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Original Article

Production, characterization and use of monoclonal antibodies against the major extracellular human cysteine proteinase inhibitors cystatin C and kininogen

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Pages 573-582 | Received 21 Dec 1987, Accepted 07 Mar 1988, Published online: 08 Jul 2009

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Gustav Östner, Veronica Lindström, Alexander B. Postnikov, Tatiana I. Solovyeva, Össur I. Emilsson & Anders Grubb. (2011) High throughput testing of drug library substances and monoclonal antibodies for capacity to reduce formation of cystatin C dimers to identify candidates for treatment of hereditary cystatin C amyloid angiopathy. Scandinavian Journal of Clinical and Laboratory Investigation 71:8, pages 676-682.
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Maria Bjarnadottir, Carol Nilsson, Veronica Lindstrom, Ann Westman, Pia Davidsson, Finnbogi Thormodsson, Hannes Blondal, Gunnar Gudmundsson & Anders Grubb. (2001) The cerebral hemorrhage-producing cystatin C variant (L68Q) in extracellular fluids. Amyloid 8:1, pages 1-10.
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Eirikur Benedikz, George S. Merz, Valerie Schwenk, Teit E. Johansen, Henryk M. Wisniewski & Julie I. Rushbrook. (1999) Cellular processing of the amyloidogenic cystatin C variant of hereditary cerebral hemorrhage with amyloidosis, Icelandic type. Amyloid 6:3, pages 172-182.
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E. Randers, H. Kristensen, E.J Erlandsen & S Danielsen. (1998) Serum cystatin C as a marker of the renal function. Scandinavian Journal of Clinical and Laboratory Investigation 58:7, pages 585-592.
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Valur Emilsson, Leifur Thorsteinsson, Olafur Jensson & Gunnar Gudnnundsson. (1996) Human cystatin C expression and regulation by TGF-β1: Implications for the pathogenesis of hereditary cystatin C amyloid angiopathy causing brain hemorrhage. Amyloid 3:2, pages 110-118.
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M. Bjarnadóttir, A. Grubb & Í. Ólafsson. (1995) Promoter-mediated, dexamethasone-induced increase in cystatin C production by HeLa cells. Scandinavian Journal of Clinical and Laboratory Investigation 55:7, pages 617-623.
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Allain Collé, Catherine Tavera, Danielle Prévot, Jeanne Leung-Tack, Yolène Thomas, Yves Manuel, Jacques Benveniste & Jacques Leibowitch. (1992) Cystatin C Levels in Sera of Patients with Human Immunodeficiency Virus Infection. A New Avidin-Biotin ELISA Assay for Its Measurement. Journal of Immunoassay 13:1, pages 47-60.
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Allain Collé, Catherine Tavera, Patricia Laurent, Jeanne Leung-tack & Jean Pierre Girolami. (1990) Direct Radioimmunoassay of Rat Cystatin C: Increased Urinary Excretion of This Cysteine Proteases Inhibitor During Chromate Nephropathy. Journal of Immunoassay 11:2, pages 199-214.
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Articles from other publishers (49)

