Citations (55)
Keep up to date with the latest research on this topic with citation updates for this article.
Read on this site (5)
Chun Dang, Yaoheng Lu, Qian Li, Chunyang Wang & Xiaofeng Ma. (2021) Efficacy of the sphingosine-1-phosphate receptor agonist fingolimod in animal models of stroke: an updated meta-analysis. International Journal of Neuroscience 131:1, pages 85-94.
Read now
Read now
Hongxing Zhou, Suyun Huang, Gavin Sunnassee, Weiyu Guo, Jian Chen, Yang Guo & Sheng Tan. (2017) Neuroprotective effects of adjunctive treatments for acute stroke thrombolysis: a review of clinical evidence. International Journal of Neuroscience 127:11, pages 1036-1046.
Read now
Read now
Alba Simats, Teresa García-Berrocoso & Joan Montaner. (2016) Natalizumab: a new therapy for acute ischemic stroke?. Expert Review of Neurotherapeutics 16:9, pages 1013-1021.
Read now
Read now
Pierre-Eric Juif, Stephan Kraehenbuehl & Jasper Dingemanse. (2016) Clinical pharmacology, efficacy, and safety aspects of sphingosine-1-phosphate receptor modulators. Expert Opinion on Drug Metabolism & Toxicology 12:8, pages 879-895.
Read now
Read now
Craig J Smith, Adam Denes, Pippa J Tyrrell & Mario Di Napoli. (2015) Phase II anti-inflammatory and immune-modulating drugs for acute ischaemic stroke. Expert Opinion on Investigational Drugs 24:5, pages 623-643.
Read now
Read now
Articles from other publishers (50)
Kyle Malone, Jennifer A. Shearer, Christian Waeber & Anne C. Moore. (2023) The impact of fingolimod on Treg function in brain ischaemia. European Journal of Immunology.
Crossref
Crossref
Igor A. Schepetkin, Galina A. Chernysheva, Oleg I. Aliev, Liliya N. Kirpotina, Vera I. Smol’yakova, Anton N. Osipenko, Mark B. Plotnikov, Anastasia R. Kovrizhina, Andrei I. Khlebnikov, Evgenii V. Plotnikov & Mark T. Quinn. (2022) Neuroprotective Effects of the Lithium Salt of a Novel JNK Inhibitor in an Animal Model of Cerebral Ischemia–Reperfusion. Biomedicines 10:9, pages 2119.
Crossref
Crossref
Andrea C. Diaz Diaz, Kyle Malone, Jennifer A. Shearer, Anne C. Moore & Christian Waeber. (2022) Preclinical Evaluation of Fingolimod in Rodent Models of Stroke With Age or Atherosclerosis as Comorbidities. Frontiers in Pharmacology 13.
Crossref
Crossref
Rosita Stanzione, Maurizio Forte, Maria Cotugno, Franca Bianchi, Simona Marchitti & Speranza Rubattu. (2020) Role of DAMPs and of Leukocytes Infiltration in Ischemic Stroke: Insights from Animal Models and Translation to the Human Disease. Cellular and Molecular Neurobiology 42:3, pages 545-556.
Crossref
Crossref
Kyle Malone, Andrea C. Diaz Diaz, Jennifer A. Shearer, Anne C. Moore & Christian Waeber. (2021) The effect of fingolimod on regulatory T cells in a mouse model of brain ischaemia. Journal of Neuroinflammation 18:1.
Crossref
Crossref
Amritha A. Candadai, Fang Liu, Arti Verma, Mir S. Adil, Moaddey Alfarhan, Susan C. Fagan, Payaningal R. Somanath & S. Priya Narayanan. (2021) Neuroprotective Effects of Fingolimod in a Cellular Model of Optic Neuritis. Cells 10:11, pages 2938.
Crossref
Crossref
Rafael Azevedo Dias, Leonor Dias, Elsa Azevedo & Pedro Castro. (2021) Acute Inflammation in Cerebrovascular Disease: A Critical Reappraisal with Focus on Human Studies. Life 11:10, pages 1103.
Crossref
Crossref
A. A. Kulesh. (2021) Neuroprotective therapy in acute ischemic stroke. Neurology, Neuropsychiatry, Psychosomatics 13:4, pages 94-102.
