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International Journal of Neuroscience Volume 120, 2010 - Issue 11
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Research Article

Exposure to Nicotine Produces an Increase in Dopamine D2High Receptors: A Possible Mechanism for Dopamine Hypersensitivity

Gabriela Novak
,
Philip SeemanDepartment of Pharmacology, University of Toronto, Toronto, Ontario, Canada
&
Bernard Le FollCorrespondence[email protected]
Pages 691-697 | Received 01 Jan 2008, Published online: 13 Oct 2010

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Athanasios Gogos, Maria Skokou, Eleni Ferentinou & Philippos Gourzis. (2019) Nicotine consumption during the prodromal phase of schizophrenia – a review of the literature. Neuropsychiatric Disease and Treatment 15, pages 2943-2958.
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Articles from other publishers (30)

Guna Kanniah & Rishi Kumar. (2023) A selective literature review exploring the role of the nicotinic system in schizophrenia. General Psychiatry 36:2, pages e100756.
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Jasmina Mallet, Ophélia Godin, Yecodji Dansou, Nicolas Mazer, Claire Scognamiglio, Fabrice Berna, Laurent Boyer, Delphine Capdevielle, Isabelle Chéreau, Thierry D'Amato, Julien Dubreucq, Guillaume Fond, Sylvain Leigner, Pierre-Michel Llorca, David Misdrahi, Christine Passerieux, Romain Rey, Baptiste Pignon, Mathieu Urbach, Benoit Schorr, Franck Schürhoff, Le Strat Yann & Caroline Dubertret. (2022) Current (but not ex) cigarette smoking is associated with worse cognitive performances in schizophrenia: results from the FACE-SZ cohort. Psychological Medicine, pages 1-12.
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Frederike Schirmbeck, Els van der Ven, Lindy-Lou Boyette, Philip McGuire, Lucia R. Valmaggia, Matthew J. Kempton, Mark van der Gaag, Anita Riecher-Rössler, Neus Barrantes-Vidal, Barnaby Nelson, Marie-Odile Krebs, Stephan Ruhrmann, Gabriele Sachs, Bart P. F. Rutten, Merete Nordentoft, Lieuwe de Haan & Jentien M. Vermeulen. (2022) Differential trajectories of tobacco smoking in people at ultra-high risk for psychosis: Associations with clinical outcomes. Frontiers in Psychiatry 13.
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Guillaume Becker, Louis-Ferdinand Lespine, Mohamed Ali Bahri, Maria Elisa Serrano, Christian Lemaire, André Luxen, Ezio Tirelli & Alain Plenevaux. (2022) Exercise against cocaine sensitization in mice: a [18F]fallypride micro-PET study. Brain Communications 4:1.
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Sarah Davis & Jun Zhu. 2022. Behavioral Pharmacology of Drug Abuse: Current Status. Behavioral Pharmacology of Drug Abuse: Current Status 403 441 .
Mohamed A. Kandeil, Eman T. Mohammed, Rania A. Radi, Fatma Khalil, Abdel-Razik H. Abdel-Razik, Mohamed M. Abdel-Daim & Ghada M. Safwat. (2021) Nanonaringenin and Vitamin E Ameliorate Some Behavioral, Biochemical, and Brain Tissue Alterations Induced by Nicotine in Rats. Journal of Toxicology 2021, pages 1-15.
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Claudio Terravecchia, Giovanni Mostile, Cristina Rascunà, Gennarina Arabia, Paolo Barone, Roberto Marconi, Letterio Morgante, Andrea Quattrone, Alessandra Nicoletti & Mario Zappia. (2021) Does an association between cigarette smoking and Parkinson's Disease-related psychosis exist? Insights from a large non-demented cohort. Journal of the Neurological Sciences 427, pages 117509.
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Miranda L. Fisher, James R. Pauly, Brett Froeliger & Jill R. Turner. (2021) Translational Research in Nicotine Addiction. Cold Spring Harbor Perspectives in Medicine 11:6, pages a039776.
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Ruthie E. Wittenberg, Shannon L. Wolfman, Mariella De Biasi & John A. Dani. (2020) Nicotinic acetylcholine receptors and nicotine addiction: A brief introduction. Neuropharmacology 177, pages 108256.
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Rong Chen, Mark J. Ferris & Shiyu Wang. (2020) Dopamine D2 autoreceptor interactome: Targeting the receptor complex as a strategy for treatment of substance use disorder. Pharmacology & Therapeutics 213, pages 107583.
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Sun Mi Gu, Hye Jin Cha, So Woon Seo, Jin Tae Hong & Jaesuk Yun. (2019) Dopamine D1 receptor antagonist reduces stimulant-induced conditioned place preferences and dopamine receptor supersensitivity. Naunyn-Schmiedeberg's Archives of Pharmacology 393:1, pages 131-138.
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Gofarana Wilar, Yasuharu Shinoda, Toshikuni Sasaoka & Kohji Fukunaga. (2019) Crucial Role of Dopamine D2 Receptor Signaling in Nicotine-Induced Conditioned Place Preference. Molecular Neurobiology 56:12, pages 7911-7928.