Samar Hunaiti, Hanna Wallin, Mia Eriksson, Marcus Järås & Magnus Abrahamson. (2020) Secreted cystatins decrease proliferation and enhance apoptosis of human leukemic cells. FEBS Open Bio 10:10, pages 2166-2181.
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M. Rafalik, M. Spodzieja, A.S. Kołodziejczyk, S. Rodziewicz-Motowidło, A. Szymańska, A. Grubb & P. Czaplewska. (2019) The identification of discontinuous epitope in the human cystatin C – Monoclonal antibody HCC3 complex. Journal of Proteomics 191, pages 58-67.
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Izabela Behrendt, Martyna Prądzińska, Marta Spodzieja, Paulina Czaplewska, Aleksandra S. Kołodziejczyk, Aneta Szymańska, Franciszek Kasprzykowski, Susanna L. Lundström, Roman A. Zubarev & Sylwia Rodziewicz-Motowidło. (2018) Identification and characterization of antibodies elicited by human cystatin C fragment. Journal of Molecular Recognition 31:4, pages e2689.
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Hanna Wallin, Jenny Apelqvist, Freddi Andersson, Ulf Ekström & Magnus Abrahamson. (2017) Low-level internalization of cystatin E/M affects legumain activity and migration of melanoma cells. Journal of Biological Chemistry 292:35, pages 14413-14424.
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Izabela Behrendt, Martyna Prądzińska, Marta Spodzieja, Aleksandra S. Kołodziejczyk, Sylwia Rodziewicz-Motowidło, Aneta Szymańska & Paulina Czaplewska. (2016) Epitope location for two monoclonal antibodies against human cystatin C, representing opposite aggregation inhibitory properties. Amino Acids 48:7, pages 1717-1729.
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Sandra Whelly, Gaiane Serobian, Clinton Borchardt, Jonathan Powell, Seethal Johnson, Katarina Hakansson, Veronica Lindstrom, Magnus Abrahamson, Anders Grubb & Gail A. Cornwall. (2014) Fertility Defects in Mice Expressing the L68Q Variant of Human Cystatin C. Journal of Biological Chemistry 289:11, pages 7718-7729.
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Gustav Östner, Veronica Lindström, Per Hjort Christensen, Maciej Kozak, Magnus Abrahamson & Anders Grubb. (2013) Stabilization, Characterization, and Selective Removal of Cystatin C Amyloid Oligomers. Journal of Biological Chemistry 288:23, pages 16438-16450.
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Hanna Wallin, Magnus Abrahamson & Ulf Ekström. (2013) Cystatin C Properties Crucial for Uptake and Inhibition of Intracellular Target Enzymes. Journal of Biological Chemistry 288:23, pages 17019-17029.
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Noora Ristiniemi, Qiu-Ping Qin, Veronica Lindström, Anders Grubb & Kim Pettersson. (2012) Quantification of cystatin C by time-resolved fluorometry-based immunoassays. Journal of Immunological Methods 378:1-2, pages 56-61.
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Anna Śladewska, Aneta Szymańska, Marlena Kordalska, Agnieszka Lewandowska, Aleksandra S. Kołodziejczyk, Gabriela Paraschiv, Michael Przybylski & Paulina Czaplewska. (2011) Identification of the epitope for anti-cystatin C antibody. Journal of Molecular Recognition 24:4, pages 687-699.
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Jon J Briggs, Mads H Haugen, Harald T Johansen, Adam I Riker, Magnus Abrahamson, Øystein Fodstad, Gunhild M Mælandsmo & Rigmor Solberg. (2010) Cystatin E/M suppresses legumain activity and invasion of human melanoma. BMC Cancer 10:1.
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Hanna Wallin, Maria Bjarnadottir, Lotte K. Vogel, Johan Wassélius, Ulf Ekström & Magnus Abrahamson. (2010) Cystatins – Extra- and intracellular cysteine protease inhibitors: High-level secretion and uptake of cystatin C in human neuroblastoma cells. Biochimie 92:11, pages 1625-1634.
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Noora Ristiniemi, Qiu-Ping Qin, Alexander Postnikov, Anders Grubb & Kim Pettersson. (2010) Dry-Reagent Double-Monoclonal Assay for Cystatin C. Clinical Chemistry 56:9, pages 1424-1431.
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Ulf Ekström, Hanna Wallin, Julia Lorenzo, Bo Holmqvist, Magnus Abrahamson & Francesc X. Avilés. (2008) Internalization of cystatin C in human cell lines. The FEBS Journal 275:18, pages 4571-4582.
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Bjarne Vincents, Reine Vindebro, Magnus Abrahamson & Ulrich von Pawel-Rammingen. (2008) The Human Protease Inhibitor Cystatin C Is an Activating Cofactor for the Streptococcal Cysteine Protease IdeS. Chemistry & Biology 15:9, pages 960-968.
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Taichi Ito, Akiyo Komiya‐Ito, Tomohiko Arataki, Yoshitaka Furuya, Yasutomo Yajima, Satoru Yamada, Katsuji Okuda & Tetsuo Kato. (2008) Relationship Between Antimicrobial Protein Levels in Whole Saliva and Periodontitis. Journal of Periodontology 79:2, pages 316-322.
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THOMAS JIBORN, MAGNUS ABRAHAMSON, VIRGIL GADALEANU, AKE LUNDWALL & ANDERS BJARTELL. (2006) Aberrant expression of cystatin C in prostate cancer is associated with neuroendocrine differentiation. BJU International 98:1, pages 189-196.
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Johan Wassélius, Kjell Johansson, Katarina Håkansson, Magnus Abrahamson & Berndt Ehinger. (2004) Cystatin C uptake in the eye. Graefe's Archive for Clinical and Experimental Ophthalmology 243:6, pages 583-592.
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Thomas Jiborn, Magnus Abrahamson, Hanna Wallin, Johan Malm, Åke Lundwall, Virgil Gadaleanu, Per-Anders Abrahamsson & Anders Bjartell. (2004) Cystatin C Is Highly Expressed in the Human Male Reproductive System. Journal of Andrology 25:4, pages 564-572.
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Maria Nilsson, Xin Wang, Sylwia Rodziewicz-Motowidlo, Robert Janowski, Veronica Lindström, Patrik Önnerfjord, Gunilla Westermark, Zbigniew Grzonka, Mariusz Jaskolski & Anders Grubb. (2004) Prevention of Domain Swapping Inhibits Dimerization and Amyloid Fibril Formation of Cystatin C. Journal of Biological Chemistry 279:23, pages 24236-24245.
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Davis Massey. (2004) Commentary: Clinical diagnostic use of cystatin C. Journal of Clinical Laboratory Analysis 18:1, pages 55-60.
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B. Werle, K. Sauckel, C.-M. Nathanson, M. Bjarnadottir, E. Spiess, W. Ebert & M. Abrahamson. (2003) Cystatins C, E/M and F in Human Pleural Fluids of Patients with Neoplastic and Inflammatory Lung Disorders. Biological Chemistry 384:2.
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Carl‐Michael Nathanson, Johan Wassélius, Hanna Wallin & Magnus Abrahamson. (2002) Regulated expression and intracellular localization of cystatin F in human U937 cells. European Journal of Biochemistry 269:22, pages 5502-5511.
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T Yamaza, Y Tsuji, T Goto, M.A Kido, K Nishijima, R Moroi, A Akamine & T Tanaka. (2001) Comparison in localization between cystatin C and cathepsin K in osteoclasts and other cells in mouse tibia epiphysis by immunolight and immunoelectron microscopy. Bone 29:1, pages 42-53.
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Sogu� Coulibaly, Herwig Schwihla, Magnus Abrahamson, Adriana Albini, Christa Cerni, Jason L. Clark, Ken M. Ng, Nobuhiko Katunuma, Otto Schlappack, Josef Gl�ssl & Lukas Mach. (1999) Modulation of invasive properties of murine squamous carcinoma cells by heterologous expression of cathepsin B and cystatin C. International Journal of Cancer 83:4, pages 526-531.
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