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Gastrointestinal Cancer

Hepatocellular carcinoma as extracolonic manifestation of Lynch syndrome indicates SEC63 as potential target gene in hepatocarcinogenesis

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Pages 344-351 | Received 16 Sep 2012, Accepted 18 Nov 2012, Published online: 05 Feb 2013

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Read on this site (3)

Huijie Gao, Weibo Niu, Zhaobin He, Chao Gao, Cheng Peng & Jun Niu. (2020) SEC61G plays an oncogenic role in hepatocellular carcinoma cells. Cell Cycle 19:23, pages 3348-3361.
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Ying Liu, Xiaolin Zhang, Jinhai Jia, Longmei Tang, Xia Gao, Lina Yan, Liqin Wang, Fengxue Yu, Ning Ma, Wenxuan Liu, Lei Yang, Xuehui Liu & Dianwu Liu. (2015) Correlation between polymorphisms in DNA mismatch repair genes and the risk of primary hepatocellular carcinoma for the Han population in northern China. Scandinavian Journal of Gastroenterology 50:11, pages 1404-1410.
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S. S. Song, P. F. Yuan, P. P. Li, H. X. Wu, W. J. Ni, J. T. Lu & W. Wei. (2015) Protective Effects of Total Glucosides of Paeony on N-nitrosodiethylamine-induced Hepatocellular Carcinoma in Rats via Down-regulation of Regulatory B Cells. Immunological Investigations 44:6, pages 521-535.
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Yucheng Meng, Ke Huang, Mingxuan Shi, Yifei Huo, Liang Han, Bin Liu & Yi Li. (2023) Research Advances in the Role of the Tropomyosin Family in Cancer. International Journal of Molecular Sciences 24:17, pages 13295.
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Shanqi Xu, Xin Li, Jianxiong Geng, Yingyue Cao, Yan Yu & Lishuang Qi. (2023) Sec61γ is a vital protein in the endoplasmic reticulum membrane promoting tumor metastasis and invasion in lung adenocarcinoma. British Journal of Cancer 128:8, pages 1478-1490.
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Julia S. M. Zimmermann, Johannes Linxweiler, Julia C. Radosa, Maximilian Linxweiler & Richard Zimmermann. (2022) The endoplasmic reticulum membrane protein Sec62 as potential therapeutic target in SEC62 overexpressing tumors. Frontiers in Physiology 13.
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Osiris Germán Idelfonso-García, Brisa Rodope Alarcón-Sánchez, Verónica Rocío Vásquez-Garzón, Rafael Baltiérrez-Hoyos, Saúl Villa-Treviño, Pablo Muriel, Héctor Serrano, Julio Isael Pérez-Carreón & Jaime Arellanes-Robledo. (2022) Is Nucleoredoxin a Master Regulator of Cellular Redox Homeostasis? Its Implication in Different Pathologies. Antioxidants 11:4, pages 670.
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Yidi Zhao, Qingya Song, Fangshi Xu, Yang Zhou, Xiaoli Zuo & Zhengliang Zhang. (2022) Pyroptosis-Related Risk Signature Exhibits Distinct Prognostic, Immune, and Therapeutic Landscapes in Hepatocellular Carcinoma. Frontiers in Genetics 13.
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Qunhao Zheng, Zhiping Wang, Mengyan Zhang, Yilin Yu, Rui Chen, Tianzhu Lu, Lingyun Liu, Jiayu Ma, Tianxiu Liu, Hongying Zheng, Hui Li & Jiancheng Li. (2021) Prognostic value of SEC61G in lung adenocarcinoma: a comprehensive study based on bioinformatics and in vitro validation. BMC Cancer 21:1.
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Mark Sicking, Sven Lang, Florian Bochen, Andreas Roos, Joost P. H. Drenth, Muhammad Zakaria, Richard Zimmermann & Maximilian Linxweiler. (2021) Complexity and Specificity of Sec61-Channelopathies: Human Diseases Affecting Gating of the Sec61 Complex. Cells 10:5, pages 1036.
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Rhys Gillman, Kylie Lopes Floro, Miriam Wankell & Lionel Hebbard. (2021) The role of DNA damage and repair in liver cancer. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 1875:1, pages 188493.
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Xuyang Gong & Ailong Huang. (2020) Differential expression and diagnostic significance of P53, MutS homologs 2, tropomyosin‐4 in alpha‐fetoprotein‐negative hepatocellular carcinoma. Journal of Clinical Laboratory Analysis 34:8.
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Amir Valizadeh, Roozbeh Sanaei, Nima Rezaei, Gholamreza Azizi, Saba Fekrvand, Asghar Aghamohammadi & Reza Yazdani. (2019) Potential role of regulatory B cells in immunological diseases. Immunology Letters 215, pages 48-59.
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Yu Feng, Yufeng Cao, Mingming Yuan, Rongrong Chen, Xue Ji & Xingsheng Hu. (2019) Different responses to anti‑programmed cell death protein 1 (PD‑1) immunotherapy in a patient with Lynch syndrome and metachronous urothelial and colon cancer: A case report. Oncology Letters.
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Kai Bachmann, Maximillian Bockhorn, Oliver Mann, Florian Gebauer, Marco Blessmann, Jakob Robert Izbicki & Katharina Grupp. (2019) Aberrant expression of Sec61α in esophageal cancers. Journal of Cancer Research and Clinical Oncology 145:8, pages 2039-2044.
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Ahmad Abdullah, Priti Talwar, Christian Lefebvre d'Hellencourt & Palaniyandi Ravanan. (2019) IRE 1α is critical for Kaempferol‐induced neuroblastoma differentiation . The FEBS Journal 286:7, pages 1375-1392.
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Maximilian Linxweiler, Bernhard Schick & Richard Zimmermann. (2017) Let’s talk about Secs: Sec61, Sec62 and Sec63 in signal transduction, oncology and personalized medicine. Signal Transduction and Targeted Therapy 2:1.
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Takahito Moriwaki, Yuichi Kato, Chihiro Nakamura, Satoru Ishikawa & Qiu-Mei Zhang-Akiyama. (2015) A novel DNA damage response mediated by DNA mismatch repair in Caenorhabditis elegans: induction of programmed autophagic cell death in non-dividing cells. Genes & Cancer 6:7-8, pages 341-355.
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