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Liver and Biliary Disease

Symptoms in patients with ulcerative colitis in remission are associated with visceral hypersensitivity and mast cell activity

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Pages 981-987 | Received 13 Jan 2011, Accepted 22 Mar 2011, Published online: 30 May 2011

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Yan Chen, Jiafei Cheng, Yiling Zhang, Jiande D Z Chen & Florin M Seralu. (2021) Electroacupuncture at ST36 Relieves Visceral Hypersensitivity via the NGF/TrkA/TRPV1 Peripheral Afferent Pathway in a Rodent Model of Post-Inflammation Rectal Hypersensitivity. Journal of Inflammation Research 14, pages 325-339.
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David J Gracie & Alexander C Ford. (2015) IBS-like symptoms in patients with ulcerative colitis. Clinical and Experimental Gastroenterology 8, pages 101-109.
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Peter LM Jansen. (2011) This month in Scandinavian Journal of Gastroenterology. Scandinavian Journal of Gastroenterology 46:7-8, pages 771-772.
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Brigida Barberio, David J Gracie, Christopher J Black & Alexander C Ford. (2023) Impact of Baseline Disease Activity and Trial Duration on Efficacy of Biologics in Active Crohn’s Disease: Meta-analysis. Inflammatory Bowel Diseases.
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Jay Pravda. (2022) Evidence-based pathogenesis and treatment of ulcerative colitis: A causal role for colonic epithelial hydrogen peroxide. World Journal of Gastroenterology 28:31, pages 4263-4298.
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Haiyang Wang, Xiaojing Zhao, Xiufang Cui, Meifeng Wang, Chunhua Jiao, Jiajia Li, Yan Yang, Yi Li & Hongjie Zhang. (2021) A Pilot Study of Clinical Evaluation and Formation Mechanism of Irritable Bowel Syndrome-like Symptoms in Inflammatory Bowel Disease Patients in Remission. Journal of Neurogastroenterology and Motility 27:4, pages 612-625.
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Hanna Tufvesson, Julia Dreja, Olle Ekberg, Peter Leander, Sven Månsson & Bodil Ohlsson. (2020) Quantified small bowel motility in patients with ulcerative colitis and gastrointestinal symptoms: a pilot study. Acta Radiologica 62:7, pages 858-866.
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Yan Chen, Yu Guo, Payam Gharibani, Jie Chen, Florin M. Selaru & Jiande D. Z. Chen. (2021) Transitional changes in gastrointestinal transit and rectal sensitivity from active to recovery of inflammation in a rodent model of colitis. Scientific Reports 11:1.
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Georgios Mavroudis, Hans Strid, Börje Jonefjäll & Magnus Simrén. (2020) Visceral hypersensitivity is together with psychological distress and female gender associated with severity of IBS‐like symptoms in quiescent ulcerative colitis. Neurogastroenterology & Motility 33:3.
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A. A. SheptulinK. E. Vinogradskaya. (2019) Inflammatory Bowel Diseases and Irritable Bowel Syndrome: Overlap of Two Nosological Forms or Two Variants of the Same Disease?. Russian Journal of Gastroenterology, Hepatology, Coloproctology 29:5, pages 43-48.
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Yoshiharu Uno. (2019) Hypothesis: Mechanism of irritable bowel syndrome in inflammatory bowel disease. Medical Hypotheses 132, pages 109324.
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David J Gracie, P John Hamlin & Alexander C Ford. (2019) The influence of the brain–gut axis in inflammatory bowel disease and possible implications for treatment. The Lancet Gastroenterology & Hepatology 4:8, pages 632-642.
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Kata Csekő, Bram Beckers, Daniel Keszthelyi & Zsuzsanna Helyes. (2019) Role of TRPV1 and TRPA1 Ion Channels in Inflammatory Bowel Diseases: Potential Therapeutic Targets?. Pharmaceuticals 12:2, pages 48.
