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Review

Recent advances in neutralizing the IL-6 pathway in arthritis

Pages 133-150 | Published online: 06 Oct 2009

Keep up to date with the latest research on this topic with citation updates for this article.

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Evan C Meszaros & Charles J Malemud. (2017) Phosphorylation of STAT proteins by recombinant human IL-6 in immortalized human chondrocyte cell lines, T/C28a2 and C28/I2. Journal of Inflammation Research 10, pages 143-150.
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Charles J Malemud. (2010) Differential activation of JAK enzymes in rheumatoid arthritis and autoimmune disorders by pro-inflammatory cytokines: potential drug targets. International Journal of Interferon, Cytokine and Mediator Research 2, pages 97-111.
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Articles from other publishers (11)

Zixuan Zhao, Zhenglai Hua, Xinyi Luo, Yang Li, Liuchunyang Yu, Ming Li, Cheng Lu, Ting Zhao & Yuanyan Liu. (2022) Application and pharmacological mechanism of methotrexate in rheumatoid arthritis. Biomedicine & Pharmacotherapy 150, pages 113074.
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Da Hyeon Choi, Dongwoo Lee, Beom Soo Jo, Kwang-Sook Park, Kyeong Eun Lee, Ju Kwang Choi, Yoon Jeong Park, Jue-Yeon Lee & Yoon Shin Park. (2020) A Synthetic Cell-Penetrating Heparin-Binding Peptide Derived from BMP4 with Anti-Inflammatory and Chondrogenic Functions for the Treatment of Arthritis. International Journal of Molecular Sciences 21:12, pages 4251.
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Lijuan Zhu, Zhenshan Zhang, Nannan Xia, Weifeng Zhang, Yanlin Wei, Jiashu Huang, Zhijuan Ren, Feilong Meng & Lei Yang. (2019) Anti-arthritic activity of ferulic acid in complete Freund’s adjuvant (CFA)-induced arthritis in rats: JAK2 inhibition. Inflammopharmacology 28:2, pages 463-473.
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Elvira Lazić Mosler, Nina Lukač, Darja Flegar, Martina Fadljević, Igor Radanović, Hrvoje Cvija, Tomislav Kelava, Sanja Ivčević, Alan Šućur, Antonio Markotić, Vedran Katavić, Ana Marušić, Danka Grčević & And Nataša Kovačić. (2018) Fas receptor induces apoptosis of synovial bone and cartilage progenitor populations and promotes bone loss in antigen‐induced arthritis. The FASEB Journal 33:3, pages 3330-3342.
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Sotonye Imadojemu & Misha Rosenbach. (2019) Advances in Inflammatory Granulomatous Skin Diseases. Dermatologic Clinics 37:1, pages 49-64.
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Charles J. Malemud. 2018. Drug Discovery - Concepts to Market. Drug Discovery - Concepts to Market.
Charles J. Malemud. (2018) The role of the JAK/STAT signal pathway in rheumatoid arthritis. Therapeutic Advances in Musculoskeletal Disease 10:5-6, pages 117-127.
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Evan Meszaros & Charles J. Malemud. (2012) Prospects for treating osteoarthritis: enzyme–protein interactions regulating matrix metalloproteinase activity. Therapeutic Advances in Chronic Disease 3:5, pages 219-229.
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Charles J Malemud. (2012) Inhibitors of JAK for the treatment of rheumatoid arthritis: rationale and clinical data. Clinical Investigation 2:1, pages 39-47.
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Jinqi Liu & Huseyin Mehmet. (2011) Emerging therapies in the treatment of rheumatoid arthritis. Drug Development Research 72:8, pages 805-816.
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Charles J. Malemud. (2010) Suppression of Autoimmune Arthritis by Small Molecule Inhibitors of the JAK/STAT Pathway. Pharmaceuticals 3:5, pages 1446-1455.
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