhancing immune responses by ‘setting the stage’ for the antigen. Expert Review of Vaccines 12:8, pages 821-823.
Read now
Zahra Aryan, Enrico Comapalati, Giorgio Walter Canonica & Nima Rezaei. (2013) Allergen-specific immunotherapy in asthmatic children: from the basis to clinical applications. Expert Review of Vaccines 12:6, pages 639-659.
Read now
Teresa Cruz-Bustos, Gloria González-González, Julia Morales-Sanfrutos, Alicia Megía-Fernández, Francisco Santoyo-González & Antonio Osuna. (2012) Functionalization of immunostimulating complexes (ISCOMs) with lipid vinyl sulfones and their application in immunological techniques and therapy. International Journal of Nanomedicine 7, pages 5941-5956.
Read now

Articles from other publishers (103)

Adrián Plata & Alberto Fernández‐Tejada. 2023. Carbohydrate‐Based Therapeutics. Carbohydrate‐Based Therapeutics 73 110 .
Cecilia Carnrot, Berit Carow, Anna-Karin E. Palm, Eray Akpinar, Per-Henrik Helgesson, Ingrid Lekberg Osterman, Emelie Bringeland, Bryant Foreman, Nita Patel, Johan Bankefors, Louis Fries & Linda Stertman. (2023) Biodistribution of the saponin-based adjuvant Matrix-M™ following intramuscular injection in mice. Frontiers in Drug Delivery 3.
Crossref
Helmy WidyastutiSanarto SantosoSri WinarsihSri Poeranto. (2023) The Immunological Response of Salmonella typhi Protein Subunits (Outer Membrane Protein 36 kDa, Fimbriae 36 kDa, and Flagellin) as a Candidate for Oral Typhoid Vaccine. Research Journal of Pharmacy and Technology, pages 3891-3898.
Crossref
Sumin Han, Panjae Lee & Hyo-Jick Choi. (2023) Non-Invasive Vaccines: Challenges in Formulation and Vaccine Adjuvants. Pharmaceutics 15:8, pages 2114.
Crossref
Nataschja I Ho, Lisa G M Huis in 't Veld, Jesper van Eck van der Sluijs, Branco M H Heuts, Maaike W G Looman, Esther D Kers-Rebel, Koen van den Dries, Harry Dolstra, Joost H A Martens, Willemijn Hobo & Gosse J Adema. (2023) Saponin-based adjuvants enhance antigen cross-presentation in human CD11c + CD1c + CD5 − CD163 + conventional type 2 dendritic cells . Journal for ImmunoTherapy of Cancer 11:8, pages e007082.
Crossref
Wandi Zhu, Jaeyoung Park, Thomas Pho, Lai Wei, Chunhong Dong, Joo Kim, Yao Ma, Julie A. Champion & Bao‐Zhong Wang. (2023) ISCOMs/MPLA‐Adjuvanted SDAD Protein Nanoparticles Induce Improved Mucosal Immune Responses and Cross‐Protection in Mice. Small 19:34.
Crossref
Javier Villarraza, Antonela Fuselli, Agustina Gugliotta, Ernesto Garay, María Celeste Rodríguez, Diego Fontana, Sebastián Antuña, Victoria Gastaldi, Juan Manuel Battagliotti, María Belén Tardivo, Diego Alvarez, Eliana Castro, Juliana Cassataro, Natalia Ceaglio & Claudio Prieto. (2023) A COVID-19 vaccine candidate based on SARS-CoV-2 spike protein and immune-stimulating complexes. Applied Microbiology and Biotechnology 107:11, pages 3429-3441.
Crossref
Radhika Thanvi, Shadia Nada, Ravindika Dissanayake, Abhishek Vartak, Chloé Olayinka Sebilleau, Nur-E Alom, Erin G. Prestwich, Katherine A. Wall & Steven J. Sucheck. (2023) Synthesis and Evaluation of a Self-Adjuvanting Pseudomonal Vaccine Based on Major Outer Membrane Porin OprF Epitopes Formulated with Low-Toxicity QS-21-Containing Liposomes. Bioconjugate Chemistry 34:5, pages 893-910.
Crossref
Ivan S. Pires, Kaiyuan Ni, Mariane Bandeira Melo, Na Li, Elana Ben-Akiva, Laura Maiorino, Jonathan Dye, Kristen A. Rodrigues, DongSoo Yun, Byungji Kim, Ryan R. Hosn, Paula T. Hammond & Darrell J. Irvine. (2023) Controlled lipid self-assembly for scalable manufacturing of next-generation immune stimulating complexes. Chemical Engineering Journal 464, pages 142664.
