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Review

Tapentadol for neuropathic pain: a review of clinical studies

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Pages 1537-1551 | Published online: 16 May 2019

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (6)

Fahad S Alshehri. (2023) Tapentadol: A Review of Experimental Pharmacology Studies, Clinical Trials, and Recent Findings. Drug Design, Development and Therapy 17, pages 851-861.
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Kazutaka Nozawa, Yusuke Karasawa, Yuka Shidahara & Takahiro Ushida. (2022) Efficacy of Combination Therapy with Pregabalin in Neuropathic Pain: A Preclinical Study in the Rat L5 Spinal Nerve Ligation Model. Journal of Pain Research 15, pages 3469-3478.
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Marc S. Rendell. (2021) The time to develop treatments for diabetic neuropathy. Expert Opinion on Investigational Drugs 30:2, pages 119-130.
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Shazli Azmi, Uazman Alam, Jamie Burgess & Rayaz A. Malik. (2021) State-of-the-art pharmacotherapy for diabetic neuropathy. Expert Opinion on Pharmacotherapy 22:1, pages 55-68.
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Filippo Caraci, Flaminia Coluzzi, Franco Marinangeli, Sebastiano Mercadante, Giuseppe Rinonapoli, Patrizia Romualdi, Mariaflavia Nicora & Anthony H. Dickenson. (2020) Modulation of sensitization processes in the management of pain and the importance of descending pathways: a role for tapentadol?. Current Medical Research and Opinion 36:6, pages 1015-1024.
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Filippo Caraci, Flaminia Coluzzi, Franco Marinangeli, Sebastiano Mercadante, Giuseppe Rinonapoli, Patrizia Romualdi, Mariaflavia Nicora & Anthony H. Dickenson. (2020) Modulation of sensitization processes in the management of pain and the importance of descending pathways: a role for tapentadol?. Current Medical Research and Opinion 36:5, pages (I)-(XVII).
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Florine M. Wiss, Céline K. Stäuble, Henriette E. Meyer zu Schwabedissen, Samuel S. Allemann & Markus L. Lampert. (2023) Pharmacogenetic Analysis Enables Optimization of Pain Therapy: A Case Report of Ineffective Oxycodone Therapy. Journal of Personalized Medicine 13:5, pages 829.
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Frederic J. F. Viseux, Arnaud Delval, Martin Simoneau & Luc Defebvre. (2023) Pain and Parkinson's disease: Current mechanism and management updates. European Journal of Pain 27:5, pages 553-567.
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Joseph Pergolizzi, Giustino Varrassi, Jo Ann K LeQuang, Frank Breve & Peter Magnusson. (2023) Fixed Dose Versus Loose Dose: Analgesic Combinations. Cureus.
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Pasquale Sansone, Luca Gregorio Giaccari, Caterina Aurilio, Francesco Coppolino, Maria Beatrice Passavanti, Vincenzo Pota & Maria Caterina Pace. (2022) Comparative Efficacy of Tapentadol versus Tapentadol Plus Duloxetine in Patients with Chemotherapy-Induced Peripheral Neuropathy (CIPN): A Randomized Non-Inferiority Clinical Trial. Cancers 14:16, pages 4002.
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Sasha Smith, Pasha Normahani, Tristan Lane, David Hohenschurz-Schmidt, Nick Oliver & Alun Huw Davies. (2022) Prevention and Management Strategies for Diabetic Neuropathy. Life 12:8, pages 1185.
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Shane Darke, Johan Duflou, Amy Peacock, Michael Farrell & Julia Lappin. (2022) Characteristics of fatal tapentadol‐related toxicity in Australia. Drug and Alcohol Review 41:5, pages 1071-1077.
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Celia García-López, Carmen Gómez-Huertas, José-María Sánchez-González, Davide Borroni, Marina Rodríguez-Calvo-de-Mora, Vito Romano, Rahul Rachwani-Anil, Juan-Francisco Ramos-López, Santiago Ortiz-Pérez & Carlos Rocha-de-Lossada. (2022) Opioids and Ocular Surface Pathology: A Literature Review of New Treatments Horizons. Journal of Clinical Medicine 11:5, pages 1424.
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Zunaira Qureshi, Murtaza Najabat Ali & Minahil Khalid. (2022) An Insight into Potential Pharmacotherapeutic Agents for Painful Diabetic Neuropathy. Journal of Diabetes Research 2022, pages 1-19.
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Charlotte Heldreich, Ilonka Meyer, Esther Dube, Raymond Hu, William Howard, Natasha Holmes, Nada Maroon, Laurence Weinberg & Chong O. Tan. (2022) Peri-OPerative Pain Management, Education & De-escalation (POPPMED), a novel anaesthesiologist-led program, significantly reduces acute and long-term postoperative opioid requirements: a retrospective cohort study. PAIN Reports 7:5, pages e1028.
