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Scandinavian Journal of Clinical and Laboratory Investigation Volume 74, 2014 - Issue 5
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Research Article

Cord blood procalcitonin and Interleukin-6 are highly sensitive and specific in the prediction of early-onset sepsis in preterm infants

Eva SteinbergerResearch Unit for Neonatal Infectious Diseases and Epidemiology, Division of Neonatology, Department of Paediatrics, Medical University of Graz, Austria
,
Nora HoferResearch Unit for Neonatal Infectious Diseases and Epidemiology, Division of Neonatology, Department of Paediatrics, Medical University of Graz, Austria
&
Bernhard ReschResearch Unit for Neonatal Infectious Diseases and Epidemiology, Division of Neonatology, Department of Paediatrics, Medical University of Graz, AustriaCorrespondenceBernhard.resch@medunígraz.at
Pages 432-436 | Received 06 Nov 2013, Accepted 01 Mar 2014, Published online: 16 Apr 2014

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Chinedu U. Ebenebe, Franziska Hesse, Martin E. Blohm, Roman Jung, Steffen Kunzmann & Dominique Singer. (2021) Diagnostic accuracy of interleukin-6 for early-onset sepsis in preterm neonates. The Journal of Maternal-Fetal & Neonatal Medicine 34:2, pages 253-258.
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Bernhard Resch, Eva Steinberger & Nora Hofer. (2015) Reply to Kartal & Kartal. Early preterm sepsis: too complex to solve. Scandinavian Journal of Clinical and Laboratory Investigation 75:3, pages 283-283.
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Articles from other publishers (22)

