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Original Article

Effect of Cimetidine on the Absorption of Vitamin B12

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Pages 129-131 | Received 15 Oct 1981, Accepted 30 Jun 1981, Published online: 19 Feb 2010

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Read on this site (5)

E. Kittang & H. Schjønsby. (1987) Effect of Gastric Anacidity on the Release of Cobalamins from Food and Their Subsequent Binding to R-Protein. Scandinavian Journal of Gastroenterology 22:9, pages 1031-1037.
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E. Kittang, E. Aadland, H. Schjønsby & K. Røhss. (1987) The Effect of Omeprazole on Gastric Acidity and the Absorption of Liver Cobalamins. Scandinavian Journal of Gastroenterology 22:2, pages 156-160.
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H. R. Koelz. (1986) Protective Drugs in the Treatment of Gastroduodenal Ulcer Disease. Scandinavian Journal of Gastroenterology 21:sup125, pages 156-164.
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E. Kittang, B. Hamborg & H. Schjosnsby. (1985) Absorption of Food Cobalamins Assessed by the Double-Isotope Method in Healthy Volunteers and in Patients with Chronic Diarrhoea. Scandinavian Journal of Gastroenterology 20:4, pages 500-507.
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B. Hamborg, E. Kittang & H. Schjønsby. (1985) The Effect of Ranitidine on the Absorption of Food Cobalamins. Scandinavian Journal of Gastroenterology 20:6, pages 756-758.
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Avat Taherpour & Razieh Rahimizadeh. (2016) Study of solvent effects on structural and conformational properties of cimetidine tautomers. Medicinal Chemistry Research 25:9, pages 2042-2057.
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N. Presse, S. Perreault & Marie-Jeanne Kergoat. (2015) Vitamin B12 deficiency induced by the use of gastric acid inhibitors: Calcium supplements as a potential effect modifier. The journal of nutrition, health & aging 20:5, pages 569-573.
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Matthew J. Zdilla. (2015) Metformin With Either Histamine H2-Receptor Antagonists or Proton Pump Inhibitors: A Polypharmacy Recipe for Neuropathy via Vitamin B12 Depletion. Clinical Diabetes 33:2, pages 90-95.
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S. B. Jung, V. Nagaraja, A. Kapur & G. D. Eslick. (2015) Association between vitamin B12 deficiency and long-term use of acid-lowering agents: a systematic review and meta-analysis. Internal Medicine Journal 45:4, pages 409-416.
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Avat Arman Taherpour, Ayoub Mozafai, Shahram Ranjbar & Sepehr Taban. (2014) A study of the effects of solvent on structural and conformational properties of ranitidine tautomer forms by DFT method. Structural Chemistry 26:2, pages 517-529.
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Shounak Majumder, Jose Soriano, Allan Louie Cruz & Constantin A. Dasanu. (2013) Vitamin B12 deficiency in patients undergoing bariatric surgery: Preventive strategies and key recommendations. Surgery for Obesity and Related Diseases 9:6, pages 1013-1019.
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T.S. Dharmarajan, Madhusudhana R. Kanagala, Padmavathi Murakonda, Ahna S. Lebelt & Edward P. Norkus. (2008) Do Acid-Lowering Agents Affect Vitamin B12 Status in Older Adults?. Journal of the American Medical Directors Association 9:3, pages 162-167.
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Joseph I. Boullata. 2005. Preventive Nutrition. Preventive Nutrition 833 868 .
Robert J Valuck & J.Mark Ruscin. (2004) A case-control study on adverse effects: H2 blocker or proton pump inhibitor use and risk of vitamin B12 deficiency in older adults. Journal of Clinical Epidemiology 57:4, pages 422-428.
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Alison K. Campbell, Lindsay H. Allen, Joshua W. Miller, Ralph Green & Mary N. Haan. (2003) Plasma Vitamin B-12 Concentrations in an Elderly Latino Population Are Predicted by Serum Gastrin Concentrations and Crystalline Vitamin B-12 Intake. The Journal of Nutrition 133:9, pages 2770-2776.
