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Scandinavian Journal of Gastroenterology Volume 50, 2015 - Issue 5
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Original Article

Pro-C5, a marker of true type V collagen formation and fibrillation, correlates with portal hypertension in patients with alcoholic cirrhosis

Diana J. LeemingNordic Bioscience, Fibrosis Biology and Biomarkers, Herlev, DenmarkCorrespondence[email protected]
,
Sanne S. VeidalNordic Bioscience, Fibrosis Biology and Biomarkers, Herlev, Denmark;University of Southern Denmark, The Faculty of Health Science, Odense, Denmark
,
Morten A. KarsdalNordic Bioscience, Fibrosis Biology and Biomarkers, Herlev, Denmark;University of Southern Denmark, The Faculty of Health Science, Odense, Denmark
,
Mette Juul NielsenNordic Bioscience, Fibrosis Biology and Biomarkers, Herlev, Denmark;Department of Gastroenterology, Odense University Hospital, University of Southern Denmark, Odense, Denmark
,
Jonel TrebickaDepartment of Internal Medicine I, University of Bonn, Bonn, Germany
,
Troels BuskSection of Clinical Physiology and Nuclear Medicine, Centre of functional Imaging and Research, Hvidovre Hospital and Faculty of Health Sciences, University of Copenhagen, Hvidovre, Denmark
,
Flemming BendtsenDepartment of Gastroenterology, Hvidovre Hospital and Faculty of Health Sciences, University of Copenhagen, Hvidovre, Denmark
,
Aleksander KragDepartment of Gastroenterology, Hvidovre Hospital and Faculty of Health Sciences, University of Copenhagen, Hvidovre, Denmark;Department of Gastroenterology, Odense University Hospital, University of Southern Denmark, Odense, Denmark
&
Søren MøllerSection of Clinical Physiology and Nuclear Medicine, Centre of functional Imaging and Research, Hvidovre Hospital and Faculty of Health Sciences, University of Copenhagen, Hvidovre, Denmark
 show all
Pages 584-592 | Received 13 Oct 2014, Accepted 28 Nov 2014, Published online: 01 Feb 2015

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N. Kimer, S. Wiese, S. Mo, S. Møller & F. Bendtsen. (2016) Advances in the treatment of portal hypertension in cirrhosis. Expert Review of Gastroenterology & Hepatology 10:8, pages 961-969.
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Federica Genovese & Morten Asser Karsdal. (2016) Protein degradation fragments as diagnostic and prognostic biomarkers of connective tissue diseases: understanding the extracellular matrix message and implication for current and future serological biomarkers. Expert Review of Proteomics 13:2, pages 213-225.
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Articles from other publishers (37)