Crossref
Javier Castrodeza-Sanz, Iván Sanz-Muñoz & Jose M. Eiros. (2023) Adjuvants for COVID-19 Vaccines. Vaccines 11:5, pages 902.
Crossref
Kai Chen, Ning Wang, Xiaomin Zhang, Meng Wang, Yanyu Liu & Yun Shi. (2023) Potentials of saponins-based adjuvants for nasal vaccines. Frontiers in Immunology 14.
Crossref
Fuhua Wu, Ming Qin, Hairui Wang & Xun Sun. (2022) Nanovaccines to combat virus‐related diseases. WIREs Nanomedicine and Nanobiotechnology 15:2.
Crossref
Xinyuan Chen. (2023) Emerging adjuvants for intradermal vaccination. International Journal of Pharmaceutics 632, pages 122559.
Crossref
Nathalie Garçon & Martin Friede. 2023. Plotkin's Vaccines. Plotkin's Vaccines 77 90.e4 .
Charles Mulamba, Chris Williams, Katharina Kreppel, Jean Bosco Ouedraogo & Ally I. Olotu. (2022) Evaluation of the Pfs25-IMX313/Matrix-M malaria transmission-blocking candidate vaccine in endemic settings. Malaria Journal 21:1.
Crossref
Claudia A Daubenberger & Gemma Moncunill. (2022) Next-generation malaria subunit vaccines to reduce disease burden in African children. The Lancet Infectious Diseases 22:12, pages 1655-1656.
Crossref
Giuliana A. Lupi, Florencia X. Santiago Valtierra, Gabriel Cabrera, Roque Spinelli, Álvaro S. Siano, Verónica González, Antonio Osuna, Gerardo M. Oresti & Iván Marcipar. (2022) Development of low-cost cage-like particles to formulate veterinary vaccines. Veterinary Immunology and Immunopathology 251, pages 110460.
Crossref
Sneha Ratnapriya, Eva Perez‐Greene, Luca Schifanella & Alon Herschhorn. (2021) Adjuvant‐mediated enhancement of the immune response to HIV vaccines. The FEBS Journal 289:12, pages 3317-3334.
Crossref
Mark B. Carascal, Rance Derrick N. Pavon & Windell L. Rivera. (2022) Recent Progress in Recombinant Influenza Vaccine Development Toward Heterosubtypic Immune Response. Frontiers in Immunology 13.
Crossref
Alexander Domnich, Andrea Orsi, Carlo-Simone Trombetta, Giulia Guarona, Donatella Panatto & Giancarlo Icardi. (2022) COVID-19 and Seasonal Influenza Vaccination: Cross-Protection, Co-Administration, Combination Vaccines, and Hesitancy. Pharmaceuticals 15:3, pages 322.
Crossref
Dumar Alexander Jaramillo-Hernández, Luis Fabián Salazar Garcés, Luis Gustavo Carvalho Pacheco, Carina Silva Pinheiro & Neuza Maria Alcantara-Neves. (2022) Protective response mediated by immunization with recombinant proteins in a murine model of toxocariasis and canine infection by Toxocara canis. Vaccine 40:6, pages 912-923.
Crossref
Julieta Sandra CUEVAS-ROMERO, José Luis CERRITEÑO-SÁNCHEZ, Rocío LARA-ROMERO, Marco Antonio VEGA-LÓPEZ, Carmen RAMÍREZ-ESTUDILLO, Humberto RAMÍREZ-MENDOZA, Mikael BERG & Karin LÖVGREN-BENGTSSON. (2022) Immunogenicity of a recombinant hemagglutinin neuraminidase-<i>Porcine rubulavirus</i> produced by <i>Escherichia coli</i> of <i>Porcine rubulavirus</i> gives protective immunity of litter after challenge. Journal of Veterinary Medical Science 84:12, pages 1595-1604.
Crossref
Sheyda Ranjbar, Yousef Fatahi & Fatemeh Atyabi. (2022) The quest for a better fight: How can nanomaterials address the current therapeutic and diagnostic obstacles in the fight against COVID-19?. Journal of Drug Delivery Science and Technology 67, pages 102899.
