1,488
Views
62
CrossRef citations to date
0
Altmetric
Research Article

Postoperative cognitive dysfunction, Alzheimer's disease, and anesthesia

, &
Pages 236-242 | Received 27 Jul 2013, Accepted 08 Aug 2013, Published online: 27 Sep 2013

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (1)

Federico Bilotta, Ega Qeva & Idit Matot. (2016) Anesthesia and cognitive disorders: a systematic review of the clinical evidence. Expert Review of Neurotherapeutics 16:11, pages 1311-1320.
Read now

Articles from other publishers (61)

Zhenhua YANG, Ailing WU & Maoxian ZHANG. (2023) Effects of dexmedetomidine on early cognitive function in elderly patients after abdominal surgery: a meta-analysis. Minerva Anestesiologica 89:11.
Crossref
Yongjie Bao, Wenni Rong, An Zhu, Yuan Chen, Huiyue Chen, Yirui Hong, Jingyang Le, Qiyao Wang, C. Benjamin Naman, Zhipeng Xu, Lin Liu, Wei Cui & Xiang Wu. (2023) Retinoic Acid Receptor Is a Novel Therapeutic Target for Postoperative Cognitive Dysfunction. Pharmaceutics 15:9, pages 2311.
Crossref
Huiwen Zheng, Qianmin Chen, Jingyue Zhang, Baiqing Ren, Tianya Liu, Chao Liu, Xiaoye Wang, Jingyi Sheng & Zhiping Wang. (2023) Postoperative serum CHI3L1 level is associated with postoperative cognitive dysfunction in elderly patients after hip fracture surgery: A prospective observational study. Heliyon 9:8, pages e18796.
Crossref
Keisuke Omiya, Yosuke Nakadate & Thomas Schricker. (2023) Intranasal insulin and cerebrospinal fluid glucose levels. Journal of Anesthesia.
Crossref
Hassan Abed. (2022) The effectiveness of intravenous sedation with midazolam for people with Alzheimer's disease requiring dental extraction. Oral Surgery 16:1, pages 133-138.
Crossref
Dai Shi, Jaime K. Y. Wong, Kaichuan Zhu, Peter G. Noakes & Gerhard Rammes. (2023) The Anaesthetics Isoflurane and Xenon Reverse the Synaptotoxic Effects of Aβ1–42 on Megf10-Dependent Astrocytic Synapse Elimination and Spine Density in Ex Vivo Hippocampal Brain Slices. International Journal of Molecular Sciences 24:2, pages 912.
Crossref
X. Li, J. X. Zhou, Y. D. Qu & X. Kuang. (2023) Сyclooxygenase-2 Inhibitor Parecoxib Reduces LPS-Induced Activation of BV2 Microglia Cells. Bulletin of Experimental Biology and Medicine 174:2, pages 210-215.
Crossref
Nikolaj Travica, Hajara Aslam, Adrienne O'Neil, Melissa M. Lane, Michael Berk, Elizabeth Gamage, Ken Walder, Zoe S.J. Liu, Toby Segasby & Wolfgang Marx. (2022) Brain derived neurotrophic factor in perioperative neurocognitive disorders: Current evidence and future directions. Neurobiology of Learning and Memory 193, pages 107656.
Crossref
Yi-Wei Wang, Liang Wang, Sheng-Jie Yuan, Yuan Zhang, Xin Zhang & Le-Ting Zhou. (2022) Postoperative Cognitive Dysfunction and Alzheimer’s Disease: A Transcriptome-Based Comparison of Animal Models. Frontiers in Aging Neuroscience 14.
Crossref
Pauline Glasman, Marion Houot, Raffaela Migliaccio, Stéphanie Bombois, Geoffroy Gagliardi, Federica Cacciamani, Marie Odile Habert, Bruno Dubois & Stéphane Epelbaum. (2022) Subtle postoperative cognitive disorder in preclinical Alzheimer's disease. Experimental Gerontology 161, pages 111715.
Crossref
Lidan Liu, Xin Zhang, Cong Wang, Xiuying Wu & Bo Long. (2022) Hypercholesterolemia aggravates sevoflurane‑induced cognitive impairment in aged rats by inducing neurological inflammation and apoptosis. Journal of Biochemical and Molecular Toxicology 36:5.
