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REVIEW

Practical guidance for the use of cyclosporine ophthalmic solutions in the management of dry eye disease

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Pages 1115-1122 | Published online: 01 Jul 2019

Keep up to date with the latest research on this topic with citation updates for this article.

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Alejandro Rodriguez-Garcia, Alejandro Babayan-Sosa, Arturo Ramirez-Miranda, Concepcion Santa Cruz-Valdes, Everardo Hernandez-Quintela, Julio C Hernandez-Camarena, Nallely Ramos-Betancourt, Regina Velasco-Ramos & Raul E Ruiz-Lozano. (2022) A Practical Approach to Severity Classification and Treatment of Dry Eye Disease: A Proposal from the Mexican Dry Eye Disease Expert Panel. Clinical Ophthalmology 16, pages 1331-1355.
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Wenyan Peng, Xiuying Jiang, Lei Zhu, Xiaofeng Li, Qizhi Zhou, Ying Jie, Zhipeng You, Miaoqin Wu, Xiuming Jin, Xiaoyi Li & Shiyou Zhou. (2022) Cyclosporine A (0.05%) Ophthalmic Gel in the Treatment of Dry Eye Disease: A Multicenter, Randomized, Double-Masked, Phase III, COSMO Trial. Drug Design, Development and Therapy 16, pages 3183-3194.
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Laura M Periman, Francis S Mah & Paul M Karpecki. (2020) A Review of the Mechanism of Action of Cyclosporine A: The Role of Cyclosporine A in Dry Eye Disease and Recent Formulation Developments. Clinical Ophthalmology 14, pages 4187-4200.
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Articles from other publishers (14)

Elisabeth M Messmer, Sajjad Ahmad, José M Benitez del Castillo, Ewa Mrukwa-Kominek, Maurizio Rolando, Oksana Vitovska & Christophe Baudouin. (2022) Management of inflammation in dry eye disease: Recommendations from a European panel of experts. European Journal of Ophthalmology 33:3, pages 1294-1307.
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Desti Priani, Habibah S. Muhiddin, Junaedi Sirajuddin, Hasnah B. Eka, Burhanuddin Bahar & Agussalim Bukhari. (2023) Effectiveness of Topical Cyclosporin-A 0.1% Compared to Combined Topical Cyclosporin-A 0.1% with Topical Sodium Hyaluronate on Interleukin-6 Levels in the Tears of Patients with Dry Eye Disease. Vision 7:2, pages 31.
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Ka-Ying Wong, Yibo Liu, Liping Zhou, Man-Sau Wong & Juewen Liu. (2023) Mucin-targeting-aptamer functionalized liposomes for delivery of cyclosporin A for dry eye diseases. Journal of Materials Chemistry B.
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Sanaz Sadig Baheran, Raid G. Alany, Sianne Schwikkard, Wisam Muen, Lena Namaan Salman, Nicholas Freestone & Ali A. Al-Kinani. (2023) Pharmacological treatment strategies of pterygium: Drugs, biologics, and novel natural products. Drug Discovery Today 28:1, pages 103416.
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Ji Eun Lee, Sangyoon Kim, Hyung Keun Lee, Tae-Young Chung, Jae Yong Kim, Chul Young Choi, So Hyang Chung, Dong Hyun Kim, Kyoung Woo Kim, Jin Kwon Chung, Kyu Yeon Hwang, Ho Sik Hwang, Jin Hyoung Kim & Joon Young Hyon. (2022) A randomized multicenter evaluation of the efficacy of 0.15% hyaluronic acid versus 0.05% cyclosporine A in dry eye syndrome. Scientific Reports 12:1.
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Yanfang Zhai, Xiaoxiang Zheng, Yunyun Mao, Kai Li, Yanhong Liu, Yuemei Gao, Mengsu Zhao, Rui Yang, Rui Yu & Wei Chen. (2022) Recombinant Human Thymosin β4 (rhTβ4) Modulates the Anti-Inflammatory Responses to Alleviate Benzalkonium Chloride (BAC)-Induced Dry Eye Disease. International Journal of Molecular Sciences 23:10, pages 5458.
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C: Banu COŞAR, Ayşe Ebru KILAVUZOĞLU, Ali Riza Cenk CELEBİ & Uğur Emrah ALTIPARMAK. (2022) Generic Cyclosporine in the Treatment of Dry Eye Disease. Acibadem Universitesi Saglik Bilimleri Dergisi 13:2.
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A. A. Panov, A. A. Petukhova, Ya. V. Malygin, B. D. Tsygankov & M. A. Kazanfarova. (2022) Adverse ocular effects of neuroleptic therapy: semiotics, pathogenesis and treatment. Russian Ophthalmological Journal 14:4, pages 172-178.
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Rujun Jin, Ying Li, Lan Li, Jonghwa Kim, Hyeon Yoon & Kyung Yoon. (2021) Comparative analysis of 0.1% cyclosporin A cationic emulsion and 0.05% cyclosporin A emulsion in murine dry eye cases with different severities. Experimental and Therapeutic Medicine 22:6.
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Lubna M. Eldesouky, Riham M. El-Moslemany, Alyaa A. Ramadan, Mahmoud H. Morsi & Nawal M. Khalafallah. (2021) Cyclosporine Lipid Nanocapsules as Thermoresponsive Gel for Dry Eye Management: Promising Corneal Mucoadhesion, Biodistribution and Preclinical Efficacy in Rabbits. Pharmaceutics 13:3, pages 360.
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Jeongah ShinChang Rae RhoJoon Young HyonTae-Young ChungKyung Chul YoonChoun-Ki Joo. (2021) A Randomized, Placebo-Controlled Phase II Clinical Trial of 0.01% or 0.02% Cyclosporin A with 3% Trehalose in Patients with Dry Eye Disease. Journal of Ocular Pharmacology and Therapeutics 37:1, pages 4-11.
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Carla S. Medeiros & Marcony R. Santhiago. (2020) Corneal nerves anatomy, function, injury and regeneration. Experimental Eye Research 200, pages 108243.
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Rujun Jin, Ying Li, Lan Li, Dong Hwan Kim, Che Dong Yang, Han Sun Son, Jung Han Choi, Hyeon Jeong Yoon & Kyung Chul Yoon. (2020) Anti‑inflammatory effects of glycine thymosin�β4 eye drops in experimental dry eye. Biomedical Reports.
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Inna A. Riks. (2019) Cyclosporine use in “dry eye” syndrome. Ophthalmology Reports 12:3, pages 75-82.
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