Crossref
Bassel Akache, Felicity C. Stark, Gerard Agbayani, Tyler M. Renner & Michael J. McCluskie. 2022. Vaccine Design. Vaccine Design 179 231 .
Murillo Silva, Yu Kato, Mariane B. Melo, Ivy Phung, Brian L. Freeman, Zhongming LiKangsan Roh, Jan W. Van Wijnbergen, Hannah WatkinsChiamaka A. EnemuoBrittany L. Hartwell, Jason Y. H. Chang, Shuhao Xiao, Kristen A. Rodrigues, Kimberly M. CirelliNa LiSonya Haupt, Aereas Aung, Benjamin CossetteWuhbet AbrahamSwati Kataria, Raiza BastidasJinal Bhiman, Caitlyn Linde, Nathaniel I. Bloom, Bettina Groschel, Erik Georgeson, Nicole Phelps, Ayush Thomas, Julia Bals, Diane G. CarnathanDaniel Lingwood, Dennis R. Burton, Galit Alter, Timothy P. Padera, Angela M. Belcher, William R. Schief, Guido Silvestri, Ruth M. RuprechtShane Crotty & Darrell J. Irvine. (2021) A particulate saponin/TLR agonist vaccine adjuvant alters lymph flow and modulates adaptive immunity. Science Immunology 6:66.
Crossref
Fan Zhou, Lena Hansen, Gabriel Pedersen, Gunnveig Grødeland & Rebecca Cox. (2021) Matrix M Adjuvanted H5N1 Vaccine Elicits Broadly Neutralizing Antibodies and Neuraminidase Inhibiting Antibodies in Humans That Correlate With In Vivo Protection. Frontiers in Immunology 12.
Crossref
Matilde Durán-Lobato, Ana María López-Estévez, Ana Sara Cordeiro, Tamara G. Dacoba, José Crecente-Campo, Dolores Torres & María José Alonso. (2021) Nanotechnologies for the delivery of biologicals: Historical perspective and current landscape. Advanced Drug Delivery Reviews 176, pages 113899.
Crossref
Yasunari Haseda, Lisa Munakata, Chiyo Kimura, Yumi Kinugasa-Katayama, Yasuko Mori, Ryo Suzuki & Taiki Aoshi. (2021) Development of combination adjuvant for efficient T cell and antibody response induction against protein antigen. PLOS ONE 16:8, pages e0254628.
Crossref
Sakineh Pirahmadi, Sedigheh Zakeri, Navid D. Djadid & Akram A. Mehrizi. (2021) A review of combination adjuvants for malaria vaccines: a promising approach for vaccine development. International Journal for Parasitology 51:9, pages 699-717.
Crossref
Sofia B. Carvalho, Cristina Peixoto, Manuel J. T. Carrondo & Ricardo J. S. Silva. (2021) Downstream processing for influenza vaccines and candidates: An update. Biotechnology and Bioengineering 118:8, pages 2845-2869.
Crossref
Chunxi Zeng, Xucheng Hou, Margaret Bohmer & Yizhou Dong. (2021) Advances of nanomaterials‐based strategies for fighting against COVID‐19. VIEW 2:4.
Crossref
Rekha R. Rapaka, Alan S. Cross & Monica A. McArthur. (2021) Using Adjuvants to Drive T Cell Responses for Next-Generation Infectious Disease Vaccines. Vaccines 9:8, pages 820.
Crossref
Mengdie Li, Lisa M. Kaminskas & Nirmal Marasini. (2021) Recent advances in nano/microparticle-based oral vaccines. Journal of Pharmaceutical Investigation 51:4, pages 425-438.
Crossref
Pengfei Wang. (2021) Natural and Synthetic Saponins as Vaccine Adjuvants. Vaccines 9:3, pages 222.
Crossref
Zhuofan Li, Yiwen Zhao, Yibo Li & Xinyuan Chen. (2021) Adjuvantation of Influenza Vaccines to Induce Cross-Protective Immunity. Vaccines 9:2, pages 75.
Crossref
Wandi Zhu, Chunhong Dong, Lai Wei & Bao-Zhong Wang. (2021) Promising Adjuvants and Platforms for Influenza Vaccine Development. Pharmaceutics 13:1, pages 68.
Crossref
Mohamed H. Houta, Olusegun O. Awe & Ahmed Ali. (2021) Infection with Avian Coronaviruses: A recurring problem in turkeys. German Journal of Veterinary Research 1:3, pages 19-27.