Crossref
Crossref
Andrea C. Diaz Diaz, Kyle Malone, Jennifer A. Shearer, Anne C. Moore & Christian Waeber. (2021) Histological, behavioural and flow cytometric datasets relating to acute ischaemic stroke in young, aged and ApoE−/− mice in the presence and absence of immunomodulation with fingolimod. Data in Brief 36, pages 107146.
Crossref
Crossref
Maryam Naseh, Jafar Vatanparast, Ali Rafati, Mahnaz Bayat & Masoud Haghani. (2021) The emerging role of FTY720 as a sphingosine 1‐phosphate analog for the treatment of ischemic stroke: The cellular and molecular mechanisms. Brain and Behavior 11:6.
Crossref
Crossref
Mark B. Plotnikov & Tatiana M. Plotnikova. (2021) Tyrosol as a Neuroprotector: Strong Effects of a “Weak” Antioxidant. Current Neuropharmacology 19:4, pages 434-448.
Crossref
Crossref
Xin Ying Chua, Leona T. Y. Ho, Ping Xiang, Wee Siong Chew, Brenda Wan Shing Lam, Christopher P. Chen, Wei-Yi Ong, Mitchell K. P. Lai & Deron R. Herr. (2020) Preclinical and Clinical Evidence for the Involvement of Sphingosine 1-Phosphate Signaling in the Pathophysiology of Vascular Cognitive Impairment. NeuroMolecular Medicine 23:1, pages 47-67.
Crossref
Crossref
Andrea C. Diaz Diaz, Jennifer A. Shearer, Kyle Malone & Christian Waeber. (2021) Acute Treatment With Fingolimod Does Not Confer Long-Term Benefit in a Mouse Model of Intracerebral Haemorrhage. Frontiers in Pharmacology 11.
Crossref
Crossref
Surojit Paul & Eduardo Candelario-Jalil. (2021) Emerging neuroprotective strategies for the treatment of ischemic stroke: An overview of clinical and preclinical studies. Experimental Neurology 335, pages 113518.
Crossref
Crossref
Damien Levard, Izaskun Buendia, Anastasia Lanquetin, Martina Glavan, Denis Vivien & Marina Rubio. (2021) Filling the gaps on stroke research: Focus on inflammation and immunity. Brain, Behavior, and Immunity 91, pages 649-667.
Crossref
Crossref
Kristy A. Zera & Marion S. Buckwalter. (2020) The Local and Peripheral Immune Responses to Stroke: Implications for Therapeutic Development. Neurotherapeutics 17:2, pages 414-435.
Crossref
Crossref
Ke Shang, Jia He, Jing Zou, Chuan Qin, Li Lin, Luo-Qi Zhou, Lin-Lin Yang, Long-Jun Wu, Wei Wang, Ke-Bin Zhan & Dai-Shi Tian. (2020) Fingolimod promotes angiogenesis and attenuates ischemic brain damage via modulating microglial polarization. Brain Research 1726, pages 146509.
Crossref
Crossref
Kota Kurisu, Jong Youl Kim, Jesung You & Midori A. Yenari. (2019) Therapeutic Hypothermia and Neuroprotection in Acute Neurological Disease. Current Medicinal Chemistry 26:29, pages 5430-5455.
Crossref
Crossref
Sara Grassi, Laura Mauri, Simona Prioni, Livia Cabitta, Sandro Sonnino, Alessandro Prinetti & Paola Giussani. (2019) Sphingosine 1-Phosphate Receptors and Metabolic Enzymes as Druggable Targets for Brain Diseases. Frontiers in Pharmacology 10.
Crossref
Crossref
Paulus Stefan Rommer & Johann Sellner. (2019) Repurposing multiple sclerosis drugs: a review of studies in neurological and psychiatric conditions. Drug Discovery Today 24:7, pages 1398-1404.
Crossref
Crossref
Kyle Malone, Sylvie Amu, Anne C. Moore & Christian Waeber. (2019) Immunomodulatory Therapeutic Strategies in Stroke. Frontiers in Pharmacology 10.
Crossref
Crossref
Angélica Salas-Perdomo, Francesc Miró-Mur, Mattia Gallizioli, Vanessa H. Brait, Carles Justicia, Anja Meissner, Xabier Urra, Angel Chamorro & Anna M. Planas. (2019) Role of the S1P pathway and inhibition by fingolimod in preventing hemorrhagic transformation after stroke. Scientific Reports 9:1.
