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Original Article

The Ratio of Pepsinogen A to Pepsinogen C: A Sensitive Test for Atrophic Gastritis

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Pages 870-876 | Received 30 Jan 1989, Accepted 18 Mar 1989, Published online: 08 Jul 2009

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Lars Agréus, Ernst J Kuipers, Limas Kupcinskas, Peter Malfertheiner, Francesco Di Mario, Marcis Leja, Varocha Mahachai, Niv Yaron, Martijn van Oijen, Guillermo Perez Perez, Massimo Rugge, Jukka Ronkainen, Mikko Salaspuro, Pentti Sipponen, Kentaro Sugano & Joseph Sung. (2012) Rationale in diagnosis and screening of atrophic gastritis with stomach-specific plasma biomarkers. Scandinavian Journal of Gastroenterology 47:2, pages 136-147.
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Catharina Lewerin, Stefan Jacobsson, Göran Lindstedt & Herman Nilsson-Ehle. (2008) Serum biomarkers for atrophic gastritis and antibodies against Helicobacter pylori in the elderly: Implications for vitamin B12, folic acid and iron status and response to oral vitamin therapy. Scandinavian Journal of Gastroenterology 43:9, pages 1050-1056.
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Pentti Sipponen & David Y. Graham. (2007) Importance of atrophic gastritis in diagnostics and prevention of gastric cancer: Application of plasma biomarkers. Scandinavian Journal of Gastroenterology 42:1, pages 2-10.
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P. Sipponen, F. Laxén, K. Huotari & M. Härkönen. (2003) Prevalence of low vitamin B12 and high homocysteine in serum in an elderly male population: association with atrophic gastritis and Helicobacter pylori infection. Scandinavian Journal of Gastroenterology 38:12, pages 1209-1216.
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A. Korstanje, G. den Hartog, I. Biemond & C. B. H. W. Lamers. (2002) The Serological Gastric Biopsy: a Non-Endoscopical Diagnostic Approach in Management of the Dyspeptic Patient Significance for Primary Care Based on a Survey of the Literature. Scandinavian Journal of Gastroenterology 37:236, pages 22-26.
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Y. Kuwahara, S. Kono, H. Eguchi, H. Hamada, K. Shinchi, K. Imanishi. (2000) Relationship between Serologically Diagnosed Chronic Atrophic Gastritis, Helicobacter pylori, and Environmental Factors in Japanese Men. Scandinavian Journal of Gastroenterology 35:5, pages 476-481.
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K. Varis, P. Sipponen, F. Laxén, I. M. Samloff, J. K. Huttunen, P. R. Taylor, O. P. Heinonen, D. Albanes, N. Sande, J. Virtamo, M. Härkönen. (2000) Implications of Serum Pepsinogen I in Early Endoscopic Diagnosis of Gastric Cancer and Dysplasia. Scandinavian Journal of Gastroenterology 35:9, pages 950-956.
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M. Janssen, B. A. C. Dijkmans, J. P. Vandenbroucke, I. Biemond, W. van Duyn, A. H. Zwinderman & C. B. H. W. Lamers. (1995) Serum Values of Pepsinogens and Antibodies to Helicobacter Pylori in Relation to a History of Peptic Ulcer Disease and NSAID Use. Scandinavian Journal of Rheumatology 24:4, pages 204-208.
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I. Biemond, J. Kreuning, J. B. M. J. Jansen & C. B. H. W. Lamers. (1994) Serum Pepsinogens in Patients with Gastric Diseases or after Gastric Surgery. Scandinavian Journal of Gastroenterology 29:3, pages 238-242.
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Ebba Nexø, Mads Hansen, Karsten Rasmussen, Anders Lindgren & Ralph Gräsbeck. (1994) How to diagnose cobalamin deficiency. Scandinavian Journal of Clinical and Laboratory Investigation 54:sup219, pages 61-76.
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C. K. Axelsson. (1992) Clinical implications of serum pepsinogen and progastricsin in Man. Scandinavian Journal of Clinical and Laboratory Investigation 52:sup210, pages 81-96.
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P. B. Szecsi. (1992) The aspartic proteases. Scandinavian Journal of Clinical and Laboratory Investigation 52:sup210, pages 5-22.
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P. Burman, F. A. Karlsson, L. Lööf, P. B. Szesci & K. Borch. (1991) H+ K+-ATPase Antibodies in Autoimmune Gastritis: Observations on the Development of Pernicious Anemia. Scandinavian Journal of Gastroenterology 26:2, pages 207-214.
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J. Andersen & M. Ström. (1990) A Technique for Screening of Achlorhydria and Hypochlorhydria during Upper Gastrointestinal Endoscopy. Scandinavian Journal of Gastroenterology 25:10, pages 1084-1088.
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Kurt Borch. (1989) Atrophic Gastritis and Gastric Carcinoid Tumours. Annals of Medicine 21:4, pages 291-297.
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