505
Views
93
CrossRef citations to date
0
Altmetric
Review

Efficacy and safety of iron-chelation therapy with deferoxamine, deferiprone, and deferasirox for the treatment of iron-loaded patients with non-transfusion-dependent thalassemia syndromes

&
Pages 465-481 | Published online: 29 Jan 2016

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (6)

Rana Adnan Ahmed, Aso Faeq Salih, Shirwan Hamasalih Omer, Heshu Sulaiman Rahman & Luqman Khalid Rasool. (2022) Early Detection of Iron Overload Cardiomyopathy in Transfusion Dependent Thalassemia Patients in Sulaimaniyah City, Iraq. Therapeutics and Clinical Risk Management 18, pages 259-271.
Read now
Raffaele Nuzzi, Giada Geronazzo, Federico Tridico, Alessia Nuzzi, Paolo Caselgrandi & Antonio Giulio Piga. (2021) Long-Term Effects of Iron Chelating Agents on Ocular Function in Patients with Thalassemia Major. Clinical Ophthalmology 15, pages 2099-2109.
Read now
Jiansong Qi, Yanhong Xing, Yucheng Liu, Meng-Meng Wang, Xiangqing Wei, Zhongheng Sui, Lin Ding, Yang Zhang, Chen Lu, Yuan-Hui Fei, Nan Liu, Rong Chen, Mengmei Wu, Lijuan Wang, Zhenyu Zhong, Ting Wang, Yifan Liu, Yuqing Wang, Jiamei Liu, Haoxing Xu, Feng Guo & Wuyang Wang. (2021) MCOLN1/TRPML1 finely controls oncogenic autophagy in cancer by mediating zinc influx. Autophagy 17:12, pages 4401-4422.
Read now
Mongkhon Sompornrattanaphan, Thanachit Krikeerati, Chamard Wongsa, Torpong Thongngarm & Kittika Yampayon. (2020) Successful Deferasirox Rechallenge and Treating Through Reaction in a Patient with Challenge-Proven Mild Immediate Reaction: A Case Report. Journal of Asthma and Allergy 13, pages 557-561.
Read now
George J. Kontoghiorghes. (2020) How to manage iron toxicity in post-allogeneic hematopoietic stem cell transplantation?. Expert Review of Hematology 13:4, pages 299-302.
Read now
Ali T Taher, John B Porter, Antonis Kattamis, Vip Viprakasit & M Domenica Cappellini. (2016) Efficacy and safety of iron-chelation therapy with deferoxamine, deferiprone, and deferasirox for the treatment of iron-loaded patients with nontransfusion-dependent thalassemia syndromes. Drug Design, Development and Therapy 10, pages 4073-4078.
Read now

Articles from other publishers (87)

Gourav Singh, Prashant Kesharwani, Gireesh Kumar Singh, Saroj Kumar, Anjaneyulu Putta & Gyan Modi. (2024) Ferroptosis and its modulators: A raising target for cancer and Alzheimer’s disease. Bioorganic & Medicinal Chemistry 98, pages 117564.
Crossref
Niloofar Deravi, Narges Norouzkhani, Kimia Keylani, Seyedeh Mona Haghi & Seyyed Kiarash Sadat Rafiei. 2024. Encyclopedia of Toxicology. Encyclopedia of Toxicology 519 531 .
Ryan Njeim, Bilal Naouss, Rayan Bou-Fakhredin, Antoine Haddad & Ali Taher. (2023) Unmet needs in β-thalassemia and the evolving treatment landscape. Transfusion Clinique et Biologique.
Crossref
George J. Kontoghiorghes. (2023) Drug Selection and Posology, Optimal Therapies and Risk/Benefit Assessment in Medicine: The Paradigm of Iron-Chelating Drugs. International Journal of Molecular Sciences 24:23, pages 16749.
Crossref
Tanya Ramadoss, Derek S Weimer & Harvey N Mayrovitz. (2023) Topical Iron Chelator Therapy: Current Status and Future Prospects. Cureus.
Crossref
Evgenia Olshvang, Sarah Fritsch, Oliver C. Scholtyssek, Isabelle J. Schalk & Nils Metzler‐Nolte. (2023) Vectorization via Siderophores Increases Antibacterial Activity of K(RW) 3 Peptides against Pseudomonas aeruginosa . Chemistry – A European Journal 29:50.