Crossref
Crossref
Nguyen Hoang & Shahid M. Nimjee. 2019. Nervous System Drug Delivery. Nervous System Drug Delivery
473
500
.
Ciro De Luca, Anna Maria Colangelo, Lilia Alberghina & Michele Papa. (2018) Neuro-Immune Hemostasis: Homeostasis and Diseases in the Central Nervous System. Frontiers in Cellular Neuroscience 12.
Crossref
Crossref
Mei Li Ng, Nagendra S Yarla, Mario Menschikowski & Olga A Sukocheva. (2018) Regulatory role of sphingosine kinase and sphingosine-1-phosphate receptor signaling in progenitor/stem cells. World Journal of Stem Cells 10:9, pages 119-133.
Crossref
Crossref
Olivera Rajkovic, Geoffrey Potjewyd & Emmanuel Pinteaux. (2018) Regenerative Medicine Therapies for Targeting Neuroinflammation After Stroke. Frontiers in Neurology 9.
Crossref
Crossref
Andrea Huwiler & Uwe Zangemeister-Wittke. (2018) The sphingosine 1-phosphate receptor modulator fingolimod as a therapeutic agent: Recent findings and new perspectives. Pharmacology & Therapeutics 185, pages 34-49.
Crossref
Crossref
Qingmeng Chen & Min Lou. 2018. Cerebral Ischemic Reperfusion Injuries (CIRI). Cerebral Ischemic Reperfusion Injuries (CIRI)
43
56
.
Román Blanco, Gema Martínez-Navarrete, Francisco J. Valiente-Soriano, Marcelino Avilés-Trigueros, Consuelo Pérez-Rico, Ana Serrano-Puebla, Patricia Boya, Eduardo Fernández, Manuel Vidal-Sanz & Pedro de la Villa. (2017) The S1P1 receptor-selective agonist CYM-5442 protects retinal ganglion cells in endothelin-1 induced retinal ganglion cell loss. Experimental Eye Research 164, pages 37-45.
Crossref
Crossref
Naseer Ahmed, Daniele Linardi, Nazeer Muhammad, Cristiano Chiamulera, Guido Fumagalli, Livio San Biagio, Mebratu A. Gebrie, Muhammad Aslam, Giovanni Battista Luciani, Giuseppe Faggian & Alessio Rungatscher. (2017) Sphingosine 1-Phosphate Receptor Modulator Fingolimod (FTY720) Attenuates Myocardial Fibrosis in Post-heterotopic Heart Transplantation. Frontiers in Pharmacology 8.
Crossref
Crossref
Atsushi Mizuma & Midori A. Yenari. (2017) Anti-Inflammatory Targets for the Treatment of Reperfusion Injury in Stroke. Frontiers in Neurology 8.
Crossref
Crossref
De-Hyung Lee, Silvia Seubert, Konstantin Huhn, Lukas Brecht, Caroline Rötger, Anne Waschbisch, Johannes Schlachetzki, Alice Klausmeyer, Arthur Melms, Stefan Wiese, Jürgen Winkler & Ralf A. Linker. (2017) Fingolimod effects in neuroinflammation: Regulation of astroglial glutamate transporters?. PLOS ONE 12:3, pages e0171552.
Crossref
Crossref
William B. Rolland, Paul R. Krafft, Tim Lekic, Damon Klebe, Julia LeGrand, Abby Jones Weldon, Liang Xu & John H. Zhang. (2017) Fingolimod confers neuroprotection through activation of Rac1 after experimental germinal matrix hemorrhage in rat pups. Journal of Neurochemistry 140:5, pages 776-786.
Crossref
Crossref
Sinead O'Sullivan & Kumlesh K. Dev. (2017) Sphingosine-1-phosphate receptor therapies: Advances in clinical trials for CNS-related diseases. Neuropharmacology 113, pages 597-607.
Crossref
Crossref
Vanessa H. BraitGema TarrasónAmadeu GavaldàNúria GodessartAnna M. Planas. (2016) Selective Sphingosine 1-Phosphate Receptor 1 Agonist Is Protective Against Ischemia/Reperfusion in Mice. Stroke 47:12, pages 3053-3056.
Crossref
Crossref
Aldo Bonaventura, Luca Liberale, Alessandra Vecchié, Matteo Casula, Federico Carbone, Franco Dallegri & Fabrizio Montecucco. (2016) Update on Inflammatory Biomarkers and Treatments in Ischemic Stroke. International Journal of Molecular Sciences 17:12, pages 1967.