Jeppe Thorlacius‐Ussing, Christina Jensen, Neel I Nissen, Thomas R Cox, Raghu Kalluri, Morten Karsdal & Nicholas Willumsen. (2023) The collagen landscape in cancer: profiling collagens in tumors and in circulation reveals novel markers of cancer‐associated fibroblast subtypes. The Journal of Pathology 262:1, pages 22-36.
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Maximilian Joseph Brol, Juliana Gödiker, Frank Erhard Uschner, Michael Praktiknjo & Jonel Trebicka. (2023) Non-invasive Assessment of Clinically Significant Portal Hypertension. Current Hepatology Reports 22:3, pages 206-215.
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Neel I. Nissen, Astrid Z. Johansen, Inna M. Chen, Christina Jensen, Emilie A. Madsen, Carsten P. Hansen, Jeppe Thorlacius-Ussing, Morten Karsdal, Julia S. Johansen, Hadi M. H. Diab, Lars N. Jørgensen & Nicholas Willumsen. (2023) High serum levels of the C-propetide of type V collagen (PRO-C5) are prognostic for short overall survival in patients with pancreatic ductal adenocarcinoma. Frontiers in Molecular Biosciences 10.
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Leona Dold, Mette J. Nielsen, Michael Praktiknjo, Carolynne Schwarze-Zander, Christoph Boesecke, Jan-Christian Wasmuth, Jenny Bischoff, Jürgen Kurt Rockstroh, Morten A. Karsdal, Ulrich Spengler, Jonel Trebicka, Christian P. Strassburg, Diana J. Leeming & Bettina Langhans. (2023) Circulating levels of endotrophin and cross-linked type III collagen reflect liver fibrosis in people with HIV. BMC Infectious Diseases 23:1.
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Johannes Chang, Jonathan Meinke, Moritz Geck, Marc Hebest, Nina Böhling, Ramona Dolscheid-Pommerich, Birgit Stoffel-Wagner, Glen Kristiansen, Marcus Overhaus, Leon O. Peyman, Sabine Klein, Frank E. Uschner, Maximilian J. Brol, Tim O. Vilz, Philipp Lingohr, Jörg C. Kalff, Christian Jansen, Christian P. Strassburg, Sven Wehner, Jonel Trebicka & Michael Praktiknjo. (2021) Extrahepatic Surgery in Cirrhosis Significantly Increases Portal Pressure in Preclinical Animal Models. Frontiers in Physiology 12.
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Yasuko Iwakiri & Jonel Trebicka. (2021) Portal hypertension in cirrhosis: Pathophysiological mechanisms and therapy. JHEP Reports 3:4, pages 100316.
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M.A. Karsdal. 2019. Biochemistry of Collagens, Laminins and Elastin. Biochemistry of Collagens, Laminins and Elastin xxiii xliv .
D.J. Leeming & M.A. Karsdal. 2019. Biochemistry of Collagens, Laminins and Elastin. Biochemistry of Collagens, Laminins and Elastin 51 57 .
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Cheng-Jie Lin, Zhi-Gao Hu, Guan-Dou Yuan, Biao Lei & Song-Qing He. (2018) Complements are involved in alcoholic fatty liver disease, hepatitis and fibrosis. World Journal of Hepatology 10:10, pages 662-669.
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Xiaolong Qi, Annalisa Berzigotti, Andres Cardenas & Shiv Kumar Sarin. (2018) Emerging non-invasive approaches for diagnosis and monitoring of portal hypertension. The Lancet Gastroenterology & Hepatology 3:10, pages 708-719.
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Yi Luo, Abdul Oseini, Robert Gagnon, Edgar D. Charles, Kurex Sidik, Robert Vincent, Rebeca Collen, Michael Idowu, Melissa J. Contos, Faridoddin Mirshahi, Kalyani Daita, Amon Asgharpour, Mohammed S. Siddiqui, Gabor Jarai, Glenn Rosen, Rose Christian & Arun J. Sanyal. (2018) An Evaluation of the Collagen Fragments Related to Fibrogenesis and Fibrolysis in Nonalcoholic Steatohepatitis. Scientific Reports 8:1.
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T. Manon-Jensen, B. L. Hua, E. H. N. Olsen, S. Sun, C. N. Gudme, J. Li, W. Lei, B. Vandahl, K. Roepstorff, M. Kjelgaard-Hansen, Y. Zhao & M. A. Karsdal. (2017) Increased basement membrane turnover and strongly attenuated interstitial matrix turnover is a key pathological feature of haemophilia. Haemophilia 23:6, pages e515-e518.
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Mette J. Nielsen, Diana J. Leeming, Morten A. Karsdal & Aleksander Krag. 2017. Biomarkers in Liver Disease. Biomarkers in Liver Disease 221 246 .
T. Manon‐Jensen, M.A. Karsdal, L.N. Nielsen, M. Kjelgaard‐Hansen, B. Vandahl, E.H.N. Olsen, M. Enoksson & K. Roepstorff. (2016) Altered collagen turnover in factor VIII‐deficient rats with hemophilic arthropathy identifies potential novel serological biomarkers in hemophilia. Journal of Thrombosis and Haemostasis 14:12, pages 2419-2429.
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Lauren G. Poole & Gavin E. Arteel. (2016) Transitional Remodeling of the Hepatic Extracellular Matrix in Alcohol-Induced Liver Injury. BioMed Research International 2016, pages 1-10.
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D.J. Leeming & M.A. Karsdal. 2016. Biochemistry of Collagens, Laminins and Elastin. Biochemistry of Collagens, Laminins and Elastin 43 48 .
Mette J. Nielsen, Diana J. Leeming, Morten A. Karsdal & Aleksander Krag. 2016. Biomarkers in Liver Disease. Biomarkers in Liver Disease 1 26 .

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