Crossref
George J. Kontoghiorghes. (2023) Iron Load Toxicity in Medicine: From Molecular and Cellular Aspects to Clinical Implications. International Journal of Molecular Sciences 24:16, pages 12928.
Crossref
Vip Viprakasit, Mona M. Hamdy, Hoda M. A. Hassab, Laila M. Sherief, Muneer Al-Bagshi, Mohammed Khattab, Suporn Chuncharunee, Phu Chi Dung, Alphan Küpesiz, Ankita Shekhawat, Yamini Sonawane, Laura Torres Perez, Cassandra Slader & Ali T. Taher. (2023) Patient preference for deferasirox film-coated versus dispersible tablet formulation: a sequential-design phase 2 study in patients with thalassemia. Annals of Hematology 102:8, pages 2039-2049.
Crossref
George J. Kontoghiorghes. (2023) The Vital Role Played by Deferiprone in the Transition of Thalassaemia from a Fatal to a Chronic Disease and Challenges in Its Repurposing for Use in Non-Iron-Loaded Diseases. Pharmaceuticals 16:7, pages 1016.
Crossref
Francisco Salazar-Cornejo, Abraham Gajardo, Marcelo J. Kogan & Ramón Rodrigo. 2023. Blood Oxidant Ties: The Evolving Concepts in Myocardial Injury and Cardiovascular Disease. Blood Oxidant Ties: The Evolving Concepts in Myocardial Injury and Cardiovascular Disease 128 147 .
Yan Lin, Xiaoyu Zhang, Haoran Li & Dali Mu. (2023) Deferoxamine Mesylate Improves the Survival Rate of Transplanted Fat by Promoting Angiogenesis. Aesthetic Surgery Journal 43:7, pages 789-798.
Crossref
Ling Deng, Man-Qiu Mo, Jinling Zhong, Zhengming Li, Guoqiao Li & Yuzhen Liang. (2023) Iron overload induces islet β cell ferroptosis by activating ASK1/P-P38/CHOP signaling pathway. PeerJ 11, pages e15206.
Crossref
Itrat Fatima, Wafia Affan, Hira Hameed, Wajeeha Amber, Sumbal Saeed & Imran Mahmood Khan. (2023) Positive Findings of Blood Cultures in Febrile Children Presenting with Thalassemia Major in a Tertiary Care Hospital. Journal of Rawalpindi Medical College 27:1.
Crossref
Ryota Suzuki & Nobuhiko Iki. (2023) Kinetic aspects of iron(III)-chelation therapy with deferasirox (DFX) revealed by the solvolytic dissociation rate of the Fe(III)–DFX complex estimated with capillary electrophoretic reactor. Journal of Inorganic Biochemistry 241, pages 112131.
Crossref
Blue-leaf A. Cordes, Andrea Bilger, Richard J. Kraus, Ella T. Ward-Shaw, Madeline R. Labott, Shinhyo Lee, Paul F. Lambert & Janet E. Mertz. (2023) Drugs That Mimic Hypoxia Selectively Target EBV-Positive Gastric Cancer Cells. Cancers 15:6, pages 1846.
Crossref
George J. Kontoghiorghes. (2023) Deferiprone and Iron–Maltol: Forty Years since Their Discovery and Insights into Their Drug Design, Development, Clinical Use and Future Prospects. International Journal of Molecular Sciences 24:5, pages 4970.
Crossref
Shuolin Cui, Zhi Liu, Tamas Nagy, Elizabeth Oladoyin Agboluaje & May P. Xiong. (2023) Oral Non-absorbable Polymer–Deferoxamine Conjugates for Reducing Dietary Iron Absorption. Molecular Pharmaceutics 20:2, pages 1285-1295.
Crossref
Gregory Jones, Lingxue Zeng & Jonghan Kim. (2022) Mechanism-Based Pharmacokinetic Modeling of Absorption and Disposition of a Deferoxamine-Based Nanochelator in Rats. Molecular Pharmaceutics 20:1, pages 481-490.
Crossref
Sulaiman Yusuf, Heru Noviat Herdata, Eka Destianti Edward & Khairunnisa Khairunnisa. (2023) Comparison of oral iron chelators in the management of transfusion-dependent β-thalassemia major based on serum ferritin and liver enzymes. F1000Research 12, pages 154.
Crossref
Sulaiman Yusuf, Heru Noviat Herdata, Eka Destianti Edward & Khairunnisa Khairunnisa. (2023) Comparison of oral iron chelators in the management of transfusion-dependent β-thalassemia major based on serum ferritin and liver enzymes. F1000Research 12, pages 154.