Crossref
Crossref
Francesc Miró-Mur, Xabier Urra, Mattia Gallizioli, Angel Chamorro & Anna M. Planas. (2016) Antigen Presentation After Stroke. Neurotherapeutics 13:4, pages 719-728.
Crossref
Crossref
Na Sun, Richard F. Keep, Ya Hua & Guohua Xi. (2016) Critical Role of the Sphingolipid Pathway in Stroke: a Review of Current Utility and Potential Therapeutic Targets. Translational Stroke Research 7:5, pages 420-438.
Crossref
Crossref
Mitchell K. P. Lai, Wee Siong Chew, Federico Torta, Angad Rao, Greg L. Harris, Jerold Chun & Deron R. Herr. (2016) Biological Effects of Naturally Occurring Sphingolipids, Uncommon Variants, and Their Analogs. NeuroMolecular Medicine 18:3, pages 396-414.
Crossref
Crossref
Ángel Chamorro, Ulrich Dirnagl, Xabier Urra & Anna M Planas. (2016) Neuroprotection in acute stroke: targeting excitotoxicity, oxidative and nitrosative stress, and inflammation. The Lancet Neurology 15:8, pages 869-881.
Crossref
Crossref
Maryam Nazari, Somaye Keshavarz, Ali Rafati, Mohammad Reza Namavar & Masoud Haghani. (2016) Fingolimod (FTY720) improves hippocampal synaptic plasticity and memory deficit in rats following focal cerebral ischemia. Brain Research Bulletin 124, pages 95-102.
Crossref
Crossref
Loredana La Mantia, Irene Tramacere, Belal Firwana, Ilaria Pacchetti, Roberto Palumbo & Graziella Filippini. (2016) Fingolimod for relapsing-remitting multiple sclerosis. Cochrane Database of Systematic Reviews 2016:4.
Crossref
Crossref
A Slowik, T Schmidt, C Beyer, S Amor, T Clarner & M Kipp. (2015) The sphingosine 1-phosphate receptor agonist FTY720 is neuroprotective after cuprizone-induced CNS demyelination. British Journal of Pharmacology 172:1, pages 80-92.
Crossref
Crossref
Olivier Meilhac. 2015. High Density Lipoproteins. High Density Lipoproteins
509
526
.
Rui Sheng, Tong-Tong Zhang, Valeria D. Felice, Tao Qin, Zheng-Hong Qin, Charles D. Smith, Ellen Sapp, Marian Difiglia & Christian Waeber. (2014) Preconditioning Stimuli Induce Autophagy via Sphingosine Kinase 2 in Mouse Cortical Neurons. Journal of Biological Chemistry 289:30, pages 20845-20857.
Crossref
Crossref
Lei Lu, Arnavaz Hajizadeh Barfejani, Tao Qin, Qiang Dong, Cenk Ayata & Christian Waeber. (2014) Fingolimod exerts neuroprotective effects in a mouse model of intracerebral hemorrhage. Brain Research 1555, pages 89-96.
Crossref
Crossref
Frederick R Walker, Kimberley A Jones, Madeleine J Patience, Zidan Zhao & Michael Nilsson. (2013) Stress as Necessary Component of Realistic Recovery in Animal Models of Experimental Stroke. Journal of Cerebral Blood Flow & Metabolism 34:2, pages 208-214.
Crossref
Crossref
Shunji Shiohira, Takumi Yoshida, Hidekazu Sugiura, Miki Nishida, Kosaku Nitta & Ken Tsuchiya. (2013) Sphingosine-1-phosphate acts as a key molecule in the direct mediation of renal fibrosis. Physiological Reports 1:7, pages e00172.
Crossref
Crossref
Aran Groves, Yasuyuki Kihara & Jerold Chun. (2013) Fingolimod: Direct CNS effects of sphingosine 1-phosphate (S1P) receptor modulation and implications in multiple sclerosis therapy. Journal of the Neurological Sciences 328:1-2, pages 9-18.
Crossref
Crossref
Takashi Shichita, Hiroaki Ooboshi, Takanari Kitazono & Akihiko Yoshimura. (2013) The role of innate immunity in post-ischemic inflammation. Nosotchu 35:2, pages 114-120.
Crossref
Crossref