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Original Article

The Effect of pH on Bilirubin Binding by Human Erythrocytes

Pages 453-459 | Received 02 Dec 1971, Accepted 25 Jan 1972, Published online: 13 May 2010

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D. Brites, R. Silva & A. Brito. (1997) Effect of bilirubin on erythrocyte shape and haemolysis, under hypotonic, aggregating or non-aggregating conditions, and correlation with cell age. Scandinavian Journal of Clinical and Laboratory Investigation 57:4, pages 337-349.
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Rolf Brodersen & Leo Stern. (1980) Binding of Bilirubin to Albumin. CRC Critical Reviews in Clinical Laboratory Sciences 11:4, pages 307-399.
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D. Bratlid. (1972) The Effect of Antimicrobial Agents on Bilirubin Binding by Human Erythrocytes. Scandinavian Journal of Clinical and Laboratory Investigation 30:3, pages 331-337.
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D. Bratlid. (1972) The Effect of Free Fatty Acids, Bile Acids, and Hematin on Bilirubin Binding by Human Erythrocytes. Scandinavian Journal of Clinical and Laboratory Investigation 30:1, pages 107-112.
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Articles from other publishers (33)

Isha Khurana, Prince Allawadhi, Amit Khurana, Amit Kumar Srivastava, Umashanker Navik, Anil Kumar Banothu & Kala Kumar Bharani. (2021) Can bilirubin nanomedicine become a hope for the management of COVID-19?. Medical Hypotheses 149, pages 110534.
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Thor W. R. Hansen, Ronald J. Wong & David K. Stevenson. (2020) Molecular Physiology and Pathophysiology of Bilirubin Handling by the Blood, Liver, Intestine, and Brain in the Newborn. Physiological Reviews 100:3, pages 1291-1346.
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Domenico Lapenna, Giuliano Ciofani, Sante Donato Pierdomenico, Maria Adele Giamberardino, Sante Ucchino & Giovanni Davì. (2017) Association of serum bilirubin with oxidant damage of human atherosclerotic plaques and the severity of atherosclerosis. Clinical and Experimental Medicine 18:1, pages 119-124.
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Karri Barabas, Rowan Milner, James Farese, Chris Baylis, Byron Croker, Linda Archer & Christopher Adin. (2008) Hyperbilirubinemia's protective effect against cisplatin nephrotoxicity in the Gunn rat. Anti-Cancer Drugs 19:5, pages 495-502.
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Antony F. McDonagh. (2007) Bilirubin Toxicity to Human Erythrocytes: A More Sanguine View. Pediatrics 120:1, pages 175-178.
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Kristin Kirkby, Chris Baylis, Anupam Agarwal, Byron Croker, Linda Archer & Christopher Adin. (2007) Intravenous bilirubin provides incomplete protection against renal ischemia-reperfusion injury in vivo. American Journal of Physiology-Renal Physiology 292:2, pages F888-F894.
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Maria Alexandra Brito, Rui F.M. Silva & Dora Brites. (2006) Bilirubin toxicity to human erythrocytes: A review. Clinica Chimica Acta 374:1-2, pages 46-56.
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Kristin A. Kirkby & Christopher A. Adin. (2006) Products of heme oxygenase and their potential therapeutic applications. American Journal of Physiology-Renal Physiology 290:3, pages F563-F571.
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Thor Willy Ruud Hansen. (2002) Mechanisms of bilirubin toxicity: clinical implications. Clinics in Perinatology 29:4, pages 765-778.
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Maria Alexandra Brito, Carlos D. Brondino, José J.G. Moura & Dora Brites. (2001) Effects of Bilirubin Molecular Species on Membrane Dynamic Properties of Human Erythrocyte Membranes: A Spin Label Electron Paramagnetic Resonance Spectroscopy Study. Archives of Biochemistry and Biophysics 387:1, pages 57-65.
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H. Rashid, Mohammad K. Ali & S Tayyab. (2000) Effect of pH and temperature on the binding of bilirubin to human erythrocyte membranes. Journal of Biosciences 25:2, pages 157-161.
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Brito, Silva, Tiribelli & Brites. (2000) Assessment of bilirubin toxicity to erythrocytes. Implication in neonatal jaundice management. European Journal of Clinical Investigation 30:3, pages 239-247.
