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Vaccine Profile

The RTS,S vaccine candidate for malaria

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Pages 589-599 | Published online: 09 Jan 2014

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Raiden B. Hasegawa & Dylan S. Small. (2022) Estimating Malaria Vaccine Efficacy in the Absence of a Gold Standard Case Definition: Mendelian Factorial Design. Journal of the American Statistical Association 117:539, pages 1466-1481.
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Rahul Shukla, Viswanathan Ramasamy, Ravi Kant Rajpoot, Upasana Arora, Ankur Poddar, Richa Ahuja, Hemalatha Beesetti, Sathyamangalam Swaminathan & Navin Khanna. (2019) Next generation designer virus-like particle vaccines for dengue. Expert Review of Vaccines 18:2, pages 105-117.
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Pascale Vandoolaeghe & Lode Schuerman. (2016) The RTS,S/AS01 malaria vaccine in children 5 to 17 months of age at first vaccination. Expert Review of Vaccines 15:12, pages 1481-1493.
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Geert Leroux-Roels, Isabel Leroux-Roels, Frédéric Clement, Opokua Ofori-Anyinam, Marc Lievens, Erik Jongert, Philippe Moris, W Ripley Ballou & Joe Cohen. (2014) Evaluation of the immune response to RTS,S/AS01 and RTS,S/AS02 adjuvanted vaccines. Human Vaccines & Immunotherapeutics 10:8, pages 2211-2219.
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Anton Beletskii, Ashley Galloway, Shyam Rele, Michele Stone & Frank Malinoski. (2014) Engineered PRINT® nanoparticles for controlled delivery of antigens and immunostimulants. Human Vaccines & Immunotherapeutics 10:7, pages 1908-1913.
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Christopher B Fox & Jean Haensler. (2013) An update on safety and immunogenicity of vaccines containing emulsion-based adjuvants. Expert Review of Vaccines 12:7, pages 747-758.
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Serena Tschan, Peter G Kremsner & Benjamin Mordmüller. (2012) Emerging drugs for malaria. Expert Opinion on Emerging Drugs 17:3, pages 319-333.
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Mark J Geels, Egeruan B Imoukhuede, Nathalie Imbault, Harry van Schooten, Terry McWade, Marita Troye-Blomberg, Roland Dobbelaer, Alister G Craig & Odile Leroy. (2011) European Vaccine Initiative: lessons from developing malaria vaccines. Expert Review of Vaccines 10:12, pages 1697-1708.
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Eleanor Barnes & Andrew J Pollard. (2011) Vaccines in clinical trials: infectious disease. Expert Review of Vaccines 10:5, pages 555-557.
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Robert K. M. Choy, A. Louis Bourgeois, Christian F. Ockenhouse, Richard I. Walker, Rebecca L. Sheets & Jorge Flores. (2022) Controlled Human Infection Models To Accelerate Vaccine Development. Clinical Microbiology Reviews 35:3.
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Ian W. Hamley. (2022) Peptides for Vaccine Development. ACS Applied Bio Materials 5:3, pages 905-944.
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Jishnu Das, Jonathan K. Fallon, Timothy C. Yu, Ashlin Michell, Todd J. Suscovich, Caitlyn Linde, Harini Natarajan, Joshua Weiner, Margherita Coccia, Scott Gregory, Margaret E. Ackerman, Elke Bergmann-Leitner, Laura Fontana, Sheetij Dutta, Douglas A. Lauffenburger, Erik Jongert, Ulrike Wille-Reece & Galit Alter. (2021) Delayed fractional dosing with RTS,S/AS01 improves humoral immunity to malaria via a balance of polyfunctional NANP6- and Pf16-specific antibodies. Med 2:11, pages 1269-1286.e9.
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Sakineh Pirahmadi, Sedigheh Zakeri, Navid D. Djadid & Akram A. Mehrizi. (2021) A review of combination adjuvants for malaria vaccines: a promising approach for vaccine development. International Journal for Parasitology 51:9, pages 699-717.
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Dongmei Cun, Chengqian Zhang, Hriday Bera & Mingshi Yang. (2021) Particle engineering principles and technologies for pharmaceutical biologics. Advanced Drug Delivery Reviews 174, pages 140-167.
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Mehreen S Datoo, Magloire H Natama, Athanase Somé, Ousmane Traoré, Toussaint Rouamba, Duncan Bellamy, Prisca Yameogo, Daniel Valia, Moubarak Tegneri, Florence Ouedraogo, Rachidatou Soma, Seydou Sawadogo, Faizatou Sorgho, Karim Derra, Eli Rouamba, Benedict Orindi, Fernando Ramos Lopez, Amy Flaxman, Federica Cappuccini, Reshma Kailath, Sean Elias, Ekta Mukhopadhyay, Andres Noe, Matthew Cairns, Alison Lawrie, Rachel Roberts, Innocent Valéa, Hermann Sorgho, Nicola Williams, Gregory Glenn, Louis Fries, Jenny Reimer, Katie J Ewer, Umesh Shaligram, Adrian V S Hill & Halidou Tinto. (2021) Efficacy of a low-dose candidate malaria vaccine, R21 in adjuvant Matrix-M, with seasonal administration to children in Burkina Faso: a randomised controlled trial. The Lancet 397:10287, pages 1809-1818.
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Rebeca T. Stiepel, Cole J. Batty, Christopher A. MacRaild, Raymond S. Norton, Eric Bachelder & Kristy M. Ainslie. (2021) Merozoite surface protein 2 adsorbed onto acetalated dextran microparticles for malaria vaccination. International Journal of Pharmaceutics 593, pages 120168.
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Diego A. Espinosa, Dennis Christensen, Christian Muñoz, Sanjay Singh, Emily Locke, Peter Andersen & Fidel Zavala. (2017) Robust antibody and CD8+ T-cell responses induced by P. falciparum CSP adsorbed to cationic liposomal adjuvant CAF09 confer sterilizing immunity against experimental rodent malaria infection. npj Vaccines 2:1.
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James G. KublinSebastian A. MikolajczakBrandon K. SackMatt E. FishbaugherAnnette SeilieLisa SheltonTracie VonGoedertMelike FiratSara MageeEmma FritzenWill BetzHeather S. KainDorender A. DankwaRyan W. J. SteelAshley M. VaughanD. Noah SatherSean C. MurphyStefan H. I. Kappe. (2017) Complete attenuation of genetically engineered Plasmodium falciparum sporozoites in human subjects . Science Translational Medicine 9:371.
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Katya Galactionova, Fabrizio Tediosi, Flavia Camponovo, Thomas A. Smith, Peter W. Gething & Melissa A. Penny. (2017) Country specific predictions of the cost-effectiveness of malaria vaccine RTS,S/AS01 in endemic Africa. Vaccine 35:1, pages 53-60.
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