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Original Article

Fecal Free and Conjugated Bile Acids and Neutral Sterols in Vegetarians, Omnivores, and Patients with Colorectal Cancer

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Pages 277-283 | Received 26 May 1987, Accepted 20 Oct 1987, Published online: 08 Jul 2009

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Dong Geun Lee, Shota Hori, Ohji Kohmoto, Shinri Kitta, Ryo Yoshida, Yasutake Tanaka, Hidehisa Shimizu, Keisuke Takahashi, Taizo Nagura, Hirokatsu Uchino, Satoru Fukiya, Atsushi Yokota & Satoshi Ishizuka. (2019) Ingestion of difructose anhydride III partially suppresses the deconjugation and 7α-dehydroxylation of bile acids in rats fed with a cholic acid-supplemented diet. Bioscience, Biotechnology, and Biochemistry 83:7, pages 1329-1335.
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Herman Adlercreutz. (2007) Lignans and Human Health. Critical Reviews in Clinical Laboratory Sciences 44:5-6, pages 483-525.
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Piero Dolara, Giovanna Caderni, Maddalena Salvadori, Guido Morozzi, Roberto Fabiani, Alberto Cresci, Carla Orpianesi, Giacomo Trallori, Antonio Russo & Domenico Palli. (2002) Fecal Levels of Short-Chain Fatty Acids and Bile Acids as Determinants of Colonic Mucosal Cell Proliferation in Humans. Nutrition and Cancer 42:2, pages 186-190.
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Herman Adlercreutz & Witold Mazur. (1997) Phyto-oestrogens and Western Diseases. Annals of Medicine 29:2, pages 95-120.
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Paul Rozen, Vivian Liberman, Flora Lubin, Samuel Angel, Robert Owen, Naomi Trostler, Tamar Shkolnik & David Kritchevsky. (1996) A new dietary model to study colorectal carcinogenesis: Experimental design, food preparation, and experimental findings. Nutrition and Cancer 25:1, pages 79-100.
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A. Venketeshewer Rao & SusanA. Janezic. (1992) The role of dietary phytosterols in colon carcinogenesis. Nutrition and Cancer 18:1, pages 43-52.
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Herman Adlercreutz. (1990) Western diet and Western diseases: Some hormonal and biochemical mechanisms and associations. Scandinavian Journal of Clinical and Laboratory Investigation 50:sup201, pages 3-23.
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Articles from other publishers (32)

