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Original Research

Tailoring of PEGylated bilosomes for promoting the transdermal delivery of olmesartan medoxomil: in-vitro characterization, ex-vivo permeation and in-vivo assessment

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Pages 6555-6574 | Published online: 15 Aug 2019

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Read on this site (19)

Reem Abou Assi, Ibrahim M. Abdulbaqi, Siew Mei Tan, Habibah A. Wahab, Yusrida Darwis & Siok-Yee Chan. (2023) Breaking barriers: bilosomes gel potentials to pave the way for transdermal breast cancer treatment with Tamoxifen. Drug Development and Industrial Pharmacy 0:0, pages 1-12.
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Christian Höcht, Miguel A Allo, Ariel Héctor Polizio, Marcela A Morettón, Andrea Carranza, Diego A Chiappetta & Marcelo Roberto Choi. (2022) New and developing pharmacotherapies for hypertension. Expert Review of Cardiovascular Therapy 20:8, pages 647-666.
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Heba F Salem, Mohammed M Nafady, Adel A Ali, Nermeen M Khalil & Amani A Elsisi. (2022) Evaluation of Metformin Hydrochloride Tailoring Bilosomes as an Effective Transdermal Nanocarrier. International Journal of Nanomedicine 17, pages 1185-1201.
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Mohamed El-Nabarawi, Mohamed Nafady, Shahira Elmenshawe, Marwa Elkarmalawy & Mahmoud Teaima. (2021) Liver Targeting of Daclatasvir via Tailoring Sterically Stabilized Bilosomes: Fabrication, Comparative In Vitro/In Vivo Appraisal and Biodistribution Studies. International Journal of Nanomedicine 16, pages 6413-6426.
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Rofida Albash, Menna M Abdellatif, Mariam Hassan & Noha M Badawi. (2021) Tailoring Terpesomes and Leciplex for the Effective Ocular Conveyance of Moxifloxacin Hydrochloride (Comparative Assessment): In-vitro, Ex-vivo, and In-vivo Evaluation. International Journal of Nanomedicine 16, pages 5247-5263.
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Rofida Albash, Abdulaziz Mohsen Al-mahallawi, Mariam Hassan & Ahmed Adel Alaa-Eldin. (2021) Development and Optimization of Terpene-Enriched Vesicles (Terpesomes) for Effective Ocular Delivery of Fenticonazole Nitrate: In vitro Characterization and in vivo Assessment. International Journal of Nanomedicine 16, pages 609-621.
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Ameeduzzafar Zafar, Nabil K. Alruwaili, Syed Sarim Imam, Omar Awad Alsaidan, Mohd Yasir, Mohammed M. Ghoneim, Sultan Alshehri, Md. Khalid Anwer, Alanood S. Almurshedi & Abdullah S. Alanazi. (2021) Development and evaluation of luteolin loaded pegylated bilosome: optimization, in vitro characterization, and cytotoxicity study. Drug Delivery 28:1, pages 2562-2573.
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Tarek M. Ibrahim. (2023) Exploitation of transdermal nanobilosomal gel platforms for ameliorating anti-diabetic activity of empagliflozin following I-optimal design. Journal of Drug Delivery Science and Technology 84, pages 104455.
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Ayman Abo Elmaaty, Ahmed A. Al‐Karmalawy, Mohamed S. Nafie, Marium M. Shamaa, Islam Zaki, Radwan Alnajjar & Mohamed Y. Zakaria. (2023) Experimental design of D-α-tocopherol polyethylene glycol 1000 succinate stabilized bile salt based Nano-vesicles for improved cytotoxicity and bioavailability of colchicine binding site inhibitor Candidates: In Vitro, in silico, and pharmacokinetic studies. International Journal of Pharmaceutics 640, pages 122980.
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Mariam Zewail, Passent M. E. Gaafar, Nancy Abdel Hamid Abou Youssef, Merhan E. Ali, Mai F. Ragab, Miranda F. Kamal, Mohamed H. Noureldin & Haidy Abbas. (2022) Novel Siprulina platensis Bilosomes for Combating UVB Induced Skin Damage. Pharmaceuticals 16:1, pages 36.
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Y. Han, Z.Y. Jin, D.S. Zhang, B.B. Hu, Z.Q. Li, Y.S. Jing & S.G. Sun. (2022) Application of polymers in promoting transdermal absorption. Materials Today Chemistry 26, pages 101204.
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Pengcheng Deng, Felemban Athary Abdulhaleem M, Reham E. Masoud, Wael M. Alamoudi & Mohamed Y. Zakaria. (2022) “Employment of PEGylated ultra-deformable transferosomes for transdermal delivery of tapentadol with boosted bioavailability and analgesic activity in post-surgical pain”. International Journal of Pharmaceutics 628, pages 122274.
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María Javiera Alvarez-Figueroa, Diego A. Alarcón & José Vicente González-Aramúndiz. (2022) Effect of zeta potential of innovative lipid nanocapsules on triamcinolone transdermal delivery. Drug Delivery and Translational Research 12:11, pages 2740-2750.
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Crossref
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Crossref
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Crossref
Indhu A. Chacko, Vivek M. Ghate, Leonna Dsouza & Shaila A. Lewis. (2020) Lipid vesicles: A versatile drug delivery platform for dermal and transdermal applications. Colloids and Surfaces B: Biointerfaces 195, pages 111262.
Crossref
Dina B. Mahmoud, Samar A. Afifi & Nesrine S. El Sayed. (2020) Crown Ether Nanovesicles (Crownsomes) Repositioned Phenytoin for Healing of Corneal Ulcers. Molecular Pharmaceutics 17:10, pages 3952-3965.
Crossref
Viraj Shah, Rahul Mittal, David Shahal, Priyanka Sinha, Erdogan Bulut, Jeenu Mittal & Adrien A. Eshraghi. (2020) Evaluating the Efficacy of Taurodeoxycholic Acid in Providing Otoprotection Using an in vitro Model of Electrode Insertion Trauma. Frontiers in Molecular Neuroscience 13.
Crossref
Marianne J. Naguib, Salwa Salah, Sally A. Abdel Halim & Shaimaa M. Badr-Eldin. (2020) Investigating the potential of utilizing glycerosomes as a novel vesicular platform for enhancing intranasal delivery of lacidipine. International Journal of Pharmaceutics 582, pages 119302.
Crossref