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Acta Oto-Laryngologica Volume 130, 2010 - Issue 10
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Ginkgo biloba extract (EGb761) protects against aging-related caspase-mediated apoptosis in rat cochlea

Julián Nevado
,
Ricardo Sanz Servicio de Otorrinolaringología y Unidad de Investigación, Hospital Universitario de Getafe, Getafe (Madrid), SpainCorrespondence[email protected]
,
Carolina Sánchez-Rodríguez Servicio de Otorrinolaringología y Unidad de Investigación, Hospital Universitario de Getafe, Getafe (Madrid), Spain
,
José Ramón García-Berrocal Servicio de Otorrinolaringología, Hospital Universitario Puerta de Hierro-Majadahonda, Majadahonda (Madrid), Spain
,
Eduardo Martín-Sanz Servicio de Otorrinolaringología, Hospital Universitario Puerta de Hierro-Majadahonda, Majadahonda (Madrid), Spain
,
José Ángel González-García Servicio de Otorrinolaringología, Hospital Universitario Puerta de Hierro-Majadahonda, Majadahonda (Madrid), Spain
,
Jonathan Esteban-Sánchez Servicio de Otorrinolaringología y Unidad de Investigación, Hospital Universitario de Getafe, Getafe (Madrid), Spain
&
Rafael Ramírez-Camacho Servicio de Otorrinolaringología, Hospital Universitario Puerta de Hierro-Majadahonda, Majadahonda (Madrid), Spain
 show all
Pages 1101-1112 | Received 21 Jan 2010, Accepted 09 Feb 2010, Published online: 05 May 2010

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Ghassem Mohammadkhani & Elham Tavanai. (2021) The effect of the duration of treatment with antioxidants on age-related hearing loss. Hearing, Balance and Communication 19:3, pages 190-196.
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Ricardo Sanz-Fernández, Carolina Sánchez-Rodriguez, José Juan Granizo, Enrique Durio-Calero & Eduardo Martín-Sanz. (2015) Utility of auditory steady-state and brainstem responses in age-related hearing loss in rats. Acta Oto-Laryngologica 135:1, pages 35-41.
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Articles from other publishers (23)