Crossref
Zhichao Wu, Han Wang, Zuan Shi & Yalan Li. (2022) Dexmedetomidine Mitigates Microglial Activation Associated with Postoperative Cognitive Dysfunction by Modulating the MicroRNA-103a-3p/VAMP1 Axis. Neural Plasticity 2022, pages 1-13.
Crossref
Hamieh Goshtasbi, Parvin Samadi Pakchin, Ali Movafeghi, Jaleh Barar, Ana M. Castejon, Hossein Omidian & Yadollah Omidi. (2022) Impacts of oxidants and antioxidants on the emergence and progression of Alzheimer's disease. Neurochemistry International 153, pages 105268.
Crossref
Manhua Zhu, Yong Qi, Huijuan He, Song Zhang & Yuliu Mei. (2021) Effect of quadratus lumborum block on postoperative cognitive function in elderly patients undergoing laparoscopic radical gastrectomy: a randomized controlled trial. BMC Geriatrics 21:1.
Crossref
Julie R. Mcswain, Joel M. Sirianni & Sylvia H. Wilson. (2021) Perioperative Considerations for Patients with a Known Diagnosis of Dementia. Advances in Anesthesia 39, pages 113-132.
Crossref
Zitan Zhang, Wei Li & Huiqun Jia. (2021) Postoperative Effects of Dexmedetomidine on Serum Inflammatory Factors and Cognitive Malfunctioning in Patients with General Anesthesia. Journal of Healthcare Engineering 2021, pages 1-6.
Crossref
Yunzhi Ling, Xiaohong Li, Li Yu, Yiyun Sun, Dongdong Yang & Zhiyi Li. (2021) Sevoflurane induces neuronal apoptosis via enhancing DNMT3L expression and promoting methylation of PSD95 promoter in postoperative cognitive dysfunction. Molecular & Cellular Toxicology 17:3, pages 287-295.
Crossref
Patricia Roque, Yosuke Nakadate, Hiroaki Sato, Tamaki Sato, Linda Wykes, Akiko Kawakami, Hiroshi Yokomichi, Takashi Matsukawa & Thomas Schricker. (2021) Intranasal administration of 40 and 80 units of insulin does not cause hypoglycemia during cardiac surgery: a randomized controlled trialL’administration intranasale de 40 et 80 unités d’insuline ne provoque pas d’hypoglycémie pendant une chirurgie cardiaque : une étude randomisée contrôlée. Canadian Journal of Anesthesia/Journal canadien d'anesthésie 68:7, pages 991-999.
Crossref
Lei Mao, Qingcui Zeng, Wenjie Su, Menglong Song, Jiacen Li & Min Xie. (2021) Elevation of miR-146a Inhibits BTG2/BAX Expression to Ameliorate Postoperative Cognitive Dysfunction Following Probiotics (VSL#3) Treatment. Molecular Neurobiology 58:7, pages 3457-3470.
Crossref
Meiyue Wang, Yong Zuo, Xincheng Li, Yan Li, Anand Thirupathi, Peng Yu, Guofen Gao, Changhao Zhou, Yanzhong Chang & Zhenhua Shi. (2021) Effect of sevoflurane on iron homeostasis and toxicity in the brain of mice. Brain Research 1757, pages 147328.
Crossref
Xiaoliang Wang, Lihai Chen, Yajie Xu, Wanling Wang, Youran Wang, Zhiyuan Zhang, Jing Zheng & Hongguang Bao. (2021) Gastrodin alleviates perioperative neurocognitive dysfunction of aged mice by suppressing neuroinflammation. European Journal of Pharmacology 892, pages 173734.
Crossref
Min Li, Tian-Long Wang & Dong-Xin Wang. (2021) An overview of Chinese multidisciplinary expert consensus on perioperative brain health in elderly patients. Chinese Medical Journal 134:1, pages 5-7.
Crossref
Peng-fei Liu, Teng Gao, Tian-zuo Li, Yi-tian Yang, Yong-xing Xu, Zhi-peng Xu & Wei-dong Mi. (2021) Repeated propofol exposure-induced neuronal damage and cognitive impairment in aged rats by activation of NF-κB pathway and NLRP3 inflammasome. Neuroscience Letters 740, pages 135461.