Crossref
Jessica Molina-Franky, Laura Cuy-Chaparro, Anny Camargo, César Reyes, Marcela Gómez, David Ricardo Salamanca, Manuel Alfonso Patarroyo & Manuel Elkin Patarroyo. (2020) Plasmodium falciparum pre-erythrocytic stage vaccine development. Malaria Journal 19:1.
Crossref
Juine-Ruey Chen, Yo-Min Liu, Yung-Chieh Tseng & Che Ma. (2020) Better influenza vaccines: an industry perspective. Journal of Biomedical Science 27:1.
Crossref
Diego Fontana, Federico Marsili, Marina Etcheverrigaray, Ricardo Kratje & Claudio Prieto. (2020) Rabies VLPs adjuvanted with saponin-based liposomes induce enhanced immunogenicity mediated by neutralizing antibodies in cattle, dogs and cats. Journal of Virological Methods 286, pages 113966.
Crossref
C. Campos-Estrada, B. Riquelme, M. Vergara, C. Altamirano & M.F. Cavieres. (2020) In vitro Notch-mediated adjuvant immunogenic potency is induced by combining QS-21 and MPL in a co-culture model of PBMC and HUVEC cells. Toxicology in Vitro 68, pages 104947.
Crossref
Asmita Banstola, Jee-Heon Jeong & Simmyung Yook. (2020) Immunoadjuvants for cancer immunotherapy: A review of recent developments. Acta Biomaterialia 114, pages 16-30.
Crossref
Etsuro Nanishi, David J. Dowling & Ofer Levy. (2020) Toward precision adjuvants: optimizing science and safety. Current Opinion in Pediatrics 32:1, pages 125-138.
Crossref
Atin Khalaj‐Hedayati, Caroline Lin Lin Chua, Peter Smooker & Khai Wooi Lee. (2019) Nanoparticles in influenza subunit vaccine development: Immunogenicity enhancement. Influenza and Other Respiratory Viruses 14:1, pages 92-101.
Crossref
Pragya Misra & Shailza Singh. 2020. Systems and Synthetic Immunology. Systems and Synthetic Immunology 1 52 .
Thomas Ebensen, Barbara Fuchs, Kai Schulze & Carlos Alberto Guzmán. 2020. Health Consequences of Microbial Interactions with Hydrocarbons, Oils, and Lipids. Health Consequences of Microbial Interactions with Hydrocarbons, Oils, and Lipids 285 315 .
R R C New. (2019) Formulation technologies for oral vaccines. Clinical and Experimental Immunology 198:2, pages 153-169.
Crossref
Jorge A. Soto, Diego A. Diaz-Dinamarca, Daniel A. Soto, Magaly J. Barrientos, Flavio Carrión, Alexis M. Kalergis & Abel E. Vasquez. (2019) Cellular immune response induced by surface immunogenic protein with AbISCO-100 adjuvant vaccination decreases group B Streptococcus vaginal colonization. Molecular Immunology 111, pages 198-204.
Crossref
Yve VS Magedans, Anna CA Yendo, Fernanda de Costa, Grace Gosmann & Arthur G Fett-Neto. (2019) Foamy matters: an update on Quillaja saponins and their use as immunoadjuvants . Future Medicinal Chemistry 11:12, pages 1485-1499.
Crossref
Chioma Miracle Ojiako, Ebere Innocent Okoye, Angus Nnamdi Oli, Chibueze Jeremiah Ike, Charles O. Esimone & Anthony A. Attama. (2019) Preliminary studies on the formulation of immune stimulating complexes using saponin from Carica papaya leaves. Heliyon 5:6, pages e01962.
Crossref
Ayman Mubarak, Wael Alturaiki & Maged Gomaa Hemida. (2019) Middle East Respiratory Syndrome Coronavirus (MERS-CoV): Infection, Immunological Response, and Vaccine Development. Journal of Immunology Research 2019, pages 1-11.
Crossref
T. A. Kuznetsova, E. V. Persiyanova, T. S. Zaporozhets & N. N. Besednova. (2019) ADJUVANTS OF INFLUENZA VACCINES: NEW POSSIBILITIES OF USING SULPHATED POLYSACCHARIDES FROM MARINE BROWN ALGAE. Problems of Virology 64:1, pages 5-11.
