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Scandinavian Journal of Clinical and Laboratory Investigation Volume 52, 1992 - Issue 7

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Original Article

Pancreatic beta-cell function evaluated by intravenous glucose and glucagon stimulation. A comparison between insulin and C-peptide to measure insulin secretion

A. Gottsäter Department of Medicine, University of Lund, Malmö General Hospital, Malmö, Sweden

M. Landin-Olsson Department of Medicine, University of Lund, Malmö General Hospital, Malmö, Sweden

P. Fernlund Clinical Chemistry University of Lund, Malmö General Hospital, Malmö, Sweden

B. Gullberg Epidemiology and Health Care Research, University of Lund, Malmö General Hospital, Malmö, Sweden

Å. Lernmark Department of Medicine, University of Lund, Malmö General Hospital, Malmö, Sweden; Department of Medicine, University of Washington, Seattle, WAUSA

G. Sundkvist Department of Medicine, University of Lund, Malmö General Hospital, Malmö, Sweden

Pages 631-639 | Received 30 Dec 1991, Accepted 18 Mar 1992, Published online: 08 Jul 2009

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https://doi.org/10.3109/00365519209115506

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Xia Li, Jin Cheng & Zhiguang Zhou. (2016) Revisiting multiple models of progression of β-cell loss of function in type 1 diabetes: Significance for prevention and cure. Journal of Diabetes 8:4, pages 460-469.
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Jong-Dai Kim, Sung Ju KangMin Kyung LeeSe Eun ParkEun Jung RheeCheol-Young ParkKi-Won OhSung-Woo ParkWon-Young Lee. (2016) C-Peptide-Based Index Is More Related to Incident Type 2 Diabetes in Non-Diabetic Subjects than Insulin-Based Index. Endocrinology and Metabolism 31:2, pages 320.
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M. K. Svensson, M. Tyrberg, L. Nyström, H. J. Arnqvist, J. Bolinder, J. Östman, S. Gudbjörnsdottir, M. Landin-Olsson & J. W. Eriksson. (2015) The risk for diabetic nephropathy is low in young adults in a 17-year follow-up from the Diabetes Incidence Study in Sweden (DISS). Older age and higher BMI at diabetes onset can be important risk factors. Diabetes/Metabolism Research and Reviews 31:2, pages 138-146.
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E. WILDOVÁ, P. DLOUHÝ, P. KRAML, J. RAMBOUSKOVÁ, V. ŠMEJKALOVÁ, J. POTOČKOVÁ & M. ANDĚL. (2013) Orally Administered Whey Proteins Have Comparable Effect on C-Peptide Secretion in Healthy Subjects as Standard C-Peptide Stimulation Tests. Physiological Research, pages 179-186.
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E. Ekholm, A. Gottsäter, L. B. Dahlin & G. Sundkvist. (2011) No signs of progressive beta cell damage during 20 years of prospective follow-up of autoantibody-negative diabetes. Acta Diabetologica 49:1, pages 57-62.
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Hye-Jin YoonYoun-Zoo ChoJi-young KimByung-Joon KimKeun-Young ParkGwan-Pyo KohDae-Ho LeeDong-Mee Lim. (2012) Correlations between Glucagon Stimulated C-peptide Levels and Microvascular Complications in Type 2 Diabetes Patients. Diabetes & Metabolism Journal 36:5, pages 379.
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Iain S. Begg, Garth L. Warnock & David M. Thompson. 2012. Visual Dysfunction in Diabetes. Visual Dysfunction in Diabetes 339 365 .