Crossref
Xu Lin, Jiaming Tang, Chen Liu, Xiaoxuan Li, Xipeng Cao, Bin Wang, Rui Dong, Wei Xu, Xinjuan Yu, Mingshan Wang & Yanlin Bi. (2020) Cerebrospinal fluid cholinergic biomarkers are associated with postoperative delirium in elderly patients undergoing Total hip/knee replacement: a prospective cohort study. BMC Anesthesiology 20:1.
Crossref
Je Jin Lee, Geun Joo Choi, Hyun Kang, Chong Wha Baek, Yong Hun Jung, Hwa Yong Shin, Yong Hee Park & Young Cheol Woo. (2020) Relationship between Surgery under General Anesthesia and the Development of Dementia: A Systematic Review and Meta-Analysis. BioMed Research International 2020, pages 1-22.
Crossref
Zhengxi Li, Meng Wei, Haiyan Lyu, Kang Huo, Liang Wang, Meng Zhang & Hua Su. (2019) Fracture shortly before stroke in mice leads to hippocampus inflammation and long-lasting memory dysfunction. Journal of Cerebral Blood Flow & Metabolism 40:2, pages 446-455.
Crossref
D. Astapenko, V. Zubáňová, M. Koščáková, M. Kuchařová, R. Hyšpler, A. Tichá, V. Černý, R. Štětina & Z. Zadák. (2020) Damage to lymfocyte DNA during anaesthesia: a pilot study comparing general and subarachnoid anaesthesia. Anesteziologie a intenzivní medicína 30:6, pages 302-310.
Crossref
Sabrina Bimonte, Antonio Barbieri, Nagoth Joseph Amruthraj, Marco Cascella, Arturo Cuomo & Claudio Arra. 2020. General Anesthesia Research. General Anesthesia Research 207 223 .
Monika Kucharova, David Astapenko, Veronika Zubanova, Maria Koscakova, Rudolf Stetina, Zdenek Zadak & Miloslav Hronek. (2019) Does Neuraxial Anesthesia as General Anesthesia Damage DNA? A Pilot Study in Patients Undergoing Orthopedic Traumatological Surgery. International Journal of Molecular Sciences 21:1, pages 84.
Crossref
Xing Ge, Ying Zhang, Yong Zuo, Muhammad Israr, Bowen Li, Peng Yu, Guofen Gao, Yan‐Zhong Chang & Zhenhua Shi. (2019) Transcriptomic analysis reveals the molecular mechanism of Alzheimer‐related neuropathology induced by sevoflurane in mice. Journal of Cellular Biochemistry 120:10, pages 17555-17565.
Crossref
Xi He, Ge Long, Chengxuan Quan, Bin Zhang, Jia Chen & Wen Ouyang. (2019) Insulin Resistance Predicts Postoperative Cognitive Dysfunction in Elderly Gastrointestinal Patients. Frontiers in Aging Neuroscience 11.
Crossref
Wen‐Jun Yan, Da‐Bin Wang, Dong‐Qing Ren, Ling‐Kai Wang, Zhong‐Yuan Hu, Ya‐Bing Ma, Jin‐Wen Huang & Shao‐Li Ding. (2019) AMPKα1 overexpression improves postoperative cognitive dysfunction in aged rats through AMPK‐Sirt1 and autophagy signaling. Journal of Cellular Biochemistry 120:7, pages 11633-11641.
Crossref
Katie J. Schenning & Kirk J. Hogan. 2019. The Perioperative Neurocognitive Disorders. The Perioperative Neurocognitive Disorders 48 60 .
Parveen Vitish-Sharma, Charles Maxwell-Armstrong, Boliang Guo, Crystal Yick & Austin G Acheson. (2019) The Trendelenburg Position and Cognitive Decline: A Case-Control Interventional Study Involving Healthy Volunteers. JMIR Perioperative Medicine 2:1, pages e11219.
Crossref
Suzan Uysal & David L. Reich. 2019. Handbook on the Neuropsychology of Aging and Dementia. Handbook on the Neuropsychology of Aging and Dementia 273 290 .