Crossref
Thomas Ebensen, Barbara Fuchs, Kai Schulze & Carlos Alberto Guzmán. 2018. Health Consequences of Microbial Interactions with Hydrocarbons, Oils, and Lipids. Health Consequences of Microbial Interactions with Hydrocarbons, Oils, and Lipids 1 31 .
Ting Liu, Rui Qian, Qingchuan Liu, Tingni Wu & Jialong Chen. 2018. Immunization - Vaccine Adjuvant Delivery System and Strategies. Immunization - Vaccine Adjuvant Delivery System and Strategies.
Arnaud Chêne, Stéphane Gangnard, Célia Dechavanne, Sebastien Dechavanne, Anand Srivastava, Marilou Tétard, Sophia Hundt, Odile Leroy, Nicolas Havelange, Nicola K. Viebig & Benoît Gamain. (2018) Down-selection of the VAR2CSA DBL1-2 expressed in E. coli as a lead antigen for placental malaria vaccine development. npj Vaccines 3:1.
Crossref
Bernt Hjertner, Theresa Bengtsson, Bror Morein, Staffan Paulie & Caroline Fossum. (2018) A novel adjuvant G3 induces both Th1 and Th2 related immune responses in mice after immunization with a trivalent inactivated split-virion influenza vaccine. Vaccine 36:23, pages 3340-3344.
Crossref
Anmol Chandele. (2018) New Technologies for Vaccine Development: Harnessing the Power of Human Immunology. Journal of the Indian Institute of Science 98:1, pages 33-47.
Crossref
Nathalie Garçon & Martin Friede. 2018. Plotkin's Vaccines. Plotkin's Vaccines 61 74.e4 .
Rakesh Bastola, Gyubin Noh, Taekwang Keum, Santosh Bashyal, Jo-Eun Seo, Jaewoong Choi, Yeonsu Oh, YoungSik Cho & Sangkil Lee. (2017) Vaccine adjuvants: smart components to boost the immune system. Archives of Pharmacal Research 40:11, pages 1238-1248.
Crossref
A F Altenburg, S E Magnusson, F Bosman, L Stertman, R D de Vries & G F Rimmelzwaan. (2017) Protein and modified vaccinia virus Ankara-based influenza virus nucleoprotein vaccines are differentially immunogenic in BALB/c mice. Clinical and Experimental Immunology 190:1, pages 19-28.
Crossref
Daiana Bertona, Nazarena Pujato, Iván Bontempi, Verónica Gonzalez, Gabriel Cabrera, Luis Gugliotta, Daniela Hozbor, Alcides Nicastro, Luis Calvinho & Iván Sergio Marcipar. (2017) Development and assessment of a new cage-like particle adjuvant. Journal of Pharmacy and Pharmacology 69:10, pages 1293-1303.
Crossref
Gale Smith, Ye Liu, David Flyer, Michael J. Massare, Bin Zhou, Nita Patel, Larry Ellingsworth, Maggie Lewis, James F. Cummings & Greg Glenn. (2017) Novel hemagglutinin nanoparticle influenza vaccine with Matrix-M™ adjuvant induces hemagglutination inhibition, neutralizing, and protective responses in ferrets against homologous and drifted A(H3N2) subtypes. Vaccine 35:40, pages 5366-5372.
Crossref
Srinivasa Reddy Bonam, Charalambos D. Partidos, Sampath Kumar M. Halmuthur & Sylviane Muller. (2017) An Overview of Novel Adjuvants Designed for Improving Vaccine Efficacy. Trends in Pharmacological Sciences 38:9, pages 771-793.
Crossref
Christopher M. Coleman, Thiagarajan Venkataraman, Ye V. Liu, Gregory M. Glenn, Gale E. Smith, David C. Flyer & Matthew B. Frieman. (2017) MERS-CoV spike nanoparticles protect mice from MERS-CoV infection. Vaccine 35:12, pages 1586-1589.
Crossref
Nina Sanina, Natalia Chopenko, Andrey Mazeika & Eduard Kostetsky. (2017) Nanoparticulate Tubular Immunostimulating Complexes: Novel Formulation of Effective Adjuvants and Antigen Delivery Systems. BioMed Research International 2017, pages 1-9.
Crossref
Julieta Sandra Cuevas-Romero, José Francisco Rivera-Benítez, Eliseo Hernández-Baumgarten, Pablo Hernández-Jaúregui, Marco Vega, Anne-Lie Blomström, Mikael Berg & Claudia Baule. (2016) Cloning, expression and characterization of potential immunogenic recombinant hemagglutinin-neuraminidase protein of Porcine rubulavirus. Protein Expression and Purification 128, pages 1-7.
