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Scandinavian Journal of Gastroenterology Volume 15, 1980 - Issue 5
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Original Article

Serum Phospholipase A2 in Human Acute Pancreatitis

T. Schröder Second Dept. of Surgery and Dept. of Medical Chemistry, University of Helsinki, Helsinki, Finland
,
E. Kivilaakso Second Dept. of Surgery and Dept. of Medical Chemistry, University of Helsinki, Helsinki, Finland
,
P. K. J. Kinnunen Second Dept. of Surgery and Dept. of Medical Chemistry, University of Helsinki, Helsinki, Finland
&
M. Lempinen Second Dept. of Surgery and Dept. of Medical Chemistry, University of Helsinki, Helsinki, Finland
Pages 633-636 | Received 21 Jan 1980, Accepted 12 Feb 1980, Published online: 23 Feb 2010

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Anu Mäkelä, Timo Kuusi, Pekka Nuutinen & Tom Schröder. (1999) Phospholipase A2 Activity in Body Fluids and Pancreatic Tissue in Patients with Acute Necrotising Pancreatitis. The European Journal of Surgery 165:1, pages 35-42.
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Erich Kaiser. (1999) Phospholipase A2: Its Usefulness in Laboratory Diagnostics. Critical Reviews in Clinical Laboratory Sciences 36:2, pages 65-163.
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A. Mäkelä, T. Kuusi & T. Schröder. (1997) Inhibition of serum phospholipase-A2 in acute pancreatitis by pharmacological agents in vitro. Scandinavian Journal of Clinical and Laboratory Investigation 57:5, pages 401-407.
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N-E. L. Saris, B. Steinbrückner, T. Thurén, M. L. T. Lalla, H. van den Bosch, P. K. J. Kinnunen & G. E. Hoffmann. (1992) Characterization of cellular and elevated serum phospholipase A2 activities with a comparison of two methods. Scandinavian Journal of Clinical and Laboratory Investigation 52:1, pages 19-25.
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A. Mäkelä, B. Sternby, T. Kuusi, P. Puolakkainen & T. Schröder. (1990) Phospholipase A2 Activity and Concentration in Several Body Fluids in Patients with Acute Pancreatitis. Scandinavian Journal of Gastroenterology 25:9, pages 944-950.
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B. Van Ooijen, R. J. T. Ouwendijk, W. J. Kort, F. J. Zijlstra, J. E. Vincent, J. H. P. Wilson & D. L. Westbroek. (1988) Raised Plasma Thromboxane B2 Levels in Experimental Acute Necrotizing Pancreatitis in Rats: The Effects of Flunarizine, Dazoxiben, and Indomethacin. Scandinavian Journal of Gastroenterology 23:2, pages 188-192.
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Timo J. Nevalainen. (1988) Phospholipase A2 in Acute Pancreatitis. Scandinavian Journal of Gastroenterology 23:8, pages 897-904.
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P. Puolakkainen, A. Paananen, M. Kaarne, T. Kuusi, M. Lempinen & T. Schröder. (1987) Aprotinin and Na2CaEDTA in Experimental Hemorrhagic Pancreatitis in Pigs. Scandinavian Journal of Gastroenterology 22:1, pages 35-41.
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Anu Mäkelä, Timo Kuusi, Pentti Somerharju & Tom Schröder. (1987) A simple isotopic assay method for human serum phospholipase A2 activity. Scandinavian Journal of Clinical and Laboratory Investigation 47:6, pages 529-534.
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M. Mero, T. Schröder, R. Tenhunen & M. Lempinen. (1982) Serum Phospholipase A2, Immunoreactive Trypsin, and Trypsin Inhibitors During Human Acute Pancreatitis. Scandinavian Journal of Gastroenterology 17:3, pages 413-416.
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T. Schröder. (1982) The Effect of Early Pancreatectomy and Peritoneal Lavage on the Development of Experimental Haemorrhagic Pancreatitis in Pigs. Scandinavian Journal of Gastroenterology 17:2, pages 167-171.
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John A. Lott & H. D. Gruemer. (1982) Inflammatory Diseases of the Pancreas. CRC Critical Reviews in Clinical Laboratory Sciences 17:3, pages 201-228.
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Fred S. Gorelick & Markus M. Lerch. (2017) Do Animal Models of Acute Pancreatitis Reproduce Human Disease?. Cellular and Molecular Gastroenterology and Hepatology 4:2, pages 251-262.
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Soraia K. P. Costa, Enilton A. Camargo & Edson Antunes. 2017. Toxins and Drug Discovery. Toxins and Drug Discovery 35 52 .