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Christina L M Jobson, Justine Renard, Hanna Szkudlarek, Laura G Rosen, Brian Pereira, Daniel J Wright, Walter Rushlow & Steven R Laviolette. (2019) Adolescent Nicotine Exposure Induces Dysregulation of Mesocorticolimbic Activity States and Depressive and Anxiety-like Prefrontal Cortical Molecular Phenotypes Persisting into Adulthood. Cerebral Cortex 29:7, pages 3140-3153.
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Harriet Quigley & James H. MacCabe. (2019) The relationship between nicotine and psychosis. Therapeutic Advances in Psychopharmacology 9, pages 204512531985996.
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Camila Hirotsu, Matheus Negrao Pedroni, Laís Fernanda Berro, Sergio Tufik & Monica Levy Andersen. (2018) Nicotine and sleep deprivation: impact on pain sensitivity and immune modulation in rats. Scientific Reports 8:1.
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Herbert Mwebe. (2018) Serious mental illness and smoking cessation. British Journal of Mental Health Nursing 7:1, pages 39-46.
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Xiang Yang Zhang, Wen-Wang Rao, Qiong Yu, Yaqin Yu, Changgui Kou, Yun-Long Tan, Da-Chun Chen, Lingjun Zuo, Xiangguang Luo & Jair C. Soares. (2016) Association of the manganese superoxide dismutase gene Ala-9Val polymorphism with age of smoking initiation in male schizophrenia smokers. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 171:2, pages 243-249.
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Thakur Gurjeet Singh, Shiwali Sharma & Sonia Dhiman. 2016. Neuropathology of Drug Addictions and Substance Misuse. Neuropathology of Drug Addictions and Substance Misuse 201 208 .
Pedro Gurillo, Sameer Jauhar, Robin M Murray & James H MacCabe. (2015) Does tobacco use cause psychosis? Systematic review and meta-analysis. The Lancet Psychiatry 2:8, pages 718-725.
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Yan-You Huang, Amir Levine, Denise B. Kandel, Deqi Yin, Luca Colnaghi, Bettina Drisaldi & Eric R. Kandel. (2014) D1/D5 receptors and histone deacetylation mediate the Gateway Effect of LTP in hippocampal dentate gyrus. Learning & Memory 21:3, pages 153-160.
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Valentina Bashkatova, Sergey Sudakov, Galina Nazarova & Elena Alexeeva. (2014) The Action of Chronic Nicotine on the Effects of Ethanol on Anxiety, Locomotion and Metabolism and the Feeding and Drinking Behaviors of Rats. Pharmacology & Pharmacy 05:11, pages 1077-1084.
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Price E. Dickson, Mellessa M. Miller, Tiffany D. Rogers, Charles D. Blaha & Guy Mittleman. (2014) Effects of adolescent nicotine exposure and withdrawal on intravenous cocaine self-administration during adulthood in male C57BL/6J mice. Addiction Biology 19:1, pages 37-48.
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Jan-Peter van Wieringen, Jan Booij, Vladimir Shalgunov, Philip Elsinga & Martin C. Michel. (2012) Agonist high- and low-affinity states of dopamine D2 receptors: methods of detection and clinical implications. Naunyn-Schmiedeberg's Archives of Pharmacology 386:2, pages 135-154.
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James P. Burkett & Larry J. Young. (2012) The behavioral, anatomical and pharmacological parallels between social attachment, love and addiction. Psychopharmacology 224:1, pages 1-26.
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Xiang Yang Zhang, Da Chun Chen, Mei Hong Xiu, Li Hui, Haibo Liu, Xingguang Luo, Lingjun Zuo, Huiping Zhang, Therese A. Kosten & Thomas R. Kosten. (2012) Association of functional dopamine-beta-hydroxylase (DBH) 19bp insertion/deletion polymorphism with smoking severity in male schizophrenic smokers. Schizophrenia Research 141:1, pages 48-53.
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Xiomara A. Perez, Jason Ly, J. Michael McIntosh & Maryka Quik. (2012) Long-Term Nicotine Exposure Depresses Dopamine Release in Nonhuman Primate Nucleus Accumbens. Journal of Pharmacology and Experimental Therapeutics 342:2, pages 335-344.
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Michael Paolini & Mariella De Biasi. (2011) Mechanistic insights into nicotine withdrawal. Biochemical Pharmacology 82:8, pages 996-1007.
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Mariella De Biasi & John A. Dani. (2011) Reward, Addiction, Withdrawal to Nicotine. Annual Review of Neuroscience 34:1, pages 105-130.
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Cleo L. Crunelle, Sybille Schulz, Kora de Bruin, Michelle L. Miller, Wim van den Brink & Jan Booij. (2011) Dose-dependent and sustained effects of varenicline on dopamine D2/3 receptor availability in rats. European Neuropsychopharmacology 21:2, pages 205-210.
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Fang Zheng & Chang-Guo Zhan. (2011) Enzyme-therapy approaches for the treatment of drug overdose and addiction. Future Medicinal Chemistry 3:1, pages 9-13.
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