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Original Research

Development of opioid-induced constipation: post hoc analysis of data from a 12-week prospective, open-label, blinded-endpoint streamlined study in low-back pain patients treated with prolonged-release WHO step III opioids

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Pages 459-475 | Published online: 10 Aug 2015

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (3)

Carsten Bantel, Shiva S Tripathi, David Molony, Tony Heffernan, Susmita Oomman, Vivek Mehta & Sara Dickerson. (2018) Prolonged-release oxycodone/naloxone reduces opioid-induced constipation and improves quality of life in laxative-refractory patients: results of an observational study. Clinical and Experimental Gastroenterology 11, pages 57-67.
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Michael A Ueberall, Alice Eberhardt & Gerhard HH Mueller-Schwefe. (2016) Quality of life under oxycodone/naloxone, oxycodone, or morphine treatment for chronic low back pain in routine clinical practice. International Journal of General Medicine 9, pages 39-51.
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Mellar P. Davis. (2016) Pharmacokinetic and pharmacodynamic evaluation of oxycodone and naltrexone for the treatment of chronic lower back pain. Expert Opinion on Drug Metabolism & Toxicology 12:7, pages 823-831.
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Articles from other publishers (8)

Michael A. Überall & Gerhard H. H. Müller-Schwefe. (2019) Keine Evidenz für die Abschwächung der analgetischen Opioidwirkung durch peripher wirksame µ‑OpioidrezeptorantagonistenLack of evidence for the inhibition of opioid-related analgesia through peripherally acting μ‑opioid-receptor antagonists. Der Schmerz 34:1, pages 84-85.
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Bart J. Morlion, Stefan A. Mueller-Lissner, Renato Vellucci, Wojciech Leppert, Benoît C. Coffin, Sara L. Dickerson & Tony O'Brien. (2018) Oral Prolonged-Release Oxycodone/Naloxone for Managing Pain and Opioid-Induced Constipation: A Review of the Evidence. Pain Practice 18:5, pages 647-665.
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Michael A. Überall, Oliver M. D. Emrich & Gerhard H. H. Müller-Schwefe. (2017) Wirksamkeit und Verträglichkeit von Methocarbamol bei muskulär bedingten subakuten Kreuz-/RückenschmerzenReal-life efficacy and tolerability of methocarbamol in patients suffering from refractory muscle-related low/back pain — Results of a health care research project based on data from the German pain practice registry. MMW - Fortschritte der Medizin 159:S7, pages 6-17.
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Richard J. Bodnar. (2017) Endogenous Opiates and Behavior: 2015. Peptides 88, pages 126-188.
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Magdalena Kocot-KępskaRenata ZajączkowskaAnna Przeklasa-MuszyńskaJan Dobrogowski. (2017) The role of oxycodone/naloxone in pain management. BÓL 17:4, pages 26-40.
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Richard Lawson, Frederic King, Kevin Marsh, Arman Altincatal & Ali Cimen. (2016) Impact of Treatment with Naloxegol for Opioid-Induced Constipation on Patients’ Health State Utility. Advances in Therapy 33:8, pages 1331-1346.
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Paula Mosińska, Marta Zielińska & Jakub Fichna. (2016) Expression and physiology of opioid receptors in the gastrointestinal tract. Current Opinion in Endocrinology, Diabetes & Obesity 23:1, pages 3-10.
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MA Ueberall. (2015) Differential Gastrointestinal Effects of Who-Step III Opioids in Low Back Pain Patients with vs. Without Constipation: Post-Hoc Analysis of Data from a 12-Week Prospective, Open-Label Blinded Endpoint Streamlined Study. Global Journal of Anesthesiology, pages 037-051.
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