Crossref
Naying Zheng, Xiaolian Sun, Yiyue Shi, Luheng Chen, Luanjin Wang, Haoxing Cai, Changshun Han, Tingting Liao, Chunyan Yang, Zhenghong Zuo & Chengyong He. (2023) The valence state of iron-based nanomaterials determines the ferroptosis potential in a zebrafish model. Science of The Total Environment 855, pages 158715.
Crossref
Luca Valenti, Serena Pelusi & Luisa Ronzoni. 2023. Comprehensive Guide to Hepatitis Advances. Comprehensive Guide to Hepatitis Advances 443 458 .
Gourav Singh, Nishant Kumar Rana, Indubhusan Mishra & Gyan Prakash Modi. 2023. Natural Product-based Synthetic Drug Molecules in Alzheimer's Disease. Natural Product-based Synthetic Drug Molecules in Alzheimer's Disease 375 400 .
Kornvipa Settakorn, Sarawut Kongkarnka, Anchan Chompupoung, Saovaros Svasti, Suthat Fucharoen, John B. Porter, Somdet Srichairatanakool & Pimpisid Koonyosying. (2022) Effects of green tea extract treatment on erythropoiesis and iron parameters in iron-overloaded β-thalassemic mice. Frontiers in Physiology 13.
Crossref
U. U. Rakhmanova. (2022) Comparative characteristics of humoral immunity indicators and their relationship with chelation therapy in thalassemia. Meditsinskiy sovet = Medical Council:19, pages 162-166.
Crossref
Athina G. Mantelou, Alexandra Barbouti, Anna Goussia, Argyro Zacharioudaki, Alexandra Papoudou-Bai, Chara Vlachou, Stelios Kokkoris, Apostolos Papalois, Dimitrios Galaris & Georgios K. Glantzounis. (2022) Combined administration of membrane-permeable and impermeable iron-chelating drugs attenuates ischemia/reperfusion-induced hepatic injury. Free Radical Biology and Medicine 193, pages 227-237.
Crossref
Hwazen Shash. (2022) Non-Transfusion-Dependent Thalassemia: A Panoramic Review. Medicina 58:10, pages 1496.
Crossref
Chitrakshi A Choubisa, Moli Jain, Vishnu Vardhan, Yukta J Budhwani & Akanksha R Hege. (2022) Concomitant Pre- and Post-splenectomy Physiotherapy Rehabilitation in a 17-Year-Old Patient With Beta Thalassemia Major: A Case Report. Cureus.
Crossref
Gregory Jones, Lingxue Zeng, Wesley R Stiles, Seung Hun Park, Homan Kang, Hak Soo Choi & Jonghan Kim. (2022) Pharmacokinetics and tissue distribution of deferoxamine-based nanochelator in rats. Nanomedicine 17:22, pages 1649-1662.
Crossref
Francesca Rossi, Chiara Tortora, Martina Di Martino, Alessandra Di Paola, Daniela Di Pinto, Maria Maddalena Marrapodi, Maura Argenziano & Elvira Pota. (2022) Alteration of osteoclast activity in childhood cancer survivors: Role of iron and of CB2/TRPV1 receptors. PLOS ONE 17:7, pages e0271730.
Crossref
Sufia Islam, Nazia Hoque, Nishat Nasrin, Mehnaz Hossain, Farhana Rizwan, Kushal Biswas, Muhammad Asaduzzaman, Sabera Rahman, David W. Hoskin, Saki Sultana & Christian Lehmann. (2022) Iron Overload and Breast Cancer: Iron Chelation as a Potential Therapeutic Approach. Life 12:7, pages 963.
Crossref
Dmitry Frank, Alexander Zlotnik, Matthew Boyko & Benjamin Fredrick Gruenbaum. (2022) The Development of Novel Drug Treatments for Stroke Patients: A Review. International Journal of Molecular Sciences 23:10, pages 5796.
Crossref
Sarina Entezari, Seyedeh Mona Haghi, Narges Norouzkhani, Barsa Sahebnazar, Fatemeh Vosoughian, Diba Akbarzadeh, Muhammad Islampanah, Navid Naghsh, Mohammad Abbasalizadeh & Niloofar Deravi. (2022) Iron Chelators in Treatment of Iron Overload. Journal of Toxicology 2022, pages 1-18.