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Annas Aljassem, Levi M. Hall, Michael Spickler & Daniel L. Menkes. 2022. Neuromuscular Disorders. Neuromuscular Disorders 118 142 .
L. Brullot, G. Hans, P.J. Germonpré, D. Mesotten, T. Vanneste & K. Van Boxem. (2021) Retrospectieve praktijkanalyse van tapentadol met vertraagde afgifte bij patiënten met chronische pijn refractair aan sterke opioïden. Tijdschrift voor Geneeskunde.
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Suganthiya S. Croosu, Jens B. Frøkjær, Asbjørn M. Drewes & Tine M. Hansen. (2021) Tapentadol and oxycodone affect resting‐state functional brain connectivity: A randomized, placebo‐controlled trial. Journal of Neuroimaging 31:5, pages 956-961.
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Marion Ferner & Rita Laufenberg-Feldmann. (2021) Neuropathischer Schmerz bei Palliativpatienten. Zeitschrift für Palliativmedizin 22:05, pages 271-282.
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Maren Reimer, Juliane Sachau, Julia Forstenpointner & Ralf Baron. (2021) Bedside testing for precision pain medicine. Current Opinion in Supportive & Palliative Care 15:2, pages 116-124.
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Mayank Gupta, Nebojsa Nick Knezevic, Alaa Abd-Elsayed, Mahoua Ray, Kiran Patel & Bhavika Chowdhury. (2021) Treatment of Painful Diabetic Neuropathy—A Narrative Review of Pharmacological and Interventional Approaches. Biomedicines 9:5, pages 573.
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Ulderico Freo, Viola Brugnatelli, Fabio Turco & Gastone Zanette. (2021) Analgesic and Antidepressant Effects of the Clinical Glutamate Modulators Acetyl-L-Carnitine and Ketamine. Frontiers in Neuroscience 15.
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Ulderico Freo, Maurizio Furnari, Francesco Ambrosio & Paolo Navalesi. (2020) Efficacy and tolerability of tapentadol for the treatment of chronic low back pain in elderly patients. Aging Clinical and Experimental Research 33:4, pages 973-982.
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Kavi Haji, Sachin Muthu, Iouri Banakh & Ravindranath Tiruvoipati. (2021) Prolonged encephalopathy and associated nonconvulsive seizures from suspected pregabalin and tapentadol: Two case reports and review of literature. Clinical Case Reports 9:3, pages 1362-1366.
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Alfonso ORIENTE, Elsa MAZZARELLA & Antonio DEL PUENTE. (2021) Effectiveness and tolerability of tapentadol PR in the management of vertebral fracture pain due to bone fragility. Minerva Ortopedica e Traumatologica 71:4.
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Ankita Sood, Bimlesh Kumar, Sachin Kumar Singh, Pankaj Prashar, Anamika Gautam, Monica Gulati, Narendra Kumar Pandey, Indu Melkani, Ankit Awasthi, Subhini A Saraf, Giovani Vidari, Mehmet Ozdemir, Faiq Hama Saeed Hussain, Esra Tariq Anwar, Muath Sheet Mohammed Ameen, Saurabh Gupta & Omji Porwal. (2020) Flavonoids as Potential Therapeutic Agents for the Management of Diabetic Neuropathy. Current Pharmaceutical Design 26:42, pages 5468-5487.
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Gabriele Finco, Maurizio Evangelista & Salvatore Sardo. (2020) Basic guide to chronic pain assessment: from neurophysiology to bedside. Minerva Anestesiologica 86:12.
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Shoichiro Sazuka & Toshiya Koitabashi. (2020) Tapentadol is effective in the management of moderate-to-severe cancer-related pain in opioid-naïve and opioid-tolerant patients: a retrospective study. Journal of Anesthesia 34:6, pages 834-840.
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Amanda C. Peltier & Derek Wood. (2020) Management of Neuropathic Pain in Polyneuropathy. CONTINUUM: Lifelong Learning in Neurology 26:5, pages 1299-1322.
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Pasquale Linciano, Giacomo Rossino, Roberta Listro, Daniela Rossi & Simona Collina. (2020) Sigma-1 receptor antagonists: promising players in fighting neuropathic pain. Pharmaceutical Patent Analyst 9:3, pages 77-85.
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Daniela C. Rosenberger, Vivian Blechschmidt, Hans Timmerman, André Wolff & Rolf-Detlef Treede. (2020) Challenges of neuropathic pain: focus on diabetic neuropathy. Journal of Neural Transmission 127:4, pages 589-624.
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Praveen Anand, Anthony Dickenson, Gabriele Finco, Franco Marinangeli, Enrico Polati, Patrizia Romualdi, Thomas M Tzschentke & Pier Luigi Canonico. (2019) Novel insights on the management of pain: highlights from the ‘Science of Relief’ meeting. Pain Management 9:6, pages 521-533.
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Nurcan Üçeyler. (2019) Schmerzbehandlung bei diabetischer PolyneuropathiePain treatment in diabetic polyneuropathy. Der Diabetologe 15:7, pages 647-652.
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