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Wolfgang Herrmann, Rima Obeid & Muhidien Jouma. (2003) Hyperhomocysteinemia and vitamin B-12 deficiency are more striking in Syrians than in Germans—causes and implications. Atherosclerosis 166:1, pages 143-150.
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J Mark Ruscin, Robert Lee PageIIII & Robert J Valuck. (2016) Vitamin B 12 Deficiency Associated with Histamine 2 -Receptor Antagonists and a Proton-Pump Inhibitor . Annals of Pharmacotherapy 36:5, pages 812-816.
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Ralph Carmel. (2000) Current Concepts in Cobalamin Deficiency. Annual Review of Medicine 51:1, pages 357-375.
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Lindgren, Kilander, Bagge & Nexø. (1999) Holotranscobalamin - a sensitive marker of cobalamin malabsorption. European Journal of Clinical Investigation 29:4, pages 321-329.
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SAGAR, JANCZEWSKA, LJUNGDAHL, BERTILSSON & SEENSALU. (1999) Effect of CYP2C19 polymorphism on serum levels of vitamin B 12 in patients on long-term omeprazole treatment . Alimentary Pharmacology & Therapeutics 13:4, pages 453-458.
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Basel Termanini, Fathia Gibril, Vincent E Sutliff, Fang Yu, David J Venzon & Robert T Jensen. (1998) Effect of Long-Term Gastric Acid Suppressive Therapy on Serum Vitamin B12 Levels in Patients with Zollinger-Ellison Syndrome. The American Journal of Medicine 104:5, pages 422-430.
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Ralph Carmel. (1995) 10 Malabsorption of food cobalamin. Baillière's Clinical Haematology 8:3, pages 639-655.
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R. F. McCloy, R. Arnold, K. D. Bardhan, D. Cattan, E. Klinkenberg-Knol, P. N. Maton, R. H. Riddell, P. Sipponen & A. Walan. (1995) Pathophysiological effects of long-term acid suppression in man. Digestive Diseases and Sciences 40:S2, pages 96S-120S.
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Harry C. Sax. (2016) Gastric Acid Secretion and Vitamin B 12 Absorption After Vertical Ronx-en-Y Gastric Bypass for Morbid Obesity. Journal of Parenteral and Enteral Nutrition 18:5, pages 470-470.
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Kevin E. Behrns, C. Daniel Smith & Michael G. Sarr. (1994) Prospective evaluation of gastric acid secretion and cobalamin absorption following gastric bypass for clinically severe obesity. Digestive Diseases and Sciences 39:2, pages 315-320.
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H. KOOP. (2007) Review article: metabolic consequences of long‐term inhibition of acid secretion by omeprazole. Alimentary Pharmacology & Therapeutics 6:4, pages 399-406.
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Henry M. MiddletonIIIIII. (1986) Intestinal hydrolysis of pyridoxal 5′-phosphate in vitro and in vivo in the rat. Gastroenterology 91:2, pages 343-350.
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J. Pension & K. G. Wormsley. (2012) Adverse Reactions and Interactions with H2-Receptor Antagonists. Medical Toxicology 1:3, pages 192-216.
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Mitchell Nazario. (2016) The Hepatic and Renal Mechanisms of Drug Interactions with Cimetidine. Drug Intelligence & Clinical Pharmacy 20:5, pages 342-348.
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E Kittang, E Aadland & H Schjonsby. (1985) Effect of omeprazole on the secretion of intrinsic factor, gastric acid and pepsin in man.. Gut 26:6, pages 594-598.
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Jacques Belaiche, Daniel Cattan, Jacqueline Zittoun, Jeannine Marquet & Jeannine Yvart. (1983) Effect of ranitidine on cobalamin absorption. Digestive Diseases and Sciences 28:7, pages 667-668.
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Eugene M. SorkinDiane L. Darvey. (2017) Review of Cimetidine Drug Interactions. Drug Intelligence & Clinical Pharmacy 17:2, pages 110-120.
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