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Journal of Inflammation Research Volume 14, 2021 - Issue

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IGF-1 Facilitates Cartilage Reconstruction by Regulating PI3K/AKT, MAPK, and NF-kB Signaling in Rabbit Osteoarthritis

Mohammad Amjad Hossain1 College of Veterinary Medicine, Biosafety Research Institute, Chonbuk National University, Iksan-city, Jeollabuk-Do, Republic of Korea

https://orcid.org/0000-0001-8941-1065

Aravinthan Adithan1 College of Veterinary Medicine, Biosafety Research Institute, Chonbuk National University, Iksan-city, Jeollabuk-Do, Republic of Korea

Md Jahangir Alam1 College of Veterinary Medicine, Biosafety Research Institute, Chonbuk National University, Iksan-city, Jeollabuk-Do, Republic of Korea

Spandana Rajendra Kopalli2 Department of Integrative Bioscience and Biotechnology, Sejong University, Gwangjin-gu, Seoul, 05006, Republic of Korea

Bumseok Kim1 College of Veterinary Medicine, Biosafety Research Institute, Chonbuk National University, Iksan-city, Jeollabuk-Do, Republic of Korea

Chang-Won Kang1 College of Veterinary Medicine, Biosafety Research Institute, Chonbuk National University, Iksan-city, Jeollabuk-Do, Republic of Korea

Ki-Chul Hwang3 Institute for Bio-Medical Convergence, College of Medicine, Catholic Kwandong University, Gangneung-si, Gangwon-do, Republic of Korea

Jong-Hoon Kim1 College of Veterinary Medicine, Biosafety Research Institute, Chonbuk National University, Iksan-city, Jeollabuk-Do, Republic of KoreaCorrespondence[email protected]

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Pages 3555-3568 | Published online: 24 Jul 2021