Li Yan, Yan Huo, Jianrong Shi, Yang Dong & Hongsheng Tan. (2023) Traditional Chinese medicine for the prevention and treatment of presbycusis. Heliyon 9:12, pages e22422.
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Rosalía Fátima Heredia, Juan I. Riestra-Ayora, Joaquín Yanes-Díaz, Israel John Thuissard Vasallo, Cristina Andreu-Vázquez, Ricardo Sanz-Fernández & Carolina Sánchez-Rodríguez. (2023) Cocoa Polyphenols Prevent Age-Related Hearing Loss and Frailty in an In Vivo Model. Antioxidants 12:11, pages 1994.
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Ying Zhang, Hui Xie, Zhong-mei He, Feng Zhang, Ling-long Li, Na Wang & De-hong Mao. (2022) Medical Therapy of Hearing Impairment and Tinnitus with Chinese Medicine: An Overview. Chinese Journal of Integrative Medicine 29:8, pages 761-768.
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Jun Guo, Xiuqing Huang, Lin Dou, Mingjing Yan, Tao Shen, Weiqing Tang & Jian Li. (2022) Aging and aging-related diseases: from molecular mechanisms to interventions and treatments. Signal Transduction and Targeted Therapy 7:1.
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Konstantin Tziridis & Holger Schulze. (2022) Preventive Effects of Ginkgo-Extract EGb 761® on Noise Trauma-Induced Cochlear Synaptopathy. Nutrients 14:15, pages 3015.
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Xia Si, Zhiying Yu, Xiaolei Ren, Lin Huang & Yufei Feng. (2022) Efficacy and safety of standardized Ginkgo biloba L. leaves extract as an adjuvant therapy for sudden sensorineural hearing loss: A systematic review and meta-analysis. Journal of Ethnopharmacology 282, pages 114587.
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Stephan W. Barth, Martin D. Lehner, Gunnar P.H. Dietz & Holger Schulze. (2021) Pharmacologic treatments in preclinical tinnitus models with special focus on Ginkgo biloba leaf extract EGb 761®. Molecular and Cellular Neuroscience 116, pages 103669.
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Jing Wang & Jean-Luc Puel. (2020) Presbycusis: An Update on Cochlear Mechanisms and Therapies. Journal of Clinical Medicine 9:1, pages 218.
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Elham Tavanai, Ghassem Mohammadkhani, Saeid Farahani & Shohreh Jalaie. (2018) Protective Effects of Silymarin Against Age-Related Hearing Loss in an Aging Rat Model. Indian Journal of Otolaryngology and Head & Neck Surgery 71:S2, pages 1248-1257.
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Rodrigo Castañeda, Sathishkumar Natarajan, Seo Yule Jeong, Bin Na Hong & Tong Ho Kang. (2019) Traditional oriental medicine for sensorineural hearing loss: Can ethnopharmacology contribute to potential drug discovery?. Journal of Ethnopharmacology 231, pages 409-428.
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Jing Wang & Jean-Luc Puel. (2018) Toward Cochlear Therapies. Physiological Reviews 98:4, pages 2477-2522.
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Mun Young Chang, Jihye Rhee, Shin Hye Kim & Young Ho Kim. (2018) The Protective Effect of Egb 761 Against 3-Nitropropionic Acid-Induced Hearing Loss: The Role of Sirtuin 1. Clinical and Experimental Otorhinolaryngology 11:1, pages 9-16.
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Huan Wang, Xia Wu, Stephane Lezmi, Qian Li, William G. Helferich, Yueqing Xu & Hong Chen. (2017) Extract of Ginkgo biloba exacerbates liver metastasis in a mouse colon cancer Xenograft model. BMC Complementary and Alternative Medicine 17:1.
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Elham Tavanai & Ghassem Mohammadkhani. (2016) Role of antioxidants in prevention of age-related hearing loss: a review of literature. European Archives of Oto-Rhino-Laryngology 274:4, pages 1821-1834.
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Wei Zuo, Feng Yan, Bo Zhang, Jiantao Li & Dan Mei. (2017) Advances in the Studies of Ginkgo Biloba Leaves Extract on Aging-Related Diseases. Aging and disease 8:6, pages 812.
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Liting Hang, Adeline Henry Basil & Kah-Leong Lim. (2016) Nutraceuticals in Parkinson’s Disease. NeuroMolecular Medicine 18:3, pages 306-321.
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Ja-Won Koo, Mun Young Chang, Sung-Cheol Yun, Tae Su Kim, Soo-Keun Kong, Jong Woo Chung & Eui-Kyung Goh. (2015) The efficacy and safety of systemic injection of Ginkgo biloba extract, EGb761, in idiopathic sudden sensorineural hearing loss: a randomized placebo-controlled clinical trial. European Archives of Oto-Rhino-Laryngology 273:9, pages 2433-2441.
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Ricardo Sanz-Fernández, Carolina Sánchez-Rodriguez, José Juan Granizo, Enrique Durio-Calero & Eduardo Martín-Sanz. (2015) Accuracy of auditory steady state and auditory brainstem responses to detect the preventive effect of polyphenols on age-related hearing loss in Sprague–Dawley rats. European Archives of Oto-Rhino-Laryngology 273:2, pages 341-347.
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Yanyan Yin, Yuguo Ren, Wangyang Wu, Yuchan Wang, Mingcheng Cao, Zhengyi Zhu, Mingming Wang & Weizu Li. (2013) Protective effects of bilobalide on Aβ25–35 induced learning and memory impairments in male rats. Pharmacology Biochemistry and Behavior 106, pages 77-84.
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Norma Serrano-García, José Pedraza-Chaverri, José Juan Mares-Sámano, Marisol Orozco-Ibarra, Arturo Cruz-Salgado, Anabel Jiménez-Anguiano, Julio Sotelo & Cristina Trejo-Solís. (2013) Antiapoptotic Effects of EGb 761. Evidence-Based Complementary and Alternative Medicine 2013, pages 1-18.
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R. Arora, J. Sharma, W. Selvamurthy, A.R. Shivashankara, N. Mathew & M.S. Baliga. 2013. Bioactive Food as Dietary Interventions for the Aging Population. Bioactive Food as Dietary Interventions for the Aging Population 305 320 .
Patricia Rojas, Pedro Montes, Carolina Rojas, Norma Serrano-García & Julio César Rojas-Castañeda. (2012) Effect of a phytopharmaceutical medicine, Ginko biloba extract 761, in an animal model of Parkinson's disease: Therapeutic perspectives. Nutrition 28:11-12, pages 1081-1088.
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T. K. LimT. K. Lim. 2012. Edible Medicinal And Non Medicinal Plants. Edible Medicinal And Non Medicinal Plants 1 44 .

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