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International Journal of Chronic Obstructive Pulmonary Disease Volume 16, 2021 - Issue
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Review

Benefit/Risk Profile of Single-Inhaler Triple Therapy in COPD

Jean Bourbeau1 Respiratory Epidemiology and Clinical Research Unit, Department of Medicine, McGill University and Research Institute of the McGill University Health Centre, Montreal, QC, CanadaCorrespondence[email protected]
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Mona Bafadhel2 Nuffield Department of Medicine, University of Oxford, Oxford, Oxfordshire, UKORCID Iconhttps://orcid.org/0000-0002-9993-2478View further author information
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Neil C Barnes3 Respiratory Therapy Area, GlaxoSmithKline, Brentford, Middlesex, UK;4 William Harvey Institute, Bart’s and the London School of Medicine and Dentistry, London, UKORCID Iconhttps://orcid.org/0000-0001-7981-5197View further author information
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Chris Compton3 Respiratory Therapy Area, GlaxoSmithKline, Brentford, Middlesex, UKView further author information
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Valentina Di Boscio3 Respiratory Therapy Area, GlaxoSmithKline, Brentford, Middlesex, UKView further author information
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David A Lipson5 Clinical Sciences, GlaxoSmithKline, Collegeville, PA, USA;6 Pulmonary, Allergy and Critical Care Division, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USAORCID Iconhttps://orcid.org/0000-0001-6732-4593View further author information
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Paul W Jones3 Respiratory Therapy Area, GlaxoSmithKline, Brentford, Middlesex, UK;7 Institute of Infection and Immunity, St George’s, University of London, London, UKORCID Iconhttps://orcid.org/0000-0001-6087-9182View further author information
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Neil Martin3 Respiratory Therapy Area, GlaxoSmithKline, Brentford, Middlesex, UK;8 University of Leicester, Leicester, UKView further author information
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Gudrun Weiss3 Respiratory Therapy Area, GlaxoSmithKline, Brentford, Middlesex, UKView further author information
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David M G Halpin9 University of Exeter Medical School, College of Medicine and Health, University of Exeter, Exeter, UKORCID Iconhttps://orcid.org/0000-0003-2009-4406View further author information
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Pages 499-517 | Published online: 01 Mar 2021

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Marc Miravitlles, Sudeep Acharya, Bhumika Aggarwal, Frederico LA Fernandes, Jorge Dreyse, José R Jardim, Siwasak Juthong, Gur Levy & Martin Sivori. (2023) Clinical Concepts for Triple Therapy Use in Patients with COPD: A Delphi Consensus. International Journal of Chronic Obstructive Pulmonary Disease 18, pages 1853-1866.
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Michael Bogart, Guillaume Germain, François Laliberté, Dominique Lejeune & Mei Sheng Duh. (2023) Real-World Treatment Patterns and Switching Following Moderate/Severe Chronic Obstructive Pulmonary Disease Exacerbation in Patients with Commercial or Medicare Insurance in the United States. International Journal of Chronic Obstructive Pulmonary Disease 18, pages 1575-1586.
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Mario Cazzola, Paola Rogliani, Rossella Laitano, Luigino Calzetta & Maria Gabriella Matera. (2022) Beyond Dual Bronchodilation – Triple Therapy, When and Why. International Journal of Chronic Obstructive Pulmonary Disease 17, pages 165-180.
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Mario Cazzola, Josuel Ora, Luigino Calzetta, Paola Rogliani & Maria Gabriella Matera. (2022) Advances in inhaled corticosteroids for the treatment of chronic obstructive pulmonary disease: what is their value today?. Expert Opinion on Pharmacotherapy 23:8, pages 917-927.
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Maria Gabriella Matera, Luigino Calzetta, Rosa Annibale, Francesco Russo & Mario Cazzola. (2021) Classes of drugs that target the cellular components of inflammation under clinical development for COPD. Expert Review of Clinical Pharmacology 14:8, pages 1015-1027.
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Articles from other publishers (5)

A. Roque, L. Taborda-Barata, Á.A. Cruz, G. Viegi & T. Maricoto. (2023) COPD treatment – a conceptual review based on critical endpoints. Pulmonology 29:5, pages 410-420.
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Matthew Mintz, Igor Barjaktarevic, Donald A. Mahler, Barry Make, Neil Skolnik, Barbara Yawn, Bree Zeyzus-Johns & Nicola A. Hanania. (2023) Reducing the Risk of Mortality in Chronic Obstructive Pulmonary Disease With Pharmacotherapy: A Narrative Review. Mayo Clinic Proceedings 98:2, pages 301-315.
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So-Won Park, A Yeong Lee, Je-Oh Lim, Se-Jin Lee, Woong-Il Kim, Yea-Gin Yang, Bohye Kim, Joong-Sun Kim, Sung-Wook Chae, Kun Na, Yun-Soo Seo & In-Sik Shin. (2022) Loranthus tanakae Franch. & Sav. Suppresses Inflammatory Response in Cigarette Smoke Condensate Exposed Bronchial Epithelial Cells and Mice. Antioxidants 11:10, pages 1885.
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Paolo Solidoro, Carlo Albera, Fulvia Ribolla, Michela Bellocchia, Luisa Brussino & Filippo Patrucco. (2022) Triple Therapy in COPD: Can We Welcome the Reduction in Cardiovascular Risk and Mortality?. Frontiers in Medicine 9.
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Nightingale Syabbalo. (2021) The role of airway remodeling in the pathogenesis and treatment of chronic obstructive pulmonary disease. Journal of Lung, Pulmonary & Respiratory Research 8:3, pages 96-102.
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