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Airway biomarkers of the oxidant burden in asthma and chronic obstructive pulmonary disease: Current and future perspectives

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Pages 585-603 | Published online: 05 Dec 2008

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (11)

Mohammed K. Еlmahdy, Rania R. Abdelaziz, Hoda S. Elmahdi & Ghada M. Suddеk. (2022) Effect of Agmatine on a mouse model of allergic airway inflammation: A comparative study. Autoimmunity 55:8, pages 608-619.
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Deepa K. Ingawale, Satish K. Mandlik & Snehal S. Patel. (2020) Combination of Sarsasapogenin and Fluticasone attenuates ovalbumin-induced airway inflammation in a mouse asthma model. Immunopharmacology and Immunotoxicology 42:2, pages 128-137.
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Ji-Yong Moon, Fernando Sergio Leitao Filho, Kimeya Shahangian, Hiroto Takiguchi & Don D. Sin. (2018) Blood and sputum protein biomarkers for chronic obstructive pulmonary disease (COPD). Expert Review of Proteomics 15:11, pages 923-935.
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Balazs Antus, Csilla Paska, Beatrix Simon & Imre Barta. (2018) Monitoring Antioxidant Enzyme Activity during Exacerbations of Chronic Obstructive Pulmonary Disease. COPD: Journal of Chronic Obstructive Pulmonary Disease 15:5, pages 496-502.
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Bernard M Fischer, Judith A Voynow & Andrew J Ghio. (2015) COPD: balancing oxidants and antioxidants. International Journal of Chronic Obstructive Pulmonary Disease 10, pages 261-276.
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Wolfgang Domej, Karl Oettl & Wilfried Renner. (2014) Oxidative stress and free radicals in COPD – implications and relevance for treatment. International Journal of Chronic Obstructive Pulmonary Disease 9, pages 1207-1224.
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Robert A Stockley. (2014) Biomarkers in chronic obstructive pulmonary disease: confusing or useful?. International Journal of Chronic Obstructive Pulmonary Disease 9, pages 163-177.
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Irfan Rahman & Vuokko L Kinnula. (2012) Strategies to decrease ongoing oxidant burden in chronic obstructive pulmonary disease. Expert Review of Clinical Pharmacology 5:3, pages 293-309.
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Alessandra Atzei, Luigi Atzori, Corrado Moretti, Luigi Barberini, Antonio Noto, Giovanni Ottonello, Elisabetta Pusceddu & Vassilios Fanos. (2011) Metabolomics in paediatric respiratory diseases and bronchiolitis. The Journal of Maternal-Fetal & Neonatal Medicine 24:sup2, pages 59-62.
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Kanami Orihara, Nyla Dil, Vidyanand Anaparti & Redwan Moqbel. (2010) What’s new in asthma pathophysiology and immunopathology?. Expert Review of Respiratory Medicine 4:5, pages 605-629.
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A Boutten, D Goven, J Boczkowski & M Bonay. (2010) Oxidative stress targets in pulmonary emphysema: focus on the Nrf2 pathway. Expert Opinion on Therapeutic Targets 14:3, pages 329-346.
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Articles from other publishers (32)

Luiz H. C. Vasconcelos, Sarah R. D. Ferreira, Maria da C. C. Silva, Paula B. Ferreira, Iara L. L. de Souza, Fabiana de A. Cavalcante & Bagnólia A. da Silva. (2021) Uncovering the Role of Oxidative Imbalance in the Development and Progression of Bronchial Asthma. Oxidative Medicine and Cellular Longevity 2021, pages 1-9.
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Erin Beattie, Jeffery Edmiston, Patrudu Makena, Elizabeth Mason, Mike McEwan & Krishna Prasad. (2021) Review of recent lung biomarkers of potential harm/effect for tobacco research. F1000Research 10, pages 1293.
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Zekun Liu, Qi Zhao, Zhi-Xiang Zuo, Shu-Qiang Yuan, Kai Yu, Qingfeng Zhang, Xiaolong Zhang, Hui Sheng, Huai-Qiang Ju, Han Cheng, Feng Wang, Rui-Hua Xu & Ze-Xian Liu. (2020) Systematic Analysis of the Aberrances and Functional Implications of Ferroptosis in Cancer. iScience 23:7, pages 101302.