Miljana Nenkov, Yunxia Ma, Nikolaus Gaßler & Yuan Chen. (2021) Metabolic Reprogramming of Colorectal Cancer Cells and the Microenvironment: Implication for Therapy. International Journal of Molecular Sciences 22:12, pages 6262.
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Jose Liñares-Blanco, Cristian R. Munteanu, Alejandro Pazos & Carlos Fernandez-Lozano. (2020) Molecular docking and machine learning analysis of Abemaciclib in colon cancer. BMC Molecular and Cell Biology 21:1.
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Yaqin Zhang, Xiaotong Zhao, Lili Deng, Xueting Li, Ganbiao Wang, Yongxing Li & Mingwei Chen. (2019) High expression of FABP4 and FABP6 in patients with colorectal cancer. World Journal of Surgical Oncology 17:1.
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María Cuevas-Tena, José D. Bermúdez, Ramona de los Ángeles Silvestre, Amparo Alegría & María Jesús Lagarda. (2019) Impact of colonic fermentation on sterols after the intake of a plant sterol-enriched beverage: A randomized, double-blind crossover trial. Clinical Nutrition 38:4, pages 1549-1560.
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Maria Cuevas‐Tena, Amparo Alegría & Maria J. Lagarda. (2018) Relationship Between Dietary Sterols and Gut Microbiota: A Review. European Journal of Lipid Science and Technology 120:12, pages 1800054.
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María Cuevas-Tena, Eva María Gómez del Pulgar, Alfonso Benítez-Páez, Yolanda Sanz, Amparo Alegría & María Jesús Lagarda. (2018) Plant sterols and human gut microbiota relationship: An in vitro colonic fermentation study. Journal of Functional Foods 44, pages 322-329.
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Herman Adlercreutz & Cecilie Kyrø. 2014. Rye and Health. Rye and Health 247 260 .
Christian G. Daughton. (2012) Real-time estimation of small-area populations with human biomarkers in sewage. Science of The Total Environment 414, pages 6-21.
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Bianka Ditscheid, Sylvia Keller & Gerhard Jahreis. (2008) Faecal steroid excretion in humans is affected by calcium supplementation and shows gender-specific differences. European Journal of Nutrition 48:1, pages 22-30.
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Olaf Ortmann & Oliver Treeck. 2009. Klinische Endokrinologie für Frauenärzte. Klinische Endokrinologie für Frauenärzte 599 631 .
Jin Lu TongZhi Hua RanJun ShenGuo Quan FanShu Dong Xiao. (2008) Association between Fecal Bile Acids and Colorectal Cancer: A Meta-analysis of Observational Studies. Yonsei Medical Journal 49:5, pages 792.
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Takahiro Ohmachi, Hiroshi Inoue, Koshi Mimori, Fumiaki Tanaka, Atsushi Sasaki, Tatsuo Kanda, Hiroshi Fujii, Katsuhiko Yanaga & Masaki Mori. (2006) Fatty Acid Binding Protein 6 Is Overexpressed in Colorectal Cancer. Clinical Cancer Research 12:17, pages 5090-5095.
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Muthaiyan Kamaleeswari, Kumaraswami Deeptha, Murugan Sengottuvelan & Namasivayam Nalini. (2006) Effect of dietary caraway (Carum carvi L.) on aberrant crypt foci development, fecal steroids, and intestinal alkaline phosphatase activities in 1,2-dimethylhydrazine-induced colon carcinogenesis. Toxicology and Applied Pharmacology 214:3, pages 290-296.
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Vassiliki Costarelli, Tom Sanders & Sheela Reddy. (2006) Fasting plasma bile acid concentrations in Asian vegetarians, Caucasian vegetarians and Caucasian omnivores. Nutrition & Food Science 36:3, pages 153-158.
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Samira Jean-Louis, Sandeep Akare, M. Ahad Ali, Eugene A. MashJr.Jr., Emmanuelle Meuillet & Jesse D. Martinez. (2006) Deoxycholic Acid Induces Intracellular Signaling through Membrane Perturbations. Journal of Biological Chemistry 281:21, pages 14948-14960.
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Daniel Lechner, Enikö Kállay & Heide S. Cross. 2005. 169 198 .
O. Ortmann. 2005. Klinische Endokrinologie für Frauenärzte. Klinische Endokrinologie für Frauenärzte 527 557 .
Rama Pai, Andrzej S. Tarnawski & Teresa Tran. (2004) Deoxycholic Acid Activates β-Catenin Signaling Pathway and Increases Colon Cell Cancer Growth and Invasiveness. Molecular Biology of the Cell 15:5, pages 2156-2163.
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Graeme H McIntosh, Manny Noakes, Peter J Royle & Paul R Foster. (2003) Whole-grain rye and wheat foods and markers of bowel health in overweight middle-aged men,,. The American Journal of Clinical Nutrition 77:4, pages 967-974.
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Young Tae Ahn, Geun Bae Kim, Kwang Sei Lim, Young Jin Baek & Hyun Uk Kim. (2003) Deconjugation of bile salts by Lactobacillus acidophilus isolates. International Dairy Journal 13:4, pages 303-311.
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Theo M.C.M de Kok & Jan M.S van Maanen. (2000) Evaluation of fecal mutagenicity and colorectal cancer risk. Mutation Research/Reviews in Mutation Research 463:1, pages 53-101.
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Vieno Piironen, David G Lindsay, Tatu A Miettinen, Jari Toivo & Anna-Maija Lampi. (2000) Plant sterols: biosynthesis, biological function and their importance to human nutrition. Journal of the Science of Food and Agriculture 80:7, pages 939-966.
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I. De Smet, P. De Boever & W. Verstraete. (2007) Cholesterol lowering in pigs through enhanced bacterial bile salt hydrolase activity. British Journal of Nutrition 79:2, pages 185-194.
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Freimut A. LeidenbergerFreimut A. Leidenberger. 1998. Klinische Endokrinologie für Frauenärzte. Klinische Endokrinologie für Frauenärzte 527 551 .
Stephen F. Baron & Phillip B. Hylemon. 1997. Gastrointestinal Microbiology. Gastrointestinal Microbiology 470 510 .
GRAEME H. MCINTOSH, RICHARD K. LE LEU, PETER J. ROYLE & GRAEME P. YOUNG. (2008) A comparative study of the influence of differing barley brans on DMH‐induced intestinal tumours in male Sprague‐Dawley rats. Journal of Gastroenterology and Hepatology 11:2, pages 113-119.
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Adriano Tocchi, Luigi Basso, Gianluca Costa, Luca Lepre, Gianluca Liotta, Gianluca Mazzoni, Adalgisa Sita & Sandro Tagliacozzo. (1996) Is there a causal connection between bile acids and colorectal cancer?. Surgery Today 26:2, pages 101-104.
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H Adlercreutz. (1995) Phytoestrogens: epidemiology and a possible role in cancer protection.. Environmental Health Perspectives 103:suppl 7, pages 103-112.
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G. Martin Benson, Neville J. Haskins, Christine Eckers, Peter J. Moore, David G. Reid, Robert C. Mitchell, Sunil Waghmare & Keith E. Suckling. (1993) Polydeoxycholate in human and hamster feces: a major product of cholate metabolism.. Journal of Lipid Research 34:12, pages 2121-2134.
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Jie-Xian Zhang, Göran Hallmans, Herman Adlercreutz, Per Åman, Eric Westerland, Eva Lundin & Roger Stenling. (2007) Effects of oat rye fractions on biliary and faecal bile acid profiles in Syrian golden hamsters ( Mesocricetus auratus ) . British Journal of Nutrition 70:2, pages 525-536.
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Jukka T. Korpela, Riitta Korpela & Herman Adlercreutz. (1992) Fecal bile acid metabolic pattern after administration of different types of bread. Gastroenterology 103:4, pages 1246-1253.
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T.M.C.M. de Kok, P.J. Levels, A. van Faassen, M. Hazen, F. ten Hoor & J.C.S. Kleinjans. (1992) Chromatographic methods for the determination of toxicants in faeces. Journal of Chromatography B: Biomedical Sciences and Applications 580:1-2, pages 135-159.
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