E. Vandemeulebroucke, B. Keymeulen, K. Decochez, I. Weets, C. De Block, F. Féry, U. Van de Velde, I. Vermeulen, P. De Pauw, C. Mathieu, D. G. Pipeleers & F. K. Gorus. (2009) Hyperglycaemic clamp test for diabetes risk assessment in IA-2-antibody-positive relatives of type 1 diabetic patients. Diabetologia 53:1, pages 36-44.
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Melanie Rodacki, Adolpho Milech & José Egídio Paulo de Oliveira. (2008) A secreção residual do peptídeo C faz diferença no tratamento do diabetes melito tipo 1?. Arquivos Brasileiros de Endocrinologia & Metabologia 52:2, pages 322-333.
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Ingrid L Mostad, Kristian S Bjerve, Marit R Bjorgaas, Stian Lydersen & Valdemar Grill. (2006) Effects of n−3 fatty acids in subjects with type 2 diabetes: reduction of insulin sensitivity and time-dependent alteration from carbohydrate to fat oxidation. The American Journal of Clinical Nutrition 84:3, pages 540-550.
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B. Berger, H. Borg, P. Fernlund, G. Stenström & G. Sundkvist. (2006) Islet antibodies associated with pancreatic B-cell dysfunction at and 3�years after diagnosis of diabetes in subjects aged 35?64�years old: degree of impairment less severe than in those aged 0?34�years old. Diabetic Medicine 23:11, pages 1180-1185.
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E. Bakhtadze, H. Borg, G. Stenström, P. Fernlund, H. J. Arnqvist, A. Ekbom-Schnell, J. Bolinder, J. W. Eriksson, S. Gudbjörnsdottir, L. Nyström, L. C. Groop & G. Sundkvist. (2006) HLA-DQB1 genotypes, islet antibodies and beta cell function in the classification of recent-onset diabetes among young adults in the nationwide Diabetes Incidence Study in Sweden. Diabetologia 49:8, pages 1785-1794.
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Gunnar Stenström, Anders Gottsäter, Ekaterine Bakhtadze, Bo Berger & Göran Sundkvist. (2005) Latent Autoimmune Diabetes in Adults. Diabetes 54:suppl_2, pages S68-S72.
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Nicole A. Sherry, Emily B. Tsai & Kevan C. Herold. (2005) Natural History of β-Cell Function in Type 1 Diabetes. Diabetes 54:suppl_2, pages S32-S39.
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Anna Schölin, Agneta Siegbahn, Lars Lind, Christian Berne, Göran Sundkvist, Elisabeth Björk & F. Anders Karlsson. (2004) CRP and IL‐6 concentrations are associated with poor glycemic control despite preserved β‐cell function during the first year after diagnosis of type 1 diabetes. Diabetes/Metabolism Research and Reviews 20:3, pages 205-210.
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A. Scholin, L. Bjorklund, H. Borg, H. Arnqvist, E. Bjork, G. Blohme, J. Bolinder, J. W. Eriksson, S. Gudbjornsdottir, L. Nystrom, J. Ostman, A. F. Karlsson & G. Sundkvist. (2004) Islet antibodies and remaining beta-cell function 8 years after diagnosis of diabetes in young adults: a prospective follow-up of the nationwide Diabetes Incidence Study in Sweden. Journal of Internal Medicine 255:3, pages 384-391.
Crossref

Maria Svensson, Göran Sundkvist, Hans J. Arnqvist, Elisabeth Björk, Göran Blohmé, Jan Bolinder, Marianne Henricsson, Lennarth Nyström, Ole Torffvit, Ingeborg Waernbaum, Jan Östman & Jan W. Eriksson. (2003) Signs of Nephropathy May Occur Early in Young Adults With Diabetes Despite Modern Diabetes Management. Diabetes Care 26:10, pages 2903-2909.
Crossref

Michael Alvarsson, Göran Sundkvist, Ibe Lager, Marianne Henricsson, Kerstin Berntorp, Eva Fernqvist-Forbes, Lars Steen, Gunilla Westermark, Per Westermark, Thomas Örn & Valdemar Grill. (2003) Beneficial Effects of Insulin Versus Sulphonylurea on Insulin Secretion and Metabolic Control in Recently Diagnosed Type 2 Diabetic Patients. Diabetes Care 26:8, pages 2231-2237.
Crossref

Marianne Henricsson, Lennarth Nyström, Göran Blohmé, Jan Östman, Carin Kullberg, Maria Svensson, Anna Schölin, Hans J. Arnqvist, Elisabeth Björk, Jan Bolinder, Jan W. Eriksson & Göran Sundkvist. (2003) The Incidence of Retinopathy 10 Years After Diagnosis in Young Adult People With Diabetes. Diabetes Care 26:2, pages 349-354.
Crossref

H. Borg, C. Marcus, S. Sjöblad, P. Fernlund & G. Sundkvist. (2002) Insulin autoantibodies are of less value compared with islet antibodies in the clinical diagnosis of autoimmune type 1 diabetes in children older than 3 yr of age. Pediatric Diabetes 3:3, pages 149-154.
Crossref

Henrik Borg, Anders Gottsäter, Per Fernlund & Göran Sundkvist. (2002) A 12-Year Prospective Study of the Relationship Between Islet Antibodies and β-Cell Function At and After the Diagnosis in Patients With Adult-Onset Diabetes. Diabetes 51:6, pages 1754-1762.
Crossref

Marianne Henricsson, Kerstin Berntorp, Per Fernlund & Göran Sundkvist. (2002) Progression of Retinopathy in Insulin-Treated Type 2 Diabetic Patients. Diabetes Care 25:2, pages 381-385.
Crossref

A. J. Scheen. 1996. Glucagon III. Glucagon III 211 222 .

A. Gottsäter, M. Landin-Olsson, Å. Lernmark, P. Fernlund, G. Sundkvist & W.A. Hagopian. (1995) Glutamate decarboxylase antibody levels predict rate of β-cell decline in adult-onset diabetes. Diabetes Research and Clinical Practice 27:2, pages 133-140.
Crossref

A. Gotts�ter, M. Landin-Olsson, �. Lernmark, P. Fernlund & G. Sundkvist. (1994) Islet cell antibodies are associated with?-cell failure also in obese adult onset diabetic patients. Acta Diabetologica 31:4, pages 226-231.
Crossref

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Pancreatic beta-cell function evaluated by intravenous glucose and glucagon stimulation. A comparison between insulin and C-peptide to measure insulin secretion

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Pancreatic beta-cell function evaluated by intravenous glucose and glucagon stimulation. A comparison between insulin and C-peptide to measure insulin secretion

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