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Marianne Riou, Abrar Alfatni, Anne-Laure Charles, Emmanuel Andrès, Cristina Pistea, Anne Charloux & Bernard Geny. (2020) New Insights into the Implication of Mitochondrial Dysfunction in Tissue, Peripheral Blood Mononuclear Cells, and Platelets during Lung Diseases. Journal of Clinical Medicine 9:5, pages 1253.
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Ederlé, Charles, Khayath, Poirot, Meyer, Clere-Jehl, Andres, Blay & Geny. (2019) Mitochondrial Function in Peripheral Blood Mononuclear Cells (PBMC) Is Enhanced, Together with Increased Reactive Oxygen Species, in Severe Asthmatic Patients in Exacerbation. Journal of Clinical Medicine 8:10, pages 1613.
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Jinrui Dong, Wupeng Liao, Hong Yong Peh, W.S. Daniel Tan, Shuo Zhou & W.S. Fred Wong. (2018) Ribosomal Protein S3 Gene Silencing Protects Against Cigarette Smoke-Induced Acute Lung Injury. Molecular Therapy - Nucleic Acids 12, pages 370-380.
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A. Villaseñor, D. Rosace, D. Obeso, M. Pérez-Gordo, T. Chivato, C. Barbas, D. Barber & M. M. Escribese. (2017) Allergic asthma: an overview of metabolomic strategies leading to the identification of biomarkers in the field. Clinical & Experimental Allergy 47:4, pages 442-456.
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A Herrejon, J Palop, S Herrera & A Betancurt. (2017) Utility Inspiratory Capacity by Simple Spirometry as an indirect Measure of Air Trapping. Archives of Pulmonology and Respiratory Care 3:1, pages 007-010.
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C Cristóvão, L Cristóvão, F Nogueira & M Bicho. (2017) Oxidative Stress, Antioxidant Status and Inflammation in Chronic Bronchitis and Pulmonary Emphysema. Archives of Pulmonology and Respiratory Care 3:1, pages 001-006.
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Ville Vartiainen, Luis M. Bimbo, Jouni Hirvonen, Esko I. Kauppinen & Janne Raula. (2016) Drug permeation and cellular interaction of amino acid-coated drug combination powders for pulmonary delivery. International Journal of Pharmaceutics 504:1-2, pages 89-97.
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Wei Gao, Cheng Yuan, Jingying Zhang, Lingling Li, Like Yu, Coen H. WiegmanPeter J. BarnesIan M. AdcockMao Huang & Xin Yao. (2015) Klotho expression is reduced in COPD airway epithelial cells: effects on inflammation and oxidant injury. Clinical Science 129:12, pages 1011-1023.
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Miroslav Radulovic, William A Bauman, Jill M Wecht, Michael LaFountaine, Nighat Kahn, Joshua Hobson, Kamaldeep Singh, Christopher Renzi, Christina Yen & Gregory J Schilero. (2015) Biomarkers of inflammation in persons with chronic tetraplegia. Journal of Breath Research 9:3, pages 036001.
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David S.W. Ng, Wupeng Liao, W.S. Daniel Tan, Tze Khee Chan, Xin Yi Loh & W.S. Fred Wong. (2014) Anti-malarial drug artesunate protects against cigarette smoke-induced lung injury in mice. Phytomedicine 21:12, pages 1638-1644.
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Rama Malaviya, Jeffrey D. Laskin & Debra L. Laskin. (2014) Oxidative stress-induced autophagy: Role in pulmonary toxicity. Toxicology and Applied Pharmacology 275:2, pages 145-151.
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Nadezhda P. Palmina, Elena L. Maltseva, Tatyana E. Chasovskaya, Valery V. Kasparov, Nataliya G. Bogdanova, Valery A. Menshov & Aleksei V. Trofimov. (2014) Effects of Different Phases of Cigarette Smoke on Lipid Peroxidation and Membrane Structure in Liposomes. Australian Journal of Chemistry 67:6, pages 858.
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R.C. Rebolledo-Cobos, B. Teixeira & C. Correa. (2014) Asma, estrés oxidativo y ejercicio físico: revisión de la literatura. Fisioterapia 36:1, pages 40-48.