Crossref
Martijn H. den Brok, Christian Büll, Melissa Wassink, Annemarie M. de Graaf, Jori A. Wagenaars, Marthe Minderman, Mayank Thakur, Sebastian Amigorena, Eric O. Rijke, Carla C. Schrier & Gosse J. Adema. (2016) Saponin-based adjuvants induce cross-presentation in dendritic cells by intracellular lipid body formation. Nature Communications 7:1.
Crossref
Hege Lund, Preben Boysen, Caroline Piercey Åkesson, Anna Monika Lewandowska-Sabat & Anne K. Storset. (2016) Transient Migration of Large Numbers of CD14++ CD16+ Monocytes to the Draining Lymph Node after Onset of Inflammation. Frontiers in Immunology 7.
Crossref
Emilia Bigaeva, Eva van Doorn, Heng Liu & Eelko Hak. (2016) Meta-Analysis on Randomized Controlled Trials of Vaccines with QS-21 or ISCOMATRIX Adjuvant: Safety and Tolerability. PLOS ONE 11:5, pages e0154757.
Crossref
Vasso Apostolopoulos. (2016) Vaccine Delivery Methods into the Future. Vaccines 4:2, pages 9.
Crossref
Samuel Paulo Cibulski, Gustavo Mourglia-Ettlin, Thais Fumaco Teixeira, Lenora Quirici, Paulo Michel Roehe, Fernando Ferreira & Fernando Silveira. (2016) Novel ISCOMs from Quillaja brasiliensis saponins induce mucosal and systemic antibody production, T-cell responses and improved antigen uptake. Vaccine 34:9, pages 1162-1171.
Crossref
Ana S Cordeiro & María J Alonso. (2016) Recent advances in vaccine delivery. Pharmaceutical Patent Analyst 5:1, pages 49-73.
Crossref
Robyn Marty-Roix, Gregory I. Vladimer, Kimberly Pouliot, Dan Weng, Rachel Buglione-Corbett, Kim West, John D. MacMicking, Jonathan D. Chee, Shixia Wang, Shan Lu & Egil Lien. (2016) Identification of QS-21 as an Inflammasome-activating Molecular Component of Saponin Adjuvants. Journal of Biological Chemistry 291:3, pages 1123-1136.
Crossref
Ankur Gupta, Soumen Das, Brian Schanen & Sudipta Seal. (2015) Adjuvants in micro‐ to nanoscale: current state and future direction. WIREs Nanomedicine and Nanobiotechnology 8:1, pages 61-84.
Crossref
Freek Cox, Eirikur Saeland, Matthijs Baart, Martin Koldijk, Jeroen Tolboom, Liesbeth Dekking, Wouter Koudstaal, Karin Lövgren Bengtsson, Jaap Goudsmit & Katarina Radošević. (2015) Matrix-M™ adjuvation broadens protection induced by seasonal trivalent virosomal influenza vaccine. Virology Journal 12:1.
Crossref
Freek Cox, Anna Roos, Nicole Hafkemeijer, Matthijs Baart, Jeroen Tolboom, Liesbeth Dekking, Koert Stittelaar, Jaap Goudsmit, Katarina Radošević & Eirikur Saeland. (2015) Matrix-M Adjuvated Seasonal Virosomal Influenza Vaccine Induces Partial Protection in Mice and Ferrets against Avian H5 and H7 Challenge. PLOS ONE 10:9, pages e0135723.
Crossref
Rebecca J. Cox, Diane Major, Gabriel Pedersen, Rishi D. Pathirana, Katja Hoschler, Kate Guilfoyle, Sarah Roseby, Geir Bredholt, Jörg Assmus, Lucy Breakwell, Laura Campitelli & Haakon Sjursen. (2015) Matrix M H5N1 Vaccine Induces Cross-H5 Clade Humoral Immune Responses in a Randomized Clinical Trial and Provides Protection from Highly Pathogenic Influenza Challenge in Ferrets. PLOS ONE 10:7, pages e0131652.
Crossref
Paola Martinez, Christopher Sundling, Sijy O'Dell, John R. Mascola, Richard T. Wyatt & Gunilla B. Karlsson Hedestam. (2015) Primate immune responses to HIV-1 Env formulated in the saponin-based adjuvant AbISCO-100 in the presence or absence of TLR9 co-stimulation. Scientific Reports 5:1.
