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International Journal of Neuroscience Volume 50, 1990 - Issue 3-4
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Original Article

Misincorporation of Uracil Into DNA as Possible Contributor to Neuronal aging and Abiotrophy

Paolo Mazzarello Clinica Neurologica I, Universitci di Milano, Italy
,
Federico Focher Istituto di Genetica Biochimica ed Evoluzionistica, CNR, Pavia, Italy
,
Annalisa Verri Istituto di Genetica Biochimica ed Evoluzionistica, CNR, Pavia, Italy
&
Silvio Spadari Istituto di Genetica Biochimica ed Evoluzionistica, CNR, Pavia, Italy
Pages 169-174 | Received 21 Sep 1989, Published online: 07 Jul 2009

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Gilberto Levy, Bruce Levin & Eliasz Engelhardt. (2022) Echoes of William Gowers’s concept of abiotrophy. Journal of the History of the Neurosciences 31:4, pages 425-449.
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Articles from other publishers (11)

Ilya Velegzhaninov, Vera Mezenceva, Olga Shostal, Ancha Baranova & Alexey Moskalev. (2015) Age dynamics of DNA damage and CpG methylation in the peripheral blood leukocytes of mice. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 775, pages 38-42.
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Umakanta Swain & Kalluri Subba Rao. (2012) Age-dependent decline of DNA base excision repair activity in rat cortical neurons. Mechanisms of Ageing and Development 133:4, pages 186-194.
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Damien Brégeon, Zara A Doddridge, Ho Jin You, Bernard Weiss & Paul W Doetsch. (2003) Transcriptional Mutagenesis Induced by Uracil and 8-Oxoguanine in Escherichia coli. Molecular Cell 12:4, pages 959-970.
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Daniel K. Rogstad, Pingfang Liu, Artur Burdzy, Susan S. Lin & Lawrence C. Sowers. (2002) Endogenous DNA Lesions Can Inhibit the Binding of the AP-1 (c-Jun) Transcription Factor. Biochemistry 41:25, pages 8093-8102.
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Benjamin C. BlountMatthew M. MackCarol M. WehrJames T. MacGregorRobert A. HiattGene WangSunitha N. WickramasingheRichard B. EversonBruce N. Ames. (1997) Folate deficiency causes uracil misincorporation into human DNA and chromosome breakage: Implications for cancer and neuronal damage. Proceedings of the National Academy of Sciences 94:7, pages 3290-3295.
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M N PrichardG M DukeE S Mocarski. (1996) Human cytomegalovirus uracil DNA glycosylase is required for the normal temporal regulation of both DNA synthesis and viral replication. Journal of Virology 70:5, pages 3018-3025.
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Federico Focher, Annalisa Verri, Simona Verzeletti, Paolo Mazzarello & Silvio Spadari. (1992) Uracil in Oris of herpes simplex 1 alters its specific recognition by origin binding protein (OBP): does virus induced uracil-DNA glycosylase play a key role in viral reactivation and replication?. Chromosoma 102:S1, pages S67-S71.
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P. MAZZARELLO, A. VERRI, C. MONDELLO, S. COLOMBO, G. MAGA, S. SPADARI & F. FOCHER. (1992) Enzymes of DNA Metabolism in a Patient with the Wiedemann-Rautenstrauch Progeroid Syndrome. Annals of the New York Academy of Sciences 663:1 Aging and Cel, pages 440-441.
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Paolo Mazzarello, Marco Poloni, Silvio Spadari & Federico Focher. (1992) DNA repair mechanisms in neurological diseases: facts and hypotheses. Journal of the Neurological Sciences 112:1-2, pages 4-14.
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Umberto Laforenza, Cesare Patrini, Marco Poloni, Paolo Mazzarello, Mauro Ceroni, D. Carleton Gajdusek & Ralph M. Garruto. (1992) Thiamin mono- and pyrophosphatase activities from brain homogenate of Guamanian amyotrophic lateral sclerosis and parkinsonism-dementia patients. Journal of the Neurological Sciences 109:2, pages 156-161.
Crossref
F. Focher, P. Mazzarello, A. Verri, G. Biamonti & S. Spadari. 1992. Biology of Aging. Biology of Aging 8 16 .

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