Citations (22)
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Mie Grunnet, Dan Calatayud, Nicolai Aa Schultz, Jane P. Hasselby, Morten Mau-Sørensen, Nils Brünner & Jan Stenvang. (2015) TOP1 gene copy numbers are increased in cancers of the bile duct and pancreas. Scandinavian Journal of Gastroenterology 50:4, pages 485-494.
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Sune Boris Nygård, Ib Jarle Christensen, Signe Lykke Nielsen, Hans Jørgen Nielsen, Nils Brünner & Karen-Lise Garm Spindler. (2013) Assessment of the topoisomerase I gene copy number as a predictive biomarker of objective response to irinotecan in metastatic colorectal cancer. Scandinavian Journal of Gastroenterology 49:1, pages 84-91.
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Articles from other publishers (20)
Seobin Yoon, Bum-Kyu Lee & Keun Pil Kim. (2023) Caffeine enhances chemosensitivity to irinotecan in the treatment of colorectal cancer. Phytomedicine 121, pages 155120.
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Ahmed Mohamed Nabil Helaly & Doaa Ghorab. 2023. DNA Replication - Mechanisms, Epigenetics, and Gene Therapy Applications [Working Title]. DNA Replication - Mechanisms, Epigenetics, and Gene Therapy Applications [Working Title].
Dan Sarni, Sonia Barroso, Alon Shtrikman, Michal Irony-Tur Sinai, Yifat S. Oren, Andrés Aguilera & Batsheva Kerem. (2022) Topoisomerase 1-dependent R-loop deficiency drives accelerated replication and genomic instability. Cell Reports 40:13, pages 111397.
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Cinzia Tesauro, Anne Katrine Simonsen, Marie Bech Andersen, Kamilla Wandsoe Petersen, Emil Laust Kristoffersen, Line Algreen, Noriko Yokoyama Hansen, Anne Bech Andersen, Ann Katrine Jakobsen, Magnus Stougaard, Pavel Gromov, Birgitta R. Knudsen & Irina Gromova. (2019) Topoisomerase I activity and sensitivity to camptothecin in breast cancer-derived cells: a comparative study. BMC Cancer 19:1.
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Duarte Mendes Oliveira, Gianluca Santamaria, Carmelo Laudanna, Simona Migliozzi, Pietro Zoppoli, Michael Quist, Catie Grasso, Chiara Mignogna, Laura Elia, Maria Concetta Faniello, Cinzia Marinaro, Rosario Sacco, Francesco Corcione, Giuseppe Viglietto, Donatella Malanga & Antonia Rizzuto. (2018) Identification of copy number alterations in colon cancer from analysis of amplicon-based next generation sequencing data. Oncotarget 9:29, pages 20409-20425.
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Jesper Andreas Palshof, Estrid Vilma Solyom Høgdall, Tim Svenstrup Poulsen, Dorte Linnemann, Benny Vittrup Jensen, Per Pfeiffer, Line Schmidt Tarpgaard, Nils Brünner, Jan Stenvang, Mette Yilmaz & Dorte Lisbet Nielsen. (2017) Topoisomerase I copy number alterations as biomarker for irinotecan efficacy in metastatic colorectal cancer. BMC Cancer 17:1.
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Manish R. SharmaJames T. AumanNirali M. PatelJuneko E. Grilley-OlsonXiaobei ZhaoStergios J. MoschosJoel S. ParkerXiaoying YinMichele C. HaywardBlase N. PoliteElena MarangonBianca PosoccoGiuseppe ToffoliD. Neil HayesFederico Innocenti. (2017)
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Niels Frank Jensen, Keli Agama, Amit Roy, David Hersi Smith, Thomas D. Pfister, Maria Unni Rømer, Hong-Liang Zhang, James H. Doroshow, Birgitta R. Knudsen, Jan Stenvang, Nils Brünner & Yves Pommier. (2016) Characterization of DNA topoisomerase I in three SN-38 resistant human colon cancer cell lines reveals a new pair of resistance-associated mutations. Journal of Experimental & Clinical Cancer Research 35:1.
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Haatisha Jandu, Kristina Aluzaite, Louise Fogh, Sebastian Wingaard Thrane, Julie B. Noer, Joanna Proszek, Khoa Nguyen Do, Stine Ninel Hansen, Britt Damsgaard, Signe Lykke Nielsen, Magnus Stougaard, Birgitta R. Knudsen, José Moreira, Petra Hamerlik, Madhavsai Gajjar, Marcel Smid, John Martens, John Foekens, Yves Pommier, Nils Brünner, Anne-Sofie Schrohl & Jan Stenvang. (2016) Molecular characterization of irinotecan (SN-38) resistant human breast cancer cell lines. BMC Cancer 16:1.
