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Original Research

A randomized, blinded study to evaluate the efficacy and safety of umeclidinium 62.5 μg compared with tiotropium 18 μg in patients with COPD

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Pages 719-730 | Published online: 07 Apr 2016

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Pik-Qi Chin, Chau-Chyun Sheu, Jong-Rung Tsai, Hsu-Liang Chang, Li-Yao Lee & Chung-Yu Chen. (2022) Establishing Quality of Life in Southern Taiwan COPD Patients Using Long-Acting Bronchodilator. Patient Preference and Adherence 16, pages 875-886.
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Gema Requena, Daniel Dedman, Jennifer K Quint, Rebecca E Ghosh, Rachael Williams & Jeanne M Pimenta. (2021) The Utilization and Safety of Umeclidinium and Umeclidinium/Vilanterol in UK Primary Care: A Retrospective Cohort Study. International Journal of Chronic Obstructive Pulmonary Disease 16, pages 629-642.
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Jose Luis López-Campos, Laura Carrasco Hernández, Borja Ruiz-Duque, Rocio Reinoso-Arija & Candelaria Caballero-Eraso. (2021) Step-Up and Step-Down Treatment Approaches for COPD: A Holistic View of Progressive Therapies. International Journal of Chronic Obstructive Pulmonary Disease 16, pages 2065-2076.
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Nanshan Zhong, Jinping Zheng, Sang Haak Lee, David A Lipson, Xin Du & Shunquan Wu. (2020) Efficacy and Safety of Once-Daily Inhaled Umeclidinium in Asian Patients with COPD: Results from a Randomized, Placebo-Controlled Study. International Journal of Chronic Obstructive Pulmonary Disease 15, pages 809-819.
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Timothy E Albertson, Willis S Bowman, Richart W Harper, Regina M Godbout & Susan Murin. (2019) Evidence-based review of data on the combination inhaler umeclidinium/vilanterol in patients with COPD. International Journal of Chronic Obstructive Pulmonary Disease 14, pages 1251-1265.
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Jill Ohar, Robert Tosiello, Thomas Goodin & Shahin Sanjar. (2019) Efficacy and safety of a novel, nebulized glycopyrrolate for the treatment of COPD: effect of baseline disease severity and age; pooled analysis of GOLDEN 3 and GOLDEN 4. International Journal of Chronic Obstructive Pulmonary Disease 14, pages 27-37.
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Giulia Parri, Dario Nieri, Maria Adelaide Roggi, Barbara Vagaggini, Alessandro Celi & Pierluigi Paggiaro. (2018) Fluticasone furoate, umeclidinium bromide, and vilanterol as a combination therapy for chronic obstructive pulmonary disease. Expert Review of Respiratory Medicine 12:12, pages 997-1005.
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Edward Kerwin & Gary T. Ferguson. (2018) An overview of glycopyrrolate/eFlow® CS in COPD. Expert Review of Respiratory Medicine 12:6, pages 447-459.
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Mohamed Ismail Abdul Aziz, Ling Eng Tan, David Bin-Chia Wu, Fiona Pearce, Gerald Seng Wee Chua, Liang Lin, Ping-Tee Tan & Kwong Ng. (2018) Comparative efficacy of inhaled medications (ICS/LABA, LAMA, LAMA/LABA and SAMA) for COPD: a systematic review and network meta-analysis. International Journal of Chronic Obstructive Pulmonary Disease 13, pages 3203-3231.
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Chitra Lal & Charlie Strange. (2017) Spotlight on fluticasone furoate/umeclidinium/vilanterol in COPD: design, development, and potential place in therapy. International Journal of Chronic Obstructive Pulmonary Disease 12, pages 135-140.
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Mark A. Mastrodicasa, Christopher A. Droege, Aaron M. Mulhall, Neil E. Ernst, Ralph J. Panos & Muhammad A. Zafar. (2017) Long acting muscarinic antagonists for the treatment of chronic obstructive pulmonary disease: a review of current and developing drugs. Expert Opinion on Investigational Drugs 26:2, pages 161-174.
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Carolina Llanos-Paez, Claire Ambery, Shuying Yang, Misba Beerahee, Elodie L. Plan & Mats O. Karlsson. (2023) Joint longitudinal model-based meta-analysis of FEV1 and exacerbation rate in randomized COPD trials. Journal of Pharmacokinetics and Pharmacodynamics.
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Zhiguo Wang & Baofeng YangZhiguo Wang & Baofeng Yang. 2022. Polypharmacology. Polypharmacology 271 299 .
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S. N. Avdeev, Z. R. Aisanov & A. V. Emelyanov. (2020) First triple therapy in one inhaler for COPD patients: treatment approach (scientific data overview). PULMONOLOGIYA 30:6, pages 813-821.