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Ling Yang, Xueyuan Yu, Meng Liu & Yang Cao. (2023) A comprehensive analysis of biomarkers associated with synovitis and chondrocyte apoptosis in osteoarthritis. Frontiers in Immunology 14.
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Eduardo Anitua, Roberto Prado, Jorge Guadilla, Mohammad H. Alkhraisat, Patricia Laiz, Sabino Padilla, Montserrat García-Balletbó & Ramón Cugat. (2023) The Dual-Responsive Interaction of Particulated Hyaline Cartilage and Plasma Rich in Growth Factors (PRGF) in the Repair of Cartilage Defects: An In Vitro Study. International Journal of Molecular Sciences 24:14, pages 11581.
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Wei Luo, Zili Lin, Yuhao Yuan, Ziyi Wu, Wei Zhong & Qing Liu. (2023) Osteopontin (OPN) alleviates the progression of osteoarthritis by promoting the anabolism of chondrocytes. Genes & Diseases 10:4, pages 1714-1725.
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Yanqing Liu, Qiong Liu, Zhe Zhang, Yaru Yang, Yazhe Zhou, Huanle Yan, Xin Wang, Xiaoru Li, Jing Zhao, Jingyan Hu, Shulin Yang, Yifan Tian, Yu Yao, Zhenye Qiu, Yanbin Song & Yang Yang. (2023) The regulatory role of PI3K in ageing-related diseases. Ageing Research Reviews 88, pages 101963.
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Sher B. Poudel, Ryan R. Ruff, Gozde Yildirim, Manisha Dixit, Benoit Michot, Jennifer L. Gibbs, Silvana D. Ortiz, John J. Kopchick, Thorsten Kirsch & Shoshana Yakar. (2023) Excess Growth Hormone Triggers Inflammation-Associated Arthropathy, Subchondral Bone Loss, and Arthralgia. The American Journal of Pathology 193:6, pages 829-842.
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Jonah I. Donnenfield, Naga Padmini Karamchedu, Benedikt L. Proffen, Janine Molino, Braden C. Fleming & Martha M. Murray. (2023) Transcriptomic changes in porcine articular cartilage one year following disruption of the anterior cruciate ligament. PLOS ONE 18:5, pages e0284777.
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Sofija Semenistaja, Sandra Skuja, Anda Kadisa & Valerija Groma. (2023) Healthy and Osteoarthritis-Affected Joints Facing the Cellular Crosstalk. International Journal of Molecular Sciences 24:4, pages 4120.
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Armin Vedadghavami, Bill Hakim, Tengfei He & Ambika G. Bajpayee. (2022) Cationic peptide carriers enable long-term delivery of insulin-like growth factor-1 to suppress osteoarthritis-induced matrix degradation. Arthritis Research & Therapy 24:1.
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Yuan Xiong, Bo-Bin Mi, Ze Lin, Yi-Qiang Hu, Le Yu, Kang-Kang Zha, Adriana C. Panayi, Tao Yu, Lang Chen, Zhen-Ping Liu, Anish Patel, Qian Feng, Shuan-Hu Zhou & Guo-Hui Liu. (2022) The role of the immune microenvironment in bone, cartilage, and soft tissue regeneration: from mechanism to therapeutic opportunity. Military Medical Research 9:1.
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Bingbing Wu, Yu Li, Nanfang Nie, Xilin Shen, Wei Jiang, Yanshan Liu, Lin Gong, Chengrui An, Kun Zhao, Xudong Yao, Chunhui Yuan, Jinghui Hu, Wei Zhao, Jianhua Qian & XiaoHui Zou. (2022) SFRP4+ stromal cell subpopulation with IGF1 signaling in human endometrial regeneration. Cell Discovery 8:1.
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Mahsa Sani, Radmarz Hosseinie, Mona Latifi, Mehri Shadi, Mahboobeh Razmkhah, Mahin Salmannejad, Hossein Parsaei & Tahereh Talaei-Khozani. (2022) Engineered artificial articular cartilage made of decellularized extracellular matrix by mechanical and IGF-1 stimulation. Biomaterials Advances 139, pages 213019.
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Yukun Liao, Huiting Jiang, Yangrui Du, Xiaojing Xiong, Yu Zhang & Zhiyu Du. (2022) Using Convolutional Neural Network as a Statistical Algorithm to Explore the Therapeutic Effect of Insulin Liposomes on Corneal Inflammation. Computational Intelligence and Neuroscience 2022, pages 1-9.
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Jaroslav Pejchal, Ales Tichy, Adela Kmochova, Lenka Fikejzlova, Klara Kubelkova, Marcela Milanova, Anna Lierova, Alzbeta Filipova, Lubica Muckova & Jana Cizkova. (2022) Mitigation of Ionizing Radiation-Induced Gastrointestinal Damage by Insulin-Like Growth Factor-1 in Mice. Frontiers in Pharmacology 13.
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Mohammad Amjad Hossain, Md Jahangir Alam, Bumseok Kim, Chang-Won Kang & Jong-Hoon Kim. (2022) Ginsenoside-Rb1 prevents bone cartilage destruction through down-regulation of p-Akt, p-P38, and p-P65 signaling in rabbit. Phytomedicine 100, pages 154039.
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Mudasir Maqbool, Ginenus Fekadu, Xinchan Jiang, Firomsa Bekele, Tadesse Tolossa, Ebisa Turi, Getahun Fetensa & Korinan Fanta. (2021) An up to date on clinical prospects and management of osteoarthritis. Annals of Medicine and Surgery 72, pages 103077.
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DongSheng Pan, Yanhong Lyu, Na Zhang, Xuankang Wang, Tao Lei & Zhuowen Liang. (2021) RIP2 knockdown inhibits cartilage degradation and oxidative stress in IL-1β-treated chondrocytes via regulating TRAF3 and inhibiting p38 MAPK pathway. Clinical Immunology 232, pages 108868.
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IGF-1 Facilitates Cartilage Reconstruction by Regulating PI3K/AKT, MAPK, and NF-kB Signaling in Rabbit Osteoarthritis

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IGF-1 Facilitates Cartilage Reconstruction by Regulating PI3K/AKT, MAPK, and NF-kB Signaling in Rabbit Osteoarthritis

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