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Jennifer J. Wheler, Filip Janku, Aung Naing, Yali Li, Bettzy Stephen, Ralph Zinner, Vivek Subbiah, Siqing Fu, Daniel Karp, Gerald S. Falchook, Apostolia M. Tsimberidou, Sarina Piha-Paul, Roosevelt Anderson, Danxia Ke, Vincent Miller, Roman Yelensky, J. Jack Lee, David S. Hong & Razelle Kurzrock. (2016) Cancer Therapy Directed by Comprehensive Genomic Profiling: A Single Center Study. Cancer Research 76:13, pages 3690-3701.
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Zoran Gatalica, Semir Vranic, Joanne Xiu, Jeffrey Swensen & Sandeep Reddy. (2016) High microsatellite instability (MSI-H) colorectal carcinoma: a brief review of predictive biomarkers in the era of personalized medicine. Familial Cancer 15:3, pages 405-412.
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Sune Boris Nygård, Ben Vainer, Signe Lykke Nielsen, Fred Bosman, Sabine Tejpar, Arnaud Roth, Mauro Delorenzi, Nils Brünner & Eva Budinska. (2016) DNA Topoisomerase I Gene Copy Number and mRNA Expression Assessed as Predictive Biomarkers for Adjuvant Irinotecan in Stage II/III Colon Cancer. Clinical Cancer Research 22:7, pages 1621-1631.
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Iben Kümler, Eva Balslev, Jan Stenvang, Nils Brünner & Dorte Nielsen. (2015) A phase II study of weekly irinotecan in patients with locally advanced or metastatic HER2- negative breast cancer and increased copy numbers of the topoisomerase 1 (TOP1) gene: a study protocol. BMC Cancer 15:1.
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Iben Kümler, Eva Balslev, Tim S. Poulsen, Signe Lykke Nielsen, Sune Boris Nygård, Maria Unni Rømer, Ib Jarle Christensen, Estrid Høgdall, José Moreira, Dorte L. Nielsen, Nils Brünner & Jan Stenvang. (2015) Topoisomerase-1 gene copy aberrations are frequent in patients with breast cancer. International Journal of Cancer 137:8, pages 2000-2006.
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David Hersi Smith, Anne-Marie Kanstrup Fiehn, Louise Fogh, Ib Jarle Christensen, Tine Plato Hansen, Jan Stenvang, Hans Jørgen Nielsen, Kirsten Vang Nielsen, Jane Preuss Hasselby, Nils Brünner & Sussie Steen Jensen. (2014) Measuring ERCC1 protein expression in cancer specimens: Validation of a novel antibody. Scientific Reports 4:1.
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Hai-Ping Zhang, Jian-Bo Pan, Chi Zhang, Nan Ji, Hao Wang & Zhi-Liang Ji. (2014) Network Understanding of Herb Medicine via Rapid Identification of Ingredient-Target Interactions. Scientific Reports 4:1.
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David Hersi Smith, Ib Jarle Christensen, Niels Frank Jensen, Bo Markussen, Maria Unni Rømer, Sune Boris Nygård, Sven Müller, Hans Jørgen Nielsen, Nils Brünner & Kirsten Vang Nielsen. (2013) Mechanisms of Topoisomerase I (TOP1) Gene Copy Number Increase in a Stage III Colorectal Cancer Patient Cohort. PLoS ONE 8:4, pages e60613.
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Iben Kümler, Nils Brünner, Jan Stenvang, Eva Balslev & Dorte L. Nielsen. (2013) A systematic review on topoisomerase 1 inhibition in the treatment of metastatic breast cancer. Breast Cancer Research and Treatment 138:2, pages 347-358.
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Maria Unni Rømer, Sune Boris Nygård, Ib Jarle Christensen, Signe Lykke Nielsen, Kirsten Vang Nielsen, Sven Müller, David Hersi Smith, Ben Vainer, Hans Jørgen Nielsen & Nils Brünner. (2012)
Topoisomerase 1(
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Bum Hee LeeSangyoung RohYu Im KimAhwon LeeSu Young Kim. (2012) Difference of Genome-Wide Copy Number Alterations between High-Grade Squamous Intraepithelial Lesions and Squamous Cell Carcinomas of the Uterine Cervix. Korean Journal of Pathology 46:2, pages 123.
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