Crossref
Bin Yan, Daoli Xie, Yuancheng Wu, Shuli Wang, Xiaolin Zhang, Tong Zhao, Luying Liu, Peng Ma, Guqiang Li, Ying Yang, Yucheng Zhao, Tihua Zheng, Ruishuang Geng, Bo Li & Qingyin Zheng. (2022) Ferroptosis is involved in PGPS-induced otitis media in C57BL/6 mice. Cell Death Discovery 8:1.
Crossref
George J. Kontoghiorghes. (2022) Questioning Established Theories and Treatment Methods Related to Iron and Other Metal Metabolic Changes, Affecting All Major Diseases and Billions of Patients. International Journal of Molecular Sciences 23:3, pages 1364.
Crossref
Viktor A. Timoshnikov, Olga Yu. Selyutina, Nikolay E. Polyakov, Victoria Didichenko & George J. Kontoghiorghes. (2022) Mechanistic Insights of Chelator Complexes with Essential Transition Metals: Antioxidant/Pro-Oxidant Activity and Applications in Medicine. International Journal of Molecular Sciences 23:3, pages 1247.
Crossref
Noppawan Phumala Morales, Supot Rodrat, Pannaree Piromkraipak, Paveena Yamanont, Kittiphong Paiboonsukwong & Suthat Fucharoen. (2022) Iron chelation therapy with deferiprone improves oxidative status and red blood cell quality and reduces redox-active iron in β-thalassemia/hemoglobin E patients. Biomedicine & Pharmacotherapy 145, pages 112381.
Crossref
Lars Gerhardsson. 2022. Handbook on the Toxicology of Metals. Handbook on the Toxicology of Metals 663 684 .
Ming-Yue Li, Xiao-Hong Dai, Xue-Ping Yu, Wei Zou, Wei Teng, Peng Liu, Xin-Yang Yu, Qi An & Xin Wen. (2021) Scalp Acupuncture Protects Against Neuronal Ferroptosis by Activating The p62-Keap1-Nrf2 Pathway in Rat Models of Intracranial Haemorrhage. Journal of Molecular Neuroscience 72:1, pages 82-96.
Crossref
Omer Sefvan Janjua, Muhammad Saad Shaikh, Muhammad Amber Fareed, Sana Mehmood Qureshi, Muhammad Ikram Khan, Danya Hashem & Muhammad Sohail Zafar. (2021) Dental and Oral Manifestations of COVID-19 Related Mucormycosis: Diagnoses, Management Strategies and Outcomes. Journal of Fungi 8:1, pages 44.
Crossref
Rodrigo Díaz, José Troncoso, Eva Jakob & Stanko Skugor. (2021) “Limiting access to iron decreases infection of Atlantic salmon SHK-1 cells with bacterium Piscirickettsia salmonis”. BMC Veterinary Research 17:1.
Crossref
Melanie L Bailey, David Tieu, Andrea Habsid, Amy Hin Yan Tong, Katherine Chan, Jason Moffat & Philip Hieter. (2021) Paralogous synthetic lethality underlies genetic dependencies of the cancer-mutated gene STAG2 . Life Science Alliance 4:11, pages e202101083.
Crossref
Mireille M.J.P.E. Sthijns, Clemens A. van Blitterswijk & Vanessa L.S. LaPointe. (2021) Synthetic Materials that Affect the Extracellular Matrix via Cellular Metabolism and Responses to a Metabolic State. Frontiers in Bioengineering and Biotechnology 9.
Crossref
Rana M. Adel, Rania A. Lotfy, Atef S. Darwish & Amany S. Amer. (2021) Destructive effect of iron overload in brain tissue of albino rats: Ameliorative role of silver immobilized organo-modified casein nanocomposite as co-treating agent with Deferasirox. Journal of Trace Elements in Medicine and Biology 67, pages 126794.
Crossref
Viktor A. Timoshnikov, Lilia A. Kichigina, Olga Yu. Selyutina, Nikolay E. Polyakov & George J. Kontoghiorghes. (2021) Antioxidant Activity of Deferasirox and Its Metal Complexes in Model Systems of Oxidative Damage: Comparison with Deferiprone. Molecules 26:16, pages 5064.
Crossref
George J. Kontoghiorghes. (2021) Differences between the European Union and United States of America in Drug Regulatory Affairs Affect Global Patient Safety Standards and Public Health Awareness: The Case of Deferasirox and Other Iron Chelating Drugs. Medicines 8:7, pages 36.