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SP Guan, W Tee, DSW Ng, TK Chan, HY Peh, WE Ho, C Cheng, JC Mak & WSF Wong. (2013) Andrographolide protects against cigarette smoke-induced oxidative lung injury via augmentation of Nrf2 activity. British Journal of Pharmacology 168:7, pages 1707-1718.
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Olawunmi A. Ajibola, David Smith, Patrik Španěl & Gordon A. A. Ferns. (2013) Effects of dietary nutrients on volatile breath metabolites. Journal of Nutritional Science 2.
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Gennadii Kamarchuk, Alexander Pospelov & Ievgeniia Kushch. 2013. Volatile Biomarkers. Volatile Biomarkers 264 300 .
Honggang Wang, William B Mattes, Patricia Richter & Donna L Mendrick. (2012) An omics strategy for discovering pulmonary biomarkers potentially relevant to the evaluation of tobacco products. Biomarkers in Medicine 6:6, pages 849-860.
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C Rossios, Y To, G Osoata, M Ito, PJ Barnes & K Ito. (2012) Corticosteroid insensitivity is reversed by formoterol via phosphoinositide-3-kinase inhibition. British Journal of Pharmacology 167:4, pages 775-786.
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Mayyasa Rammah, Farah Dandachi, Rola Salman, Alan Shihadeh & Marwan El-Sabban. (2012) In vitro cytotoxicity and mutagenicity of mainstream waterpipe smoke and its functional consequences on alveolar type II derived cells. Toxicology Letters 211:3, pages 220-231.
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Se-Ran Yang, Irfan Rahman, James E. Trosko & Kyung-Sun Kang. (2012) Oxidative stress-induced biomarkers for stem cell-based chemical screening. Preventive Medicine 54, pages S42-S49.
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Heikki O. Koskela, Minna K. Purokivi, Riina M. Nieminen & Eeva Moilanen. (2012) Asthmatic cough and airway oxidative stress. Respiratory Physiology & Neurobiology 181:3, pages 346-350.
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Elia Mattarucchi, Eugenio Baraldi & Claude Guillou. (2012) Metabolomics applied to urine samples in childhood asthma; differentiation between asthma phenotypes and identification of relevant metabolites. Biomedical Chromatography 26:1, pages 89-94.
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Nobuhisa Ishikawa, Witold Mazur, Tuula Toljamo, Katri Vuopala, Mikko Rönty, Yasushi Horimasu, Nobuoki Kohno & Vuokko L Kinnula. (2011) Ageing and long-term smoking affects KL-6 levels in the lung, induced sputum and plasma. BMC Pulmonary Medicine 11:1.
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Serena E. O'Neil, Bo Lundbäck & Jan Lötvall. (2011) Proteomics in asthma and COPD phenotypes and endotypes for biomarker discovery and improved understanding of disease entities. Journal of Proteomics 75:1, pages 192-201.
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Joanne H Shorter, David D Nelson, J Barry McManus, Mark S Zahniser, Susan R Sama & Donald K Milton. (2011) Clinical study of multiple breath biomarkers of asthma and COPD (NO, CO 2 , CO and N 2 O) by infrared laser spectroscopy . Journal of Breath Research 5:3, pages 037108.
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Natalia D. Magnani, Timoteo Marchini, Deborah R. Tasat, Silvia Alvarez & Pablo A. Evelson. (2011) Lung oxidative metabolism after exposure to ambient particles. Biochemical and Biophysical Research Communications 412:4, pages 667-672.
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Melissa D. Blank, Caroline O. Cobb, Barbara Kilgalen, Janet Austin, Michael F. Weaver, Alan Shihadeh & Thomas Eissenberg. (2011) Acute effects of waterpipe tobacco smoking: A double-blind, placebo-control study. Drug and Alcohol Dependence 116:1-3, pages 102-109.
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R. Capuano, M. Santonico, E. Martinelli, G. Pennazza, R. Paolesse, A. Bergamini, M. Cazzola, C. Ciaprini, C. Di Natale & A. D’Amico. (2010) COPD diagnosis by a gas sensor array. Procedia Engineering 5, pages 484-487.
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R.-M. Liu & K.A. Gaston Pravia. (2010) Oxidative stress and glutathione in TGF-β-mediated fibrogenesis. Free Radical Biology and Medicine 48:1, pages 1-15.
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