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International Journal of Nanomedicine Volume 16, 2021 - Issue
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Review

Potential of Exosomes as Cell-Free Therapy in Articular Cartilage Regeneration: A Review

Chiew Yong Ng1 Centre for Tissue Engineering and Regenerative Medicine, Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur, 56000, MalaysiaORCID Iconhttps://orcid.org/0000-0002-5365-6471View further author information
ORCID Icon,
Jia Ying Chai1 Centre for Tissue Engineering and Regenerative Medicine, Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur, 56000, MalaysiaView further author information
,
Jhi Biau Foo2 School of Pharmacy, Faculty of Health and Medical Sciences, Taylor’s University, Subang Jaya, 47500, Selangor, Malaysia;3 Centre for Drug Discovery and Molecular Pharmacology (CDDMP), Faculty of Health and Medical Sciences, Taylor's University, Subang Jaya, Selangor, 47500, MalaysiaORCID Iconhttps://orcid.org/0000-0002-5880-2220View further author information
ORCID Icon,
Nor Hamdan Mohamad Yahaya4 Department of Orthopaedics and Traumatology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur, 56000, MalaysiaView further author information
,
Ying Yang5 School of Pharmacy and Bioengineering, Keele University, Stoke-on-Trent, ST4 7QB, UKORCID Iconhttps://orcid.org/0000-0002-1362-6040View further author information
ORCID Icon,
Min Hwei Ng1 Centre for Tissue Engineering and Regenerative Medicine, Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur, 56000, MalaysiaORCID Iconhttps://orcid.org/0000-0002-5791-639XView further author information
ORCID Icon &
Jia Xian Law1 Centre for Tissue Engineering and Regenerative Medicine, Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur, 56000, MalaysiaCorrespondence[email protected] [email protected]
ORCID Iconhttps://orcid.org/0000-0001-9045-5145View further author information
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Pages 6749-6781 | Published online: 01 Oct 2021

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Yuping Chen, Bingtian Dong, Lichun Huang, Jingxiong Zhou & Huibin Huang. (2023) Research progress on the role and mechanism of action of exosomes in autoimmune thyroid disease. International Reviews of Immunology 42:5, pages 334-346.
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Xiaobin Shang, Yan Fang, Wenqiang Xin & Hongbo You. (2022) The Application of Extracellular Vesicles Mediated miRNAs in Osteoarthritis: Current Knowledge and Perspective. Journal of Inflammation Research 15, pages 2583-2599.
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Articles from other publishers (10)

Juan Zhang, Jin-Qi Liao, Li-Ru Wen, Arshad-Ahmed Padhiar, Zhu Li, Zhong-Yuan He, Hua-Chuan Wu, Jian-Feng Li, Shuai Zhang, Yan Zhou, Xiao-Hua Pan, Jian-Hua Yang & Guang-Qian Zhou. (2023) Rps6ka2 enhances iMSC chondrogenic differentiation to attenuate knee osteoarthritis through articular cartilage regeneration in mice. Biochemical and Biophysical Research Communications 663, pages 61-70.
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Xu Guo, Congying Gao, Dong-Hua Yang & Shenglong Li. (2023) Exosomal circular RNAs: A chief culprit in cancer chemotherapy resistance. Drug Resistance Updates 67, pages 100937.
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Xi Yuan, Junlai Wan, Yang Yang, Long Huang, Chuankun Zhou, Jin Su, Shuaibin Hua, Hongxu Pu, Yi Zou, Hao Zhu, Xulin Jiang & Jun Xiao. (2023) Thermosensitive hydrogel for cartilage regeneration via synergistic delivery of SDF-1α like polypeptides and kartogenin. Carbohydrate Polymers 304, pages 120492.
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Yi Liu, Mintao Xue, Yaguang Han, Yucai Li, Bing Xiao, Weiheng Wang, Jiangming Yu & Xiaojian Ye. (2023) Exosomes from M2c macrophages alleviate intervertebral disc degeneration by promoting synthesis of the extracellular matrix via MiR ‐124/ CILP / TGF ‐β . Bioengineering & Translational Medicine.
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Xiaozhuo Gao, Bo Gao & Shenglong Li. (2022) Extracellular vesicles: A new diagnostic biomarker and targeted drug in osteosarcoma. Frontiers in Immunology 13.
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Chiew Yong Ng, Li Ting Kee, Maimonah Eissa Al-Masawa, Qian Hui Lee, Thayaalini Subramaniam, David Kok, Min Hwei Ng & Jia Xian Law. (2022) Scalable Production of Extracellular Vesicles and Its Therapeutic Values: A Review. International Journal of Molecular Sciences 23:14, pages 7986.
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Li Ting Kee, Chiew Yong Ng, Maimonah Eissa Al-Masawa, Jhi Biau Foo, Chee Wun How, Min Hwei Ng & Jia Xian Law. (2022) Extracellular Vesicles in Facial Aesthetics: A Review. International Journal of Molecular Sciences 23:12, pages 6742.
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Mohd Heikal Mohd Yunus, Yemin Lee, Abid Nordin, Kien Hui Chua & Ruszymah Bt Hj Idrus. (2022) Remodeling Osteoarthritic Articular Cartilage under Hypoxic Conditions. International Journal of Molecular Sciences 23:10, pages 5356.
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Lidia Ibáñez, Paloma Guillem-Llobat, Marta Marín & María Isabel Guillén. (2022) Connection between Mesenchymal Stem Cells Therapy and Osteoclasts in Osteoarthritis. International Journal of Molecular Sciences 23:9, pages 4693.
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Yishu Fan, Zhong Li & Yuchen He. (2022) Exosomes in the Pathogenesis, Progression, and Treatment of Osteoarthritis. Bioengineering 9:3, pages 99.
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