Crossref
Sujin LeeMinh Trang Nguyen. (2015) Recent Advances of Vaccine Adjuvants for Infectious Diseases. Immune Network 15:2, pages 51.
Crossref
Hanne M. Nielsen, Henriette B. Hübschmann & Thomas Rades. 2015. Subunit Vaccine Delivery. Subunit Vaccine Delivery 141 158 .
Petra Riedl, Michael Reiser, Katja Stifter, Jana Krieger & Reinhold Schirmbeck. (2014) Differential presentation of endogenous and exogenous hepatitis B surface antigens influences priming of CD8 + T cells in an epitope-specific manner . European Journal of Immunology 44:7, pages 1981-1991.
Crossref
Qiyan Xiong, Yanna Wei, Haidong Xie, Zhixin Feng, Yuan Gan, Chunlai Wang, Maojun Liu, Fangfang Bai, Fang Xie & Guoqing Shao. (2014) Effect of different adjuvant formulations on the immunogenicity and protective effect of a live Mycoplasma hyopneumoniae vaccine after intramuscular inoculation. Vaccine 32:27, pages 3445-3451.
Crossref
Christopher M. Coleman, Ye V. Liu, Haiyan Mu, Justin K. Taylor, Michael Massare, David C. Flyer, Gregory M. Glenn, Gale E. Smith & Matthew B. Frieman. (2014) Purified coronavirus spike protein nanoparticles induce coronavirus neutralizing antibodies in mice. Vaccine 32:26, pages 3169-3174.
Crossref
Christine Sund Lundström, Anna Mattsson, Karin Lövgren, Åsa Eriksson, Åsa Liljegren Sundberg, Mats Lundgren & Camilla Estmer Nilsson. (2014) Sensitive methods for evaluation of antibodies for host cell protein analysis and screening of impurities in a vaccine process. Vaccine 32:24, pages 2911-2915.
Crossref
M. Noia, B. Domínguez, J. Leiro, J. Blanco-Méndez, A. Luzardo-Álvarez & J. Lamas. (2014) Inflammatory responses and side effects generated by several adjuvant-containing vaccines in turbot. Fish & Shellfish Immunology 38:1, pages 244-254.
Crossref
Benoît Levast, Sunita Awate, Lorne Babiuk, George Mutwiri, Volker Gerdts & Sylvia van Drunen Littel-van den Hurk. (2014) Vaccine Potentiation by Combination Adjuvants. Vaccines 2:2, pages 297-322.
Crossref
Joseph P. Nkolola, Ann Cheung, James R. Perry, Darrick Carter, Steve Reed, Hanneke Schuitemaker, Maria Grazia Pau, Michael S. Seaman, Bing Chen & Dan H. Barouch. (2014) Comparison of multiple adjuvants on the stability and immunogenicity of a clade C HIV-1 gp140 trimer. Vaccine 32:18, pages 2109-2116.
Crossref
Tomonori Somamoto, Erling Olaf Koppang & Uwe Fischer. (2014) Antiviral functions of CD8+ cytotoxic T cells in teleost fish. Developmental & Comparative Immunology 43:2, pages 197-204.
Crossref
Jenna Anderson, Emmanuel Bréard, Karin Lövgren Bengtsson, Kjell-Olov Grönvik, Stéphan Zientara, Jean-Francois Valarcher & Sara Hägglund. (2014) Purification, Stability, and Immunogenicity Analyses of Five Bluetongue Virus Proteins for Use in Development of a Subunit Vaccine That Allows Differentiation of Infected from Vaccinated Animals. Clinical and Vaccine Immunology 21:3, pages 443-452.
Crossref
Caroline Fossum, Bernt Hjertner, Viktor Ahlberg, Wasin Charerntantanakul, Kathy McIntosh, Lisbeth Fuxler, Navisraj Balagunaseelan, Per Wallgren & Karin Lövgren Bengtsson. (2014) Early inflammatory response to the saponin adjuvant Matrix-M in the pig. Veterinary Immunology and Immunopathology 158:1-2, pages 53-61.
Crossref
Qiyan Xiong, Yanna Wei, Zhixin Feng, Yuan Gan, Zhanjun Liu, Maojun Liu, Fangfang Bai & Guoqing Shao. (2014) Protective efficacy of a live attenuated Mycoplasma hyopneumoniae vaccine with an ISCOM-matrix adjuvant in pigs. The Veterinary Journal 199:2, pages 268-274.
