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Review

Targeting the NLRP3 inflammasome in chronic inflammatory diseases: current perspectives

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Pages 15-27 | Published online: 16 Jan 2015

Keep up to date with the latest research on this topic with citation updates for this article.

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Jiong Zhang, Juan Chen, Qing Jiang, Rui Feng, Xiaohu Zhao, Haolin Li, Cheng Yang & Xiaoliang Hua. (2023) Resolvin D1 Attenuates Inflammation and Pelvic Pain Associated with EAP by Inhibiting Oxidative Stress and NLRP3 Inflammasome Activation via the Nrf2/HO-1 Pathway. Journal of Inflammation Research 16, pages 3365-3379.
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Yiming Xu, Savannah Biby, Baljit Kaur & Shijun Zhang. (2023) A patent review of NLRP3 inhibitors to treat autoimmune diseases. Expert Opinion on Therapeutic Patents 33:6, pages 455-470.
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Ali Saeedi-Boroujeni, Mohammad-Reza Mahmoudian-Sani, Roohangiz Nashibi, Sheyda Houshmandfar, Sima Tahmaseby Gandomkari & Ali Khodadadi. (2021) Tranilast: a potential anti-Inflammatory and NLRP3 inflammasome inhibitor drug for COVID-19. Immunopharmacology and Immunotoxicology 43:3, pages 247-258.
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Seyed Ahmad Rasoulinejad, Ahmad Karkhah, Alireza Paniri, Kiarash Saleki, Marzieh Pirzadeh & Hamid Reza Nouri. (2020) Contribution of inflammasome complex in inflammatory-related eye disorders and its implications for anti-inflammasome therapy. Immunopharmacology and Immunotoxicology 42:5, pages 400-407.
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Hanna Pawluk, Alina Woźniak, Grzegorz Grześk, Renata Kołodziejska, Mariusz Kozakiewicz, Ewa Kopkowska, Elżbieta Grzechowiak & Grzegorz Kozera. (2020) The Role of Selected Pro-Inflammatory Cytokines in Pathogenesis of Ischemic Stroke. Clinical Interventions in Aging 15, pages 469-484.
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Mahdi Gouravani, Nastaran Khalili, Sepideh Razi, Mahsa Keshavarz-Fathi, Neda Khalili & Nima Rezaei. (2020) The NLRP3 inflammasome: a therapeutic target for inflammation-associated cancers. Expert Review of Clinical Immunology 16:2, pages 175-187.
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Yue Sun, Yan-Qiu Zhou, Yin-Kai Liu, Hong-Qin Zhang, Gui-Ge Hou, Qing-Guo Meng & Yun Hou. (2020) Potential anti-neuroinflammatory NF-кB inhibitors based on 3,4-dihydronaphthalen-1(2H)-one derivatives. Journal of Enzyme Inhibition and Medicinal Chemistry 35:1, pages 1631-1640.
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Gang Xu, Jian Wang, Long Ma, Xin Zhao, Wen Luo & Qunhua Jin. (2019) Local intra-articular injection of rapamycin inhibits NLRP3 activity and prevents osteoarthritis in mouse DMM models. Autoimmunity 52:4, pages 168-175.
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