Crossref
George Kontoghiorghes, Annita Kolnagou, Theodora Demetriou, Marina Neocleous & Christina Kontoghiorghe. (2021) New Era in the Treatment of Iron Deficiency Anaemia Using Trimaltol Iron and Other Lipophilic Iron Chelator Complexes: Historical Perspectives of Discovery and Future Applications. International Journal of Molecular Sciences 22:11, pages 5546.
Crossref
Zhenyu Zhai, Pengtao Zou, Fuxiang Liu, Zirong Xia & Juxiang Li. (2021) Ferroptosis Is a Potential Novel Diagnostic and Therapeutic Target for Patients With Cardiomyopathy. Frontiers in Cell and Developmental Biology 9.
Crossref
Chantel Cacciotti & Uma Athale. (2021) Transfusion-related Iron Overload in Children With Leukemia. Journal of Pediatric Hematology/Oncology 43:1, pages 18-23.
Crossref
Susan Schubach Slater & Lisa K. Hansen. 2021. Blood and Marrow Transplant Handbook. Blood and Marrow Transplant Handbook 807 828 .
Sharanya Manoharan, Oviya Iyappan Ramalakshmi & Sathishkumar Ramasamy. 2021. Fungal Siderophores. Fungal Siderophores 141 156 .
Jing Wu, Jian-Jun Yang, Yan Cao, Huihui Li, Hongting Zhao, Shuofei Yang & Kuanyu Li. (2020) Iron overload contributes to general anaesthesia-induced neurotoxicity and cognitive deficits. Journal of Neuroinflammation 17:1.
Crossref
Sorasak Makmettakul, Adisak Tantiworawit, Arintaya Phrommintikul, Pokpong Piriyakhuntorn, Thanawat Rattanathammethee, Sasinee Hantrakool, Chatree Chai-Adisaksopha, Ekarat Rattarittamrong, Lalita Norasetthada, Kanda Fanhchaksai, Pimlak Charoenkwan & Suree Lekawanvijit. (2020) Cardiorenal syndrome in thalassemia patients. BMC Nephrology 21:1.
Crossref
Damini Tewari, Katie Lloyd‐Jones, Robert C. Hider & Helen Collins. (2020) HPO iron chelator, CP655, causes the G1/S phase cell cycle block via p21 upregulation. Immunity, Inflammation and Disease 8:4, pages 568-583.
Crossref
Gülüzar Özbolat & Arash Alizadeh Yegani. (2020) Synthesis, characterization, biological activity and electrochemistry studies of iron(III) complex with curcumin‐oxime ligand. Clinical and Experimental Pharmacology and Physiology 47:11, pages 1834-1842.
Crossref
George T. Mukosera, Taiming Liu, Meshach Manaen, Lingchao Zhu, Gordon Power, Hobe Schroeder & Arlin B. Blood. (2020) Deferoxamine produces nitric oxide under ferricyanide oxidation, blood incubation, and UV-irradiation. Free Radical Biology and Medicine 160, pages 458-470.
Crossref
N. A. Batmanova, T. T. Valiev, K. I. Kirgizov & S. R. Varfolomeeva. (2020) Diagnosis and treatment of post-transfusion iron overload in pediatric hematology: literature review. Russian Journal of Pediatric Hematology and Oncology 7:3, pages 70-77.
Crossref
Dominik Arbon, Kateřina Ženíšková, Jan Mach, Maria Grechnikova, Ronald Malych, Pavel Talacko & Robert Sutak. (2020) Adaptive iron utilization compensates for the lack of an inducible uptake system in Naegleria fowleri and represents a potential target for therapeutic intervention. PLOS Neglected Tropical Diseases 14:6, pages e0007759.
Crossref
George Kontoghiorghes & Christina Kontoghiorghe. (2020) Iron and Chelation in Biochemistry and Medicine: New Approaches to Controlling Iron Metabolism and Treating Related Diseases. Cells 9:6, pages 1456.
Crossref
Gregory Jones, Sumanta Kumar Goswami, Homan Kang, Hak Soo Choi & Jonghan Kim. (2020) Combating iron overload: a case for deferoxamine-based nanochelators. Nanomedicine 15:13, pages 1341-1356.
Crossref
George J. Kontoghiorghes. (2020) Advances on Chelation and Chelator Metal Complexes in Medicine. International Journal of Molecular Sciences 21:7, pages 2499.