Adele Woodhouse, Carmen Maria Fernandez-Martos, Rachel Alice Kathryn Atkinson, Kelsey Anne Hanson, Jessica Marie Collins, Aidan Ryan O’Mara, Nico Terblanche, Marcus Welby Skinner, James Clement Vickers & Anna Elizabeth King. (2018) Repeat propofol anesthesia does not exacerbate plaque deposition or synapse loss in APP/PS1 Alzheimer’s disease mice. BMC Anesthesiology 18:1.
Crossref
Qi Zhang, Yanan Li, Yongjuan Bao, Chunping Yin, Xi Xin, Yangyang Guo, Fang Gao, Shuping Huo, Xiuli Wang & Qiujun Wang. (2018) Pretreatment with nimodipine reduces incidence of POCD by decreasing calcineurin mediated hippocampal neuroapoptosis in aged rats. BMC Anesthesiology 18:1.
Crossref
Ying Zhang, Yue-Xin Liu, Qiu-Xia Xiao, Qing Liu, Rui Deng, Jiang Bian, Isaac Bul Deng, Mohammed Al-Hawwas & Feng-Xu Yu. (2018) Microarray Expression Profiles of lncRNAs and mRNAs in Postoperative Cognitive Dysfunction. Frontiers in Neuroscience 12.
Crossref
Meng Wei, Haiyian Lyu, Kang Huo & Hua Su. (2018) Impact of Bone Fracture on Ischemic Stroke Recovery. International Journal of Molecular Sciences 19:5, pages 1533.
Crossref
Annie M. Racine, Tamara G. Fong, Yun Gou, Thomas G. Travison, Douglas Tommet, Kristen Erickson, Richard N. Jones, Bradford C. Dickerson, Eran Metzger, Edward R. Marcantonio, Eva M. Schmitt & Sharon K. Inouye. (2017) Clinical outcomes in older surgical patients with mild cognitive impairment. Alzheimer's & Dementia 14:5, pages 590-600.
Crossref
Wenyao Li, Qing Chai, Hongwei Zhang, Jing Ma, Chengfen Xu, Jifu Dong, Xianghua Wei, Zhiyi Wang & Kexian Zhang. (2018) High doses of minocycline may induce delayed activation of microglia in aged rats and thus cannot prevent postoperative cognitive dysfunction. Journal of International Medical Research 46:4, pages 1404-1413.
Crossref
Matthew Coghlan, Elizabeth Richards, Sadiq Shaik, Pablo Rossi, Ramesh Babu Vanama, Saumel Ahmadi, Christelle Petroz, Mark Crawford & Jason T. Maynes. (2018) Inhalational Anesthetics Induce Neuronal Protein Aggregation and Affect ER Trafficking. Scientific Reports 8:1.
Crossref
Chun-Long Zuo, Chun-Man Wang, Jin Liu, Ting Shen, Jiang-Ping Zhou, Xin-Rui Hao, Yi-Zhao Pan, Hua-Cheng Liu, Qing-Quan Lian & Han Lin. (2018) Isoflurane anesthesia in aged mice and effects of A1 adenosine receptors on cognitive impairment. CNS Neuroscience & Therapeutics 24:3, pages 212-221.
Crossref
Xiaoxia Duan, Tao Zhu, Chan Chen, Guanpeng Zhang, Junhui Zhang, Lin Wang, Luye Zhang, Maohua Wang & Xiaobin Wang. (2018) Serum glial cell line–derived neurotrophic factor levels and postoperative cognitive dysfunction after surgery for rheumatic heart disease. The Journal of Thoracic and Cardiovascular Surgery 155:3, pages 958-965.e1.
Crossref
Stephen Alcorn & Gemma Alcorn. 2018. Cognitive Changes after Surgery in Clinical Practice. Cognitive Changes after Surgery in Clinical Practice 17 32 .
Zhong-Hong Kong, Xin Chen, Hui-Po Hua, Liang Liang & Long-Juan Liu. (2017) The Oral Pretreatment of Glycyrrhizin Prevents Surgery-Induced Cognitive Impairment in Aged Mice by Reducing Neuroinflammation and Alzheimer’s-Related Pathology via HMGB1 Inhibition. Journal of Molecular Neuroscience 63:3-4, pages 385-395.
