Rapid virological response in peripheral blood mononuclear cells with an increase of hepatitis C virus-specific interferon-gamma production predisposes to sustained virological response in patients with chronic hepatitis C genotype 1 undergoing treatment with pegylated-interferon alpha 2a plus ribavirin

A. Perrella Department of Infectious Disease and ImmunologyCorrespondence[email protected]

C. Sbreglia Department of Infectious Disease and Immunology

L. Atripaldi Department of Infectious Disease and Immunology

C. Esposito Laboratory of Virology, Hospital D. Cotugno, Naples, Italy

A. D'Antonio Department of Infectious Disease and Immunology

O. Perrella Department of Infectious Disease and Immunology

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Sasmita Mishra, Bianca J. Lavelle, Joe Desrosiers, Matt T. Ardito, Frances Terry, William D. Martin, Anne S. De Groot & Stephen H. Gregory. (2014) Dendritic Cell-Mediated, DNA-Based Vaccination against Hepatitis C Induces the Multi-Epitope-Specific Response of Humanized, HLA Transgenic Mice. PLoS ONE 9:8, pages e104606.
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Nicola Coppola, Stefania De Pascalis, Mariantonietta Pisaturo, Laurenza Paradiso, Margherita Macera, Nicolina Capoluongo, Loredana Alessio, Maria Stanzione, Caterina Sagnelli, Carmine Minichini & Evangelista Sagnelli. (2013) Sustained virological response to antiviral treatment in chronic hepatitis C patients may be predictable by HCV-RNA clearance in peripheral blood mononuclear cells. Journal of Clinical Virology 58:4, pages 748-750.
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J. Angulo, K. Pino, C. Pavez, F. Biel, P. Labbé, J. F. Miquel, A. Soza & M. López‐Lastra. (2013) Genetic variations in host IL 28 B links to the detection of peripheral blood mononuclear cells–associated hepatitis C virus RNA in chronically infected patients . Journal of Viral Hepatitis 20:4, pages 263-272.
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Aarthi Chary, Mark A. Winters, Robert Eisen, Thomas H. Knight, David M. Asmuth & Mark Holodniy. (2012) Quantitation of hepatitis C virus RNA in peripheral blood mononuclear cells in HCV‐monoinfection and HIV/HCV‐coinfection. Journal of Medical Virology 84:3, pages 431-437.
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Antonio Mollo, Antonella Stile, Carlo Alviggi, Marcello Granata, Giuseppe De Placido, Alessandro Perrella, Anna d’Antonio & Ettore Cicinelli. (2011) Endometrial polyps in infertile patients: do high concentrations of interferon-gamma play a role?. Fertility and Sterility 96:5, pages 1209-1212.
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