Crossref
Hayder Al-Momen, Hussein Khudhair Hussein, Zaid Al-Attar & Mohammed Jalal Hussein. (2020) Green tea influence on iron overload in thalassemia intermedia patients: a randomized controlled trial. F1000Research 9, pages 1136.
Crossref
Johannes Ermert, Martina Benešová, Verena Hugenberg, Viplav Gupta, Ingo Spahn, Hans-Jürgen Pietzsch, Christos Liolios & Klaus Kopka. 2020. Clinical Nuclear Medicine. Clinical Nuclear Medicine 49 191 .
Frank Richard, Jan Jaap van Lier, Bernard Roubert, Teba Haboubi, Udo‐Michael Göhring & Franz Dürrenberger. (2019) Oral ferroportin inhibitor VIT‐2763: First‐in‐human, phase 1 study in healthy volunteers. American Journal of Hematology 95:1, pages 68-77.
Crossref
Lingjuan Wang, Xiaoqing Li, Yanxi Mu, Chang Lu, Shiqian Tang, Kun Lu, Xiaoming Qiu, Aili Wei, Yongjiu Cheng & Wei Wei. (2019) The iron chelator desferrioxamine synergizes with chemotherapy for cancer treatment. Journal of Trace Elements in Medicine and Biology 56, pages 131-138.
Crossref
Jacob Kosyakovsky, Bruce A. Witthuhn, Aleta L. Svitak, William H. FreyIIII, Leah R. Hanson & Jared M. Fine. (2019) Quantifying Intranasally Administered Deferoxamine in Rat Brain Tissue with Mass Spectrometry. ACS Chemical Neuroscience 10:11, pages 4571-4578.
Crossref
Eman M. Hamed, Mohamed Hussein Meabed, Usama Farghaly Aly & Raghda R.S. Hussein. (2019) Recent Progress in Gene Therapy and Other Targeted Therapeutic Approaches for Beta Thalassemia. Current Drug Targets 20:16, pages 1603-1623.
Crossref
Piu Saha, Beng San Yeoh, Xia Xiao, Rachel M. Golonka, Sivarajan Kumarasamy & Matam Vijay-Kumar. (2019) Enterobactin, an iron chelating bacterial siderophore, arrests cancer cell proliferation. Biochemical Pharmacology 168, pages 71-81.
Crossref
Tadeu Gonçalves de Lima, Fernanda Luna Neri Benevides, Flávio Lima Esmeraldo Filho, Igor Silva Farias, Diovana Ximenes Cavalcante Dourado, Eveline Gadelha Pereira Fontenele, Maria Elisabete Amaral de Moraes & Ana Rosa Pinto Quidute. (2019) Treatment of iron overload syndrome: a general review. Revista da Associação Médica Brasileira 65:9, pages 1216-1222.
Crossref
Marianna Tosato & Valerio Di Marco. (2019) Metal Chelation Therapy and Parkinson’s Disease: A Critical Review on the Thermodynamics of Complex Formation between Relevant Metal Ions and Promising or Established Drugs. Biomolecules 9:7, pages 269.
Crossref
Azam Ghazanfari, Ebrahim Jafarzadehpour, Samira Heydarian, Kiumars Nowroozpoor Dailami & Hosein Karami. (2019) Comparison of contrast sensitivity in β-thalassemia patients treated by deferoxamine or deferasirox. Journal of Optometry 12:3, pages 168-173.
Crossref
Türker Acar, Egemen Kaya, Mustafa Deniz Yoruk, Neslihan Duzenli, Recep Selim Senturk, Cenk Can, Lokman Ozturk, Canberk Tomruk, Yigit Uyanikgil & Frank J. Rybicki. (2019) Changes in tissue gadolinium biodistribution measured in an animal model exposed to four chelating agents. Japanese Journal of Radiology 37:6, pages 458-465.
Crossref
Xiaomei Wang, Suqiang Wu, Jingwen Guan, Lanhua Chen, Cen Shi, Jianmei Wan, Yong Liu, Juan Diwu, Jianqiang Wang & Shuao Wang. (2019) 3-Hydroxy-2-Pyrrolidinone as a Potential Bidentate Ligand for in Vivo Chelation of Uranyl with Low Cytotoxicity and Moderate Decorporation Efficacy: A Solution Thermodynamics, Structural Chemistry, and in Vivo Uranyl Removal Survey . Inorganic Chemistry 58:5, pages 3349-3354.