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Christian Code, Ajay K. Mahalka, Kristian Bry & Paavo K.J. Kinnunen. (2010) Activation of phospholipase A2 by 1-palmitoyl-2-(9'-oxo-nonanoyl)-sn-glycero-3-phosphocholine in vitro. Biochimica et Biophysica Acta (BBA) - Biomembranes 1798:8, pages 1593-1600.
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Timo J. Nevalainen. (2007) Phospholipase A2 in acute pancreatitis: review. The American Journal of Surgery 194:4, pages S28-S32.
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Massimo Triggiani, Francescopaolo Granata, Annunziata Frattini & Gianni Marone. (2006) Activation of human inflammatory cells by secreted phospholipases A2. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1761:11, pages 1289-1300.
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ChuHee Lee, Jingu Lee, Young-Ae Choi, Shin-Sung Kang & Suk-Hwan Baek. (2006) cAMP elevating agents suppress secretory phospholipase A2-induced matrix metalloproteinase-2 activation. Biochemical and Biophysical Research Communications 340:4, pages 1278-1283.
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N C Bird, A J Goodman & A G Johnson. (1989) Serum phospholipase A2 activity in acute pancreatitis: An early guide to severity. British Journal of Surgery 76:7, pages 731-732.
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H G Beger, M Büchler, R Bittner, S Block, T Nevalainen & R Roscher. (1988) Necrosectomy and postoperative local lavage in necrotizing pancreatitis. British Journal of Surgery 75:3, pages 207-212.
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L J Formela, S W Galloway & A N Kingsnorth. (1995) Inflammatory mediators in acute pancreatitis. British Journal of Surgery 82:1, pages 6-13.
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Francescopaolo Granata, Angelica Petraroli, Eric Boilard, Sofiane Bezzine, James Bollinger, Luigi Del Vecchio, Michael H. Gelb, Gerard Lambeau, Gianni Marone & Massimo Triggiani. (2005) Activation of Cytokine Production by Secreted Phospholipase A2 in Human Lung Macrophages Expressing the M-Type Receptor. The Journal of Immunology 174:1, pages 464-474.
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C.F.P Teixeira, E.C.T Landucci, E Antunes, M Chacur & Y Cury. (2003) Inflammatory effects of snake venom myotoxic phospholipases A2. Toxicon 42:8, pages 947-962.
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Massimo Triggiani, Francescopaolo Granata, Barbara Balestrieri, Angelica Petraroli, Giulia Scalia, Luigi Del Vecchio & Gianni Marone. (2003) Secretory Phospholipases A2 Activate Selective Functions in Human Eosinophils. The Journal of Immunology 170:6, pages 3279-3288.
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Jens Werner, Werner Hartwig, Waldemar Uhl, Christophe Müller & Markus W. Büchler. (2003) Useful Markers for Predicting Severity and Monitoring Progression of Acute Pancreatitis. Pancreatology 3:2, pages 115-127.
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Dhiraj Yadav, N. Agarwal & C.S. Pitchumoni. (2002) A critical evaluation of laboratory tests in acute pancreatitis. The American Journal of Gastroenterology 97:6, pages 1309-1318.
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Massimo Triggiani, Francescopaolo Granata, Alfonso Oriente, Marco Gentile, Angelica Petraroli, Barbara Balestrieri & Gianni Marone. (2002) Secretory phospholipases A2 induce cytokine release from blood and synovial fluid monocytes. European Journal of Immunology 32:1, pages 67-76.
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Olga Mizenina, Elena Musatkina, Yuriy Yanushevich, Anna Rodina, Michail Krasilnikov, Jean de Gunzburg, Jacques H. Camonis, Armand Tavitian & Alexander Tatosyan. (2001) A Novel Group IIA Phospholipase A2Interacts with v-Src Oncoprotein from RSV-transformed Hamster Cells. Journal of Biological Chemistry 276:36, pages 34006-34012.
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Krystyna Sztefko & Józefa Panek. (2001) Serum Free Fatty Acid Concentration in Patients with Acute Pancreatitis. Pancreatology 1:3, pages 230-236.
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Elen C.T Landucci, Rogerio C Castro, Maristela F Pereira, Adelia C.O Cintra, Jose R Giglio, Sergio Marangoni, Benedito Oliveira, Giuseppe Cirino, Edson Antunes & Gilberto De Nucci. (1998) Mast cell degranulation induced by two phospholipase A2 homologues: Dissociation between enzymatic and biological activities. European Journal of Pharmacology 343:2-3, pages 257-263.
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Jay A. Tischfield. (1997) A Reassessment of the Low Molecular Weight Phospholipase A2 Gene Family in Mammals. Journal of Biological Chemistry 272:28, pages 17247-17250.