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Dhvani Shah, Maurice Driessen, Nancy Risebrough, Timothy Baker, Ian Naya, Andrew Briggs & Afisi S. Ismaila. (2018) Cost-effectiveness of umeclidinium compared with tiotropium and glycopyrronium as monotherapy for chronic obstructive pulmonary disease: a UK perspective. Cost Effectiveness and Resource Allocation 16:1.
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M. T. Driessen, J. Whalen, B. Seewoodharry Buguth, L. A. Vallejo-Aparicio, I. P. Naya, Y. Asukai, B. Alcázar-Navarrete, M. Miravitlles, F. García-Río & N. A. Risebrough. (2018) Cost-effectiveness analysis of umeclidinium bromide/vilanterol 62.5/25 mcg versus tiotropium/olodaterol 5/5 mcg in symptomatic patients with chronic obstructive pulmonary disease: a Spanish National Healthcare System perspective. Respiratory Research 19:1.
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Maurice Driessen, Dhvani Shah, Nancy Risebrough, Timothy Baker, Ian Naya, Andrew Briggs & Afisi S. Ismaila. (2018) Cost-effectiveness of umeclidinium as add-on to ICS/LABA therapy in COPD: A UK perspective. Respiratory Medicine 145, pages 130-137.
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Bernardino Alcázar Navarrete, Isabelle Boucot, Ian Naya, Lee Tombs, David A. Lipson, Chris Compton, Ana R. Sousa & Gregory Feldman. (2018) Umeclidinium/Vilanterol Versus Tiotropium/Olodaterol in Maintenance-Naïve Patients with Moderate Symptomatic Chronic Obstructive Pulmonary Disease: A Post Hoc Analysis. Pulmonary Therapy 4:2, pages 171-183.
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Ian P. Naya, Lee Tombs, David A. Lipson & Chris Compton. (2018) Preventing Clinically Important Deterioration of COPD with Addition of Umeclidinium to Inhaled Corticosteroid/Long-Acting β2-Agonist Therapy: An Integrated Post Hoc Analysis. Advances in Therapy 35:10, pages 1626-1638.
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Aya Wail Abukwaik, Rupal Mansukhani & Mary Barna Bridgeman. (2017) Long-Acting Bronchodilator Use in the Management of Stable COPD. Annals of Pharmacotherapy 52:6, pages 562-570.
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Emmanuel Naline, Stanislas Grassin Delyle, Hélène Salvator, Marion Brollo, Christophe Faisy, Tatiana Victoni, Charlotte Abrial & Philippe Devillier. (2018) Comparison of the in vitro pharmacological profiles of long-acting muscarinic antagonists in human bronchus. Pulmonary Pharmacology & Therapeutics 49, pages 46-53.
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Katya Y. J. Sion, Eline L. Huisman, Yogesh S. Punekar, Ian Naya & Afisi S. Ismaila. (2017) A Network Meta-Analysis of Long-Acting Muscarinic Antagonist (LAMA) and Long-Acting β2-Agonist (LABA) Combinations in COPD. Pulmonary Therapy 3:2, pages 297-316.
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Edward Kerwin, Gary T. Ferguson, Shahin Sanjar, Thomas Goodin, Anthony Yadao, Robert Fogel, Samopriyo Maitra, Biswajit Sen, Tim Ayers & Donald Banerji. (2017) Dual Bronchodilation with Indacaterol Maleate/Glycopyrronium Bromide Compared with Umeclidinium Bromide/Vilanterol in Patients with Moderate-to-Severe COPD: Results from Two Randomized, Controlled, Cross-over Studies. Lung 195:6, pages 739-747.
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David M. Halpin, Alan G. Kaplan & Richard K. Russell. (2017) Why choose tiotropium for my patient? A comprehensive review of actions and outcomes versus other bronchodilators. Respiratory Medicine 128, pages 28-41.
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Han Ni, Aung Htet & Soe Moe. (2017) Umeclidinium bromide versus placebo for people with chronic obstructive pulmonary disease (COPD). Cochrane Database of Systematic Reviews 2017:6.
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Kesavan Suresh Babu & Jaymin Bhagwanji Morjaria. (2017) Umeclidinium in chronic obstructive pulmonary disease: latest evidence and place in therapy. Therapeutic Advances in Chronic Disease 8:4-5, pages 81-91.
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Swati Gulati & J. Michael Wells. (2017) Bringing Stability to the Chronic Obstructive Pulmonary Disease Patient: Clinical and Pharmacological Considerations for Frequent Exacerbators. Drugs 77:6, pages 651-670.
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Joy Creaser-Thomas, Vignesh Rajasundaram & Gwyneth A Davies. 2017. A Worldwide Yearly Survey of New Data in Adverse Drug Reactions. A Worldwide Yearly Survey of New Data in Adverse Drug Reactions 161 171 .
Kai M. Beeh. (2016) The Role of Bronchodilators in Preventing Exacerbations of Chronic Obstructive Pulmonary Disease. Tuberculosis and Respiratory Diseases 79:4, pages 241.
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