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David J Gracie, Christopher J M Williams, Ruchit Sood, Saqib Mumtaz, Hassan M Bholah, John P Hamlin & Alexander C Ford. (2016) Poor Correlation Between Clinical Disease Activity and Mucosal Inflammation, and the Role of Psychological Comorbidity, in Inflammatory Bowel Disease. American Journal of Gastroenterology 111:4, pages 541-551.
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A. Deiteren, J. G. De Man, C. Keating, W. Jiang, H. U. De Schepper, P. A. Pelckmans, S. M. Francque & B. Y. De Winter. (2015) Mechanisms contributing to visceral hypersensitivity: focus on splanchnic afferent nerve signaling. Neurogastroenterology & Motility 27:12, pages 1709-1720.
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B. Jharap, W. J. Sandborn, W. Reinisch, G. D'Haens, A. M. Robinson, W. Wang, B. Huang, A. Lazar, R. B. Thakkar & J.-F. Colombel. (2015) Randomised clinical study: discrepancies between patient-reported outcomes and endoscopic appearance in moderate to severe ulcerative colitis. Alimentary Pharmacology & Therapeutics 42:9, pages 1082-1092.
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Bastian Schirmer, Thomas Rezniczek, Roland Seifert & Detlef Neumann. (2015) Proinflammatory role of the histamine H4 receptor in dextrane sodium sulfate-induced acute colitis. Biochemical Pharmacology 98:1, pages 102-109.
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Sushil K. Sarna & John H. Winston. (2015) Symptom Generation by Mucosal Inflammation in Irritable Bowel Syndrome. Gastroenterology 149:2, pages 287-289.
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C. Brochard, L. Siproudhis, A. Ropert, A. Mallak, J-F Bretagne & G. Bouguen. (2015) Anorectal dysfunction in patients with ulcerative colitis: impaired adaptation or enhanced perception?. Neurogastroenterology & Motility 27:7, pages 1032-1037.
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Harissios Vliagoftis & A.D. Befus. 2015. Mucosal Immunology. Mucosal Immunology 859 882 .
Matthew J. Hamilton, Sandra M. Frei & Richard L. Stevens. (2014) The Multifaceted Mast Cell in Inflammatory Bowel Disease. Inflammatory Bowel Diseases 20:12, pages 2364-2378.
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Detlef Neumann & Roland Seifert. (2014) The therapeutic potential of histamine receptor ligands in inflammatory bowel disease. Biochemical Pharmacology 91:1, pages 12-17.
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Giovanni Barbara, Cesare Cremon & Vincenzo Stanghellini. (2014) Inflammatory bowel disease and irritable bowel syndrome. Current Opinion in Gastroenterology 30:4, pages 352-358.
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Kenny Roman, Joseph D. Done, Anthony J. Schaeffer, Stephen F. Murphy & Praveen Thumbikat. (2014) Tryptase-PAR2 axis in experimental autoimmune prostatitis, a model for chronic pelvic pain syndrome. Pain 155:7, pages 1328-1338.
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Crossref
Gabrio Bassotti, Vincenzo Villanacci, Riccardo Nascimbeni, Elisabetta Antonelli, Moris Cadei, Stefania Manenti, Luisa Lorenzi, Amin Titi & Bruno Salerni. (2012) The role of colonic mast cells and myenteric plexitis in patients with diverticular disease. International Journal of Colorectal Disease 28:2, pages 267-272.
Crossref
Stephen J Halpin & Alexander C Ford. (2012) Prevalence of Symptoms Meeting Criteria for Irritable Bowel Syndrome in Inflammatory Bowel Disease: Systematic Review and Meta-Analysis. American Journal of Gastroenterology 107:10, pages 1474-1482.
Crossref
Arvind Iyengar Srinath, Chelsea Walter, Melissa C. Newara & Eva M. Szigethy. (2012) Pain management in patients with inflammatory bowel disease: insights for the clinician. Therapeutic Advances in Gastroenterology 5:5, pages 339-357.
Crossref
Bin Feng, Jun Ho La, Erica S. Schwartz & G. F. Gebhart. (2012) Irritable Bowel Syndrome: Methods, Mechanisms, and Pathophysiology. Neural and neuro-immune mechanisms of visceral hypersensitivity in irritable bowel syndrome. American Journal of Physiology-Gastrointestinal and Liver Physiology 302:10, pages G1085-G1098.
Crossref

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