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Saad Tayyab & Mohammad K. Ali. (1997) Binding of Bilirubin to Mammalian Erythrocytes. Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology 118:1, pages 97-103.
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S. Tayyab & M.K. Ali. (1995) Binding of bilirubin to erythrocytes from different mammalian species. Comparative Biochemistry and Physiology Part A: Physiology 111:3, pages 507-509.
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Yair Amit, Shirley Fedunec, Panakkezhum D. Thomas, Mark J. Poznansky & David Schiff. (1990) Bilirubin-neural cell interaction: Characterization of initial cell surface binding leading to toxicity in the neuroblastoma cell line N-115. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1055:1, pages 36-42.
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Dag Bratlid. (1990) How Bilirubin Gets into the Brain. Clinics in Perinatology 17:2, pages 449-465.
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Philip Roth & Richard A. Polin. (1988) Controversial Topics in Kernicterus. Clinics in Perinatology 15:4, pages 965-990.
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G. K. MALIK, G. K. GOEL, P. N. VISHWANATHAN, P. K. MISRA & B. SHARMA. (1986) Free and Erythrocyte-Bound Bilirubin in Neonatal Jaundice. Acta Paediatrica 75:4, pages 545-549.
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T. W. R. HANSEN & D. BRATLID. (1986) Bilirubin and Brain Toxicity. Acta Paediatrica 75:4, pages 513-522.
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Gerard B. Odell & Henry S. Schutta. 1985. Cerebral Energy Metabolism and Metabolic Encephalopathy. Cerebral Energy Metabolism and Metabolic Encephalopathy 229 261 .
F. EBBESEN. (2008) EFFECT OF EXCHANGE TRANSFUSION ON SERUM RESERVE ALBUMIN FOR BINDING OF BILIRUBIN AND INDEX OF SERUM BILIRUBIN TOXICITY. Acta Paediatrica 70:5, pages 643-648.
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Richard B. Krakaur & John W. Scanlon. (1981) Detection of Free Bilirubin and Estimation of Reserve Albumin Binding Capacity. Clinics in Laboratory Medicine 1:2, pages 329-343.
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Inés Ana Gioia, Raquel E. Serrani & J. L. Corchs. (1981) Bilirubin Adsorption In Vitro by Foetal and Adult Human Erythrocytes. Clinical Chemistry and Laboratory Medicine 19:6.
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Rita G. Harper, Concepcion G. Sia & Catherine M.P. Kierney. (1980) Kernicterus 1980: Problems and Practices Viewed from the Perspective of the Practicing Clinician. Clinics in Perinatology 7:1, pages 75-92.
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Leonore Ballowitz. (1980) Bilirubin encephalopathy: Changing concepts. Brain and Development 2:3, pages 219-227.
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Richard P. Wennberg, Charles E. Ahlfors & L.Fraser Rasmussen. (1979) The pathochemistry of kernicterus. Early Human Development 3:4, pages 353-372.
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ANTONY F. McDONAGH. 1979. The Porphyrins. The Porphyrins 293 491 .
L.H.Th.S. Kortbeek & A.C. Booij. (1979) Bilirubin excess, erythrophages and siderophages in differentiation of blood in cerebrospinal fluid. Clinical Neurology and Neurosurgery 81:4, pages 265-279.
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R. BRODERSEN. (2008) PREVENTION OF KERNICTERUS, BASED ON RECENT PROGRESS IN BILIRUBIN CHEMISTRY. Acta Paediatrica 66:5, pages 625-634.
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Kwang-sun Lee, Lawrence M. Gartner, Arthur I. Eidelman & Sudhakar Ezhuthachan. (1977) Unconjugated Hyperbilirubinemia in Very Low Birth Weight Infants. Clinics in Perinatology 4:2, pages 305-320.
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Michael W. Simon, Janice M. Rusnak & Antony J. Mukkada. (1976) Toxicity of bilirubin to Leishmania tropica promastigotes. Experimental Parasitology 39:1, pages 51-58.
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M. Pays & M. Beljean. (1975) Microdetermination of unbound bilirubin in sera. Application to the prevention of kernicterus by estimating the bilirubin-binding capacity of serum albumin. Clinica Chimica Acta 59:2, pages 121-128.
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DAG BRATLID & ASBJØSRN LANGSLET. (2008) DISPLACEMENT OF ALBUMIN‐BOUND BILIRUBIN BY INJECTABLE DIAZEPAM PREPARATIONS IN VITRO. Acta Paediatrica 62:5, pages 510-512.
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