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Srinivasa T. Reddy, Michelle V. Winstead, Jay A. Tischfield & Harvey R. Herschman. (1997) Analysis of the Secretory Phospholipase A2 That Mediates Prostaglandin Production in Mast Cells. Journal of Biological Chemistry 272:21, pages 13591-13596.
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Yuping Yuan, Simone M. Schoenwaelder, Hatem H. Salem & Shaun P. Jackson. (1996) The Bioactive Phospholipid, Lysophosphatidylcholine, Induces Cellular Effects via G-Protein-dependent Activation of Adenylyl Cyclase. Journal of Biological Chemistry 271:43, pages 27090-27098.
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Rikard Berling & Kjell Ohlsson. (1996) Effects of high-dose intraperitoneal aprotinin treatment on complement activation and acute phase response in acute severe pancreatitis. Journal of Gastroenterology 31:5, pages 702-709.
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Tetsuro Nakamura, Akira Okada, Jun Higaki, Hiromasa Tojo & Mitsuhiro Okamoto. (2014) Pancreaticobiliary Maljunction-Associated Pancreatitis: An Experimental Study on the Activation of Pancreatic Phospholipase A2. World Journal of Surgery 20:5, pages 543-550.
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Sergio Lloret & Juan José Moreno. (1994) Immunochemical relatedness between secretory phospholipase A2 and intracellular phospholipase A2 activity linked with arachidonic acid mobilization in macrophages. Toxicon 32:11, pages 1327-1336.
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Timo J. Nevalainen & Juha M. Grönroos. 1994. Esterases, Lipases, and Phospholipases. Esterases, Lipases, and Phospholipases 253 261 .
Timo J. Nevalainen & Timo J. Haapanen. (1993) Distribution of pancreatic (group I) and synovial-type (group II) phospholipases A2 in human tissues. Inflammation 17:4, pages 453-464.
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Akihiro Funakoshi, Yukio Yamada, Yoshikatsu Migita & Hideyuki Wakasugi. (1993) Simultaneous determinations of pancreatic phospholipase A2 and prophospholipase A2 in various pancreatic diseases. Digestive Diseases and Sciences 38:3, pages 502-506.
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Heikki J. Peuravuori, Hitoshi Funatomi & Timo J. Nevalainen. (1993) Group I and Group II Phospholipases A2 in Serum in Uraemia. Clinical Chemistry and Laboratory Medicine 31:8.
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Renate Th. Hiefinger-Schindlbeck, C. Dasser, Christa Hübner-Parajsz, G. E. Hoffmann & W. G. Guder. (1993) Differentiation of Human Phospholipase A2 Isoenzymes in Serum and Other Body Fluids with Use of Monoclonal Antibodies. Clinical Chemistry and Laboratory Medicine 31:4.
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Akiko Kanda, Mikio Tamaki, Etsuo Nakamura, Hiroshi Teraoka & Nobuo Yoshida. (1992) Characterization of recombinant human and rat pancreatic phospholipases A2 secreted from Saccharomyces cerevisiae: Difference in proteolytic processing. Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression 1171:1, pages 1-10.
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Lillian L. L. Leong, Marian J. Sturm, Yahya Ismail, Charlene J. Stephens & Roger R. Taylor. (2007) PLASMA PHOSPHOLIPASE A 2 ACTIVITY IN CLINICAL ACUTE MYOCARDIAL INFARCTION . Clinical and Experimental Pharmacology and Physiology 19:2, pages 113-118.
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Cheryl R. Stoner, Linda M. Reik, Mary Donohue, Wayne Levin & Robert M. Crowl. (1991) Human group II phospholipase A2. Journal of Immunological Methods 145:1-2, pages 127-136.
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Simon R. Langton & Joanne Dench. (1991) Phospholipase A2 is associated with albumin in patients with acute pancreatitis. Clinica Chimica Acta 203:2-3, pages 249-257.
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Motoji Kitagawa, Tetsuo Hayakawa, Takaharu Kondo, Tokimune Shibata, Yuzo Sakai, Hiroshi Sobajima, Hiroshi Ishiguro, Makoto Tanikawa, Yasuyuki Nakae, Saeko Kameya & Aiji Noda. (1991) Elevation of serum phospholipase A2 in patients at an intensive care unit. International journal of pancreatology 10:3-4, pages 279-286.
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Motoji Kitagawa, Tetsuo Hayakawa, Takaharu Kondo, Tokimune Shibata, Yuzo Sakai, Hiroshi Sobajima, Hiroshi Ishiguro & Yasuyuki Nakae. (1991) The diagnostic value of serum pancreatic phospholipase A2 (PLA2) in pancreatic diseases. Gastroenterologia Japonica 26:1, pages 62-68.
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