Crossref
Jae Hoon Lee, Eun Hee Kam, So Yeon Kim, So Yeong Cheon, Eun Jung Kim, Seungsoo Chung, Ji-Hyun Jeong & Bon-Nyeo Koo. (2017) Erythropoietin Attenuates Postoperative Cognitive Dysfunction by Shifting Macrophage Activation toward the M2 Phenotype. Frontiers in Pharmacology 8.
Crossref
Yongbo Ding, Cunxian Shi, Linjing Chen, Piliang Ma, Kezhong Li, Jin Jin, Qingfeng Zhang & Aizhi Li. (2017) Effects of andrographolide on postoperative cognitive dysfunction and the association with NF‑κB/MAPK pathway. Oncology Letters.
Crossref
Qi Zhang, Ya-Nan Li, Yang-Yang Guo, Chun-Ping Yin, Fang Gao, Xi Xin, Shu-Ping Huo, Xiu-Li Wang & Qiu-Jun Wang. (2017) Effects of preconditioning of electro-acupuncture on postoperative cognitive dysfunction in elderly. Medicine 96:26, pages e7375.
Crossref
Elisabeth Colon, Edward A. Bittner, Barry Kussman, Mary Ellen McCann, Sulpicio Soriano & David Borsook. (2017) Anesthesia, brain changes, and behavior: Insights from neural systems biology. Progress in Neurobiology 153, pages 121-160.
Crossref
Giuseppe P. Cortese & Corinna Burger. (2017) Neuroinflammatory challenges compromise neuronal function in the aging brain: Postoperative cognitive delirium and Alzheimer’s disease. Behavioural Brain Research 322, pages 269-279.
Crossref
Q Zhang, Li Y-N, Guo Y-Y, Yin C-P, F Gao, X Xin, Huo S-P, Wang X-L, Wang Q-J, P. Bosch & M. van den Noort. (2017) Effects of preconditioning of electro-acupuncture on postoperative cognitive dysfunction in elderly: A prospective, randomized, controlled trial. Deutsche Zeitschrift für Akupunktur 60:4, pages 36-37.
Crossref
Rongqiao HeRongqiao He. 2017. Formaldehyde and Cognition. Formaldehyde and Cognition 143 166 .
Elizabeth M. Gabrielli & Roderic G. Eckenhoff. 2017. Brain and Spine Surgery in the Elderly. Brain and Spine Surgery in the Elderly 65 80 .
Yun-zhi Ling, Xiao-hong Li, Li Yu, Ye Zhang, Qi-sheng Liang, Xiao-di Yang & Hong-tao Wang. (2016) Protective effects of parecoxib on rat primary astrocytes from oxidative stress induced by hydrogen peroxide帕瑞昔布对过氧化氢诱导的原代星形胶质细胞 氧化应激的保护作用. Journal of Zhejiang University-SCIENCE B 17:9, pages 692-702.
Crossref
Chaoshuang WuRuichun WangXiaoyu LiJunping Chen. (2016) Preoperative Serum MicroRNA-155 Expression Independently Predicts Postoperative Cognitive Dysfunction After Laparoscopic Surgery for Colon Cancer. Medical Science Monitor 22, pages 4503-4508.
Crossref
Paul S. García, Elizabeth W. Duggan, Ian L. McCullough, Simon C. Lee & David Fishman. (2015) Postanesthesia Care for the Elderly Patient. Clinical Therapeutics 37:12, pages 2651-2665.
Crossref
Xiya Yu, Shupeng Liu, Jinbao Li, Xiaohua Fan, Yuanjie Chen, Xiaoying Bi, Shanrong Liu & Xiaoming Deng. (2015) MicroRNA-572 Improves Early Post-Operative Cognitive Dysfunction by Down-Regulating Neural Cell Adhesion Molecule 1. PLOS ONE 10:2, pages e0118511.
Crossref
Bin Zhu. (2014) Leptin: New hope for the treatment of post-operative cognitive dysfunction?. Medical Science Monitor 20, pages 866-868.
Crossref
Angela G. Catic & Sheila Barnett. (2014) Perioperative Education in Geriatrics. International Anesthesiology Clinics 52:4, pages 1-13.
Crossref
Jeffrey H. Silverstein. (2014) Cognition, Anesthesia, and Surgery. International Anesthesiology Clinics 52:4, pages 42-57.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.