Crossref
Y.P. Hecker, D.P. Moore, V. Quattrocchi, J. Regidor-Cerrillo, A. Verna, M.R. Leunda, E. Morrell, L.M. Ortega-Mora, P. Zamorano, M.C. Venturini & C.M. Campero. (2013) Immune response and protection provided by live tachyzoites and native antigens from the NC-6 Argentina strain of Neospora caninum in pregnant heifers. Veterinary Parasitology 197:3-4, pages 436-446.
Crossref
Feng-Shan Gao, Lei Feng, Qiang Zhang, Ruo-qian Yan, Yun-Gang Li & Xin-sheng Li. (2013) Immunogenicity of Two FMDV Nonameric Peptides Encapsulated in Liposomes in Mice and the Protective Efficacy in Guinea Pigs. PLoS ONE 8:7, pages e68658.
Crossref
Hoang T. Phan, Julia Pohl, Doreen M. Floss, Frank Rabenstein, Jutta Veits, Binh T. Le, Ha H. Chu, Gerd Hause, Thomas Mettenleiter & Udo Conrad. (2013) ELP ylated haemagglutinins produced in tobacco plants induce potentially neutralizing antibodies against H5N 1 viruses in mice . Plant Biotechnology Journal 11:5, pages 582-593.
Crossref
Mojca Skoberne, Rhonda Cardin, Alexander Lee, Ana Kazimirova, Veronica Zielinski, Danielle Garvie, Amy Lundberg, Shane Larson, Fernando J. Bravo, David I. Bernstein, Jessica B. Flechtner & Deborah Long. (2013) An Adjuvanted Herpes Simplex Virus 2 Subunit Vaccine Elicits a T Cell Response in Mice and Is an Effective Therapeutic Vaccine in Guinea Pigs. Journal of Virology 87:7, pages 3930-3942.
Crossref
Nathalie. Garçon, Stanley. Hem & Martin. Friede. 2013. Vaccines. Vaccines 58 70 .
Karin Lövgren Bengtsson. 2013. Novel Immune Potentiators and Delivery Technologies for Next Generation Vaccines. Novel Immune Potentiators and Delivery Technologies for Next Generation Vaccines 309 320 .
Viktor Ahlberg, Karin Lövgren Bengtsson, Per Wallgren & Caroline Fossum. (2012) Global transcriptional response to ISCOM-Matrix adjuvant at the site of administration and in the draining lymph node early after intramuscular injection in pigs. Developmental & Comparative Immunology 38:1, pages 17-26.
Crossref
Jenny M. Reimer, Karin H. Karlsson, Karin Lövgren-Bengtsson, Sofia E. Magnusson, Alexis Fuentes & Linda Stertman. (2012) Matrix-M™ Adjuvant Induces Local Recruitment, Activation and Maturation of Central Immune Cells in Absence of Antigen. PLoS ONE 7:7, pages e41451.
Crossref
Carl R Alving, Kristina K Peachman, Mangala Rao & Steven G Reed. (2012) Adjuvants for human vaccines. Current Opinion in Immunology 24:3, pages 310-315.
Crossref
Florencia Celeste Mansilla, Olga Lucía Franco-Mahecha, María Ángeles Lavoria, Dadín Prando Moore, Adrián Nicolás Giraldez, Marcela Elvira Iglesias, Maximiliano Wilda & Alejandra Victoria Capozzo. (2012) The immune enhancement of a novel soy lecithin/β-glucans based adjuvant on native Neospora caninum tachyzoite extract vaccine in mice. Vaccine 30:6, pages 1124-1131.
Crossref
Joseph G. Altin. 2012. Innovation in Vaccinology. Innovation in Vaccinology 135 178 .
Rebecca J. Cox, Gabriel Pedersen, Abdullah S. Madhun, Signe Svindland, Marianne Sævik, Lucy Breakwell, Katja Hoschler, Marieke Willemsen, Laura Campitelli, Jane Kristin Nøstbakken, Gerrit Jan Weverling, Jaco Klap, Kenneth C. McCullough, Maria Zambon, Ronald Kompier & Haakon Sjursen. (2011) Evaluation of a virosomal H5N1 vaccine formulated with Matrix M™ adjuvant in a phase I clinical trial. Vaccine 29:45, pages 8049-8059.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.