Crossref
Nancy F. Olivieri, Amir Sabouhanian & Brenda L. Gallie. (2019) Single-center retrospective study of the effectiveness and toxicity of the oral iron chelating drugs deferiprone and deferasirox. PLOS ONE 14:2, pages e0211942.
Crossref
Antoine Finianos, Charbel Matar & Ali Taher. (2018) Hepatocellular Carcinoma in β-Thalassemia Patients: Review of the Literature with Molecular Insight into Liver Carcinogenesis. International Journal of Molecular Sciences 19:12, pages 4070.
Crossref
Ahlam Alhusaini, Laila Fadda, Iman Hassan, Hanaa M. Ali, Njood Alsaadan, Nouf Aldowsari, Azizah Aldosari & Bshayer Alharbi. (2018) Liposomal Curcumin Attenuates the Incidence of Oxidative Stress, Inflammation, and DNA Damage Induced by Copper Sulfate in Rat Liver. Dose-Response 16:3, pages 155932581879086.
Crossref
Maria Domenica Cappellini, John B. Porter, Vip Viprakasit & Ali T. Taher. (2018) A paradigm shift on beta-thalassaemia treatment: How will we manage this old disease with new therapies?. Blood Reviews 32:4, pages 300-311.
Crossref
Chingiz Asadov, Zohra Alimirzoeva, Tahira Mammadova, Gunay Aliyeva, Shahla Gafarova & Jeyhun Mammadov. (2018) β-Thalassemia intermedia: a comprehensive overview and novel approaches. International Journal of Hematology 108:1, pages 5-21.
Crossref
Victor L. Correa, Kristine M. Garza & Lawrence E. Murr. (2017) Vascularization in interconnected 3D printed Ti-6Al-4V foams with hydrogel matrix for biomedical bone replacement implants. Science China Materials 61:4, pages 565-578.
Crossref
Ari EstuningtyasKlaus ZwickerTri WahyuniPurnama FajriPustika Amalia WahidiyatSeruni K.U. FreislebenHans-Joachim Freisleben. (2018) Are Mangiferin and Mangiferin-Containing Plant Extracts Helpful for Iron-Loaded Transfusion-Dependent and Non-Transfusion-Dependent Thalassaemia Patients?. Biomedical and Pharmacology Journal 11:1, pages 29-43.
Crossref
Xiaomei Wang, Guoxun Ji, Cen Shi, Juan Diwu, Lanhua Chen, Daxiang Gui, Jianmei Wan, Mark A. Silver, Jianqiang Wang & Shuao Wang. (2018) Structural and thermodynamic stability of uranyl–deferiprone complexes and the removal efficacy of U( vi ) at the cellular level . Dalton Transactions 47:26, pages 8764-8770.
Crossref
Melissa Ellermann & Janelle C. Arthur. (2017) Siderophore-mediated iron acquisition and modulation of host-bacterial interactions. Free Radical Biology and Medicine 105, pages 68-78.
Crossref
Milos Petrik, Chuangyan Zhai, Hubertus Haas & Clemens Decristoforo. (2016) Siderophores for molecular imaging applications. Clinical and Translational Imaging 5:1, pages 15-27.
Crossref
Joshua P. Gray, Natalia Suhali-Amacher & Sidhartha D. Ray. 2017. A Worldwide Yearly Survey of New Data in Adverse Drug Reactions. A Worldwide Yearly Survey of New Data in Adverse Drug Reactions 197 208 .
Colette Kurth, Hirokazu Kage & Markus Nett. (2016) Siderophores as molecular tools in medical and environmental applications. Organic & Biomolecular Chemistry 14:35, pages 8212-8227.
Crossref
Naying Zheng, Xiaolian Sun, Yiyue Shi, Luheng Chen, Luanjin Wang, Haoxing Cai, Changshun Han, Tingting Liao, Chunyan Yang, Zhenghong Zuo & Chengyong He. (2022) The Valence State of Iron-Based Nanomaterials Determines the Ferroptosis Potential in a Zebrafish Model. SSRN Electronic Journal.
Crossref
Gourav Singh, Prashant Kesharwani, Bhupendra Kumar, Indubhusan Mishra, Saroj Kumar & Gyan Modi. (2022) Ferroptosis a Futuristic Roadmap for Cancer and Alzheimer's Disease. SSRN Electronic Journal.
Crossref