Anna Baštan, Jan Hálek, Tomáš Fürst & Vladimír Mihál. (2023) Diagnostic significance of postnatal interleukin-6 dynamics in preterm neonates. Pediatrie pro praxi 24:6, pages 398-402.
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Giovanni Boscarino, Rossana Migliorino, Giulia Carbone, Giusy Davino, Valentina Giovanna Dell’Orto, Serafina Perrone, Nicola Principi & Susanna Esposito. (2023) Biomarkers of Neonatal Sepsis: Where We Are and Where We Are Going. Antibiotics 12:8, pages 1233.
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Julia Eichberger & Bernhard Resch. (2022) Reliability of Interleukin-6 Alone and in Combination for Diagnosis of Early Onset Neonatal Sepsis: Systematic Review. Frontiers in Pediatrics 10.
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Julia Eichberger, Elisabeth Resch & Bernhard Resch. (2022) Diagnosis of Neonatal Sepsis: The Role of Inflammatory Markers. Frontiers in Pediatrics 10.
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Nagwa Mohamed Sabry Mahmoud, Mohammed Abdelhakeem, Hadir Haroun Ahmed Mohamed & Gamal Baheeg. (2022) Validity of Platelet to Lymphocyte Ratio and Neutrophil to Lymphocyte Ratio in Diagnosing Early-onset Neonatal Sepsis in Full-term Newborns. Journal of Comprehensive Pediatrics 13:1.
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O. R. E. Dongen, L. M. van Leeuwen, P. K. de Groot, K. Vollebregt, I. Schiering, B. A. Wevers, S. M. Euser & M. A. van Houten. (2021) Umbilical Cord Procalcitonin to Detect Early-Onset Sepsis in Newborns: A Promising Biomarker. Frontiers in Pediatrics 9.
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Glenn Malin Froeschle, Tanja Bedke, Michael Boettcher, Samuel Huber, Dominique Singer & Chinedu Ulrich Ebenebe. (2020) T cell cytokines in the diagnostic of early-onset sepsis. Pediatric Research 90:1, pages 191-196.
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Mandy Busse, Anke Redlich, Roland Hartig, Serban-Dan Costa, Henning Rathert, Stefan Fest & Ana Claudia Zenclussen. (2021) Imbalance between inflammatory and regulatory cord blood B cells following pre-term birth. Journal of Reproductive Immunology 145, pages 103319.
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Blandine Bianco, Bérengère François-Garret, Marine Butin, Cyril Dalmasso, Florence Casagrande, Mostafa Mokhtari & Sergio Eleni Dit Trolli. (2021) Procalcitonin in Preterm Neonates: A Different Threshold and Prolonged Interpretation. Frontiers in Pediatrics 9.
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Xia-Fang Chen, Jing Wu, Yi-Dan Zhang, Chen-Xing Zhang, Xu-Ting Chen, Wei Zhao & Tong-Xin Chen. (2021) Role of SOCS3 in enhanced acute-phase protein genes by neonatal macrophages in response to IL-6. Journal of Microbiology, Immunology and Infection 54:2, pages 206-212.
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I-Lun Chen, Hsin-Chun Huang, Mei-Chen Ou-Yang, Feng-Shun Chen, Mei-Yung Chung & Chih-Cheng Chen. (2020) A novel method to detect bacterial infection in premature infants: Using a combination of inflammatory markers in blood and saliva. Journal of Microbiology, Immunology and Infection 53:6, pages 892-899.
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Jan Halek, Martin Novak, Anna Medkova, Tomas Furst & Jarmila Juranova. (2018) The role of nCD64 in the diagnosis of neonatal sepsis in preterm newborns. Biomedical Papers 162:4, pages 284-288.
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Qi Cheng, Lili Tang & Yibiao Wang. (2018) Regulatory role of miRNA‑26a in neonatal sepsis. Experimental and Therapeutic Medicine.
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Xia-Fang Chen, Jing Wu, Yi-Dan Zhang, Chen-Xing Zhang, Xu-Ting Chen, Jian-Hua Sun & Tong-Xin Chen. (2018) Role of Zc3h12a in enhanced IL-6 production by newborn mononuclear cells in response to lipopolysaccharide. Pediatrics & Neonatology 59:3, pages 288-295.
Crossref
Chun-Chih Peng, Jui-Hsing Chang, Hsiang-Yu Lin, Po-Jen Cheng & Bai-Horng Su. (2018) Intrauterine inflammation, infection, or both (Triple I): A new concept for chorioamnionitis. Pediatrics & Neonatology 59:3, pages 231-237.
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Olivia Oria de Rueda Salguero, José Beceiro Mosquera, Marta Barrionuevo González, María Jesús Ripalda Crespo & Cristina Olivas López de Soria. (2017) Procalcitonina en sangre de cordón en la valoración del riesgo de sepsis neonatal precoz. Anales de Pediatría 87:2, pages 87-94.
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Olivia Oria de Rueda Salguero, José Beceiro Mosquera, Marta Barrionuevo González, María Jesús Ripalda Crespo & Cristina Olivas López de Soria. (2017) Cord blood procalcitonin in the assessment of early-onset neonatal sepsis. Anales de Pediatría (English Edition) 87:2, pages 87-94.
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Rosemary D. Higgins, George Saade, Richard A. Polin, William A. Grobman, Irina A. Buhimschi, Kristi Watterberg, Robert M. Silver & Tonse N.K. Raju. (2016) Evaluation and Management of Women and Newborns With a Maternal Diagnosis of Chorioamnionitis. Obstetrics & Gynecology 127:3, pages 426-436.
Crossref
Shin Ae YoonJi Young ChunYo Han HoJi Sook KimHye Soo YooSe In SungSo Yoon AhnYun Sil ChangWon Soon Park. (2016) Clinical Characteristics of Early Onset Sepsis in Micropreemie Born at 25 or Less than 25 Weeks of Gestational Age. Korean Journal of Perinatology 27:1, pages 53.
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Claudio Chiesa, Lucia Pacifico, Fabio Natale, Nora Hofer, John F. Osborn & Bernhard Resch. (2015) Fetal and early neonatal interleukin-6 response. Cytokine 76:1, pages 1-12.
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Su Lin, Zhongtao Huang, Mingfang Wang, Zhiyuan Weng, Dawu Zeng, Yanliang Zhang, Yueyong Zhu & Jiaji Jiang. (2015) Interleukin-6 as an early diagnostic marker for bacterial sepsis in patients with liver cirrhosis. Journal of Critical Care 30:4, pages 732-738.
Crossref
Claudio Chiesa, Lucia Pacifico, John F. Osborn, Enea Bonci, Nora Hofer & Bernhard Resch. (2015) Early-Onset Neonatal Sepsis. Medicine 94:30, pages e1230.
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